JP3878208B2 - 芳香族アミド化合物およびそれらのキレート - Google Patents

芳香族アミド化合物およびそれらのキレート Download PDF

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Publication number
JP3878208B2
JP3878208B2 JP52621495A JP52621495A JP3878208B2 JP 3878208 B2 JP3878208 B2 JP 3878208B2 JP 52621495 A JP52621495 A JP 52621495A JP 52621495 A JP52621495 A JP 52621495A JP 3878208 B2 JP3878208 B2 JP 3878208B2
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JP
Japan
Prior art keywords
compound
amino
title
tetraazacyclododecane
oxoethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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JP52621495A
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English (en)
Japanese (ja)
Other versions
JPH08511809A (ja
Inventor
ラマチャドラン エス． ランガナサン
アール． マリネリ，エドムンド
ピレイ，ラドハクリシュナ
エフ． トゥイードル，マイケル
Original Assignee
ブラッコ インターナショナル ベスローテン フェンノートシャップ
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Publication of JPH08511809A publication Critical patent/JPH08511809A/ja
Application granted granted Critical
Publication of JP3878208B2 publication Critical patent/JP3878208B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/12—Macromolecular compounds
    • A61K49/122—Macromolecular compounds dimers of complexes or complex-forming compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
    • A61K49/106—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being cyclic, e.g. DOTA
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/806—Electrical property or magnetic property
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Radiology & Medical Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP52621495A 1994-04-08 1995-04-06 芳香族アミド化合物およびそれらのキレート Expired - Fee Related JP3878208B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US22521094A 1994-04-08 1994-04-08
US08/225,210 1994-04-08
PCT/IB1995/000238 WO1995027705A1 (en) 1994-04-08 1995-04-06 Aromatic amide compounds and metal chelates thereof

Publications (2)

Publication Number Publication Date
JPH08511809A JPH08511809A (ja) 1996-12-10
JP3878208B2 true JP3878208B2 (ja) 2007-02-07

Family

ID=22843981

Family Applications (1)

Application Number Title Priority Date Filing Date
JP52621495A Expired - Fee Related JP3878208B2 (ja) 1994-04-08 1995-04-06 芳香族アミド化合物およびそれらのキレート

Country Status (4)

Country Link
US (1) US5573752A (de)
EP (1) EP0702677A1 (de)
JP (1) JP3878208B2 (de)
WO (1) WO1995027705A1 (de)

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US6746662B1 (en) * 1999-02-09 2004-06-08 Board Of Regents The University Of Texas System pH sensitive MRI contrast agents
WO2000047111A1 (en) * 1999-02-09 2000-08-17 Board Of Regents The University Of Texas System Ph sensitive mri contrast agents
EP1154990B1 (de) * 1999-02-18 2004-12-22 The Regents Of The University Of California Phthalamid-lanthanid komplexe zur verwendung als lumineszenzmarker
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AR047692A1 (es) * 2003-07-10 2006-02-08 Epix Medical Inc Imagenes de blancos estacionarios
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WO2005122891A1 (en) 2004-06-09 2005-12-29 Kereos, Inc. Lipophilic derivatives of chelate monoamides
WO2006039505A2 (en) 2004-09-30 2006-04-13 Molecular Devices Corporation Luminescent lanthanide complexes
DE602005010747D1 (de) 2005-01-13 2008-12-11 Cinv Ag Kohlenstoffnanopartikel enthaltende verbundwerkstoffe
GB0502482D0 (en) * 2005-02-07 2005-03-16 Glaxo Group Ltd Novel compounds
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KR101502180B1 (ko) * 2006-08-30 2015-03-12 지이 헬스케어 에이에스 동적 핵 분극화 방법 및 이러한 방법에서 사용되는 화합물 및 조성물
CA2675121A1 (en) * 2007-01-19 2008-07-24 Cinvention Ag Porous, non-degradable implant made by powder molding
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US9057016B2 (en) 2011-08-29 2015-06-16 Ticona Llc Melt polymerization of low melt viscosity liquid crystalline polymers
JP2014525501A (ja) 2011-08-29 2014-09-29 ティコナ・エルエルシー 高流動性液晶ポリマー組成物
TW201319023A (zh) 2011-08-29 2013-05-16 Ticona Llc 具改良低剪切黏度之熱向性液晶聚合物
US8906258B2 (en) 2011-08-29 2014-12-09 Ticona Llc Heat-resistant liquid crystalline polymer composition having a low melting temperature
CN103764794B (zh) 2011-08-29 2016-05-18 提克纳有限责任公司 高流动液晶聚合物组合物
JP2014529627A (ja) 2011-08-29 2014-11-13 ティコナ・エルエルシー 芳香族アミド化合物
US8669341B2 (en) 2011-08-29 2014-03-11 Ticona Llc Solid-state polymerization of a liquid crystalline polymer
US9045685B2 (en) 2011-08-29 2015-06-02 Ticona Llc Cast molded parts formed from a liquid crystalline polymer
US8852730B2 (en) 2011-08-29 2014-10-07 Ticona Llc Melt-extruded substrate for use in thermoformed articles
WO2014130275A2 (en) 2013-02-22 2014-08-28 Ticona Llc High performance polymer composition with improved flow properties
CN105358657A (zh) 2013-06-07 2016-02-24 提克纳有限责任公司 高强度热致液晶聚合物

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Also Published As

Publication number Publication date
US5573752A (en) 1996-11-12
EP0702677A1 (de) 1996-03-27
WO1995027705A1 (en) 1995-10-19
JPH08511809A (ja) 1996-12-10

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