GB2319340A - Insertable MRI RF coil with ultrasound, RF, or laser targeting transducers - Google Patents

Insertable MRI RF coil with ultrasound, RF, or laser targeting transducers Download PDF

Info

Publication number
GB2319340A
GB2319340A GB9704883A GB9704883A GB2319340A GB 2319340 A GB2319340 A GB 2319340A GB 9704883 A GB9704883 A GB 9704883A GB 9704883 A GB9704883 A GB 9704883A GB 2319340 A GB2319340 A GB 2319340A
Authority
GB
United Kingdom
Prior art keywords
coil
transducers
ultrasound
transducer
former
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GB9704883A
Other versions
GB9704883D0 (en
Inventor
Ian Robert Young
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BAE Systems Electronics Ltd
Original Assignee
GEC Marconi Ltd
Marconi Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GEC Marconi Ltd, Marconi Co Ltd filed Critical GEC Marconi Ltd
Publication of GB9704883D0 publication Critical patent/GB9704883D0/en
Priority to EP97308882A priority Critical patent/EP0841576B1/en
Priority to DE69728490T priority patent/DE69728490T2/en
Priority to US08/966,823 priority patent/US6320379B1/en
Priority to JP9310503A priority patent/JPH10151122A/en
Publication of GB2319340A publication Critical patent/GB2319340A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
    • G01R33/32—Excitation or detection systems, e.g. using radio frequency signals
    • G01R33/34—Constructional details, e.g. resonators, specially adapted to MR
    • G01R33/34084—Constructional details, e.g. resonators, specially adapted to MR implantable coils or coils being geometrically adaptable to the sample, e.g. flexible coils or coils comprising mutually movable parts
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/4808—Multimodal MR, e.g. MR combined with positron emission tomography [PET], MR combined with ultrasound or MR combined with computed tomography [CT]
    • G01R33/4814—MR combined with ultrasound
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
    • G01R33/285—Invasive instruments, e.g. catheters or biopsy needles, specially adapted for tracking, guiding or visualization by NMR
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/4804—Spatially selective measurement of temperature or pH

Landscapes

  • Physics & Mathematics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • General Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Theoretical Computer Science (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Thermotherapy And Cooling Therapy Devices (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)

Abstract

An insertable MRI RF coil is carried on a former which also carries at least one transducer by which focused ultrasound, hyperthermia-inducing RF radiation, or laser radiation may be controlled both in direction and strength. The transducers may be PLZT sensors (for ultrasound) or dipoles (for RF hyperthermia).

Description

Nuclear Magnetic Resonance Apparatus This invention relates to nuclear magnetic resonance (NMR) apparatus.
Inserted (or implanted) NMR coils can be sited in many cases close to a lesion which it is proposed to treat by the application of an external therapy remotely targeted at the lesion. Many therapies of interventional MRI are thermal in nature, and involve energies which are intentionally destructive of tissue locally. Such therapies include rf hyperthermia, laser ablation and focussed ultrasound. These therapies depend on assumptions about tissue properties in assessing their exact energy profiles, and the location of the focus, or principal region of heat deposition. Because of uncertainties in in vivo temperature measurement, pilot energy depositions are not a satisfactory method of determining energy patterns in human subjects.
According to the present invention suitable transducers are located in the body of the inserted or implanted NMR receiver coil which is being used to monitor the therapy, thus alleviating the aforementioned problem.
The method suggested here is particularly relevant to rf hyperthermia and focussed ultrasound. In both of these the exact distribution of energy inside the relevant tissue is important but hard to deternune.
If internal coils (of those for the anus, rectum etc.) are used to obtain better quality images of intemal structures during therapy, the coil formers can be used to locate transducers which can detect the particular radiation at low intensity (well below the level needed to damage tissue). The beams of the energy source can then be steered to target the transducers, which can easily be sensitive enough to avoid any extensible heating of local tissues, and so to establish the beam characteristics of the radiation source near to the target region. The location of the coil in the tissue can be determined from images; if the location of the transducers in the coil former is known, then the shape and size of the beam can be determined as the transducers of the therapy source are adjusted.
Conveniently, more than one transducer can be distributed around the NMR coil to provide a swifter means of detecting beam shape and size if it is not very well localised (as in the case of rf hyperthermia) and to help, by providing additional information for triangulation to provide a better measure of the effective location of the beam relative to the transducers. This will assist in working out any movements necessary to adjust the therapy sources to locate on its target accurately. Multiple sensors are advantageous if the coil is large enough (e.g. with a prostate coil monitoring ablation of a prostate, where three is a useful number), allowing greater interrogation of beam profiles, and better discrimination of its behaviour when being steered.
For focussed ultrasound (ultrasonic ablation) PLZT transducers can be used as they are directly compatible with MR. Multiple dipoles (appropriately tuned coils) can be used for rf hyperthermia (looking at the E-field rather than the H-field, though the latter can be monitored also).

