JP4024673B2 - 保存安定性を有するイオントフォレシス用リザーバ電極及び該リザーバ電極を具えるイオントフォレシスシステム - Google Patents

保存安定性を有するイオントフォレシス用リザーバ電極及び該リザーバ電極を具えるイオントフォレシスシステム Download PDF

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Publication number
JP4024673B2
JP4024673B2 JP2002506803A JP2002506803A JP4024673B2 JP 4024673 B2 JP4024673 B2 JP 4024673B2 JP 2002506803 A JP2002506803 A JP 2002506803A JP 2002506803 A JP2002506803 A JP 2002506803A JP 4024673 B2 JP4024673 B2 JP 4024673B2
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Japan
Prior art keywords
electrode
reservoir
patient
polymeric material
polymer material
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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JP2002506803A
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English (en)
Japanese (ja)
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JP2004501727A5 (enExample
JP2004501727A (ja
Inventor
ケイ． ジェイン，ウダイ
エヌアールケイ レディ，ビランビ
エム． エリアシュ，ブルース
ジョン キャリー，ケビン
ファレビッチ，ビタリー
コイシュ，プレストン
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Vyteris Inc
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Vyteris Inc
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Publication of JP2004501727A5 publication Critical patent/JP2004501727A5/ja
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Publication of JP4024673B2 publication Critical patent/JP4024673B2/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0448—Drug reservoir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432—Anode and cathode
    • A61N1/0436—Material of the electrode

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Electrotherapy Devices (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
JP2002506803A 2000-06-30 2001-06-29 保存安定性を有するイオントフォレシス用リザーバ電極及び該リザーバ電極を具えるイオントフォレシスシステム Expired - Fee Related JP4024673B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/610,563 US6629968B1 (en) 2000-06-30 2000-06-30 Shelf storage stable iontophoresis reservoir-electrode and iontophoretic system incorporating the reservoir-electrode
PCT/US2001/020886 WO2002002182A2 (en) 2000-06-30 2001-06-29 Shelf storage stable iontophoresis reservoir-electrode and iontophoretic system

Publications (3)

Publication Number Publication Date
JP2004501727A JP2004501727A (ja) 2004-01-22
JP2004501727A5 JP2004501727A5 (enExample) 2005-06-09
JP4024673B2 true JP4024673B2 (ja) 2007-12-19

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ID=24445534

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002506803A Expired - Fee Related JP4024673B2 (ja) 2000-06-30 2001-06-29 保存安定性を有するイオントフォレシス用リザーバ電極及び該リザーバ電極を具えるイオントフォレシスシステム

Country Status (8)

