JP3825051B2 - 吸入装置 - Google Patents

吸入装置 Download PDF

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Publication number
JP3825051B2
JP3825051B2 JP51334497A JP51334497A JP3825051B2 JP 3825051 B2 JP3825051 B2 JP 3825051B2 JP 51334497 A JP51334497 A JP 51334497A JP 51334497 A JP51334497 A JP 51334497A JP 3825051 B2 JP3825051 B2 JP 3825051B2
Authority
JP
Japan
Prior art keywords
chamber
inhaler
dispersion
dispersion chamber
piston
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP51334497A
Other languages
English (en)
Japanese (ja)
Other versions
JPH11511372A5 (enExample
JPH11511372A (ja
Inventor
バリィ,エルナ
イェップソン,マグヌス
マキャンドリュー,ジョン・エイ
レベル,ウィリアム・ジェイ
ロバートソン,ポール・エイ
Original Assignee
アストラ・アクチエボラーグ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by アストラ・アクチエボラーグ filed Critical アストラ・アクチエボラーグ
Publication of JPH11511372A publication Critical patent/JPH11511372A/ja
Publication of JPH11511372A5 publication Critical patent/JPH11511372A5/ja
Application granted granted Critical
Publication of JP3825051B2 publication Critical patent/JP3825051B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0086Inhalation chambers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/0013Details of inhalators; Constructional features thereof with inhalation check valves
    • A61M15/0016Details of inhalators; Constructional features thereof with inhalation check valves located downstream of the dispenser, i.e. traversed by the product
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/0021Mouthpieces therefor
    • A61M15/0023Mouthpieces therefor retractable
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0086Inhalation chambers
    • A61M15/0088Inhalation chambers with variable volume
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0065Inhalators with dosage or measuring devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/06Solids
    • A61M2202/064Powder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/07General characteristics of the apparatus having air pumping means
    • A61M2205/071General characteristics of the apparatus having air pumping means hand operated
    • A61M2205/073Syringe, piston type

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Nozzles (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • External Artificial Organs (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
JP51334497A 1995-09-27 1996-09-23 吸入装置 Expired - Lifetime JP3825051B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9503344-5 1995-09-27
SE9503344A SE9503344D0 (sv) 1995-09-27 1995-09-27 Inhalation device
PCT/SE1996/001184 WO1997011732A1 (en) 1995-09-27 1996-09-23 Inhalation device

Publications (3)

Publication Number Publication Date
JPH11511372A JPH11511372A (ja) 1999-10-05
JPH11511372A5 JPH11511372A5 (enExample) 2004-09-30
JP3825051B2 true JP3825051B2 (ja) 2006-09-20

Family

ID=20399612

Family Applications (1)

Application Number Title Priority Date Filing Date
JP51334497A Expired - Lifetime JP3825051B2 (ja) 1995-09-27 1996-09-23 吸入装置

Country Status (28)

