JP3946644B2 - 過敏性の歯を治療するための歯の組成物 - Google Patents
過敏性の歯を治療するための歯の組成物 Download PDFInfo
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- JP3946644B2 JP3946644B2 JP2002586832A JP2002586832A JP3946644B2 JP 3946644 B2 JP3946644 B2 JP 3946644B2 JP 2002586832 A JP2002586832 A JP 2002586832A JP 2002586832 A JP2002586832 A JP 2002586832A JP 3946644 B2 JP3946644 B2 JP 3946644B2
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- JP
- Japan
- Prior art keywords
- dental composition
- composition according
- liposome
- liposomes
- potassium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000003814 drug Substances 0.000 claims description 12
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- YKPUWZUDDOIDPM-SOFGYWHQSA-N capsaicin Chemical compound COC1=CC(CNC(=O)CCCC\C=C\C(C)C)=CC=C1O YKPUWZUDDOIDPM-SOFGYWHQSA-N 0.000 claims description 6
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- 229920005646 polycarboxylate Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 239000004926 polymethyl methacrylate Substances 0.000 description 1
- 239000001205 polyphosphate Substances 0.000 description 1
- 235000011176 polyphosphates Nutrition 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- 229940094025 potassium bicarbonate Drugs 0.000 description 1
- 229960002816 potassium chloride Drugs 0.000 description 1
- 229940093928 potassium nitrate Drugs 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- CVHZOJJKTDOEJC-UHFFFAOYSA-N saccharin Chemical compound C1=CC=C2C(=O)NS(=O)(=O)C2=C1 CVHZOJJKTDOEJC-UHFFFAOYSA-N 0.000 description 1
- 229940081974 saccharin Drugs 0.000 description 1
- 235000019204 saccharin Nutrition 0.000 description 1
- 239000000901 saccharin and its Na,K and Ca salt Substances 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 108700004121 sarkosyl Proteins 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 229910002028 silica xerogel Inorganic materials 0.000 description 1
- RMAQACBXLXPBSY-UHFFFAOYSA-N silicic acid Chemical compound O[Si](O)(O)O RMAQACBXLXPBSY-UHFFFAOYSA-N 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 235000012239 silicon dioxide Nutrition 0.000 description 1
- 229910052709 silver Inorganic materials 0.000 description 1
- 239000004332 silver Substances 0.000 description 1
- 229910001961 silver nitrate Inorganic materials 0.000 description 1
- 239000002356 single layer Substances 0.000 description 1
- 239000000344 soap Substances 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- KSAVQLQVUXSOCR-UHFFFAOYSA-M sodium lauroyl sarcosinate Chemical compound [Na+].CCCCCCCCCCCC(=O)N(C)CC([O-])=O KSAVQLQVUXSOCR-UHFFFAOYSA-M 0.000 description 1
- 229940045885 sodium lauroyl sarcosinate Drugs 0.000 description 1
- 235000019333 sodium laurylsulphate Nutrition 0.000 description 1
- AQMNWCRSESPIJM-UHFFFAOYSA-M sodium metaphosphate Chemical compound [Na+].[O-]P(=O)=O AQMNWCRSESPIJM-UHFFFAOYSA-M 0.000 description 1
- 229960004711 sodium monofluorophosphate Drugs 0.000 description 1
- UGTZMIPZNRIWHX-UHFFFAOYSA-K sodium trimetaphosphate Chemical compound [Na+].[Na+].[Na+].[O-]P1(=O)OP([O-])(=O)OP([O-])(=O)O1 UGTZMIPZNRIWHX-UHFFFAOYSA-K 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 229910001631 strontium chloride Inorganic materials 0.000 description 1
- AHBGXTDRMVNFER-UHFFFAOYSA-L strontium dichloride Chemical compound [Cl-].[Cl-].[Sr+2] AHBGXTDRMVNFER-UHFFFAOYSA-L 0.000 description 1
- 125000001273 sulfonato group Chemical group [O-]S(*)(=O)=O 0.000 description 1
- 230000002459 sustained effect Effects 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 229910001432 tin ion Inorganic materials 0.000 description 1
- HPGGPRDJHPYFRM-UHFFFAOYSA-J tin(iv) chloride Chemical compound Cl[Sn](Cl)(Cl)Cl HPGGPRDJHPYFRM-UHFFFAOYSA-J 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 239000003104 tissue culture media Substances 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- 235000019165 vitamin E Nutrition 0.000 description 1