Country Link
US (2) US6629968B1 (enExample)
EP (1) EP1294439B1 (enExample)
JP (1) JP4024673B2 (enExample)
AT (1) ATE369891T1 (enExample)
AU (1) AU2001273104A1 (enExample)
CA (1) CA2413624C (enExample)
DE (1) DE60129965T2 (enExample)
WO (1) WO2002002182A2 (enExample)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6757560B1 (en) * 1999-04-09 2004-06-29 Novosis Pharma Ag Transdermal delivery system (TDS) with electrode network
JP4033382B2 (ja) * 2002-04-08 2008-01-16 久光製薬株式会社 インスリン投与装置
US7776600B2 (en) 2002-04-18 2010-08-17 Carnegie Mellon University Method of manufacturing hydroxyapatite and uses therefor in delivery of nucleic acids
WO2003088925A2 (en) 2002-04-18 2003-10-30 Carnegie Mellon University Method of manufacturing hydroxyapatite and uses therefor in delivery of nucleic acids
JP4089875B2 (ja) * 2002-06-12 2008-05-28 共同印刷株式会社 凹部を含む電極装置
JP3493359B1 (ja) * 2003-03-20 2004-02-03 宣美 辛島 イオン泳動式治療装置
US7917205B2 (en) * 2003-03-20 2011-03-29 Nobuyoshi Karashima Iontophoresis-based medical device
EP1608433B1 (en) * 2003-03-31 2009-03-11 ALZA Corporation Electrotransport device having a reservoir housing having a flexible conductive element
JPWO2005020967A1 (ja) * 2003-08-29 2007-11-01 久光製薬株式会社 電気的薬物移送製剤
US20100016929A1 (en) * 2004-01-22 2010-01-21 Arthur Prochazka Method and system for controlled nerve ablation
EP1706178B1 (en) 2004-01-22 2013-04-24 Rehabtronics Inc. System for routing electrical current to bodily tissues via implanted passive conductors
US20050234516A1 (en) * 2004-02-16 2005-10-20 Gueret Jean-Louis H Treatment kit, composite structure, electric exciter, and cosmetic treatment method
FR2866240B1 (fr) * 2004-02-16 2006-06-23 Oreal Kit de traitement comportant une structure composite a appliquer sur la peau et un excitateur electrique
US20050228335A1 (en) * 2004-04-07 2005-10-13 Reddy Vilambi N Physical, structural, mechanical, electrical and electromechanical features for use in association with electrically assisted delivery devices and systems
US20050228336A1 (en) * 2004-04-07 2005-10-13 Preston Keusch Electrically assisted lidocaine and epinephrine delivery device having extended shelf-stability
WO2006015299A2 (en) * 2004-07-30 2006-02-09 Microchips, Inc. Multi-reservoir device for transdermal drug delivery and sensing
JP4728631B2 (ja) * 2004-11-30 2011-07-20 Ｔｔｉ・エルビュー株式会社 イオントフォレーシス装置
US7590444B2 (en) * 2004-12-09 2009-09-15 Tti Ellebeau, Inc. Iontophoresis device
JP4731931B2 (ja) * 2005-02-03 2011-07-27 Ｔｔｉ・エルビュー株式会社 イオントフォレーシス装置
JP4793806B2 (ja) * 2005-03-22 2011-10-12 Ｔｔｉ・エルビュー株式会社 イオントフォレーシス装置
US8386029B2 (en) 2005-03-31 2013-02-26 Encore Medical Asset Corporation Apparatus for electrotherapy drug delivery with added impurities
US20070027426A1 (en) * 2005-06-24 2007-02-01 Transcutaneous Technologies Inc. Iontophoresis device to deliver active agents to biological interfaces
US8386030B2 (en) 2005-08-08 2013-02-26 Tti Ellebeau, Inc. Iontophoresis device
US8295922B2 (en) 2005-08-08 2012-10-23 Tti Ellebeau, Inc. Iontophoresis device
US20070088331A1 (en) * 2005-08-18 2007-04-19 Transcutaneous Technologies Inc. Method and apparatus for managing active agent usage, and active agent injecting device
KR20080047600A (ko) 2005-09-15 2008-05-29 티티아이 엘뷰 가부시키가이샤 로드형 이온토포레시스 장치
US20070078372A1 (en) * 2005-09-30 2007-04-05 Vyteris, Inc. Iontophoresis Drug Delivery Formulation Providing Acceptable Sensation and Dermal Anesthesia
US20070083147A1 (en) * 2005-09-30 2007-04-12 Transcutaneous Technologies Inc. Iontophoresis apparatus and method to deliver antibiotics to biological interfaces
US7574256B2 (en) 2005-09-30 2009-08-11 Tti Ellebeau, Inc. Iontophoretic device and method of delivery of active agents to biological interface
US20070093788A1 (en) * 2005-09-30 2007-04-26 Darrick Carter Iontophoresis method and apparatus for systemic delivery of active agents
