JPH10507085A5 - - Google Patents

Info

Publication number
JPH10507085A5
JPH10507085A5 JP1997502170A JP50217097A JPH10507085A5 JP H10507085 A5 JPH10507085 A5 JP H10507085A5 JP 1997502170 A JP1997502170 A JP 1997502170A JP 50217097 A JP50217097 A JP 50217097A JP H10507085 A5 JPH10507085 A5 JP H10507085A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1997502170A
Other languages
English (en)
Japanese (ja)
Other versions
JPH10507085A (ja
JP4294092B2 (ja
Filing date
Publication date
Priority claimed from US08/479,916 external-priority patent/US5741677A/en
Application filed filed Critical
Publication of JPH10507085A publication Critical patent/JPH10507085A/ja
Publication of JPH10507085A5 publication Critical patent/JPH10507085A5/ja
Application granted granted Critical
Publication of JP4294092B2 publication Critical patent/JP4294092B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

JP50217097A 1995-06-07 1996-06-06 テロメア長を測定するための方法 Expired - Lifetime JP4294092B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/479,916 1995-06-07
US08/479,916 US5741677A (en) 1995-06-07 1995-06-07 Methods for measuring telomere length
PCT/US1996/010035 WO1996041016A1 (en) 1995-06-07 1996-06-06 Methods for measuring telomere length

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2007329366A Division JP2008119005A (ja) 1995-06-07 2007-12-20 テロメア長を測定するための方法

Publications (3)

Publication Number Publication Date
JPH10507085A JPH10507085A (ja) 1998-07-14
JPH10507085A5 true JPH10507085A5 (enExample) 2004-07-08
JP4294092B2 JP4294092B2 (ja) 2009-07-08

Family

ID=23905964

Family Applications (2)

Application Number Title Priority Date Filing Date
JP50217097A Expired - Lifetime JP4294092B2 (ja) 1995-06-07 1996-06-06 テロメア長を測定するための方法
JP2007329366A Pending JP2008119005A (ja) 1995-06-07 2007-12-20 テロメア長を測定するための方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2007329366A Pending JP2008119005A (ja) 1995-06-07 2007-12-20 テロメア長を測定するための方法

Country Status (7)

Country Link
US (2) US5741677A (enExample)
EP (1) EP0774014A4 (enExample)
JP (2) JP4294092B2 (enExample)
AU (1) AU697882B2 (enExample)
CA (1) CA2196898C (enExample)
MX (1) MX9700950A (enExample)
WO (1) WO1996041016A1 (enExample)

Families Citing this family (73)