- 239000011709 vitamin E Substances 0.000 description 1
- 239000000230 xanthan gum Substances 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
- 235000010493 xanthan gum Nutrition 0.000 description 1
- 229940082509 xanthan gum Drugs 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 239000011592 zinc chloride Substances 0.000 description 1
- 235000005074 zinc chloride Nutrition 0.000 description 1
- GFQYVLUOOAAOGM-UHFFFAOYSA-N zirconium(iv) silicate Chemical compound [Zr+4].[O-][Si]([O-])([O-])[O-] GFQYVLUOOAAOGM-UHFFFAOYSA-N 0.000 description 1
- 239000002888 zwitterionic surfactant Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/55—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Cosmetics (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Dental Preparations (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/848,138 US6416745B1 (en) | 2001-05-03 | 2001-05-03 | Dental composition for treating hypersensitive teeth |
| PCT/US2002/013978 WO2002089690A2 (en) | 2001-05-03 | 2002-05-03 | Dental composition for treating hypersensitive teeth |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004525190A JP2004525190A (ja) | 2004-08-19 |
| JP2004525190A5 JP2004525190A5 (enExample) | 2005-12-22 |
| JP3946644B2 true JP3946644B2 (ja) | 2007-07-18 |
Family
ID=25302447
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002586832A Expired - Fee Related JP3946644B2 (ja) | 2001-05-03 | 2002-05-03 | 過敏性の歯を治療するための歯の組成物 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6416745B1 (enExample) |
| EP (1) | EP1390004B1 (enExample) |
| JP (1) | JP3946644B2 (enExample) |
| AT (1) | ATE435053T1 (enExample) |
| AU (1) | AU2002308581A1 (enExample) |
| BR (1) | BR0209368A (enExample) |
| DE (1) | DE60232790D1 (enExample) |
| WO (1) | WO2002089690A2 (enExample) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6416745B1 (en) * | 2001-05-03 | 2002-07-09 | Block Drug Company, Inc. | Dental composition for treating hypersensitive teeth |
| AU2002331481B2 (en) * | 2001-10-03 | 2008-04-24 | Celator Pharmaceuticals, Inc. | Liposome loading with metal ions |
| US6814794B2 (en) * | 2002-11-06 | 2004-11-09 | Ultradent Products, Inc. | Temporary dental cements having reduced tooth sensitivity |
| US20040146831A1 (en) * | 2003-01-23 | 2004-07-29 | Kerrhawe Sa | Unit dose delivery system for dental sensitivity product |
| US20040146464A1 (en) * | 2003-01-23 | 2004-07-29 | Bernstein Joel E. | Compositions and method for daily tooth and gum care |
| JP2006518744A (ja) * | 2003-02-21 | 2006-08-17 | ローディア インコーポレイティド | 抗感受性、抗カリエス、抗しみ、抗歯垢、ウルトラマイルド口腔衛生物質 |
| EP1776083A4 (en) * | 2004-07-02 | 2010-06-02 | Discus Dental Llc | SENSITIVITY-RELATED TOOTH COMPOSITIONS |
| US20080045575A1 (en) * | 2004-12-29 | 2008-02-21 | Van Dyke Thomas E | Delivery of H2 Antagonists |
| US20070258916A1 (en) * | 2006-04-14 | 2007-11-08 | Oregon Health & Science University | Oral compositions for treating tooth hypersensitivity |
| RU2362543C1 (ru) * | 2007-12-12 | 2009-07-27 | Закрытое Акционерное Общество "Лиэп" | Дентальная липосомальная композиция и зубная паста, включающая указанную липосомальную композицию |
| CN101938981A (zh) * | 2008-02-08 | 2011-01-05 | 高露洁-棕榄公司 | 组合物和装置 |
| US20100047742A1 (en) * | 2008-08-25 | 2010-02-25 | Pitcock Jr William Henry | Tubule-blocking silica materials for dentifrices |
| US8905760B2 (en) * | 2008-11-04 | 2014-12-09 | Duane C. Keller | Methods and systems for progressively treating and controlling oral periopathogens causing systemic inflammations |
| US8956161B2 (en) | 2008-11-04 | 2015-02-17 | Duane C Keller | Article and method for controlling oral-originated systemic disease |
| CA2742367A1 (en) * | 2008-11-10 | 2010-05-14 | Colgate-Palmolive Company | Shelf stable capsules |
