MX9700950A - Metodos para medir la longitud de un telomero. - Google Patents

Metodos para medir la longitud de un telomero.

Info

Publication number
MX9700950A
MX9700950A MX9700950A MX9700950A MX9700950A MX 9700950 A MX9700950 A MX 9700950A MX 9700950 A MX9700950 A MX 9700950A MX 9700950 A MX9700950 A MX 9700950A MX 9700950 A MX9700950 A MX 9700950A
Authority
MX
Mexico
Prior art keywords
methods
telomere length
probe
telomere
primer extension
Prior art date
Application number
MX9700950A
Other languages
English (en)
Spanish (es)
Other versions
MXPA97000950A (en
Inventor
Michael R Kozlowski
Karen R Prowse
Sy-Shi Wang
Sharon Wong
Nam Woo Kim
Original Assignee
Geron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Geron Corp filed Critical Geron Corp
Publication of MXPA97000950A publication Critical patent/MXPA97000950A/xx
Publication of MX9700950A publication Critical patent/MX9700950A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
MX9700950A 1995-06-07 1996-06-06 Metodos para medir la longitud de un telomero. MX9700950A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08479916 1995-06-07
US08/479,916 US5741677A (en) 1995-06-07 1995-06-07 Methods for measuring telomere length
PCT/US1996/010035 WO1996041016A1 (en) 1995-06-07 1996-06-06 Methods for measuring telomere length

Publications (2)

Publication Number Publication Date
MXPA97000950A MXPA97000950A (en) 1998-01-01
MX9700950A true MX9700950A (es) 1998-01-31

Family

ID=23905964

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9700950A MX9700950A (es) 1995-06-07 1996-06-06 Metodos para medir la longitud de un telomero.

Country Status (7)

Country Link
US (2) US5741677A (enExample)
EP (1) EP0774014A4 (enExample)
JP (2) JP4294092B2 (enExample)
AU (1) AU697882B2 (enExample)
CA (1) CA2196898C (enExample)
MX (1) MX9700950A (enExample)
WO (1) WO1996041016A1 (enExample)

