JP4148662B2 - ヌクレオシド及びオリゴヌクレオチド類縁体を含有する核酸試薬及び医薬 - Google Patents

ヌクレオシド及びオリゴヌクレオチド類縁体を含有する核酸試薬及び医薬 Download PDF

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Publication number
JP4148662B2
JP4148662B2 JP2001241033A JP2001241033A JP4148662B2 JP 4148662 B2 JP4148662 B2 JP 4148662B2 JP 2001241033 A JP2001241033 A JP 2001241033A JP 2001241033 A JP2001241033 A JP 2001241033A JP 4148662 B2 JP4148662 B2 JP 4148662B2
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Japan
Prior art keywords
group
amino
oxo
nucleic acid
dihydropyrimidin
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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JP2001241033A
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English (en)
Japanese (ja)
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JP2002241393A5 (https=
JP2002241393A (ja
Inventor
正勝 金子
浩司 森田
武 今西
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Chemical Corp
Daiichi Sankyo Co Ltd
Original Assignee
Mitsubishi Chemical Foods Corp
Daiichi Sankyo Co Ltd
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Application filed by Mitsubishi Chemical Foods Corp, Daiichi Sankyo Co Ltd filed Critical Mitsubishi Chemical Foods Corp
Priority to JP2001241033A priority Critical patent/JP4148662B2/ja
Publication of JP2002241393A publication Critical patent/JP2002241393A/ja
Priority to US10/430,705 priority patent/US7314923B2/en
Publication of JP2002241393A5 publication Critical patent/JP2002241393A5/ja
Priority to US11/881,775 priority patent/US7816333B2/en
Application granted granted Critical
Publication of JP4148662B2 publication Critical patent/JP4148662B2/ja
Priority to US12/804,500 priority patent/US8957201B2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2001241033A 1999-02-12 2001-08-08 ヌクレオシド及びオリゴヌクレオチド類縁体を含有する核酸試薬及び医薬 Expired - Lifetime JP4148662B2 (ja)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2001241033A JP4148662B2 (ja) 2000-08-10 2001-08-08 ヌクレオシド及びオリゴヌクレオチド類縁体を含有する核酸試薬及び医薬
US10/430,705 US7314923B2 (en) 1999-02-12 2003-05-05 Nucleoside and oligonucleotide analogues
US11/881,775 US7816333B2 (en) 1999-02-12 2007-07-27 Oligonucleotide analogues and methods utilizing the same
US12/804,500 US8957201B2 (en) 1999-02-12 2010-07-22 Oligonucleotide analogues and methods utilizing the same

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2000-242247 2000-08-10
JP2000242247 2000-08-10
JP2001241033A JP4148662B2 (ja) 2000-08-10 2001-08-08 ヌクレオシド及びオリゴヌクレオチド類縁体を含有する核酸試薬及び医薬

Publications (3)

Publication Number Publication Date
JP2002241393A JP2002241393A (ja) 2002-08-28
JP2002241393A5 JP2002241393A5 (https=) 2005-06-23
JP4148662B2 true JP4148662B2 (ja) 2008-09-10

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Family Applications (1)

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JP2001241033A Expired - Lifetime JP4148662B2 (ja) 1999-02-12 2001-08-08 ヌクレオシド及びオリゴヌクレオチド類縁体を含有する核酸試薬及び医薬

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JP (1) JP4148662B2 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050053981A1 (en) * 2003-09-09 2005-03-10 Swayze Eric E. Gapped oligomeric compounds having linked bicyclic sugar moieties at the termini
JP2013256452A (ja) * 2012-06-11 2013-12-26 Kawaken Fine Chem Co Ltd メラニン産生抑制剤とその組成物
US11028390B2 (en) 2017-07-10 2021-06-08 Osaka University Antisense oligonucleotide controlling expression amount of TDP-43 and use thereof
EP3819378A4 (en) 2018-07-04 2022-09-14 Aichi Medical University OLIGONUCLEOTIDES FOR CONTROL OF TAU SPLICING AND THEIR USES
US20240390508A1 (en) 2021-08-21 2024-11-28 Takeda Pharmaceutical Company Limited Human transferrin receptor binding peptide-drug conjugate
CN114437050B (zh) * 2021-12-28 2023-05-23 重庆第二师范学院 一种用于常山酮中间体的脱保护剂及其应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3756313B2 (ja) * 1997-03-07 2006-03-15 武 今西 新規ビシクロヌクレオシド及びオリゴヌクレオチド類縁体
AU9063398A (en) * 1997-09-12 1999-04-05 Exiqon A/S Oligonucleotide analogues
CZ296576B6 (cs) * 1999-02-12 2006-04-12 Sankyo Company Limited Nukleosidový analog a oligonukleotidový analog a farmaceutický prostredek, sonda a primer s jeho obsahem
JP4151751B2 (ja) * 1999-07-22 2008-09-17 第一三共株式会社 新規ビシクロヌクレオシド類縁体
JP2002322192A (ja) * 2000-08-10 2002-11-08 Sankyo Co Ltd ２’−ｏ，４’−ｃ−架橋ヌクレオシドトリリン酸体

Also Published As

Publication number Publication date
JP2002241393A (ja) 2002-08-28

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