Country Link
US (1) US6286506B1 (enExample)
EP (1) EP0852508B1 (enExample)
JP (1) JP3825051B2 (enExample)
CN (1) CN1202117A (enExample)
AR (1) AR003595A1 (enExample)
AT (1) ATE228867T1 (enExample)
AU (1) AU714995B2 (enExample)
BR (1) BR9610693A (enExample)
CA (1) CA2232453A1 (enExample)
CZ (1) CZ92898A3 (enExample)
DE (1) DE69625219T2 (enExample)
EE (1) EE9800094A (enExample)
EG (1) EG20990A (enExample)
HU (1) HUP9802347A3 (enExample)
IL (1) IL123612A0 (enExample)
IS (1) IS4698A (enExample)
MY (1) MY132402A (enExample)
NO (1) NO981325L (enExample)
NZ (1) NZ318915A (enExample)
PL (1) PL325826A1 (enExample)
RU (1) RU2181058C2 (enExample)
SE (1) SE9503344D0 (enExample)
SG (2) SG90045A1 (enExample)
SK (1) SK39398A3 (enExample)
TR (2) TR199900011T2 (enExample)
TW (1) TW343925B (enExample)
WO (1) WO1997011732A1 (enExample)
ZA (1) ZA967805B (enExample)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9503344D0 (sv) 1995-09-27 1995-09-27 Astra Ab Inhalation device
SE9700935D0 (sv) * 1997-03-14 1997-03-14 Astra Ab Inhalation device
US6192876B1 (en) 1997-12-12 2001-02-27 Astra Aktiebolag Inhalation apparatus and method
EP1066074A1 (en) * 1998-03-16 2001-01-10 Inhale Therapeutic Systems, Inc. Aerosolized active agent delivery
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
SE0000935D0 (sv) * 2000-03-21 2000-03-21 Astrazeneca Ab An inhalation device
US6705316B2 (en) 2002-03-11 2004-03-16 Battelle Pulmonary Therapeutics, Inc. Pulmonary dosing system and method
AU2003220125B2 (en) 2002-03-20 2006-06-15 Mannkind Corporation Inhalation apparatus
PL1786784T3 (pl) 2004-08-20 2011-04-29 Mannkind Corp Kataliza syntezy diketopiperazyn
EP2314298B1 (en) 2004-08-23 2015-05-27 MannKind Corporation Microparticles comprising diketopiperazine salts for drug delivery
AU2006290870B2 (en) 2005-09-14 2013-02-28 Mannkind Corporation Method of drug formulation based on increasing the affinity of active agents for crystalline microparticle surfaces
DE102006007495A1 (de) * 2006-02-17 2007-08-23 Siegfried Generics International Ag Dispergiereinheit
DK1986679T3 (da) 2006-02-22 2017-11-20 Mannkind Corp Fremgangsmåde til forbedring af mikropartiklers farmaceutiske egenskaber omfattende diketopiperazin og et aktivt indholdsstof
GB2479843B (en) 2007-05-18 2012-02-29 Malvern Instr Ltd Method and apparatus for dispersing a sample of particulate material
WO2009079078A1 (en) 2007-12-14 2009-06-25 Labogroup S.A.S. Delivering aerosolizable food products
CN103252007B (zh) 2008-06-13 2016-06-22 曼金德公司 干粉吸入器和用于药物输送的系统
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
JP5479465B2 (ja) 2008-06-20 2014-04-23 マンカインド コーポレイション 吸入努力をリアルタイムにプロファイルする対話式機器および方法
TWI614024B (zh) 2008-08-11 2018-02-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
EP2676695A3 (en) 2009-03-11 2017-03-01 MannKind Corporation Apparatus, system and method for measuring resistance of an inhaler
KR101875969B1 (ko) 2009-06-12 2018-07-06 맨카인드 코포레이션 한정된 비표면적을 갖는 디케토피페라진 마이크로입자
WO2011056889A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
RU2531455C2 (ru) 2010-06-21 2014-10-20 Маннкайнд Корпорейшн Системы и способы доставки сухих порошковых лекарств
CN105667994B (zh) 2011-04-01 2018-04-06 曼金德公司 用于药物药盒的泡罩包装
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
WO2013063160A1 (en) 2011-10-24 2013-05-02 Mannkind Corporation Methods and compositions for treating pain
SG11201500218VA (en) 2012-07-12 2015-03-30 Mannkind Corp Dry powder drug delivery systems and methods
EP2911690A1 (en) 2012-10-26 2015-09-02 MannKind Corporation Inhalable influenza vaccine compositions and methods
EP3345643B1 (en) 2013-03-15 2021-01-06 Chris V. Ciancone Inhaler spacer and storage apparatus
EP2970149B1 (en) 2013-03-15 2019-08-21 MannKind Corporation Microcrystalline diketopiperazine compositions and methods
CN105451716A (zh) 2013-07-18 2016-03-30 曼金德公司 热稳定性干粉药物组合物和方法
WO2015021064A1 (en) 2013-08-05 2015-02-12 Mannkind Corporation Insufflation apparatus and methods
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
EP3693044A1 (en) 2019-02-07 2020-08-12 Koninklijke Philips N.V. Breath actuated inhalers

