JP4286325B2 - Ｇｍｐを含む乳原料の処理法 - Google Patents

Ｇｍｐを含む乳原料の処理法 Download PDF

Info

Publication number
JP4286325B2
JP4286325B2 JP50025199A JP50025199A JP4286325B2 JP 4286325 B2 JP4286325 B2 JP 4286325B2 JP 50025199 A JP50025199 A JP 50025199A JP 50025199 A JP50025199 A JP 50025199A JP 4286325 B2 JP4286325 B2 JP 4286325B2
Authority
JP
Japan
Prior art keywords
resin
gmp
liquid
raw material
sweet whey
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP50025199A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002514085A (ja
JP2002514085A5 (https=
Inventor
エルドマン、ペテル
ノイマン、フレット
Original Assignee
ソシエテ・デ・プロデュイ・ネスレ・エス・アー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ソシエテ・デ・プロデュイ・ネスレ・エス・アー filed Critical ソシエテ・デ・プロデュイ・ネスレ・エス・アー
Publication of JP2002514085A publication Critical patent/JP2002514085A/ja
Publication of JP2002514085A5 publication Critical patent/JP2002514085A5/ja
Application granted granted Critical
Publication of JP4286325B2 publication Critical patent/JP4286325B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/14—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment
    • A23C9/146—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment by ion-exchange
    • A23C9/1465—Chromatographic separation of protein or lactose fraction; Adsorption of protein or lactose fraction followed by elution
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J1/00—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites
    • A23J1/20—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from milk, e.g. casein; from whey
    • A23J1/205—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from milk, e.g. casein; from whey from whey, e.g. lactalbumine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4732—Casein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Birds (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Dairy Products (AREA)
  • Peptides Or Proteins (AREA)
  • Confectionery (AREA)
  • Cosmetics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP50025199A 1997-05-27 1998-05-22 Ｇｍｐを含む乳原料の処理法 Expired - Fee Related JP4286325B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP97201607.5 1997-05-27
EP97201607A EP0880902A1 (fr) 1997-05-27 1997-05-27 Procédé de traitement d'une matiére première lactosérique
PCT/EP1998/003176 WO1998053702A1 (fr) 1997-05-27 1998-05-22 Procede de traitement d'une matiere premiere lactique contenant du gmp

Publications (3)

Publication Number Publication Date
JP2002514085A JP2002514085A (ja) 2002-05-14
JP2002514085A5 JP2002514085A5 (https=) 2005-12-08
JP4286325B2 true JP4286325B2 (ja) 2009-06-24

Family

ID=8228378

Family Applications (1)

Application Number Title Priority Date Filing Date
JP50025199A Expired - Fee Related JP4286325B2 (ja) 1997-05-27 1998-05-22 Ｇｍｐを含む乳原料の処理法

Country Status (9)

Country Link
US (1) US6787158B1 (https=)
EP (2) EP0880902A1 (https=)
JP (1) JP4286325B2 (https=)
AU (1) AU746520B2 (https=)
BR (1) BR9809171B1 (https=)
CA (1) CA2288184C (https=)
DE (1) DE69836909T2 (https=)
NZ (1) NZ500848A (https=)
WO (1) WO1998053702A1 (https=)

