JP4192093B2 - 慢性皮膚潰瘍の治癒を促進する方法 - Google Patents

慢性皮膚潰瘍の治癒を促進する方法 Download PDF

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Publication number
JP4192093B2
JP4192093B2 JP2003518575A JP2003518575A JP4192093B2 JP 4192093 B2 JP4192093 B2 JP 4192093B2 JP 2003518575 A JP2003518575 A JP 2003518575A JP 2003518575 A JP2003518575 A JP 2003518575A JP 4192093 B2 JP4192093 B2 JP 4192093B2
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Japan
Prior art keywords
gly
group
ulcers
wound
asp
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Expired - Fee Related
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JP2003518575A
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English (en)
Japanese (ja)
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JP2004538320A (ja
JP2004538320A5 (enExample
Inventor
カーニー,ダレル,エイチ.
Original Assignee
ザ ボード オブ リージェンツ オブ ザ ユニバーシティ オブ テキサス システム
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Publication of JP2004538320A5 publication Critical patent/JP2004538320A5/ja
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482Serine endopeptidases (3.4.21)
    • A61K38/4833Thrombin (3.4.21.5)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Obesity (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
JP2003518575A 2001-07-27 2002-01-16 慢性皮膚潰瘍の治癒を促進する方法 Expired - Fee Related JP4192093B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30819801P 2001-07-27 2001-07-27
PCT/US2002/001151 WO2003013569A2 (en) 2001-07-27 2002-01-16 Use of thrombin-derived peptides for the therapy of chronic dermal ulcers

Publications (3)

Publication Number Publication Date
JP2004538320A JP2004538320A (ja) 2004-12-24
JP2004538320A5 JP2004538320A5 (enExample) 2006-01-05
JP4192093B2 true JP4192093B2 (ja) 2008-12-03

Family

ID=23192964

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003518575A Expired - Fee Related JP4192093B2 (ja) 2001-07-27 2002-01-16 慢性皮膚潰瘍の治癒を促進する方法

Country Status (11)

Country Link
US (3) US7049294B2 (enExample)
EP (1) EP1414487B1 (enExample)
JP (1) JP4192093B2 (enExample)
CN (1) CN100509055C (enExample)
AT (1) ATE328606T1 (enExample)
AU (1) AU2002236768B2 (enExample)
CA (1) CA2455756C (enExample)
DE (1) DE60212143T2 (enExample)
DK (1) DK1414487T3 (enExample)
ES (1) ES2271216T3 (enExample)
WO (1) WO2003013569A2 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100509055C (zh) * 2001-07-27 2009-07-08 奥索洛吉艾斯有限公司 使用凝血酶衍生的缩氨酸治疗慢性真皮溃疡
EP1539800B1 (en) * 2002-07-02 2007-05-23 Orthologic Corp. Thrombin peptide derivative dimers
AU2003256343B2 (en) * 2002-07-02 2006-12-21 Orthologic Corp. Thrombin peptide derivatives
DE602004005564T2 (de) 2003-12-31 2007-12-13 Orthologic Corp., Tempe Pharmazeutische Zusammensetzung für Thrombinpeptidderivaten
WO2007035406A1 (en) * 2005-09-16 2007-03-29 Orthologic Corp. Antibodies to complementary peptides of thrombin or portions thereof
WO2008124172A1 (en) * 2007-04-10 2008-10-16 The Board Of Regents, The University Of Texas System Combination therapy for chronic dermal ulcers
WO2009120307A2 (en) * 2008-03-26 2009-10-01 Orthologic Corp. Method of treating peripheral arterial disease
EP2268304A2 (en) * 2008-03-26 2011-01-05 Orthologic Corp. Methods for treating acute myocardial infarction
AU2009229395A1 (en) * 2008-03-26 2009-10-01 The Board Of Regents, The University Of Texas System Method of treating degenerative diseases
US20110117075A1 (en) * 2008-03-26 2011-05-19 Orthologic Corp. Thrombin derived peptides for smooth muscle relaxation
GB0916576D0 (en) 2009-09-22 2009-10-28 Malmsten Nils M Polypeptides and uses thereof
EP2538874A4 (en) * 2010-02-24 2017-06-21 Syneron Medical Ltd. A body contouring apparatus
US8806615B2 (en) 2010-11-04 2014-08-12 Mcafee, Inc. System and method for protecting specified data combinations
US10220078B2 (en) 2014-06-11 2019-03-05 The Board Of Regents Of The University Of Texas System Methods of using thrombin derivatives to treat medulloblastoma
CZ308845B6 (cs) * 2019-01-21 2021-07-07 Globetech Innovation S.R.O Farmaceutická směs topicky hojivých peptidových složek pro použití k topické léčbě kožních defektů a/nebo k topickému hojení ran

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5352664A (en) 1986-10-31 1994-10-04 Board Of Regents, The University Of Texas System Thrombin derived polypeptides; compositions and methods for use
AU5638096A (en) 1995-06-07 1996-12-30 Clarion Pharmaceuticals, Inc. Non-biological patch for hemostasis
GB9930768D0 (en) * 1999-12-29 2000-02-16 Pfizer Ltd Composition
IL156233A0 (en) * 2000-12-01 2004-01-04 Response Genetics Inc Method of determining epidermal growth factor receptor and her2-neu gene expression and correlation of levels thereof with survival rates
CN100509055C (zh) * 2001-07-27 2009-07-08 奥索洛吉艾斯有限公司 使用凝血酶衍生的缩氨酸治疗慢性真皮溃疡

Also Published As

Publication number Publication date
WO2003013569A3 (en) 2003-12-11
DE60212143D1 (de) 2006-07-20
ES2271216T3 (es) 2007-04-16
AU2002236768B2 (en) 2006-06-08
EP1414487A2 (en) 2004-05-06
JP2004538320A (ja) 2004-12-24
WO2003013569A2 (en) 2003-02-20
HK1065719A1 (en) 2005-03-24
US7833982B2 (en) 2010-11-16
CN100509055C (zh) 2009-07-08
US7049294B2 (en) 2006-05-23
CN1556711A (zh) 2004-12-22
US20060241049A1 (en) 2006-10-26
CA2455756A1 (en) 2003-02-20
DK1414487T3 (da) 2006-10-09
DE60212143T2 (de) 2007-04-12
US7378500B2 (en) 2008-05-27
ATE328606T1 (de) 2006-06-15
EP1414487B1 (en) 2006-06-07
US20090029923A1 (en) 2009-01-29
CA2455756C (en) 2013-04-02
US20040209819A1 (en) 2004-10-21

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