| TWI469795B (zh) * | 2009-04-01 | 2015-01-21 | Colgate Palmolive Co | 防止過敏和促進再礦化之雙作用牙劑組成物 |
| US20110206749A1 (en) * | 2010-02-19 | 2011-08-25 | J.M. Huber Corporation | Silica materials for reducing oral malador |
| US8658139B1 (en) | 2010-02-27 | 2014-02-25 | Squigle, Inc. | Prevention and treatment of oral diseases |
| US20110236444A1 (en) * | 2010-03-25 | 2011-09-29 | Darsillo Michael S | Antimicrobial Silica Composites |
| US9084902B2 (en) | 2010-06-30 | 2015-07-21 | Mcneil-Ppc, Inc. | Non-alchohol bioactive essential oil mouth rinses |
| US20120003162A1 (en) | 2010-06-30 | 2012-01-05 | Mcneil-Ppc, Inc. | Methods of Preparing Non-Alcohol Bioactive Esential Oil Mouth Rinses |
| US8591229B2 (en) | 2010-12-16 | 2013-11-26 | Duane C. Keller | Devices and methods for creating a positive pressure environment for treatment of oral biofilms associated with periodontal disease |
| BR112016006064B1 (pt) * | 2013-09-19 | 2020-07-07 | Allovate, Llc | kit para terapia da mucosa oral, método para formular uma composição de dentífrico, e, uso de um kit para terapia da mucosa oral |
| EP3217952B9 (en) | 2014-11-11 | 2019-09-04 | Johnson & Johnson Consumer Inc. | Amino acid derivatives and their uses |
| RU2730515C2 (ru) | 2014-11-11 | 2020-08-24 | Джонсон энд Джонсон Консьюмер Инк. | Производные аминокислот и их использование |
| JP6732776B2 (ja) | 2015-02-26 | 2020-07-29 | ジョンソン・アンド・ジョンソン・コンシューマー・インコーポレイテッドＪｏｈｎｓｏｎ ＆ Ｊｏｈｎｓｏｎ Ｃｏｎｓｕｍｅｒ Ｉｎｃ． | 有機酸の組み合わせを含む組成物 |
| US9326925B1 (en) | 2015-02-26 | 2016-05-03 | Johnson & Johnson Consumer Inc. | Compositions comprising combinations of organic acids |
| US9326924B1 (en) | 2015-02-26 | 2016-05-03 | Johnson & Johnson Consumer Inc. | Compositions comprising combinations of organic acids |
| US9974722B2 (en) | 2016-10-20 | 2018-05-22 | Johnson & Johnson Consumer Inc. | Reduced-ethanol mouth rinse formulations |
| US20190175487A1 (en) | 2017-12-07 | 2019-06-13 | Johnson & Johnson Consumer Inc. | Oral Care Compositions |
| US20190175486A1 (en) | 2017-12-07 | 2019-06-13 | Johnson & Johnson Consumer Inc. | Oral Care Compositions |
| WO2020021481A1 (en) | 2018-07-27 | 2020-01-30 | Johnson & Johnson Vision Care, Inc. | Compositions and methods for treating the eye |
| US11166997B2 (en) | 2018-07-27 | 2021-11-09 | Johnson & Johnson Surgical Vision, Inc. | Compositions and methods for treating the eye |
| JP2021532121A (ja) | 2018-07-27 | 2021-11-25 | ジョンソン・アンド・ジョンソン・サージカル・ビジョン・インコーポレイテッド | 眼を治療するための組成物及び方法 |
| CN109010240A (zh) * | 2018-10-25 | 2018-12-18 | 大连丹特生物技术有限公司 | 一种缓解牙齿敏感的药用组合物及其制备方法和应用 |
| US20210023153A1 (en) | 2019-07-23 | 2021-01-28 | Johnson & Johnson Consumer Inc. | Compositions and Methods for Treating the Oral Cavity |
| US11969451B2 (en) | 2019-11-19 | 2024-04-30 | Johnson & Johnson Surgical Vision, Inc. | Compositions and methods for treating the eye |
| CN114469863B (zh) * | 2021-11-26 | 2023-09-26 | 南方医科大学南方医院 | 甾醇脂质体作为牙髓和牙本质药物传递系统的应用 |
| GB202214700D0 (en) * | 2022-10-06 | 2022-11-23 | GlaxoSmithKline Consumer Healthcare UK IP Ltd | Dentifrice composition |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3863006A (en) | 1973-01-29 | 1975-01-28 | Milton Hodosh | Method for desensitizing teeth |
| US4767615A (en) | 1984-05-03 | 1988-08-30 | Technology Unlimited, Inc. | Dental therapy by vesicle delivery |
| US4634589A (en) | 1984-05-18 | 1987-01-06 | Wurttembergische Parfumerie-Fabrik Gmbh | Dentifrice for hypersensitive teeth |
| EP0429442B1 (en) * | 1988-08-22 | 1993-12-29 | DDS Technology, Limited | Dental therapy by vesicle delivery |
| US5104661A (en) * | 1989-08-14 | 1992-04-14 | Technology Unlimited, Inc. | Reverse loading of liposomes |
| AU652778B2 (en) * | 1990-10-15 | 1994-09-08 | Quest International B.V. | Treatment composition |
| GB9022298D0 (en) * | 1990-10-15 | 1990-11-28 | Unilever Plc | Treatment composition |