Families Citing this family (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1048226B1 (en) * 1999-04-29 2005-08-31 Société des Produits Nestlé S.A. Infant formula containing sweet whey protein
CA2371696C (en) * 1999-04-29 2005-11-15 Societe Des Produits Nestle S.A. Composition for an infant formula having a low threonine content
GB9923048D0 (en) * 1999-09-29 1999-12-01 Nestle Sa Composition comprising casein protein and whey protein
WO2002030210A1 (en) * 2000-10-10 2002-04-18 Bopa Ireland Limited A dairy product
AU2002345773A1 (en) * 2001-06-08 2002-12-23 Societe Des Produits Nestle S.A. Sugar-based composition containing caseinoglycomacropeptide
ATE433674T1 (de) * 2003-06-23 2009-07-15 Nestec Sa Säuglingsnährpräparat oder folgemilch
EP1638415B1 (en) * 2003-06-23 2010-12-15 Nestec S.A. Infant or follow-on formula
AU2006233918B2 (en) 2005-04-13 2012-06-21 Nestec S.A. Infant formula with probiotics
EP1870649A1 (en) * 2006-06-20 2007-12-26 Octapharma AG Lyophilisation targetting defined residual moisture by limited desorption energy levels
EP1932437A1 (en) 2006-12-15 2008-06-18 Nestec S.A. Infant formula
FI120953B (fi) * 2007-06-26 2010-05-31 Valio Oy Menetelmä hyvin säilyvän vähälaktoosisen tai laktoosittoman maitotuotteen valmistamiseksi
EP2044851A1 (en) 2007-09-26 2009-04-08 Nestec S.A. Prevention of allergy at weaning
US20110048219A1 (en) * 2007-11-13 2011-03-03 Pyles Robert A Blast-resistant barrier
BRPI0819445A2 (pt) 2007-11-26 2015-12-22 Nestec Sa sistema de nutrição para recém-nascidos adaptado à idade
EP2096115A1 (en) 2008-02-26 2009-09-02 Nestec S.A. Oligosaccharide ingredient
EP2116140A1 (en) * 2008-05-08 2009-11-11 Nestec S.A. Sialic acid to support the immune system in the elderly
CA2740855A1 (en) * 2008-10-20 2010-04-29 Nestec S.A. Nutritional composition with anti-regurgitation properties
US9055752B2 (en) 2008-11-06 2015-06-16 Intercontinental Great Brands Llc Shelf-stable concentrated dairy liquids and methods of forming thereof
BRPI0924051A2 (pt) 2009-01-19 2015-07-21 Nestec Sa Composição nutricional para lactente
BRPI1014923A2 (pt) 2009-04-01 2015-09-01 Nestec Sa Redução do risco de obesidade
AU2010230165B2 (en) 2009-04-02 2015-02-12 Novozymes A/S Process for making a milk-based protein hydrolysate
SG174355A1 (en) 2009-04-03 2011-10-28 Nestec Sa Improvement in promotion of healthy catch-up growth
EP2251031A1 (en) 2009-05-12 2010-11-17 Nestec S.A. Lactoferrin and neuronal health and development in the infant gut
EP2251029A1 (en) 2009-05-12 2010-11-17 Nestec S.A. Lactoferrin and gut neuronal health in adults and/or elderly
EP2251032A1 (en) 2009-05-12 2010-11-17 Nestec S.A. Lactoferrin and brain health and protection in adults
EP2251030A1 (en) 2009-05-12 2010-11-17 Nestec S.A. Lactoferrin and brain health and development in infants
WO2011057336A1 (en) * 2009-11-11 2011-05-19 Oral Health Australia Pty Ltd Antibiofilm glycopeptides
EP2509429A1 (en) 2009-12-08 2012-10-17 Nestec S.A. Infant formula with probiotics and milk fat globule membrane components
WO2012004585A1 (en) * 2010-07-09 2012-01-12 Abdulla Badawy Ingestible formulation comprising glycomacropeptide and at least one of tryptophan, tyrosine and phenylalanine and uses thereof
UA112972C2 (uk) 2010-09-08 2016-11-25 Інтерконтінентал Грейт Брендс ЛЛС Рідкий молочний концентрат з високим вмістом сухих речовин
EP2436389A1 (en) 2010-10-01 2012-04-04 Nestec S.A. Milk-based protein hydrolysates and infant formulae and nutritional compositions made thereof
CA2836241A1 (en) 2011-06-08 2012-12-13 Nestec S.A. Nutritional compositions having exogenous milk fat globule membrane components
US20140377439A1 (en) 2012-02-06 2014-12-25 Arla Foods Amba Low-protein frozen confectionery product
MX2016001225A (es) 2013-09-02 2016-05-24 Nestec Sa Lactoferrina y memoria y velocidad de aprendizaje en niños.
MX381155B (es) 2013-11-29 2025-03-12 Soc Des Produits Nestle S A Star Composiciones nutritivas adaptadas a la edad con un contenido de proteína variable.
RU2692488C1 (ru) * 2013-12-13 2019-06-25 Нестек С.А. Использование модифицированной сладкой молочной сыворотки и детской смеси, содержащей модифицированную сладкую молочную сыворотку, для стимулирования постнатального развития центральной нервной системы и соответствующих когнитивных функций ребенка грудного возраста
AU2013407963B2 (en) 2013-12-16 2019-10-10 Société des Produits Nestlé S.A. Newly identified peptides for use in the induction of oral tolerance in young mammals
WO2015091789A2 (en) 2013-12-19 2015-06-25 Nestec S.A. Nutritional composition to reduce metabolic stress in infants
RU2714051C2 (ru) * 2015-02-09 2020-02-11 Сосьете Де Продюи Нестле С.А. Способ обработки сладкой молочной сыворотки с получением белкового материала, пригодного для приготовления гипоаллергенных детских смесей
EP3255999B1 (en) * 2015-02-09 2023-08-09 Société des Produits Nestlé S.A. Process for treating a sweet whey material containing cgmp and related method for producing a protein material having a targeted tryptophan/threonine ratio
CN107404922B (zh) 2015-03-30 2021-09-14 雀巢产品有限公司 乳基蛋白质水解物及由其制备的组合物
EP3307090B1 (en) 2015-06-12 2020-06-03 Société des Produits Nestlé S.A. Combination of tolerogenic peptides and tfg-b for use in the induction and maintenance of oral tolerance in young mammals
MX2018006289A (es) 2015-12-14 2018-11-09 Nestec Sa Composiciones nutritivas y formulas infantiles para promover la mielinizacion en el cerebro.
AU2016374162A1 (en) 2015-12-14 2018-04-19 Nestec S.A. Nutritional compositions and infant formulas to promote myelination in the brain
EP3389406A1 (en) 2015-12-14 2018-10-24 Nestec S.A. Nutritional compositions and infant formulas to promote myelination in the brain
MX2018006294A (es) 2015-12-14 2018-11-09 Nestec Sa Composiciones nutritivas y formulas infantiles para promover la mielinizacion en el cerebro.
CN108366607A (zh) 2015-12-14 2018-08-03 雀巢产品技术援助有限公司 促进大脑髓鞘形成的营养组合物和婴儿配方食品
WO2017167419A1 (en) 2016-03-30 2017-10-05 Nestec S.A. Compositions comprising minerals and their use
CA3004046A1 (en) 2016-03-30 2017-10-05 Nestec S.A. Compositions comprising vitamins and their use
CA3003656A1 (en) 2016-03-30 2017-10-05 Nestec S.A. Compositions comprising choline and their use
SG11201803027PA (en) 2016-03-30 2018-05-30 Nestec Sa Compositions comprising phospholipid and their use
SG11201803022TA (en) 2016-03-30 2018-05-30 Nestec Sa Compositions comprising fatty acids and their use
EP3582637A1 (en) 2017-02-20 2019-12-25 Société des Produits Nestlé S.A. Nutritional compositions with partially hydrolysed proteins for use in inducing glucose and/or insulin response(s) close to the ones observed with human milk
US20210177031A1 (en) 2017-11-09 2021-06-17 Societe Des Produits Nestle S.A. An array of age-tailored nutritional formula for infants and young children for use in the prevention of sub-optimal body composition
KR20200108829A (ko) 2018-01-16 2020-09-21 프리슬랜드캄피나 네덜란드 비.브이. 저알레르기성 영아용 조제식 및 이의 제조 방법
BR112021009955A2 (pt) 2018-12-19 2021-08-17 Société des Produits Nestlé S.A. Usos de um hidrolisado de proteína parcial do soro de leite, e composição para prevenirou reduzir a perda transepidérmica de água e melhorar a função de barreira da pele
CN114585266A (zh) 2019-10-17 2022-06-03 雀巢产品有限公司 婴儿配方食品
EP4044828B1 (en) 2019-10-17 2024-08-07 Société des Produits Nestlé S.A. Extensively hydrolysed infant formula
US12426617B2 (en) 2019-12-30 2025-09-30 Societe Des Produits Nestle S.A. Infant formula
CA3193370A1 (en) 2020-10-16 2022-04-21 Carine Blanchard Nutritional composition comprising human milk oligosaccharides
JP2023547175A (ja) 2020-11-10 2023-11-09 ソシエテ・デ・プロデュイ・ネスレ・エス・アー 栄養組成物
WO2022223427A1 (en) 2021-04-19 2022-10-27 Société des Produits Nestlé S.A. Use of milk protein fractions as a source of osteopontin
EP4701443A1 (en) 2023-04-28 2026-03-04 Société des Produits Nestlé S.A. Nutritional composition
WO2024227720A1 (en) 2023-04-28 2024-11-07 Société des Produits Nestlé S.A. Nutritional composition
AU2024288910A1 (en) 2023-07-06 2026-01-08 Societe Des Produits Nestle S.A. Combination for dietary management of gut health