WO2007041158A1 (en) * 2005-09-30 2007-04-12 Vyteris, Inc. Iontophoresis drug delivery device providing acceptable depth and duration of dermal anesthesia
EP1928543A2 (en) * 2005-09-30 2008-06-11 Vyteris, Inc. Pulsatile delivery of gonadotropin-releasing hormone from a pre-loaded integrated electrotransport patch
US20070078434A1 (en) * 2005-09-30 2007-04-05 Vyteris, Inc. Indications For Local Transport of Anaesthetic Agents By Electrotransport Devices
JP5116482B2 (ja) * 2005-11-14 2013-01-09 帝國製薬株式会社 イオントフォレーシス用製剤
WO2007079193A2 (en) 2005-12-30 2007-07-12 Tti Ellebeau, Inc. Iontophoretic systems, devices, and methods of delivery of active agents to biological interface
US8483820B2 (en) * 2006-10-05 2013-07-09 Bioness Inc. System and method for percutaneous delivery of electrical stimulation to a target body tissue
WO2008067409A2 (en) * 2006-11-28 2008-06-05 Polyplus Battery Company Protected lithium electrodes for electro-transport drug delivery
US8062783B2 (en) 2006-12-01 2011-11-22 Tti Ellebeau, Inc. Systems, devices, and methods for powering and/or controlling devices, for instance transdermal delivery devices
WO2008087803A1 (ja) * 2007-01-16 2008-07-24 Hokkaido University 抗酸化成分を封入したイオントフォレーシス用リポソーム製剤
US7844345B2 (en) * 2007-02-08 2010-11-30 Neuropace, Inc. Drug eluting lead systems
US7813811B2 (en) * 2007-02-08 2010-10-12 Neuropace, Inc. Refillable reservoir lead systems
WO2008101171A2 (en) * 2007-02-16 2008-08-21 Thermage, Inc. Temperature sensing apparatus and methods for treatment devices used to deliver high frequency energy to tissue
US8197844B2 (en) 2007-06-08 2012-06-12 Activatek, Inc. Active electrode for transdermal medicament administration
WO2009006349A2 (en) * 2007-06-29 2009-01-08 Polyplus Battery Company Electrotransport devices, methods and drug electrode assemblies
EP2178598A4 (en) * 2007-08-17 2012-08-15 Isis Biopolymer Llc IONTOPHORETIC DRUG DISTRIBUTION SYSTEM
US8738137B2 (en) 2007-08-23 2014-05-27 Bioness Inc. System for transmitting electrical current to a bodily tissue
CA2697381A1 (en) * 2007-08-23 2009-02-26 Bioness, Inc. System for transmitting electrical current to a bodily tissue
US9757554B2 (en) 2007-08-23 2017-09-12 Bioness Inc. System for transmitting electrical current to a bodily tissue
US20090069740A1 (en) * 2007-09-07 2009-03-12 Polyplus Battery Company Protected donor electrodes for electro-transport drug delivery
US8862223B2 (en) 2008-01-18 2014-10-14 Activatek, Inc. Active transdermal medicament patch and circuit board for same
EP2329255A4 (en) 2008-08-27 2014-04-09 Edwards Lifesciences Corp analyte
ES2655714T3 (es) 2009-02-26 2018-02-21 The University Of North Carolina At Chapel Hill Sistema intervencionista de administración de fármacos
SG175341A1 (en) * 2009-05-08 2011-11-28 Isis Biopolymer Inc Iontophoretic device with improved counterelectrode
US20110092881A1 (en) * 2009-05-08 2011-04-21 Isis Biopolymer Inc. Iontophoretic device with contact sensor
WO2011002776A1 (en) * 2009-06-29 2011-01-06 Nitric Biotherapeutics, Inc. Pharmaceutical formulations for iontophoretic delivery of an immunomodulator
JP5463136B2 (ja) 2009-12-22 2014-04-09 帝國製薬株式会社 イオントフォレーシス療法に用いる電極装置
USD678534S1 (en) 2010-07-20 2013-03-19 Iontera, Inc. Iontophoretic device for application to the brow/forehead of a person
CN103269748B (zh) * 2010-12-22 2016-02-17 帝国制药株式会社 用于电离子透入疗法治疗的电极垫
US9610440B2 (en) * 2013-06-10 2017-04-04 Iontera, Inc Systems, devices, and methods for transdermal delivery
GB2524777A (en) * 2014-04-02 2015-10-07 Microarray Ltd Dressing comprising electrodes
CN104287714A (zh) * 2014-11-10 2015-01-21 青岛柏恩鸿泰电子科技有限公司 一种银/氯化银粉末电极
EP3268080A1 (en) * 2015-03-09 2018-01-17 Koninklijke Philips N.V. Iontophoretic device, arrangement and method
CN108883261B (zh) * 2016-01-05 2021-09-28 生物传感器硏究所 用于递送药物的离子电渗设备及其制造方法
US12324792B2 (en) 2020-12-28 2025-06-10 Smith & Nephew, Inc. Methods for making and using pharmaceutical compositions for iontophoresis