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US5871926A (en) * 1997-04-21 1999-02-16 The University Of New Mexico Sensitive method for measurement of telomeric DNA content in human tissues
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US7270958B2 (en) 1998-09-10 2007-09-18 The Regents Of The University Of Michigan Compositions and methods for analysis of nucleic acids
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US8114850B2 (en) * 1999-04-08 2012-02-14 Advanced Cancer Therapeutics, Llc Antiproliferative activity of G-rich oligonucleotides and method of using same to bind to nucleolin
US7960540B2 (en) * 1999-04-08 2011-06-14 Advanced Cancer Therapeutics, Llc Antiproliferative activity of G-rich oligonucleotides and method of using same to bind to nucleolin
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US20030124549A1 (en) * 2001-10-11 2003-07-03 Xerox Corporation Devices and methods for detecting genetic sequences
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US7695904B2 (en) * 2002-01-31 2010-04-13 University Of Utah Research Foundation Reducing non-target nucleic acid dependent amplifications: amplifying repetitive nucleic acid sequences
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US20040234961A1 (en) * 2002-04-22 2004-11-25 Fordyce Colleen A. Telomere length determination and applications
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WO2004035597A2 (en) * 2002-10-16 2004-04-29 Women And Infants Hospital Of Rhode Island, Inc. Methods of assessing the risk of reproductive failure by measuring telomere length
KR100479264B1 (ko) * 2002-11-01 2005-03-28 한국전자통신연구원 주기적 가열과 냉각을 통한 혼성화 방법 및 이를 사용하는폴리뉴클레오타이드 검출 장치
JP5686493B2 (ja) * 2003-01-24 2015-03-18 ユニバーシティ・オブ・ユタＵｎｉｖｅｒｓｉｔｙ Ｏｆ Ｕｔａｈ テロメアの長さを決定することによって死亡の危険性を予測する方法
US7544470B2 (en) * 2003-05-28 2009-06-09 The Johns Hopkins University Method for finding mutations caused by the insertion of repeated DNAs
US20080108057A1 (en) * 2004-06-22 2008-05-08 Griffith Jeffrey K Allelic imbalance in the diagnosis and prognosis of cancer
US7981607B2 (en) 2004-08-27 2011-07-19 Esoterix Genetic Laboratories LLC Method for detecting recombinant event
US9109256B2 (en) 2004-10-27 2015-08-18 Esoterix Genetic Laboratories, Llc Method for monitoring disease progression or recurrence
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US20100291560A1 (en) * 2007-03-27 2010-11-18 The Johns Hopkins University Methods and compositions for diagnosis and treatment of dyskeratosis congenita and related disorders
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US20090131351A1 (en) * 2007-11-16 2009-05-21 Antisoma Research Limited Methods, compositions, and kits for modulating tumor cell proliferation
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US8084203B2 (en) 2008-05-12 2011-12-27 Fundacion Centro Nacional De Investigaciones Oncologicas Carlos Iii Methods for the determination of telomere length in a semi-automatic manner of every single cell in a immobilized cell population
US20090298709A1 (en) * 2008-05-28 2009-12-03 Affymetrix, Inc. Assays for determining telomere length and repeated sequence copy number
PT3330383T (pt) 2008-10-17 2020-05-06 Geron Corp Grn163l para utiliização como inibidor de telomerase no tratamento de cancro
JP5840950B2 (ja) 2008-12-22 2016-01-06 ユニバーシティ・オブ・ユタ・リサーチ・ファウンデイション 単色マルチプレックス定量ｐｃｒ
US20110111462A1 (en) * 2009-11-06 2011-05-12 Stephen Picone Composition and Method for Synthesizing a Deoxyribonucleotide Chain Using a Double Stranded Nucleic Acid Complex with a Thermostable Polymerase
US20130217585A1 (en) * 2010-08-25 2013-08-22 The Trustees Of The University Of Columbia In The City Of New York Quantitative Total Definition of Biologically Active Sequence Elements
US20120196284A1 (en) * 2010-12-16 2012-08-02 University Of Medicine And Dentistry Of New Jersey Method of Measuring Telomere Length
RU2508407C9 (ru) * 2012-10-10 2014-05-20 Елена Андреевна Чирясова Способ количественной оценки терминальных нуклеотидов g-цепи теломерной днк человека с помощью полимеразной цепной реакции и дуплекс-специфического анализа, наборы синтетических олигонуклеотидных праймеров и зондов для осуществления этого способа
US9200327B2 (en) 2012-11-30 2015-12-01 Geron Corporation Diagnostic markers for treating cell proliferative disorders with telomerase inhibitors
RU2735141C2 (ru) 2013-03-15 2020-10-28 Иликсиэджен Терапьютикс, Инк. Способы применения zscan4 для омоложения человеческих клеток
CN105283559A (zh) * 2013-05-22 2016-01-27 端粒诊断公司 短端粒丰度的量度
CN105899232A (zh) 2013-11-13 2016-08-24 诺华股份有限公司 用于增强免疫应答的mTOR抑制剂
EP3087101B1 (en) 2013-12-20 2024-06-05 Novartis AG Regulatable chimeric antigen receptor
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WO2016014530A1 (en) 2014-07-21 2016-01-28 Novartis Ag Combinations of low, immune enhancing. doses of mtor inhibitors and cars
KR102255304B1 (ko) 2014-09-26 2021-05-24 삼성전자주식회사 텔로미어 증폭 방법
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CN106755429A (zh) * 2016-12-27 2017-05-31 上海三誉生物科技有限公司 一种精确测量人群端粒长度的方法
IL303660A (en) 2017-05-02 2023-08-01 Revolution Medicines Inc Rapamycin analogs as mtor inhibitors
WO2019040993A1 (en) * 2017-09-01 2019-03-07 Children's Medical Research Institute TELOMER EVALUATION METHOD
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CN118978535A (zh) 2018-05-01 2024-11-19 锐新医药公司 作为mTOR抑制剂的C40-、C28-及C-32连接的雷帕霉素类似物
CA3098698A1 (en) 2018-05-01 2019-11-07 Revolution Medicines, Inc. C26-linked rapamycin analogs as mtor inhibitors
EP3674418A1 (en) * 2018-12-26 2020-07-01 Life Length S.L. Method for measuring telomere associated variables and uses thereof for the diagnosis and/or prognosis of telomeric-associated diseases
WO2021025935A1 (en) * 2019-08-02 2021-02-11 Georgetown University Dna-fish method for measurement of telomere length
JP2025522296A (ja) 2022-05-25 2025-07-15 レヴォリューション・メディスンズ，インコーポレイテッド ｍＴＯＲ阻害剤によりがんを処置する方法
CN117248003B (zh) * 2023-11-13 2024-04-12 元码基因科技（北京）股份有限公司 用于完整端粒扩增子测序的组合物、预文库及其构建方法
CN117230169B (zh) * 2023-11-13 2024-02-13 元码基因科技（北京）股份有限公司 用于长片段端粒序列测序的接头、预文库及其构建方法

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Also Published As

Publication number Publication date
AU6272496A (en) 1996-12-30
JP2008119005A (ja) 2008-05-29
US5834193A (en) 1998-11-10
EP0774014A1 (en) 1997-05-21
US5741677A (en) 1998-04-21
JPH10507085A (ja) 1998-07-14
AU697882B2 (en) 1998-10-22
EP0774014A4 (en) 2002-01-02
CA2196898A1 (en) 1996-12-19
CA2196898C (en) 2007-10-30
WO1996041016A1 (en) 1996-12-19
JP4294092B2 (ja) 2009-07-08

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