JP4294092B2 - テロメア長を測定するための方法 - Google Patents

テロメア長を測定するための方法 Download PDF

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Publication number
JP4294092B2
JP4294092B2 JP50217097A JP50217097A JP4294092B2 JP 4294092 B2 JP4294092 B2 JP 4294092B2 JP 50217097 A JP50217097 A JP 50217097A JP 50217097 A JP50217097 A JP 50217097A JP 4294092 B2 JP4294092 B2 JP 4294092B2
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dna
telomere
cells
telomere length
probe
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Expired - Lifetime
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JP50217097A
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Japanese (ja)
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JPH10507085A5 (enExample
JPH10507085A (ja
Inventor
マイケル アール． コズロウスキー，
カレン アール． プロウズ，
シ−シ ウァン，
シャロン ウォン，
ナム ウォー キム，
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Geron Corp
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Geron Corp
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
JP50217097A 1995-06-07 1996-06-06 テロメア長を測定するための方法 Expired - Lifetime JP4294092B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/479,916 1995-06-07
US08/479,916 US5741677A (en) 1995-06-07 1995-06-07 Methods for measuring telomere length
PCT/US1996/010035 WO1996041016A1 (en) 1995-06-07 1996-06-06 Methods for measuring telomere length

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2007329366A Division JP2008119005A (ja) 1995-06-07 2007-12-20 テロメア長を測定するための方法

Publications (3)

Publication Number Publication Date
JPH10507085A JPH10507085A (ja) 1998-07-14
JPH10507085A5 JPH10507085A5 (enExample) 2004-07-08
JP4294092B2 true JP4294092B2 (ja) 2009-07-08

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ID=23905964

Family Applications (2)

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JP50217097A Expired - Lifetime JP4294092B2 (ja) 1995-06-07 1996-06-06 テロメア長を測定するための方法
JP2007329366A Pending JP2008119005A (ja) 1995-06-07 2007-12-20 テロメア長を測定するための方法

Family Applications After (1)

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JP2007329366A Pending JP2008119005A (ja) 1995-06-07 2007-12-20 テロメア長を測定するための方法

Country Status (7)

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US (2) US5741677A (enExample)
EP (1) EP0774014A4 (enExample)
JP (2) JP4294092B2 (enExample)
AU (1) AU697882B2 (enExample)
CA (1) CA2196898C (enExample)
MX (1) MX9700950A (enExample)
WO (1) WO1996041016A1 (enExample)

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US7270958B2 (en) 1998-09-10 2007-09-18 The Regents Of The University Of Michigan Compositions and methods for analysis of nucleic acids
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WO2000074667A2 (en) * 1999-06-04 2000-12-14 Au Jessie L S Compositions active in telomere damage comprising a taxane and telomerase inhibitor
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US6916621B2 (en) 2002-03-27 2005-07-12 Spectral Genomics, Inc. Methods for array-based comparitive binding assays
US20040234961A1 (en) * 2002-04-22 2004-11-25 Fordyce Colleen A. Telomere length determination and applications
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KR100479264B1 (ko) * 2002-11-01 2005-03-28 한국전자통신연구원 주기적 가열과 냉각을 통한 혼성화 방법 및 이를 사용하는폴리뉴클레오타이드 검출 장치
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US20090131351A1 (en) * 2007-11-16 2009-05-21 Antisoma Research Limited Methods, compositions, and kits for modulating tumor cell proliferation
WO2009138117A1 (en) * 2008-05-12 2009-11-19 Fundación Centro Nacional De Investigaciones Oncológicas Carlos Iii Methods and reagents for the determination of telomere length in a semi-automatic manner of every single cell in a immobilized cell population
US8084203B2 (en) 2008-05-12 2011-12-27 Fundacion Centro Nacional De Investigaciones Oncologicas Carlos Iii Methods for the determination of telomere length in a semi-automatic manner of every single cell in a immobilized cell population
US20090298709A1 (en) * 2008-05-28 2009-12-03 Affymetrix, Inc. Assays for determining telomere length and repeated sequence copy number
PT3029154T (pt) 2008-10-17 2017-12-06 Geron Corp Método para identificação de sensibilidade de um paciente à terapia de inibição da telomerase
CA2748265C (en) 2008-12-22 2018-04-03 University Of Utah Research Foundation Monochrome multiplex quantitative pcr
CN102791877A (zh) * 2009-11-06 2012-11-21 酶学有限公司 使用双链核酸复合物与耐热聚合酶用于合成脱氧核糖核苷酸链的组合物和方法
US20130217585A1 (en) * 2010-08-25 2013-08-22 The Trustees Of The University Of Columbia In The City Of New York Quantitative Total Definition of Biologically Active Sequence Elements
US20120196284A1 (en) * 2010-12-16 2012-08-02 University Of Medicine And Dentistry Of New Jersey Method of Measuring Telomere Length
RU2508407C9 (ru) * 2012-10-10 2014-05-20 Елена Андреевна Чирясова Способ количественной оценки терминальных нуклеотидов g-цепи теломерной днк человека с помощью полимеразной цепной реакции и дуплекс-специфического анализа, наборы синтетических олигонуклеотидных праймеров и зондов для осуществления этого способа
US9200327B2 (en) 2012-11-30 2015-12-01 Geron Corporation Diagnostic markers for treating cell proliferative disorders with telomerase inhibitors
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CN110114070A (zh) 2016-11-23 2019-08-09 诺华公司 使用依维莫司(everolimus)、达托里昔布(dactolisib)或二者增强免疫反应的方法
CN106755429A (zh) * 2016-12-27 2017-05-31 上海三誉生物科技有限公司 一种精确测量人群端粒长度的方法
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Also Published As

Publication number Publication date
AU6272496A (en) 1996-12-30
EP0774014A4 (en) 2002-01-02
CA2196898C (en) 2007-10-30
WO1996041016A1 (en) 1996-12-19
US5741677A (en) 1998-04-21
EP0774014A1 (en) 1997-05-21
AU697882B2 (en) 1998-10-22
MX9700950A (es) 1998-01-31
US5834193A (en) 1998-11-10
CA2196898A1 (en) 1996-12-19
JP2008119005A (ja) 2008-05-29
JPH10507085A (ja) 1998-07-14

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