Claims (3)

1. An implant coil, for use with magnetic resonance imaging apparatus, which is designed to be inserted into and removed from a patient and which comprises a former upon which the coil is mounted is characterised in that the former also carries at least one transducer or sensor by which the targeting of energy relating to an interventional procedure to an area in the vicinity of the transducer may be controlled both as to position and strength.
2. An implant coil as claimed in Claim 1 in which the former carries at least two transducers which are so located with respect to one another as to facilitate the detection of the shape and size and position of an interventional energy beam targeted on the area of the patient adjacent the coil when the latter is in an inserted position within the patient.
3. An implant coil as claimed in Claim 1 or 2, for use with interventional ultrasound ablation, in which each transducer or sensor is made of PLZT.
GB9704883A 1996-11-12 1997-03-10 Insertable MRI RF coil with ultrasound, RF, or laser targeting transducers Withdrawn GB2319340A (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP97308882A EP0841576B1 (en) 1996-11-12 1997-11-05 Nuclear magnetic resonance apparatus
DE69728490T DE69728490T2 (en) 1996-11-12 1997-11-05 Magnetic magnetic resonance device
US08/966,823 US6320379B1 (en) 1996-11-12 1997-11-10 Nuclear magnetic resonance apparatus
JP9310503A JPH10151122A (en) 1996-11-12 1997-11-12 Nuclear magnetic resonance device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9623664.1A GB9623664D0 (en) 1996-11-12 1996-11-12 Nuclear magnetic resonance apparatus

Publications (2)

Publication Number Publication Date
GB9704883D0 GB9704883D0 (en) 1997-04-30
GB2319340A true GB2319340A (en) 1998-05-20

Family

ID=10802905

Family Applications (2)

Application Number Title Priority Date Filing Date
GBGB9623664.1A Pending GB9623664D0 (en) 1996-11-12 1996-11-12 Nuclear magnetic resonance apparatus
GB9704883A Withdrawn GB2319340A (en) 1996-11-12 1997-03-10 Insertable MRI RF coil with ultrasound, RF, or laser targeting transducers

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GBGB9623664.1A Pending GB9623664D0 (en) 1996-11-12 1996-11-12 Nuclear magnetic resonance apparatus

Country Status (1)

Country Link
GB (2) GB9623664D0 (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4960109A (en) * 1988-06-21 1990-10-02 Massachusetts Institute Of Technology Multi-purpose temperature sensing probe for hyperthermia therapy
WO1993008733A1 (en) * 1991-11-05 1993-05-13 Brigham & Women's Hospital Apparatus for mr imaging and heating tissue
EP0558029A2 (en) * 1992-02-28 1993-09-01 Kabushiki Kaisha Toshiba Method and apparatus for ultrasonic wave medical treatment using computed tomography
US5307816A (en) * 1991-08-21 1994-05-03 Kabushiki Kaisha Toshiba Thrombus resolving treatment apparatus

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4960109A (en) * 1988-06-21 1990-10-02 Massachusetts Institute Of Technology Multi-purpose temperature sensing probe for hyperthermia therapy
US5307816A (en) * 1991-08-21 1994-05-03 Kabushiki Kaisha Toshiba Thrombus resolving treatment apparatus
WO1993008733A1 (en) * 1991-11-05 1993-05-13 Brigham & Women's Hospital Apparatus for mr imaging and heating tissue
EP0558029A2 (en) * 1992-02-28 1993-09-01 Kabushiki Kaisha Toshiba Method and apparatus for ultrasonic wave medical treatment using computed tomography

Also Published As

Publication number Publication date
GB9623664D0 (en) 1997-01-08
GB9704883D0 (en) 1997-04-30

Similar Documents

Publication Publication Date Title
EP0614651B1 (en) Ultrasonic wave medical treatment apparatus suitable for use under guidance of magnetic resonance imaging
EP1110508B1 (en) Apparatus for ultrasonic wave medical treatment using computed tomography
EP0627206B1 (en) Apparatus for ultrasound medical treatment
McDannold Quantitative MRI-based temperature mapping based on the proton resonant frequency shift: review of validation studies
US5368032A (en) Manually positioned focussed energy system guided by medical imaging
Hynynen et al. Pre-clinical testing of a phased array ultrasound system for MRI-guided noninvasive surgery of the brain—a primate study
CN102802728B (en) The treatment that MR imaging guides
JP5341884B2 (en) Image guided treatment
US9669240B2 (en) Therapy system for depositing energy
US20110306870A1 (en) Therapeutic apparatus for treating a subject using magnetic nanoparticles
US8024025B2 (en) T1-corrected proton resonance frequency shift thermometry
Gorny et al. MR guided focused ultrasound: technical acceptance measures for a clinical system
JPH06315541A (en) Medical treatment device using image diagnostic device
WO2010092495A1 (en) Method and system of tracking and mapping in a medical procedure
JP2004358264A (en) Ultrasonic therapeutic apparatus
US6320379B1 (en) Nuclear magnetic resonance apparatus
GB2319340A (en) Insertable MRI RF coil with ultrasound, RF, or laser targeting transducers
JP2004344672A (en) Ultrasonic treatment apparatus
JP3369504B2 (en) Ultrasound therapy equipment
Diederich et al. MR thermal monitoring of ultrasound interstitial thermal therapy
Gould et al. Monitoring of interstitial laser thermotherapy with heat-sensitive colour subtraction magnetic resonance imaging: calibration with absolute tissue temperature and correlation with predicted lesion size
JP2004321823A (en) Ultrasonic therapy apparatus
Chauhan et al. Imaging Ultrasound Guidance and on‐line Estimation of Thermal Behavior in HIFU Exposed Targets
JPH06261885A (en) Magnetic resonance video device provided with medical treatment mechanism

Legal Events

Date Code Title Description
WAP Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)