JP4316373B2 - ヒトのアセチルコリンエステラーゼ(ache)に対するアンチセンスオリゴヌクレオチド及びその使用 - Google Patents

ヒトのアセチルコリンエステラーゼ(ache)に対するアンチセンスオリゴヌクレオチド及びその使用 Download PDF

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JP4316373B2
JP4316373B2 JP2003509100A JP2003509100A JP4316373B2 JP 4316373 B2 JP4316373 B2 JP 4316373B2 JP 2003509100 A JP2003509100 A JP 2003509100A JP 2003509100 A JP2003509100 A JP 2003509100A JP 4316373 B2 JP4316373 B2 JP 4316373B2
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ache
antisense
muscle
mrna
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ソレク・ヘルモナ
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イスム リサーチ ディベロップメント カンパニー オブ ザ ヘブライ ユニバーシティ オブ エルサレム
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    • C12N15/1137Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C12Y301/00Hydrolases acting on ester bonds (3.1)
    • C12Y301/01Carboxylic ester hydrolases (3.1.1)
    • C12Y301/01007Acetylcholinesterase (3.1.1.7)
    • AHUMAN NECESSITIES
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JP2003509100A 2001-05-24 2002-05-23 ヒトのアセチルコリンエステラーゼ(ache)に対するアンチセンスオリゴヌクレオチド及びその使用 Expired - Fee Related JP4316373B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL143379A IL143379A (en) 2001-05-24 2001-05-24 Oligonucleotide against human ache isoform r and its uses
PCT/IL2002/000411 WO2003002739A1 (en) 2001-05-24 2002-05-23 Antisense oligonucleotide against human acetylcholinesterase (ache) and uses thereof

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JP2004536103A JP2004536103A (ja) 2004-12-02
JP2004536103A5 JP2004536103A5 (https=) 2006-01-05
JP4316373B2 true JP4316373B2 (ja) 2009-08-19

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US (3) US7074915B2 (https=)
EP (1) EP1390493B1 (https=)
JP (1) JP4316373B2 (https=)
AU (1) AU2002256873B2 (https=)
CA (1) CA2458806C (https=)
ES (1) ES2397302T3 (https=)
IL (1) IL143379A (https=)
NZ (1) NZ529549A (https=)
WO (1) WO2003002739A1 (https=)

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