JP4307723B2 - Ｎ１−修飾グリコペプチド - Google Patents

Ｎ１−修飾グリコペプチド Download PDF

Info

Publication number
JP4307723B2
JP4307723B2 JP2000546785A JP2000546785A JP4307723B2 JP 4307723 B2 JP4307723 B2 JP 4307723B2 JP 2000546785 A JP2000546785 A JP 2000546785A JP 2000546785 A JP2000546785 A JP 2000546785A JP 4307723 B2 JP4307723 B2 JP 4307723B2
Authority
JP
Japan
Prior art keywords
pharmaceutically acceptable
acceptable salt
compound according
phenyl
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2000546785A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002513764A5 (enExample
JP2002513764A (ja
Inventor
リチャード・クレイグ・トンプソン
スティーブン・チャールズ・ウィルキー
Original Assignee
イーライ リリー アンド カンパニー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by イーライ リリー アンド カンパニー filed Critical イーライ リリー アンド カンパニー
Publication of JP2002513764A publication Critical patent/JP2002513764A/ja
Publication of JP2002513764A5 publication Critical patent/JP2002513764A5/ja
Application granted granted Critical
Publication of JP4307723B2 publication Critical patent/JP4307723B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
    • C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
JP2000546785A 1998-05-01 1999-02-26 Ｎ１−修飾グリコペプチド Expired - Fee Related JP4307723B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8387998P 1998-05-01 1998-05-01
US60/083,879 1998-05-01
PCT/US1999/004306 WO1999056760A1 (en) 1998-05-01 1999-02-26 N1-modified glycopeptides

Publications (3)

Publication Number Publication Date
JP2002513764A JP2002513764A (ja) 2002-05-14
JP2002513764A5 JP2002513764A5 (enExample) 2006-03-30
JP4307723B2 true JP4307723B2 (ja) 2009-08-05

Family

ID=22181253

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000546785A Expired - Fee Related JP4307723B2 (ja) 1998-05-01 1999-02-26 Ｎ１−修飾グリコペプチド

Country Status (10)

Country Link
US (3) US6670446B1 (enExample)
EP (1) EP1073447B1 (enExample)
JP (1) JP4307723B2 (enExample)
AT (1) ATE361931T1 (enExample)
AU (1) AU2881399A (enExample)
CA (1) CA2330619A1 (enExample)
DE (1) DE69936052T2 (enExample)
DK (1) DK1073447T3 (enExample)
ES (1) ES2283107T3 (enExample)
WO (1) WO1999056760A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1073447B1 (en) * 1998-05-01 2007-05-09 Eli Lilly And Company N1-modified glycopeptides
ES2201825T3 (es) 1998-12-23 2004-03-16 Theravance, Inc. Derivados del glicopeptidos y composiciones farmaceuticas que los contienen.
US6699836B2 (en) 1999-04-02 2004-03-02 The Trustees Of Princeton University Vancomycin analogs
WO2000059528A1 (en) * 1999-04-02 2000-10-12 The Trustees Of Princeton University Desleucyl glycopeptide antibiotics and methods of making same
WO2001058933A2 (en) * 2000-02-11 2001-08-16 Eli Lilly And Company Selective n-acylation of a82846 glycopeptide analogs
AR053347A1 (es) 2005-04-06 2007-05-02 Astrazeneca Ab Derivados de [1,3]tiazolo[4,5-d]pirimidin-2(3h)-ona 5,7-sustituidos
UA90707C2 (en) 2005-04-06 2010-05-25 Астразенека Аб Novel 5-substituted 7-amino-[1,3]thiazolo[4,5-d]pyrimidine derivatives
WO2007035938A2 (en) 2005-09-22 2007-03-29 Medivas, Llc BIS-(α-AMINO)-DIOL-DIESTER-CONTAINING POLY(ESTER AMIDE) AND POLY(ESTER URETHANE) COMPOSITIONS AND METHODS OF USE
WO2007038246A2 (en) 2005-09-22 2007-04-05 Medivas, Llc Solid polymer delivery compositions and methods for use thereof
WO2009123713A1 (en) 2008-04-01 2009-10-08 Cornell University Organo-soluble chitosan salts and chitosan-derived biomaterials prepared thereof

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4698327A (en) 1985-04-25 1987-10-06 Eli Lilly And Company Novel glycopeptide derivatives
US4643987A (en) 1985-08-14 1987-02-17 Eli Lilly And Company Modified glycopeptides
US4639433A (en) 1985-08-14 1987-01-27 Eli Lilly And Company Glycopeptide derivatives
EG18377A (en) * 1986-09-19 1993-04-30 Lilly Co Eli Process for preparing glycopeptide antibiotics
US5534420A (en) 1988-07-28 1996-07-09 Eli Lilly And Company Biotransformation of glycopeptide antibiotics
ZA909847B (en) * 1989-12-13 1992-08-26 Lilly Co Eli Glycopeptide derivatives
TW457248B (en) 1994-01-28 2001-10-01 Lilly Co Eli Glycopeptide antibiotic derivatives
US5952310A (en) * 1997-05-20 1999-09-14 Eli Lilly And Company Glycopeptide hexapeptides
EP1073447B1 (en) * 1998-05-01 2007-05-09 Eli Lilly And Company N1-modified glycopeptides

Also Published As

Publication number Publication date
ES2283107T3 (es) 2007-10-16
DE69936052D1 (de) 2007-06-21
DK1073447T3 (da) 2007-09-03
DE69936052T2 (de) 2008-01-17
EP1073447B1 (en) 2007-05-09
AU2881399A (en) 1999-11-23
US20050037950A1 (en) 2005-02-17
US6939947B2 (en) 2005-09-06
CA2330619A1 (en) 1999-11-11
US6670446B1 (en) 2003-12-30
WO1999056760A1 (en) 1999-11-11
US20060128609A1 (en) 2006-06-15
JP2002513764A (ja) 2002-05-14
ATE361931T1 (de) 2007-06-15
EP1073447A4 (en) 2001-10-04
EP1073447A1 (en) 2001-02-07

Similar Documents

Publication Publication Date Title
EP0816378B1 (en) Glycopeptide antibiotic amide derivatives
JP4240544B2 (ja) アルキル化ヘキサペプチド
JP2008208130A (ja) グリコペプチドホスホネート誘導体を調製する方法
JP2011016820A (ja) グリコペプチドホスホン酸誘導体の塩酸塩
JP4307723B2 (ja) Ｎ１−修飾グリコペプチド
JP4159110B2 (ja) グリコペプチド化合物
JP2001524083A (ja) テイコプラニン誘導体
EP0801075A1 (en) Covalently linked dimers of glycopeptide antibiotics
JP4086326B2 (ja) グリコペプチドの尿素およびチオ尿素誘導体
JP4150430B2 (ja) グリコペプチドのヘキサペプチド
IE911798A1 (en) Use of C63 derivatives of 34-de (acetylglucosaminyl)-34-deoxy-teicoplanin against bacteria resistant to glycopeptide antibiotics
HK1007884B (en) Glycopeptide antibiotic amide derivatives

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20060208

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20060208

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A132

Effective date: 20081104

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20090203

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20090331

A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20090430

R150 Certificate of patent or registration of utility model

Free format text: JAPANESE INTERMEDIATE CODE: R150

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20120515

Year of fee payment: 3

LAPS Cancellation because of no payment of annual fees