JP4213383B2 - 活性成分を急速放出するための親水性ポリマーの薄膜状多層薬剤 - Google Patents

活性成分を急速放出するための親水性ポリマーの薄膜状多層薬剤 Download PDF

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Publication number
JP4213383B2
JP4213383B2 JP2001536121A JP2001536121A JP4213383B2 JP 4213383 B2 JP4213383 B2 JP 4213383B2 JP 2001536121 A JP2001536121 A JP 2001536121A JP 2001536121 A JP2001536121 A JP 2001536121A JP 4213383 B2 JP4213383 B2 JP 4213383B2
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Prior art keywords
layer
layers
thin film
polymer
manufacturing
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Expired - Lifetime
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Japanese (ja)
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JP2003513906A (ja
JP2003513906A5 (enExample
Inventor
クルメ、マルカス
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エルティエス ローマン テラピー−ズュステーメ アーゲー
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Publication of JP2003513906A5 publication Critical patent/JP2003513906A5/ja
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/31504—Composite [nonstructural laminate]
    • Y10T428/31855—Of addition polymer from unsaturated monomers
    • Y10T428/31909—Next to second addition polymer from unsaturated monomers
    • Y10T428/31913—Monoolefin polymer
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/31504—Composite [nonstructural laminate]
    • Y10T428/31855—Of addition polymer from unsaturated monomers
    • Y10T428/31909—Next to second addition polymer from unsaturated monomers
    • Y10T428/31928—Ester, halide or nitrile of addition polymer

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Laminated Bodies (AREA)
JP2001536121A 1999-11-11 2000-11-03 活性成分を急速放出するための親水性ポリマーの薄膜状多層薬剤 Expired - Lifetime JP4213383B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19954245A DE19954245A1 (de) 1999-11-11 1999-11-11 Mehrschichtige filmförmige Zubereitung aus hydrophilen Polymeren zur schnellen Freisetzung von Wirkstoffen
DE19954245.7 1999-11-11
PCT/EP2000/010856 WO2001034121A2 (de) 1999-11-11 2000-11-03 Mehrschichtige filmförmige zubereitung aus hydrophilen polymeren zur schnellen freisetzung von wirkstoffen

Publications (3)

Publication Number Publication Date
JP2003513906A JP2003513906A (ja) 2003-04-15
JP2003513906A5 JP2003513906A5 (enExample) 2006-02-09
JP4213383B2 true JP4213383B2 (ja) 2009-01-21

Family

ID=7928670

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001536121A Expired - Lifetime JP4213383B2 (ja) 1999-11-11 2000-11-03 活性成分を急速放出するための親水性ポリマーの薄膜状多層薬剤

Country Status (13)

Country Link
US (2) US7332230B1 (enExample)
EP (1) EP1227801B1 (enExample)
JP (1) JP4213383B2 (enExample)
KR (1) KR100731263B1 (enExample)
CN (1) CN1407886A (enExample)
AR (1) AR026427A1 (enExample)
AT (1) ATE339193T1 (enExample)
AU (1) AU778619B2 (enExample)
CA (1) CA2391406C (enExample)
DE (2) DE19954245A1 (enExample)
ES (1) ES2272344T3 (enExample)
IL (2) IL149573A0 (enExample)
WO (1) WO2001034121A2 (enExample)

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US11207805B2 (en) 2001-10-12 2021-12-28 Aquestive Therapeutics, Inc. Process for manufacturing a resulting pharmaceutical film
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Also Published As

Publication number Publication date
CN1407886A (zh) 2003-04-02
AR026427A1 (es) 2003-02-12
EP1227801B1 (de) 2006-09-13
US7803430B2 (en) 2010-09-28
EP1227801A2 (de) 2002-08-07
JP2003513906A (ja) 2003-04-15
AU1998101A (en) 2001-06-06
DE19954245A1 (de) 2001-07-19
CA2391406C (en) 2008-07-29
ATE339193T1 (de) 2006-10-15
AU778619B2 (en) 2004-12-16
US7332230B1 (en) 2008-02-19
US20080057087A1 (en) 2008-03-06
KR100731263B1 (ko) 2007-06-21
ES2272344T3 (es) 2007-05-01
IL149573A (en) 2007-09-20
WO2001034121A2 (de) 2001-05-17
CA2391406A1 (en) 2001-05-17
KR20020058006A (ko) 2002-07-12
IL149573A0 (en) 2002-11-10
DE50013472D1 (de) 2006-10-26
WO2001034121A3 (de) 2002-04-11

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