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA699313A (en) * 1964-12-08 G. Cheney Ralph Atomizer
US523992A (en) * 1894-08-07 End post for wire fences
US3636949A (en) * 1969-08-08 1972-01-25 Armstrong Kropp Dev Corp Inhalation-initiated aerosol dispenser
SE411705B (sv) 1976-11-09 1980-02-04 Draco Ab Anordning for generering av en avskermad, vesentligen drivmedelsfri aerosol
DE3274065D1 (de) 1981-07-08 1986-12-11 Draco Ab Powder inhalator
DE3429389C1 (de) * 1984-08-09 1986-03-13 Brugger, Inge, geb. Ritzau, 8130 Starnberg Inhalator
SE453566B (sv) 1986-03-07 1988-02-15 Draco Ab Anordning vid pulverinhalatorer
IT1217890B (it) * 1988-06-22 1990-03-30 Chiesi Farma Spa Dispositivo per l'inalazione di aerosol dosati
GB9004781D0 (en) * 1990-03-02 1990-04-25 Glaxo Group Ltd Device
DE4027749A1 (de) * 1990-09-01 1992-03-05 Pfeiffer Erich Gmbh & Co Kg Austragvorrichtung fuer medien
SE9002895D0 (sv) 1990-09-12 1990-09-12 Astra Ab Inhalation devices for dispensing powders i
CA2092614C (en) 1990-09-12 1996-04-09 Hans Bisgaard An inhaling device
FR2676929B1 (fr) * 1991-05-30 1994-02-11 Aerosols Bouchage Ste Fse Inhalateur de poudres.
US5341801A (en) * 1991-12-03 1994-08-30 Sandoz Ltd. Inhaler
DE4237568C1 (de) * 1992-11-06 1994-05-11 Dieter Dipl Ing Dr Med Koehler Verfahren und Vorrichtung zum Erzeugen eines Aerosols
DE4239402A1 (de) 1992-11-24 1994-05-26 Bayer Ag Pulverinhalator
SE9404439D0 (sv) 1994-12-21 1994-12-21 Astra Ab Inhalation device
US5823183A (en) * 1995-08-02 1998-10-20 Innovative Devices Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament
SE9503344D0 (sv) 1995-09-27 1995-09-27 Astra Ab Inhalation device

Also Published As

Publication number Publication date
EP0852508A1 (en) 1998-07-15
IL123612A0 (en) 1998-10-30
SG90046A1 (en) 2002-07-23
TR199900011T2 (xx) 1999-08-23
DE69625219T2 (de) 2003-08-28
WO1997011732A1 (en) 1997-04-03
NO981325L (no) 1998-05-26
SE9503344D0 (sv) 1995-09-27
AR003595A1 (es) 1998-08-05
ATE228867T1 (de) 2002-12-15
SG90045A1 (en) 2002-07-23
TR199800570T2 (xx) 1998-07-21
BR9610693A (pt) 1999-07-06
IS4698A (is) 1998-03-24
AU7102596A (en) 1997-04-17
TW343925B (en) 1998-11-01
EG20990A (en) 2000-08-30
HUP9802347A2 (hu) 1999-01-28
JPH11511372A (ja) 1999-10-05
NZ318915A (en) 1999-11-29
EE9800094A (et) 1998-10-15
DE69625219D1 (de) 2003-01-16
MX9802214A (es) 1998-08-30
CZ92898A3 (cs) 1998-10-14
PL325826A1 (en) 1998-08-03
CA2232453A1 (en) 1997-04-03
NO981325D0 (no) 1998-03-24
EP0852508B1 (en) 2002-12-04
US6286506B1 (en) 2001-09-11
ZA967805B (en) 1997-03-27
CN1202117A (zh) 1998-12-16
AU714995B2 (en) 2000-01-13
HUP9802347A3 (en) 1999-04-28
SK39398A3 (en) 1998-09-09
RU2181058C2 (ru) 2002-04-10
MY132402A (en) 2007-10-31

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