JP4199365B2 - 組換え組織因子に基づく、即時使用可能なプロトロンビン時間試薬 - Google Patents

組換え組織因子に基づく、即時使用可能なプロトロンビン時間試薬 Download PDF

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JP4199365B2
JP4199365B2 JP06585699A JP6585699A JP4199365B2 JP 4199365 B2 JP4199365 B2 JP 4199365B2 JP 06585699 A JP06585699 A JP 06585699A JP 6585699 A JP6585699 A JP 6585699A JP 4199365 B2 JP4199365 B2 JP 4199365B2
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reagent
tissue factor
reagent according
human
stability
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Expired - Fee Related
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JP06585699A
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Japanese (ja)
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JPH11316228A (ja
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ノールベルト・ツァンダー
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デイド・ベーリング・マルブルク・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP06585699A 1998-03-13 1999-03-12 組換え組織因子に基づく、即時使用可能なプロトロンビン時間試薬 Expired - Fee Related JP4199365B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19811016:2 1998-03-13
DE19811016A DE19811016A1 (de) 1998-03-13 1998-03-13 Gebrauchsfertiges Prothrombinzeitreagenz auf der Basis von rekombinantem Gewebsfaktor

Publications (2)

Publication Number Publication Date
JPH11316228A JPH11316228A (ja) 1999-11-16
JP4199365B2 true JP4199365B2 (ja) 2008-12-17

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ID=7860840

Family Applications (1)

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JP06585699A Expired - Fee Related JP4199365B2 (ja) 1998-03-13 1999-03-12 組換え組織因子に基づく、即時使用可能なプロトロンビン時間試薬

Country Status (6)

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EP (1) EP0942284B1 (de)
JP (1) JP4199365B2 (de)
AT (1) ATE385315T1 (de)
CA (2) CA2263197A1 (de)
DE (2) DE19811016A1 (de)
ES (1) ES2299224T3 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7049087B2 (en) * 2002-11-05 2006-05-23 Lifescan, Inc. Method for manufacturing a tissue factor-based prothrombin time reagent
JP4377207B2 (ja) * 2003-11-28 2009-12-02 シスメックス株式会社 血液凝固時間測定方法および血液凝固時間測定用試薬
US7148067B2 (en) * 2004-08-31 2006-12-12 The Board Of Trustees Of The University Of Illinois Thromboplastin reagents
DE602006021290D1 (de) 2005-03-04 2011-05-26 Univ Illinois Modulator von coagulationskaskaden und fibrinolytischen kaskaden
WO2009046194A2 (en) 2007-10-05 2009-04-09 The Board Of Trustees Of The University Of Illinois Fibrin sealant
WO2009061697A1 (en) 2007-11-09 2009-05-14 The Board Of Trustees Of The University Of Illinois Anticoagulant antagonist and hemophilia procoagulant
DE102007062323A1 (de) * 2007-12-21 2009-06-25 Siemens Healthcare Diagnostics Products Gmbh Langzeitstabiles Thromboplastin-Reagenz
PL2528617T3 (pl) 2010-01-28 2016-09-30 Interleukina-2 lub interferon-alfa do zastosowania w leczeniu uzależnienia od nikotyny lub jedzenia
JP6116231B2 (ja) * 2012-12-25 2017-04-19 株式会社Ｌｓｉメディエンス 組織トロンボプラスチン含有血液凝固能測定試薬及び測定方法
EP2772762B1 (de) * 2013-02-28 2016-11-30 Siemens Healthcare Diagnostics Products GmbH Verfahren zur Bestimmung der Protein S-Aktivität
JP6250306B2 (ja) * 2013-05-28 2017-12-20 株式会社Ｌｓｉメディエンス リポ化トロンボプラスチン含有血液凝固能測定試薬及び測定方法
AU2017217804B2 (en) 2016-02-12 2020-10-22 Instrumentation Laboratory Company A two component "mix and use" liquid thromboplastin reagent, methods of making, and methods of use thereof
EP3489692A1 (de) 2017-11-28 2019-05-29 Siemens Healthcare Diagnostics Products GmbH Prothrombinzeit-reagenz enthaltend einen eisenchelator

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3522148A (en) * 1965-08-13 1970-07-28 Dade Reagents Inc Stabilized thromboplastin preparation
US5314695A (en) * 1990-11-13 1994-05-24 Corvas International, Inc. Tissue factor based prothrombin time reagent
US5358853A (en) * 1992-08-03 1994-10-25 Akzo Av Liquid thromboplastin reagent
CA2288058A1 (en) * 1997-04-23 1998-10-29 Instrumentation Laboratory, S.P.A. Recombinant rabbit tissue factor based prothrombin time reagent

Also Published As

Publication number Publication date
CA2265270A1 (en) 1999-09-13
DE19811016A1 (de) 1999-09-16
CA2265270C (en) 2009-11-24
DE59914634D1 (de) 2008-03-20
CA2263197A1 (en) 1999-09-13
ATE385315T1 (de) 2008-02-15
EP0942284A2 (de) 1999-09-15
EP0942284B1 (de) 2008-01-30
ES2299224T3 (es) 2008-05-16
JPH11316228A (ja) 1999-11-16
EP0942284A3 (de) 2005-03-16

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