JP4327301B2 - 形質転換微生物、ｄ−アミノアシラーゼの製造方法 - Google Patents

形質転換微生物、ｄ−アミノアシラーゼの製造方法 Download PDF

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JP4327301B2
JP4327301B2 JP17055599A JP17055599A JP4327301B2 JP 4327301 B2 JP4327301 B2 JP 4327301B2 JP 17055599 A JP17055599 A JP 17055599A JP 17055599 A JP17055599 A JP 17055599A JP 4327301 B2 JP4327301 B2 JP 4327301B2
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Prior art keywords
aminoacylase
gene
zinc
producing
medium
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Expired - Fee Related
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JP17055599A
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English (en)
Japanese (ja)
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JP2001000185A5 (enExample
JP2001000185A (ja
Inventor
賢一 竹内
芳直 小出
芳彦 広瀬
充瞭 森口
公安 磯部
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Amano Enzyme Inc
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Amano Enzyme Inc
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Priority to JP17055599A priority Critical patent/JP4327301B2/ja
Application filed by Amano Enzyme Inc filed Critical Amano Enzyme Inc
Priority to EP00937269A priority patent/EP1188823B1/en
Priority to PCT/JP2000/003932 priority patent/WO2000078926A1/ja
Priority to CNB008116105A priority patent/CN100335615C/zh
Priority to US10/009,782 priority patent/US6943004B1/en
Priority to DE60042741T priority patent/DE60042741D1/de
Publication of JP2001000185A publication Critical patent/JP2001000185A/ja
Publication of JP2001000185A5 publication Critical patent/JP2001000185A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
JP17055599A 1999-06-17 1999-06-17 形質転換微生物、ｄ−アミノアシラーゼの製造方法 Expired - Fee Related JP4327301B2 (ja)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP17055599A JP4327301B2 (ja) 1999-06-17 1999-06-17 形質転換微生物、ｄ−アミノアシラーゼの製造方法
PCT/JP2000/003932 WO2000078926A1 (fr) 1999-06-17 2000-06-15 Micro-organisme transforme et procede de production de d-aminoacylase
CNB008116105A CN100335615C (zh) 1999-06-17 2000-06-15 转化微生物、d－酰化氨基酸水解酶的制备方法
US10/009,782 US6943004B1 (en) 1999-06-17 2000-06-15 Transformed microorganism and process for producing D-aminoacylase
EP00937269A EP1188823B1 (en) 1999-06-17 2000-06-15 Transformed microorganism and process for producing d-aminoacylase
DE60042741T DE60042741D1 (de) 1999-06-17 2000-06-15 Transformierte mikroorganismen und verfahren zur herstellung von d-aminoacylase

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP17055599A JP4327301B2 (ja) 1999-06-17 1999-06-17 形質転換微生物、ｄ−アミノアシラーゼの製造方法

Publications (3)

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JP2001000185A JP2001000185A (ja) 2001-01-09
JP2001000185A5 JP2001000185A5 (enExample) 2006-05-18
JP4327301B2 true JP4327301B2 (ja) 2009-09-09

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JP17055599A Expired - Fee Related JP4327301B2 (ja) 1999-06-17 1999-06-17 形質転換微生物、ｄ−アミノアシラーゼの製造方法

Country Status (6)

Country Link
US (1) US6943004B1 (enExample)
EP (1) EP1188823B1 (enExample)
JP (1) JP4327301B2 (enExample)
CN (1) CN100335615C (enExample)
DE (1) DE60042741D1 (enExample)
WO (1) WO2000078926A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20020087948A (ko) * 2001-02-01 2002-11-23 미쯔이가가꾸가부시끼가이샤 신규 ｄ-아미노아실라제를 코딩하는 ｄｎａ 및 그것을사용한 ｄ-아미노산의 제조 방법
EP1574568A4 (en) * 2002-12-18 2006-10-11 Daiichi Pure Chemicals Co Ltd D-aminoacylase
EP1435388B1 (en) * 2002-12-24 2012-12-12 Daicel Corporation D-aminoacylase mutants from Alcaligenes denitrificans for improved D-amino acid production.
JP4513967B2 (ja) * 2005-03-17 2010-07-28 東洋紡績株式会社 Ｄ−アミノアシラーゼの活性向上方法
JP5334044B2 (ja) * 2008-12-26 2013-11-06 学校法人立命館 Ｄ−アミノアシラーゼ及びそれを用いたｄ−アミノ酸の製造方法
CN108624577B (zh) * 2017-03-22 2021-07-27 中国科学院天津工业生物技术研究所 用于催化n-乙酰-d-色氨酸水解生成d-色氨酸的新酶

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0691820B2 (ja) * 1986-01-13 1994-11-16 ナガセ生化学工業株式会社 アミノアシラ−ゼ溶液の安定化法
US5589386A (en) * 1988-08-26 1996-12-31 Serdar; Cuneyt M. Hydrolysis of cholinesterase inhibitors using parathion hydrolase
JPH105488A (ja) * 1996-06-21 1998-01-13 Kiyoshi Okamura お茶刈り袋の大型洗濯機
JP4063400B2 (ja) * 1997-07-31 2008-03-19 ダイセル化学工業株式会社 Ｄ−アミノアシラーゼ
JPH11318442A (ja) * 1998-03-17 1999-11-24 Daicel Chem Ind Ltd Ｄ―アミノアシラ―ゼ
JP2000041684A (ja) * 1998-07-29 2000-02-15 Daicel Chem Ind Ltd 新規なｄ−アミノアシラーゼおよびその製造方法、並びに該ｄ−アミノアシラーゼを利用したｄ−アミノ酸の製造方法

Also Published As

Publication number Publication date
WO2000078926A1 (fr) 2000-12-28
EP1188823A1 (en) 2002-03-20
CN100335615C (zh) 2007-09-05
US6943004B1 (en) 2005-09-13
CN1514876A (zh) 2004-07-21
EP1188823B1 (en) 2009-08-12
JP2001000185A (ja) 2001-01-09
EP1188823A4 (en) 2003-01-22
DE60042741D1 (de) 2009-09-24

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