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4416274A (en) 1981-02-23 1983-11-22 Motion Control, Inc. Ion mobility limiting iontophoretic bioelectrode
JPS5810066A (ja) * 1981-07-10 1983-01-20 株式会社アドバンス イオントフオレ−ゼ用プラスタ−構造体
CA1262564A (en) * 1983-09-01 1989-10-31 Minoru Sasaki Iontophoresis device
US5135477A (en) 1984-10-29 1992-08-04 Medtronic, Inc. Iontophoretic drug delivery
US4752285B1 (en) 1986-03-19 1995-08-22 Univ Utah Res Found Methods and apparatus for iontophoresis application of medicaments
US5496266A (en) * 1990-04-30 1996-03-05 Alza Corporation Device and method of iontophoretic drug delivery
US4989607A (en) * 1989-03-30 1991-02-05 Preston Keusch Highly conductive non-stringy adhesive hydrophilic gels and medical electrode assemblies manufactured therefrom
US5143071A (en) * 1989-03-30 1992-09-01 Nepera, Inc. Non-stringy adhesive hydrophilic gels
US5328455A (en) * 1989-07-21 1994-07-12 Iomed, Inc. Rehydratable product and method of preparation thereof
US5374241A (en) 1989-07-21 1994-12-20 Iomed, Inc. Electrodes for iontophoresis
US5084008A (en) * 1989-12-22 1992-01-28 Medtronic, Inc. Iontophoresis electrode
US5125894A (en) * 1990-03-30 1992-06-30 Alza Corporation Method and apparatus for controlled environment electrotransport
US5362308A (en) * 1990-09-25 1994-11-08 Rutgers, The State University Of New Jersey Disposable dosage unit for iontophoresis-facilitated transdermal delivery, related devices and processes
MX9101782A (es) 1990-10-29 1992-06-05 Alza Corp Dispositivo de suministro iontoforetico y metodo para hidratar el mismo
US5158537A (en) 1990-10-29 1992-10-27 Alza Corporation Iontophoretic delivery device and method of hydrating same
WO1992015365A1 (en) * 1991-03-11 1992-09-17 Alza Corporation Iontophoretic delivery device and method of making same
US5405317A (en) * 1991-05-03 1995-04-11 Alza Corporation Iontophoretic delivery device
US5464387A (en) * 1991-07-24 1995-11-07 Alza Corporation Transdermal delivery device
US5203768A (en) * 1991-07-24 1993-04-20 Alza Corporation Transdermal delivery device
US5310404A (en) * 1992-06-01 1994-05-10 Alza Corporation Iontophoretic delivery device and method of hydrating same
JP2542792B2 (ja) 1992-11-05 1996-10-09 ベクトン・ディッキンソン・アンド・カンパニー ユ―ザ作動型のイオン導入式装置
US6377847B1 (en) 1993-09-30 2002-04-23 Vyteris, Inc. Iontophoretic drug delivery device and reservoir and method of making same
AU2286995A (en) * 1994-04-08 1995-10-30 Alza Corporation Electrotransport system with ion exchange competitive ion capture
JPH08155041A (ja) * 1994-12-05 1996-06-18 Advance Co Ltd イオントフォレシス用新規高能率電極システム
US5837281A (en) * 1995-03-17 1998-11-17 Takeda Chemical Industries, Ltd. Stabilized interface for iontophoresis
US5990179A (en) * 1995-04-28 1999-11-23 Alza Corporation Composition and method of enhancing electrotransport agent delivery
US5853383A (en) * 1995-05-03 1998-12-29 Alza Corporation Preparation for formulations for electrotransport drug delivery
US5983130A (en) * 1995-06-07 1999-11-09 Alza Corporation Electrotransport agent delivery method and apparatus
CA2208336A1 (en) * 1996-06-20 1997-12-20 Hisamitsu Pharmaceuticals Co., Inc. A device structure for iontophoresis
US6350259B1 (en) * 1996-09-30 2002-02-26 Vyteris, Inc. Selected drug delivery profiles using competing ions
FR2755372B1 (fr) * 1996-11-07 1998-12-24 Elf Aquitaine Dispositif d'ionophorese comportant au moins un ensemble electrode a membrane, pour l'administration transcutanee de principes actifs a un sujet
JP2001505197A (ja) 1996-11-14 2001-04-17 アルザ・コーポレーション リドカイン及びエピネフリンの電気的補助投与のための製剤
US6004577A (en) * 1997-08-12 1999-12-21 Murdock; Thomas O. Enhanced electrotransport of therapeutic agents having polybasic anionic counter ions
US5882677A (en) * 1997-09-30 1999-03-16 Becton Dickinson And Company Iontophoretic patch with hydrogel reservoir
US6295469B1 (en) * 1997-11-14 2001-09-25 Alza Corporation Formulation for electrically assisted delivery of lidocaine and epinephrine
US6496727B1 (en) 2000-05-31 2002-12-17 Becton, Dickinson And Company Medicament-loaded transdermal reservoir and method for its formation

Also Published As

Publication number Publication date
EP1294439A2 (en) 2003-03-26
ATE369891T1 (de) 2007-09-15
DE60129965D1 (de) 2007-09-27
JP2004501727A (ja) 2004-01-22
CA2413624A1 (en) 2002-01-10
EP1294439B1 (en) 2007-08-15
US20020062102A1 (en) 2002-05-23
AU2001273104A1 (en) 2002-01-14
WO2002002182A2 (en) 2002-01-10
US6635045B2 (en) 2003-10-21
CA2413624C (en) 2007-09-18
WO2002002182A3 (en) 2002-06-27
US6629968B1 (en) 2003-10-07
DE60129965T2 (de) 2008-05-15

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