JP3842783B2 - 磁気共鳴装置 - Google Patents
磁気共鳴装置 Download PDFInfo
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- 206010020843 Hyperthermia Diseases 0.000 claims description 43
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N2/00—Magnetotherapy
- A61N2/02—Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/40—Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals
- A61N1/403—Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals for thermotherapy, e.g. hyperthermia
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/48—NMR imaging systems
- G01R33/4804—Spatially selective measurement of temperature or pH
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/48—NMR imaging systems
- G01R33/4808—Multimodal MR, e.g. MR combined with positron emission tomography [PET], MR combined with ultrasound or MR combined with computed tomography [CT]
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/48—NMR imaging systems
- G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
- G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
- G01R33/561—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution by reduction of the scanning time, i.e. fast acquiring systems, e.g. using echo-planar pulse sequences
- G01R33/5611—Parallel magnetic resonance imaging, e.g. sensitivity encoding [SENSE], simultaneous acquisition of spatial harmonics [SMASH], unaliasing by Fourier encoding of the overlaps using the temporal dimension [UNFOLD], k-t-broad-use linear acquisition speed-up technique [k-t-BLAST], k-t-SENSE
- G01R33/5612—Parallel RF transmission, i.e. RF pulse transmission using a plurality of independent transmission channels
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- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Radiology & Medical Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
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- Physics & Mathematics (AREA)
- High Energy & Nuclear Physics (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Electrotherapy Devices (AREA)
Description
高周波送信・受信ユニットは検査空間の周りにアレイ状に配置された複数のアンテナを有し、各アンテナには専用の送信チャネルおよび専用の受信チャネルが存在し、
制御ユニットは、制御ユニットが各アンテナごとにアンテナによって受信された磁気共鳴信号の振幅および位相を求め、ハイパーサーミア治療のために検査空間内に集束された高周波電磁場を発生させるために、予め定め得る位相および振幅の高周波放射の放出のためにアンテナを互いに独立に制御することができるように構成されていることによって解決される。
なお、磁気共鳴装置の作動方法は、本発明によれば、患者の限定された身体範囲のハイパーサーミア治療のために、傾斜磁場コイルおよび高周波送信・受信ユニットが、まず第1の磁気共鳴測定の形で位置依存性の振幅測定および位相測定を行なうための同調シーケンスにより制御され、各アンテナごとに、患者の限定された身体範囲から受信された磁気共鳴信号の振幅および位相が測定され、それから各アンテナごとに、限定された身体範囲への高周波放射の集束に必要な振幅および位相が求められ、引続いて、ハイパーサーミア治療のために限定された身体範囲に集束された高周波電磁場が発生されるように、個々のアンテナが高周波放射の放出のためにアンテナごとに求められた振幅および位相で互いに独立に制御される。
磁気共鳴装置の作動方法においては、次のような実施態様が考えられる。
第1の磁気共鳴測定を行なうための同調シーケンスとしてFID制御シーケンスが使用される。
限定された身体範囲の温度測定を第2の磁気共鳴測定を介して行なうために、ハイパーサーミア治療中の周波ビーム放出の制御が繰り返して短時間だけ中断される。温度測定のための第2の磁気共鳴測定における磁気共鳴信号は磁気共鳴装置に接続された表面コイルを介して検出される。
アンテナは、磁気共鳴測定を行なうためとハイパーサーミア治療のために、同じHF周波数にて制御される。
集束に必要な振幅および位相をその都度新たに求めるために1つ又は複数の他の磁気共鳴測定を行ない、引続いてハイパーサーミア治療を続行するためにアンテナごとに新たに求めた振幅および位相でアンテナを互いに独立に制御するために、ハイパーサーミア治療中の高周波放射の放出の制御が1回又は複数回短時間だけ中断される。
図1は磁気共鳴装置の極めて簡単化した図を示し、
図2は本発明による磁気共鳴装置の高周波送信・受信ユニットの構成例を概略的に示し、
