JP3842784B2 - 磁気吸引性の粒子を分離するためのシステム - Google Patents

磁気吸引性の粒子を分離するためのシステム Download PDF

Info

Publication number
JP3842784B2
JP3842784B2 JP2003515326A JP2003515326A JP3842784B2 JP 3842784 B2 JP3842784 B2 JP 3842784B2 JP 2003515326 A JP2003515326 A JP 2003515326A JP 2003515326 A JP2003515326 A JP 2003515326A JP 3842784 B2 JP3842784 B2 JP 3842784B2
Authority
JP
Japan
Prior art keywords
container
magnet
particles
liquid
magnets
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2003515326A
Other languages
English (en)
Japanese (ja)
Other versions
JP2004535591A5 (enExample
JP2004535591A (ja
Inventor
ミューラー，ハンス−ユールゲン
ホルツァー，アンドレアス
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of JP2004535591A publication Critical patent/JP2004535591A/ja
Publication of JP2004535591A5 publication Critical patent/JP2004535591A5/ja
Application granted granted Critical
Publication of JP3842784B2 publication Critical patent/JP3842784B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Images

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/02—Magnetic separation acting directly on the substance being separated
    • B03C1/28—Magnetic plugs and dipsticks
    • B03C1/288—Magnetic plugs and dipsticks disposed at the outer circumference of a recipient
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/02—Magnetic separation acting directly on the substance being separated
    • B03C1/035—Open gradient magnetic separators, i.e. separators in which the gap is unobstructed, characterised by the configuration of the gap
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00—Details of magnetic or electrostatic separation
    • B03C2201/26—Details of magnetic or electrostatic separation for use in medical or biological applications
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation

Landscapes

  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
JP2003515326A 2001-07-25 2002-07-23 磁気吸引性の粒子を分離するためのシステム Expired - Fee Related JP3842784B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10136060A DE10136060A1 (de) 2001-07-25 2001-07-25 System zur Separation von magnetisch anziehbaren Partikeln
PCT/EP2002/008174 WO2003009943A1 (de) 2001-07-25 2002-07-23 System zur separation von magnetisch anziehbaren partikeln

Publications (3)

Publication Number Publication Date
JP2004535591A JP2004535591A (ja) 2004-11-25
JP2004535591A5 JP2004535591A5 (enExample) 2005-10-27
JP3842784B2 true JP3842784B2 (ja) 2006-11-08

Family

ID=7692933

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003515326A Expired - Fee Related JP3842784B2 (ja) 2001-07-25 2002-07-23 磁気吸引性の粒子を分離するためのシステム

Country Status (8)

Country Link
US (1) US7326350B2 (enExample)
EP (1) EP1420888B1 (enExample)
JP (1) JP3842784B2 (enExample)
AT (1) ATE297255T1 (enExample)
CA (1) CA2453110C (enExample)
DE (2) DE10136060A1 (enExample)
ES (1) ES2242877T3 (enExample)
WO (1) WO2003009943A1 (enExample)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003226075B2 (en) 2002-04-12 2008-09-25 Instrumentation Laboratory Company Immunoassay probe
US8211386B2 (en) 2004-06-08 2012-07-03 Biokit, S.A. Tapered cuvette and method of collecting magnetic particles
US7535329B2 (en) * 2005-04-14 2009-05-19 Makrochem, Ltd. Permanent magnet structure with axial access for spectroscopy applications
US7867765B2 (en) 2005-12-28 2011-01-11 The General Hospital Corporation Blood cell sorting methods and systems
US8268116B2 (en) * 2007-06-14 2012-09-18 Lam Research Corporation Methods of and apparatus for protecting a region of process exclusion adjacent to a region of process performance in a process chamber
US8795609B2 (en) * 2007-02-08 2014-08-05 Biokit, S.A. Magnetic particle washing station
JP2008209330A (ja) * 2007-02-28 2008-09-11 Hitachi High-Technologies Corp 磁気分離器およびそれを用いた分析装置
US9199247B2 (en) * 2007-05-29 2015-12-01 Invitrogen Dynal As Magnetic separation rack
GB0724404D0 (en) * 2007-05-29 2008-01-30 Invitrogen Dynal As A sample vessel retaining portion
JP4586054B2 (ja) * 2007-08-31 2010-11-24 株式会社日立ハイテクノロジーズ 自動分析装置
US8723113B2 (en) * 2008-05-30 2014-05-13 The State of Oregon Acting by and through the State Board of Higher Education of behalf of Oregon State University Radio-frequency-free hybrid electrostatic/magnetostatic cell for transporting, trapping, and dissociating ions in mass spectrometers
EP2306959A2 (en) * 2008-07-11 2011-04-13 The General Hospital Corporation Magnetic apparatus for blood separation
EP2208531A1 (en) * 2008-12-30 2010-07-21 Atonomics A/S Distribution of particles in capillary channel by application of magnetic field
EP2246349A1 (en) 2009-04-20 2010-11-03 BKG Pharma ApS Treatment of infectious diseases
US20120262260A1 (en) * 2011-04-18 2012-10-18 Exact Sciences Corporation Magnetic microparticle localization device
JP6297546B2 (ja) * 2012-06-29 2018-03-20 コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． 結合磁性粒子及び未結合磁性粒子の処理
EP2883237B1 (en) 2012-08-16 2020-11-25 The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Electromagnetostatic electron-induced dissociation cell
US9803787B2 (en) * 2012-09-14 2017-10-31 The United States Of America, As Represented By The Secretary Of The Navy Magnetically attracted fluid transfer system
KR101367122B1 (ko) * 2012-09-20 2014-02-26 한국원자력연구원 영구자석을 이용한 자기 장치
US20150233932A1 (en) * 2013-02-19 2015-08-20 Ching-Ping Tseng Methods, Systems, and Compositions for Enrichment of Rare Cells
US9387486B2 (en) * 2014-09-30 2016-07-12 Ut-Battelle, Llc High-gradient permanent magnet apparatus and its use in particle collection
JP6472973B2 (ja) * 2014-10-24 2019-02-20 日本電子株式会社 自動分析装置及び分離洗浄方法
CZ306187B6 (cs) * 2015-02-26 2016-09-14 Univerzita PalackĂ©ho v Olomouci Zařízení pro magnetickou separaci feromagnetických částic, sada pro magnetickou separaci částic, způsob separace magnetických částic z roztoku a použití zařízení nebo sady pro magnetickou separaci částic
CN108474024B (zh) * 2016-01-05 2022-08-02 豪夫迈·罗氏有限公司 磁性玻璃颗粒对核酸的连续捕获
US11125365B2 (en) 2018-02-28 2021-09-21 Kohler Co. Magnetic joint
US11408543B2 (en) 2018-02-28 2022-08-09 Kohler Co. Articulating faucet
US10890277B2 (en) * 2018-02-28 2021-01-12 Kohler Co. Articulating faucet with progressive magnetic joint
US11214946B2 (en) 2018-06-04 2022-01-04 Kohler Co. Articulating faucet
US11242675B2 (en) 2018-06-04 2022-02-08 Kohler Co. Articulating faucet
EP4614158A1 (en) * 2022-10-31 2025-09-10 FUJIFILM Corporation Magnetic collecting unit, and testing device
EP4614157A1 (en) * 2022-10-31 2025-09-10 FUJIFILM Corporation Magnetic collecting unit and test device

