DE602006021290D1 - Modulator von coagulationskaskaden und fibrinolytischen kaskaden - Google Patents

Modulator von coagulationskaskaden und fibrinolytischen kaskaden

Info

Publication number
DE602006021290D1
DE602006021290D1 DE602006021290T DE602006021290T DE602006021290D1 DE 602006021290 D1 DE602006021290 D1 DE 602006021290D1 DE 602006021290 T DE602006021290 T DE 602006021290T DE 602006021290 T DE602006021290 T DE 602006021290T DE 602006021290 D1 DE602006021290 D1 DE 602006021290D1
Authority
DE
Germany
Prior art keywords
cascades
modulator
fibrinolytic
coagulation
wound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602006021290T
Other languages
English (en)
Inventor
James H Morrissey
Stephanie A Smith
Roberto Docampo
Nicola J Mutch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Illinois
Original Assignee
University of Illinois
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Illinois filed Critical University of Illinois
Publication of DE602006021290D1 publication Critical patent/DE602006021290D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Neurosurgery (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE602006021290T 2005-03-04 2006-02-23 Modulator von coagulationskaskaden und fibrinolytischen kaskaden Active DE602006021290D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65877605P 2005-03-04 2005-03-04
PCT/US2006/006642 WO2006096345A2 (en) 2005-03-04 2006-02-23 Coagulation and fibrinolytic cascades modulator

Publications (1)

Publication Number Publication Date
DE602006021290D1 true DE602006021290D1 (de) 2011-05-26

Family

ID=36648781

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602006021290T Active DE602006021290D1 (de) 2005-03-04 2006-02-23 Modulator von coagulationskaskaden und fibrinolytischen kaskaden

Country Status (8)

Country Link
US (2) US7682808B2 (de)
EP (1) EP1869082B1 (de)
JP (1) JP2008531692A (de)
CN (1) CN101184775A (de)
AT (1) ATE505488T1 (de)
CA (1) CA2600907C (de)
DE (1) DE602006021290D1 (de)
WO (1) WO2006096345A2 (de)

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JP5073270B2 (ja) 2006-11-14 2012-11-14 シスメックス株式会社 凝固検査用試薬及びその製造方法
US20090047366A1 (en) * 2007-08-15 2009-02-19 Bedard Robert L Inorganic Coagulation Accelerators for Individuals taking Platelet Blockers or Anticoagulants
US8821861B2 (en) 2007-10-05 2014-09-02 The Board Of Trustees Of The University Of Illinois Fibrin sealant
WO2009061697A1 (en) 2007-11-09 2009-05-14 The Board Of Trustees Of The University Of Illinois Anticoagulant antagonist and hemophilia procoagulant
DE102007062323A1 (de) * 2007-12-21 2009-06-25 Siemens Healthcare Diagnostics Products Gmbh Langzeitstabiles Thromboplastin-Reagenz
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CN102348462B (zh) * 2008-12-19 2015-06-17 巴克斯特国际公司 Tfpi抑制剂和使用方法
AU2009331570C1 (en) 2008-12-22 2024-04-18 Novo Nordisk A/S Antibodies against tissue factor pathway inhibitor
EP3345615B1 (de) 2010-03-01 2019-10-16 Bayer Healthcare LLC Optimierte monoklonalantikörper gegen tissue factor pathway inhibitor (tfpi)
CN105566490A (zh) 2010-03-19 2016-05-11 巴克斯特国际公司 Tfpi抑制剂及使用方法
CN103124570B (zh) 2010-09-27 2015-04-22 利兹大学 无细胞血管产物
AU2013235741C1 (en) 2012-03-21 2017-12-21 Takeda Pharmaceutical Company Limited TFPI inhibitors and methods of use
DK2964329T3 (da) 2013-03-08 2020-03-16 Univ California Polyphosphat-funktionaliserede uorganiske nanopartikler som hæmostatiske sammensætninger og anvendelsesfremgangsmåder
DE102013222223A1 (de) * 2013-10-31 2015-04-30 Bk Giulini Gmbh Blutstillendes Mittel enthaltend kristallines Polyphosphat
US9408871B2 (en) * 2013-11-08 2016-08-09 The University Of British Columbia Methods for inhibiting complement activation and uses thereof
US11112145B2 (en) 2014-09-24 2021-09-07 The Board Of Trustees Of The University Of Illinois Artificial platelets for treating catastrophic bleeding
JP7101351B2 (ja) * 2016-04-28 2022-07-15 シスメックス株式会社 血液検体の分析方法、血液検体分析用試薬及び試薬キット、並びに血液検体分析装置
US11519917B2 (en) 2017-04-13 2022-12-06 The Regents Of The University Of Michigan Assay for quantifying polyphosphates
DK3897758T3 (da) * 2018-12-20 2023-04-03 Bk Giulini Gmbh Middel til behandling af blødende sår
CN111856043A (zh) * 2020-08-28 2020-10-30 保定天岳生物工程有限公司 一种凝血酶原时间检测试剂盒

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Also Published As

Publication number Publication date
US20100143492A1 (en) 2010-06-10
ATE505488T1 (de) 2011-04-15
US7682808B2 (en) 2010-03-23
EP1869082A2 (de) 2007-12-26
EP1869082B1 (de) 2011-04-13
CN101184775A (zh) 2008-05-21
US9597375B2 (en) 2017-03-21
CA2600907C (en) 2016-06-28
JP2008531692A (ja) 2008-08-14
WO2006096345A2 (en) 2006-09-14
CA2600907A1 (en) 2006-09-14
US20060198837A1 (en) 2006-09-07
WO2006096345A3 (en) 2006-11-30

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