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1442298A (en) * 1972-09-01 1976-07-14 Ici Ltd Replenishment of fluidised beds
GB2188526B (en) * 1986-02-19 1990-10-10 Agricultural & Food Res A proteinaceous material obtainable from milk or casein-containing milk products ,process for its production and its use in food and drink
JP2622686B2 (ja) * 1987-05-15 1997-06-18 雪印乳業株式会社 ｋ−カゼイングリコマクロペプチドの製造法
FR2646775A1 (fr) * 1989-05-11 1990-11-16 Centre Nat Rech Scient Utilisation du caseinoglycopeptide k, notamment de lait de vache, pour la fabrication d'une composition, notamment d'un medicament, pour la prevention et le traitement des thromboses
JP3035833B2 (ja) * 1991-01-21 2000-04-24 雪印乳業株式会社 シアル酸類含有組成物の製造方法
JP2961625B2 (ja) * 1991-01-21 1999-10-12 雪印乳業株式会社 α−ラクトアルブミン含有量の高い組成物の製造方法
JP2920427B2 (ja) * 1991-01-21 1999-07-19 雪印乳業株式会社 κ−カゼイングリコマクロペプチドの製造法
JP3123618B2 (ja) * 1992-03-18 2001-01-15 雪印乳業株式会社 新規ペプチド、該ペプチドを有効成分とする胃酸分泌抑制−抗潰瘍剤及び飲食品
JP3161846B2 (ja) * 1992-11-11 2001-04-25 明治乳業株式会社 牛乳ホエ−中のシアル酸結合ペプタイドの分離法
DE4344342C2 (de) * 1993-12-23 1996-08-08 Milupa Ag Molkenprotein-dominante Säuglingsnahrung
US6168823B1 (en) * 1997-10-09 2001-01-02 Wisconsin Alumni Research Foundation Production of substantially pure kappa casein macropeptide
US5968586A (en) * 1997-10-09 1999-10-19 Wisconsin Alumni Research Foundation Production of κ-casein macropeptide for nutraceutical uses

