ATE99543T1 - Pulverfoermige zubereitungen zur intranasalen verabreichung von polypeptiden. - Google Patents

Pulverfoermige zubereitungen zur intranasalen verabreichung von polypeptiden.

Info

Publication number
ATE99543T1
ATE99543T1 AT88117029T AT88117029T ATE99543T1 AT E99543 T1 ATE99543 T1 AT E99543T1 AT 88117029 T AT88117029 T AT 88117029T AT 88117029 T AT88117029 T AT 88117029T AT E99543 T1 ATE99543 T1 AT E99543T1
Authority
AT
Austria
Prior art keywords
polypeptides
intranasal administration
powdered preparations
biologically active
powdered
Prior art date
Application number
AT88117029T
Other languages
English (en)
Inventor
Brian H Vickery
Cherng-Chyi Fu
Eric J Benjamin
Lynda M Sanders
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Application granted granted Critical
Publication of ATE99543T1 publication Critical patent/ATE99543T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Otolaryngology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
AT88117029T 1987-10-15 1988-10-13 Pulverfoermige zubereitungen zur intranasalen verabreichung von polypeptiden. ATE99543T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10967887A 1987-10-15 1987-10-15
EP88117029A EP0312052B1 (de) 1987-10-15 1988-10-13 Pulverförmige Zubereitungen zur intranasalen Verabreichung von Polypeptiden

Publications (1)

Publication Number Publication Date
ATE99543T1 true ATE99543T1 (de) 1994-01-15

Family

ID=22328950

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88117029T ATE99543T1 (de) 1987-10-15 1988-10-13 Pulverfoermige zubereitungen zur intranasalen verabreichung von polypeptiden.

Country Status (11)

Country Link
US (3) US6521597B1 (de)
EP (1) EP0312052B1 (de)
JP (1) JP2851627B2 (de)
KR (1) KR890006252A (de)
AT (1) ATE99543T1 (de)
AU (1) AU623609B2 (de)
CA (1) CA1336401C (de)
DE (1) DE3886880T2 (de)
ES (1) ES2061591T3 (de)
NZ (1) NZ226557A (de)
ZA (1) ZA887658B (de)

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US6632456B1 (en) 1993-06-24 2003-10-14 Astrazeneca Ab Compositions for inhalation
CA2206657C (en) 1994-12-22 2009-05-19 Astra Aktiebolag Therapeutic preparation for inhalation containing parathyroid hormone, pth
EP0806940B1 (de) 1994-12-22 2003-04-09 AstraZeneca AB Aerosol-arzneiformulierungen
US6524557B1 (en) 1994-12-22 2003-02-25 Astrazeneca Ab Aerosol formulations of peptides and proteins
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WO2004073729A1 (ja) 2003-02-21 2004-09-02 Translational Research Ltd. 薬物の経鼻投与用組成物
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EP2327724A3 (de) * 2004-02-02 2011-07-27 Ambrx, Inc. Modifizierte humane Wachstumshormon-Polypeptide und deren Verwendungen
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US7148067B2 (en) * 2004-08-31 2006-12-12 The Board Of Trustees Of The University Of Illinois Thromboplastin reagents
US7115561B2 (en) * 2004-09-22 2006-10-03 Patterson James A Medicament composition and method of administration
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US20080260858A1 (en) * 2005-02-16 2008-10-23 The Board Of Trustees Of The University Of Illnois Universal Procoagulant
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US20070031512A1 (en) * 2005-08-03 2007-02-08 Amcol International Corporation Virus-interacting layered phyllosilicates and methods of inactivating viruses
US20080184618A1 (en) * 2005-08-03 2008-08-07 Amcol International Virus-Interacting Layered Phyllosilicates and Methods of Use
CA2620202C (en) 2005-08-26 2016-10-04 The Board Of Trustees Of The Leland Stanford Junior University Therapy procedure for drug delivery for trigeminal pain
US20080033038A1 (en) * 2006-07-07 2008-02-07 Shytle R D Compositions of polyphenols and methods of use
CN101668544B (zh) 2006-12-26 2013-04-24 株式会社新日本科学 经鼻投用制剂
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WO2009023125A1 (en) * 2007-08-14 2009-02-19 The Board Of Trustees Of The Leland Stanford Junior University Neuronostatin and its uses
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WO2009046194A2 (en) * 2007-10-05 2009-04-09 The Board Of Trustees Of The University Of Illinois Fibrin sealant
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CA2716835A1 (en) 2008-02-27 2009-09-03 Amcol International Corporation Methods of treating cardiovascular disorders associated with atherosclerosis
US9101539B2 (en) * 2009-05-15 2015-08-11 Shin Nippon Biomedical Laboratories, Ltd. Intranasal pharmaceutical compositions with improved pharmacokinetics
GB2472327B (en) * 2009-07-31 2013-03-13 Shin Nippon Biomedical Lab Ltd Intranasal granisetron and nasal applicator
WO2016067252A1 (en) 2014-10-31 2016-05-06 Glaxosmithkline Intellectual Property Development Limited Powder formulation
SG11201705591PA (en) 2015-01-07 2017-08-30 Trigemina Inc Magnesium-containing oxytocin formulations and methods of use
US20160361253A1 (en) * 2015-06-13 2016-12-15 Noveome Biotherapeutics, Inc. Novel Methods for Delivering Therapeutic Agents to the Eye via Nasal Passages
HUE070412T2 (hu) 2016-04-12 2025-06-28 Tonix Pharma Ltd Magnézium tartalmú oxitocin készítmények és alkamazási eljárásaik
US11744967B2 (en) 2017-09-26 2023-09-05 Shin Nippon Biomedical Laboratories, Ltd. Intranasal delivery devices
CN110279656B (zh) * 2019-07-11 2021-11-09 温州医科大学 一种用于缓解鼻腔干燥的组合物及其制备方法和使用方法
TW202210072A (zh) 2020-05-26 2022-03-16 美商羅德科技公司 用於鼻內或吸入遞送之大麻素組合物及劑型

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Also Published As

Publication number Publication date
EP0312052A1 (de) 1989-04-19
KR890006252A (ko) 1989-06-12
EP0312052B1 (de) 1994-01-05
US6815424B2 (en) 2004-11-09
NZ226557A (en) 1990-07-26
US6521597B1 (en) 2003-02-18
US20030181387A1 (en) 2003-09-25
US20050089480A1 (en) 2005-04-28
JP2851627B2 (ja) 1999-01-27
CA1336401C (en) 1995-07-25
AU623609B2 (en) 1992-05-21
DE3886880T2 (de) 1994-07-14
ZA887658B (en) 1990-06-27
ES2061591T3 (es) 1994-12-16
DE3886880D1 (de) 1994-02-17
JPH01132532A (ja) 1989-05-25
AU2375188A (en) 1989-06-01

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EEIH Change in the person of patent owner
EEIH Change in the person of patent owner
EELA Cancelled due to lapse of time