JP3868210B2 - Ｎ−アシル−３，４−デヒドロプロリンおよびｎ−アシル−３，４−デヒドロピペリジン−２−カルボン酸誘導体の製法 - Google Patents

Ｎ−アシル−３，４−デヒドロプロリンおよびｎ−アシル−３，４−デヒドロピペリジン−２−カルボン酸誘導体の製法 Download PDF

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Publication number
JP3868210B2
JP3868210B2 JP2000607987A JP2000607987A JP3868210B2 JP 3868210 B2 JP3868210 B2 JP 3868210B2 JP 2000607987 A JP2000607987 A JP 2000607987A JP 2000607987 A JP2000607987 A JP 2000607987A JP 3868210 B2 JP3868210 B2 JP 3868210B2
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Japan
Prior art keywords
dehydropiperidine
acyl
dehydroproline
alkyl
general formula
Prior art date
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Expired - Fee Related
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JP2000607987A
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English (en)
Japanese (ja)
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JP2002540190A (ja
JP2002540190A5 (https=
Inventor
シェーファー ベルント
ヘルムヒェン ギュンター
カッツマイヤー ウーリ
シュライヒ ジモーネ
シュター ヘルムト
ヴォルファート フォルカー
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BASF SE
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BASF SE
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Publication date
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Publication of JP2002540190A5 publication Critical patent/JP2002540190A5/ja
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Publication of JP3868210B2 publication Critical patent/JP3868210B2/ja
Anticipated expiration legal-status Critical
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/20—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2000607987A 1999-03-26 2000-03-17 Ｎ−アシル−３，４−デヒドロプロリンおよびｎ−アシル−３，４−デヒドロピペリジン−２−カルボン酸誘導体の製法 Expired - Fee Related JP3868210B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19913699.8 1999-03-26
DE19913699A DE19913699A1 (de) 1999-03-26 1999-03-26 Verfahren zur Herstellung von 3,4-Dihydroprolinen und 3,4-Dehydropiperidinen
PCT/EP2000/002377 WO2000058284A1 (de) 1999-03-26 2000-03-17 Verfahren zur herstellung von n-acyl-3,4 - dehydroprolin und n-acyl-3,4 - dehydropiperidin-2-carbonsäure derivaten

Publications (3)

Publication Number Publication Date
JP2002540190A JP2002540190A (ja) 2002-11-26
JP2002540190A5 JP2002540190A5 (https=) 2006-03-30
JP3868210B2 true JP3868210B2 (ja) 2007-01-17

Family

ID=7902464

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000607987A Expired - Fee Related JP3868210B2 (ja) 1999-03-26 2000-03-17 Ｎ−アシル−３，４−デヒドロプロリンおよびｎ−アシル−３，４−デヒドロピペリジン−２−カルボン酸誘導体の製法

Country Status (22)

Country Link
US (1) US6579971B1 (https=)
EP (1) EP1165509B1 (https=)
JP (1) JP3868210B2 (https=)
KR (1) KR20010104730A (https=)
CN (1) CN1345310A (https=)
AT (1) ATE278665T1 (https=)
AU (1) AU3962500A (https=)
BR (1) BR0009330A (https=)
CA (1) CA2368479C (https=)
CZ (1) CZ20013456A3 (https=)
DE (2) DE19913699A1 (https=)
ES (1) ES2230088T3 (https=)
HK (1) HK1045156A1 (https=)
HU (1) HUP0200420A2 (https=)
IL (1) IL145525A0 (https=)
MX (1) MXPA01009679A (https=)
NO (1) NO20014645D0 (https=)
RU (1) RU2001129097A (https=)
TR (1) TR200102747T2 (https=)
TW (1) TWI276626B (https=)
WO (1) WO2000058284A1 (https=)
ZA (1) ZA200107629B (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100396666C (zh) * 2005-12-14 2008-06-25 郑州大学 （4s）-1-叔丁氧羰基-4-氨基-l-脯氨酸乙酯及其合成工艺

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4291040A (en) * 1979-10-22 1981-09-22 E. R. Squibb & Sons, Inc. Mercaptoacyl derivatives of 4-disubstituted prolines and 4-substituted dehydroprolines
US5580575A (en) 1989-12-22 1996-12-03 Imarx Pharmaceutical Corp. Therapeutic drug delivery systems
ES2152990T3 (es) 1993-09-09 2001-02-16 Schering Ag Principios activos y microparticulas que contienen gases.
DE19630082A1 (de) * 1996-07-26 1998-01-29 Basf Ag Verfahren zur Herstellung von 3-Pyrrolin-2-carbonsäure-Derivaten
US6090800A (en) 1997-05-06 2000-07-18 Imarx Pharmaceutical Corp. Lipid soluble steroid prodrugs
DE19723473A1 (de) * 1997-06-04 1998-12-10 Basf Ag Verfahren zur Herstellung von chiralen 3,4-Didehydroprolinen
ES2244169T3 (es) 1998-02-09 2005-12-01 Bracco International B.V. Suministro direccionado de medios biologicamente activos.

Also Published As

Publication number Publication date
WO2000058284A1 (de) 2000-10-05
CZ20013456A3 (cs) 2002-05-15
AU3962500A (en) 2000-10-16
IL145525A0 (en) 2002-06-30
NO20014645L (no) 2001-09-25
EP1165509B1 (de) 2004-10-06
DE19913699A1 (de) 2000-09-28
US6579971B1 (en) 2003-06-17
CA2368479C (en) 2005-03-01
HUP0200420A2 (hu) 2002-05-29
BR0009330A (pt) 2002-01-08
KR20010104730A (ko) 2001-11-26
HK1045156A1 (zh) 2002-11-15
ES2230088T3 (es) 2005-05-01
TR200102747T2 (tr) 2002-02-21
CN1345310A (zh) 2002-04-17
MXPA01009679A (es) 2002-03-14
JP2002540190A (ja) 2002-11-26
ZA200107629B (en) 2002-09-17
EP1165509A1 (de) 2002-01-02
ATE278665T1 (de) 2004-10-15
TWI276626B (en) 2007-03-21
RU2001129097A (ru) 2004-03-20
DE50008117D1 (de) 2004-11-11
CA2368479A1 (en) 2000-10-05
NO20014645D0 (no) 2001-09-25

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