| FR2676362B3 (fr) * | 1991-05-17 | 1993-08-13 | Oreal | Procede pour accroitre l'activite d'au moins un actif dans une composition a usage cosmetique et/ou dermopharmaceutique et composition pour la mise en óoeuvre dudit procede. |
| US5211939A (en) | 1991-09-13 | 1993-05-18 | Gillette Canada | Method for desensitizing teeth |
| US5270031A (en) | 1991-12-20 | 1993-12-14 | Block Drug Company Inc. | Dentinal desensitizing compositions |
| DE4306475A1 (de) * | 1993-03-02 | 1994-09-08 | Ensenat Pedro Gonzalez | Liposomen, enthaltend Chlorhexidindiacetat oder Chlorhexidindigluconat |
| US5853755A (en) * | 1993-07-28 | 1998-12-29 | Pharmaderm Laboratories Ltd. | Biphasic multilamellar lipid vesicles |
| US5874075A (en) * | 1993-10-06 | 1999-02-23 | Amgen Inc. | Stable protein: phospholipid compositions and methods |
| CA2187355C (en) * | 1994-04-08 | 2009-10-13 | Richard L. Dunn | An adjunctive polymer system for use with medical device |
| FI104881B (fi) | 1994-10-06 | 2000-04-28 | Bioxid Oy | Uusien bioaktiivista piipitoista lasia sisältävien koostumusten valmistusmenetelmä |
| US5589159A (en) | 1995-04-11 | 1996-12-31 | Block Drug Company Inc. | Dispersible particulate system for desensitizing teeth |
| US6261597B1 (en) * | 1995-08-31 | 2001-07-17 | Seymour J. Kurtz | Method for treating periodontal disease |
| US5735942A (en) | 1996-02-07 | 1998-04-07 | Usbiomaterials Corporation | Compositions containing bioactive glass and their use in treating tooth hypersensitivity |
| US6045823A (en) * | 1996-09-19 | 2000-04-04 | Dragoco Gerberding & Co. Ag | Process for producing solid anhydrous composition, and pharmaceutical and cosmetic products comprising same |
| US5935599A (en) * | 1996-10-28 | 1999-08-10 | The Board Of Trustees Of The University Of Illinois | Polymer-associated liposomes for drug delivery and method of manufacturing the same |
| US5922332A (en) * | 1997-09-17 | 1999-07-13 | Fossel; Eric T. | Topical delivery of arginine to overcome pain |
| US6228347B1 (en) * | 1997-12-01 | 2001-05-08 | Thione International, Inc. | Antioxidant gel for gingival conditions |
| WO1999059535A1 (en) * | 1998-05-15 | 1999-11-25 | Unilever Plc | Oral composition comprising capsules |
| DE19922193B4 (de) * | 1999-05-12 | 2004-12-02 | Sonnenberg, Frank, Dipl.-Biol. | Wasserlösliches Konzentrat, bestehend aus ätherischen Ölen mikroverkapselt in einem Liposomensystem, ein Verfahren zu seiner Herstellung und die Verwendung |
| WO2002015809A2 (en) * | 2000-08-21 | 2002-02-28 | Block Drug Company, Inc. | Dental composition for hypersensitive teeth |
| US6416745B1 (en) * | 2001-05-03 | 2002-07-09 | Block Drug Company, Inc. | Dental composition for treating hypersensitive teeth |
-
2001
- 2001-05-03 US US09/848,138 patent/US6416745B1/en not_active Expired - Fee Related
-
2002
- 2002-05-03 BR BR0209368-5A patent/BR0209368A/pt not_active IP Right Cessation
- 2002-05-03 AU AU2002308581A patent/AU2002308581A1/en not_active Abandoned
- 2002-05-03 EP EP02769323A patent/EP1390004B1/en not_active Expired - Lifetime
- 2002-05-03 JP JP2002586832A patent/JP3946644B2/ja not_active Expired - Fee Related
- 2002-05-03 WO PCT/US2002/013978 patent/WO2002089690A2/en not_active Ceased
- 2002-05-03 DE DE60232790T patent/DE60232790D1/de not_active Expired - Lifetime
- 2002-05-03 AT AT02769323T patent/ATE435053T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JP2004525190A (ja) | 2004-08-19 |
| WO2002089690A2 (en) | 2002-11-14 |
| EP1390004A2 (en) | 2004-02-25 |
| BR0209368A (pt) | 2004-06-08 |
| WO2002089690A3 (en) | 2003-11-20 |
| EP1390004B1 (en) | 2009-07-01 |
| ATE435053T1 (de) | 2009-07-15 |
| US6416745B1 (en) | 2002-07-09 |
| DE60232790D1 (de) | 2009-08-13 |
| AU2002308581A1 (en) | 2002-11-18 |
| EP1390004A4 (en) | 2004-08-04 |
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