図3は患者の腫瘍の身体範囲において個々のアンテナによって発生させられた高周波電磁場の重畳を具体的に説明するための略図を示し、
図4は振幅および位相の正しい高周波信号の発生のためのNCOの作動例を示し、
図5は同時の温度測定をともなうハイパーサーミア治療のための模範的なシーケンスを示す。
2 送信チャネル
3 受信チャネル
4 表面コイル
5 受信チャネル
6 メモリ
7 変調器
8 ディジタル・アナログ変換器
9 電力増幅器
10 送信−受信切換器
11 同調回路
12 前置増幅器
13 アナログ・ディジタル変換器
14 復調器(NCO)
15 評価コンピュータ
16 身体範囲
17 患者
20 送出パルス(加熱シーケンス)
21 高周波パルス列
22 受信時間
23 基本磁場磁石
24 傾斜磁場コイル
25 高周波送信・受信ユニット
26 制御ユニット
27 検査空間
Claims (7)
- 基本磁場磁石(23)と、傾斜磁場コイル(24)と、高周波送信・受信ユニット(25)と、磁気共鳴測定を実施するために傾斜磁場コイル(24)および高周波送信・受信ユニット(25)を制御する制御ユニット(26)とを備えた磁気共鳴装置において、
高周波送信・受信ユニット(25)は検査空間(27)の周りにアレイ状に配置された複数のアンテナ(1)を有し、各アンテナ(1)には専用の送信チャネル(2)および専用の受信チャネル(3)が存在し、
制御ユニット(26)は、制御ユニット(26)が各アンテナ(1)ごとにアンテナ(1)によって受信された磁気共鳴信号の振幅および位相を求め、ハイパーサーミア治療のために検査空間(27)内に集束された高周波電磁場を発生させるために、予め定め得る位相および振幅の高周波放射の放出のためにアンテナ(1)を互いに独立に制御することができるように構成されていることを特徴とする磁気共鳴装置。 - 各送信チャネル(2)は電力増幅器(9)および変調器(7)を有することを特徴とする請求項1記載の磁気共鳴装置。
- アンテナ(1)は共鳴棒として形成されていることを特徴とする請求項1または2記載の磁気共鳴装置。
- 制御ユニット(26)は、集束された高周波電磁場を当てられた身体範囲(16)の温度を求めるための磁気共鳴測定を行なうための高周波送信ユニット(25)および傾斜磁場コイル(24)を制御するために、ハイパーサーミア治療中に集束された高周波電磁場の発生を予め定め得る時点で短時間だけ中断するように構成されていることを特徴とする請求項1乃至3の1つに記載の磁気共鳴装置。
- 各送信チャネル(2)は検査範囲(27)におけるインピーダンス状態に線路インピーダンスを整合させるための整合回路(11)と接続されていることを特徴とする請求項1乃至4の1つに記載の磁気共鳴装置。
- アンテナ(1)は検査空間(27)の周囲に円筒状装置を形成していることを特徴とする請求項1乃至5の1つに記載の磁気共鳴装置。
- 基本磁場磁石(23)は少なくとも2Tの磁場強さを発生するように設計されていることを特徴とする請求項1乃至6の1つに記載の磁気共鳴装置。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10130619 | 2001-06-26 | ||
PCT/DE2002/002215 WO2003002199A2 (de) | 2001-06-26 | 2002-06-18 | Magnetresonanzanlage und verfahren zum betrieb |
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JP2004530518A JP2004530518A (ja) | 2004-10-07 |
JP3842783B2 true JP3842783B2 (ja) | 2006-11-08 |
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JP2003508435A Expired - Fee Related JP3842783B2 (ja) | 2001-06-26 | 2002-06-18 | 磁気共鳴装置 |
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Country | Link |
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US (1) | US7123010B2 (ja) |
EP (1) | EP1399219A2 (ja) |
JP (1) | JP3842783B2 (ja) |
KR (1) | KR20040015257A (ja) |
CN (1) | CN1283209C (ja) |
WO (1) | WO2003002199A2 (ja) |
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KR102531234B1 (ko) * | 2019-12-02 | 2023-05-11 | 고려대학교 세종산학협력단 | 자기공명영상시스템의 내부에서 사용될 수 있는 고주파 온열 조사 장치 |
EP3839540A1 (de) * | 2019-12-20 | 2021-06-23 | Siemens Healthcare GmbH | Betreiben eines mr-systems sowie mr-system |
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- 2002-06-18 KR KR10-2003-7015826A patent/KR20040015257A/ko not_active Application Discontinuation
- 2002-06-18 CN CNB028037251A patent/CN1283209C/zh not_active Expired - Fee Related
- 2002-06-18 WO PCT/DE2002/002215 patent/WO2003002199A2/de active Application Filing
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WO2003002199A3 (de) | 2003-04-10 |
US7123010B2 (en) | 2006-10-17 |
KR20040015257A (ko) | 2004-02-18 |
JP2004530518A (ja) | 2004-10-07 |
EP1399219A2 (de) | 2004-03-24 |
US20040199070A1 (en) | 2004-10-07 |
CN1283209C (zh) | 2006-11-08 |
CN1533291A (zh) | 2004-09-29 |
WO2003002199A2 (de) | 2003-01-09 |
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