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6253714A (ja) * 1985-08-30 1987-03-09 Kamata Bio Eng Kk 流体の磁化浄化装置
JPS6295371A (ja) 1985-10-22 1987-05-01 Agency Of Ind Science & Technol 粉末状吸湿架橋性ホツトメルト接着剤の製造方法
EP0479448A3 (en) 1990-10-02 1992-12-23 Beckman Instruments, Inc. Magnetic separation device
US5897783A (en) 1992-09-24 1999-04-27 Amersham International Plc Magnetic separation method
US5599501A (en) 1994-11-10 1997-02-04 Ciba Corning Diagnostics Corp. Incubation chamber
EP0810905B1 (en) * 1995-02-21 1998-11-04 Iqbal W. Dr. Siddiqi Apparatus and method for mixing and separation employing magnetic particles
US5888835A (en) 1996-05-10 1999-03-30 Chiron Diagnostics Corporation Method and apparatus for wash, resuspension, recollection and localization of magnetizable particles in assays using magnetic separation technology
US6451207B1 (en) * 1997-06-04 2002-09-17 Dexter Magnetic Technologies, Inc. Magnetic cell separation device
AU1778701A (en) * 1999-11-17 2001-05-30 University Of Virginia Patent Foundation Sperm cell selection system

Also Published As

Publication number Publication date
WO2003009943A8 (de) 2005-03-03
ATE297255T1 (de) 2005-06-15
DE10136060A1 (de) 2003-02-13
ES2242877T3 (es) 2005-11-16
CA2453110C (en) 2010-02-09
JP2004535591A (ja) 2004-11-25
EP1420888B1 (de) 2005-06-08
DE50203361D1 (de) 2005-07-14
US7326350B2 (en) 2008-02-05
US20040265903A1 (en) 2004-12-30
EP1420888A1 (de) 2004-05-26
WO2003009943A1 (de) 2003-02-06
CA2453110A1 (en) 2003-02-06

Similar Documents

Publication Publication Date Title
JP3842784B2 (ja) 磁気吸引性の粒子を分離するためのシステム
US6361749B1 (en) Apparatus and methods for magnetic separation
Choi et al. An on-chip magnetic bead separator using spiral electromagnets with semi-encapsulated permalloy
US8361316B2 (en) Device for mixing and separation of magnetic particles
EP0810905B1 (en) Apparatus and method for mixing and separation employing magnetic particles
EP2160248B1 (en) Magnetic separating device and method
US6500343B2 (en) Method for mixing and separation employing magnetic particles
JP3085709B2 (ja) 磁気分離機、磁気分離方法、リガンド測定方法ならびに分離方法
CN101772379B (zh) 用于使颗粒悬浮或再悬浮在溶液中的方法以及适合的设备
US10293344B2 (en) Sample holder with magnetic base and magnetisable body
JP2004535591A5 (enExample)
JP4065401B2 (ja) 分散された又は溶解された物質を分離する方法及びマグネットセパレータ
US20150153259A1 (en) Multi-parameter high gradient magnetic separator and methods of use thereof
US20100300978A1 (en) Device, system and method for washing and isolating magnetic particles in a continous fluid flow
JP2003519008A (ja) 磁性粒子を利用した混合／分離装置及び方法
JP5336495B2 (ja) 磁性粒子を用いて液体を処理する装置及び方法
US5835329A (en) Apparatus for agitation separation of magnetic particles
WO2004011146A1 (en) A device and method for manipulating magnetic particles
WO1999061919A2 (en) Magnetic particle suspending device, apparatus and methods for using same
US20240011014A1 (en) In-tip magnetic-based magnetic bead processing

Legal Events

Date Code Title Description
TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20060718

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20060810

R150 Certificate of patent or registration of utility model

Free format text: JAPANESE INTERMEDIATE CODE: R150

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20090818

Year of fee payment: 3

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20100818

Year of fee payment: 4

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20110818

Year of fee payment: 5

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20110818

Year of fee payment: 5

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20120818

Year of fee payment: 6

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20120818

Year of fee payment: 6

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20130818

Year of fee payment: 7

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

LAPS Cancellation because of no payment of annual fees