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US7270958B2 (en) 1998-09-10 2007-09-18 The Regents Of The University Of Michigan Compositions and methods for analysis of nucleic acids
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US7695904B2 (en) * 2002-01-31 2010-04-13 University Of Utah Research Foundation Reducing non-target nucleic acid dependent amplifications: amplifying repetitive nucleic acid sequences
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US20040234961A1 (en) * 2002-04-22 2004-11-25 Fordyce Colleen A. Telomere length determination and applications
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WO2004035597A2 (en) * 2002-10-16 2004-04-29 Women And Infants Hospital Of Rhode Island, Inc. Methods of assessing the risk of reproductive failure by measuring telomere length
KR100479264B1 (ko) * 2002-11-01 2005-03-28 한국전자통신연구원 주기적 가열과 냉각을 통한 혼성화 방법 및 이를 사용하는폴리뉴클레오타이드 검출 장치
JP5686493B2 (ja) * 2003-01-24 2015-03-18 ユニバーシティ・オブ・ユタUniversity Of Utah テロメアの長さを決定することによって死亡の危険性を予測する方法
US7544470B2 (en) * 2003-05-28 2009-06-09 The Johns Hopkins University Method for finding mutations caused by the insertion of repeated DNAs
US20080108057A1 (en) * 2004-06-22 2008-05-08 Griffith Jeffrey K Allelic imbalance in the diagnosis and prognosis of cancer
US7981607B2 (en) 2004-08-27 2011-07-19 Esoterix Genetic Laboratories LLC Method for detecting recombinant event
US9109256B2 (en) 2004-10-27 2015-08-18 Esoterix Genetic Laboratories, Llc Method for monitoring disease progression or recurrence
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US20100291560A1 (en) * 2007-03-27 2010-11-18 The Johns Hopkins University Methods and compositions for diagnosis and treatment of dyskeratosis congenita and related disorders
EP2191013A1 (en) * 2007-08-10 2010-06-02 Tina Holding APS Method for estimating telomere length
US20090131351A1 (en) * 2007-11-16 2009-05-21 Antisoma Research Limited Methods, compositions, and kits for modulating tumor cell proliferation
CA2723950C (en) * 2008-05-12 2016-07-12 Fundacion Centro Nacional De Investigaciones Oncologicas Carlos Iii Methods and reagents for the determination of telomere length in a semi-automatic manner of every single cell in a immobilized cell population
US8084203B2 (en) 2008-05-12 2011-12-27 Fundacion Centro Nacional De Investigaciones Oncologicas Carlos Iii Methods for the determination of telomere length in a semi-automatic manner of every single cell in a immobilized cell population
US20090298709A1 (en) * 2008-05-28 2009-12-03 Affymetrix, Inc. Assays for determining telomere length and repeated sequence copy number
PT3330383T (pt) 2008-10-17 2020-05-06 Geron Corp Grn163l para utiliização como inibidor de telomerase no tratamento de cancro
JP5840950B2 (ja) 2008-12-22 2016-01-06 ユニバーシティ・オブ・ユタ・リサーチ・ファウンデイション 単色マルチプレックス定量pcr
US20110111462A1 (en) * 2009-11-06 2011-05-12 Stephen Picone Composition and Method for Synthesizing a Deoxyribonucleotide Chain Using a Double Stranded Nucleic Acid Complex with a Thermostable Polymerase
US20130217585A1 (en) * 2010-08-25 2013-08-22 The Trustees Of The University Of Columbia In The City Of New York Quantitative Total Definition of Biologically Active Sequence Elements
US20120196284A1 (en) * 2010-12-16 2012-08-02 University Of Medicine And Dentistry Of New Jersey Method of Measuring Telomere Length
RU2508407C9 (ru) * 2012-10-10 2014-05-20 Елена Андреевна Чирясова Способ количественной оценки терминальных нуклеотидов g-цепи теломерной днк человека с помощью полимеразной цепной реакции и дуплекс-специфического анализа, наборы синтетических олигонуклеотидных праймеров и зондов для осуществления этого способа
US9200327B2 (en) 2012-11-30 2015-12-01 Geron Corporation Diagnostic markers for treating cell proliferative disorders with telomerase inhibitors
RU2735141C2 (ru) 2013-03-15 2020-10-28 Иликсиэджен Терапьютикс, Инк. Способы применения zscan4 для омоложения человеческих клеток
CN105283559A (zh) * 2013-05-22 2016-01-27 端粒诊断公司 短端粒丰度的量度
CN105899232A (zh) 2013-11-13 2016-08-24 诺华股份有限公司 用于增强免疫应答的mTOR抑制剂
EP3087101B1 (en) 2013-12-20 2024-06-05 Novartis AG Regulatable chimeric antigen receptor
US11542488B2 (en) 2014-07-21 2023-01-03 Novartis Ag Sortase synthesized chimeric antigen receptors
WO2016014530A1 (en) 2014-07-21 2016-01-28 Novartis Ag Combinations of low, immune enhancing. doses of mtor inhibitors and cars
KR102255304B1 (ko) 2014-09-26 2021-05-24 삼성전자주식회사 텔로미어 증폭 방법
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US11156599B2 (en) * 2015-03-19 2021-10-26 The Johns Hopkins University Assay for telomere length regulators
EP3297629A1 (en) 2015-05-20 2018-03-28 Novartis AG Pharmaceutical combination of everolimus with dactolisib
BR112019010470A2 (pt) 2016-11-23 2019-09-10 Novartis Ag métodos de realce de resposta imune com everolimo, dactolisib ou ambos
CN106755429A (zh) * 2016-12-27 2017-05-31 上海三誉生物科技有限公司 一种精确测量人群端粒长度的方法
IL303660A (en) 2017-05-02 2023-08-01 Revolution Medicines Inc Rapamycin analogs as mtor inhibitors
WO2019040993A1 (en) * 2017-09-01 2019-03-07 Children's Medical Research Institute TELOMER EVALUATION METHOD
US10098922B1 (en) 2017-11-30 2018-10-16 Optigenex, Inc. Increasing telomere length in a cell
US10596165B2 (en) 2018-02-12 2020-03-24 resTORbio, Inc. Combination therapies
CN118978535A (zh) 2018-05-01 2024-11-19 锐新医药公司 作为mTOR抑制剂的C40-、C28-及C-32连接的雷帕霉素类似物
CA3098698A1 (en) 2018-05-01 2019-11-07 Revolution Medicines, Inc. C26-linked rapamycin analogs as mtor inhibitors
EP3674418A1 (en) * 2018-12-26 2020-07-01 Life Length S.L. Method for measuring telomere associated variables and uses thereof for the diagnosis and/or prognosis of telomeric-associated diseases
WO2021025935A1 (en) * 2019-08-02 2021-02-11 Georgetown University Dna-fish method for measurement of telomere length
JP2025522296A (ja) 2022-05-25 2025-07-15 レヴォリューション・メディスンズ,インコーポレイテッド mTOR阻害剤によりがんを処置する方法
CN117248003B (zh) * 2023-11-13 2024-04-12 元码基因科技(北京)股份有限公司 用于完整端粒扩增子测序的组合物、预文库及其构建方法
CN117230169B (zh) * 2023-11-13 2024-02-13 元码基因科技(北京)股份有限公司 用于长片段端粒序列测序的接头、预文库及其构建方法

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WO1995013382A1 (en) * 1993-11-12 1995-05-18 Geron Corporation Therapy and diagnosis of conditions related to telomere length and/or telomerase activity
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