Also Published As

Publication number Publication date
EP0880902A1 (fr) 1998-12-02
EP0986312B1 (fr) 2007-01-17
DE69836909T2 (de) 2007-09-06
CA2288184C (en) 2009-10-27
WO1998053702A1 (fr) 1998-12-03
BR9809171A (pt) 2000-08-01
JP2002514085A (ja) 2002-05-14
NZ500848A (en) 2001-12-21
BR9809171B1 (pt) 2011-01-11
AU746520B2 (en) 2002-05-02
AU8107798A (en) 1998-12-30
US6787158B1 (en) 2004-09-07
DE69836909D1 (de) 2007-03-08
EP0986312A1 (fr) 2000-03-22
CA2288184A1 (en) 1998-12-03

Similar Documents

Publication Publication Date Title
JP4286325B2 (ja) Ｇｍｐを含む乳原料の処理法
CN102482313B (zh) 乳清成分的分离和纯化
US5278288A (en) Process for producing κ-casein glycomacropeptides
JP2673828B2 (ja) κ―カゼイングリコマクロペプチドの製造法
EP0390821B1 (en) Process for extracting pure fractions of lactoperoxidase and lactoferrin from milk serum
US5280107A (en) Process for producing K-casein glycomacropeptides
JP6012053B2 (ja) 濃縮供給物を使用してオステオポンチンを単離する方法
JP2003522539A (ja) 酪農水流の濾過方法
JPS6339545A (ja) 牛乳ホエ−中のβ−ラクトグロブリンの除去方法
JP2961625B2 (ja) α−ラクトアルブミン含有量の高い組成物の製造方法
JPH04316450A (ja) シアル酸類含有組成物の製造方法
AU2016218086B2 (en) Process for treating sweet whey such as to obtain a protein material suitable for hypoallergenic infant formulae
WO2002028194A1 (en) Process for recovering proteins from whey protein containing feedstocks
CN121926352A (zh) 用于处理含有cgmp的甜乳清材料的方法以及用于生产具有目标色氨酸/苏氨酸比例的蛋白质材料的相关方法
JP3106256B2 (ja) κ−カゼイングリコマクロペプチドの製造法
MXPA99010313A (en) Method for treating a lactic raw material containing gmp
WO2002074790A1 (en) Large scale production of low fat and sds gel pure kappa-casein glycomacropeptides (gmp) from bovine deproteinized whey

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20050513

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20050513

A72 Notification of change in name of applicant

Free format text: JAPANESE INTERMEDIATE CODE: A721

Effective date: 20061113

RD02 Notification of acceptance of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7422

Effective date: 20061113

RD05 Notification of revocation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7425

Effective date: 20070314

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20080701

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20081001

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20081110

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20081104

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20081215

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20081201

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20090119

A524 Written submission of copy of amendment under article 19 pct

Free format text: JAPANESE INTERMEDIATE CODE: A524

Effective date: 20090105

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20090317

A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20090325

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20120403

Year of fee payment: 3

R150 Certificate of patent or registration of utility model

Free format text: JAPANESE INTERMEDIATE CODE: R150

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20120403

Year of fee payment: 3

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20130403

Year of fee payment: 4

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20130403

Year of fee payment: 4

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20140403

Year of fee payment: 5

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

LAPS Cancellation because of no payment of annual fees