JP3635432B2 - オメプラゾールマグネシウムの製法 - Google Patents

オメプラゾールマグネシウムの製法 Download PDF

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Publication number
JP3635432B2
JP3635432B2 JP50400595A JP50400595A JP3635432B2 JP 3635432 B2 JP3635432 B2 JP 3635432B2 JP 50400595 A JP50400595 A JP 50400595A JP 50400595 A JP50400595 A JP 50400595A JP 3635432 B2 JP3635432 B2 JP 3635432B2
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JP
Japan
Prior art keywords
omeprazole magnesium
omeprazole
producing
magnesium
measured
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP50400595A
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English (en)
Japanese (ja)
Other versions
JPH08512315A (ja
Inventor
ケツルストリヨーム，ラース・オーケ
ニユグレン，モニカ・アンネリエ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20390588&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JP3635432(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Publication of JPH08512315A publication Critical patent/JPH08512315A/ja
Application granted granted Critical
Publication of JP3635432B2 publication Critical patent/JP3635432B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Contacts (AREA)
  • Electroplating Methods And Accessories (AREA)
  • Conductive Materials (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fats And Perfumes (AREA)
  • Medicinal Preparation (AREA)
  • Glass Compositions (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Powder Metallurgy (AREA)
JP50400595A 1993-07-09 1994-07-08 オメプラゾールマグネシウムの製法 Expired - Lifetime JP3635432B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9302396-8 1993-07-09
SE19939302396A SE9302396D0 (sv) 1993-07-09 1993-07-09 A novel compound form
PCT/SE1994/000680 WO1995001977A1 (en) 1993-07-09 1994-07-08 Magnesium omeprazole

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2001293480A Division JP3878826B2 (ja) 1993-07-09 2001-09-26 オメプラゾールマグネシウム

Publications (2)

Publication Number Publication Date
JPH08512315A JPH08512315A (ja) 1996-12-24
JP3635432B2 true JP3635432B2 (ja) 2005-04-06

Family

ID=20390588

Family Applications (2)

Application Number Title Priority Date Filing Date
JP50400595A Expired - Lifetime JP3635432B2 (ja) 1993-07-09 1994-07-08 オメプラゾールマグネシウムの製法
JP2001293480A Expired - Lifetime JP3878826B2 (ja) 1993-07-09 2001-09-26 オメプラゾールマグネシウム

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2001293480A Expired - Lifetime JP3878826B2 (ja) 1993-07-09 2001-09-26 オメプラゾールマグネシウム

Country Status (41)

Country Link
US (1) US5900424A (cs)
EP (2) EP0707580B1 (cs)
JP (2) JP3635432B2 (cs)
KR (1) KR100353783B1 (cs)
CN (1) CN1064680C (cs)
AT (1) ATE212628T1 (cs)
AU (1) AU679766B2 (cs)
BR (1) BR9406940A (cs)
CA (1) CA2166794C (cs)
CZ (1) CZ288933B6 (cs)
DE (2) DE69429774T2 (cs)
DK (1) DK0707580T3 (cs)
DZ (1) DZ1792A1 (cs)
EE (1) EE03127B1 (cs)
EG (1) EG21437A (cs)
ES (1) ES2100136T3 (cs)
FI (1) FI114154B (cs)
GR (1) GR970300015T1 (cs)
HR (1) HRP940385B1 (cs)
HU (1) HU226861B1 (cs)
IL (1) IL110190A (cs)
IS (1) IS2075B (cs)
MA (1) MA23257A1 (cs)
MX (1) MX9405217A (cs)
MY (1) MY113274A (cs)
NO (1) NO308702B1 (cs)
NZ (1) NZ268693A (cs)
PL (1) PL175999B1 (cs)
PT (1) PT707580E (cs)
RU (1) RU2139868C1 (cs)
SA (1) SA94150058B1 (cs)
SE (1) SE9302396D0 (cs)
SG (1) SG52464A1 (cs)
SI (1) SI0707580T1 (cs)
SK (1) SK281230B6 (cs)
TN (1) TNSN94079A1 (cs)
TW (1) TW504509B (cs)
UA (1) UA43343C2 (cs)
WO (1) WO1995001977A1 (cs)
YU (1) YU49193B (cs)
ZA (1) ZA944933B (cs)

Families Citing this family (95)

* Cited by examiner, † Cited by third party
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US6875872B1 (en) * 1993-05-28 2005-04-05 Astrazeneca Compounds
SE9301830D0 (sv) * 1993-05-28 1993-05-28 Ab Astra New compounds
SE9302395D0 (sv) * 1993-07-09 1993-07-09 Ab Astra New pharmaceutical formulation
SE9302396D0 (sv) * 1993-07-09 1993-07-09 Ab Astra A novel compound form
CA2193681A1 (en) * 1994-07-08 1996-01-25 Astra Aktiebolag New oral pharmaceutical formulation containing magnesium salt of omeprazole
JP3350054B2 (ja) * 1994-07-08 2002-11-25 アストラゼネカ・アクチエボラーグ 複数単位の錠剤化された剤形▲ｉ▼
SE9500478D0 (sv) * 1995-02-09 1995-02-09 Astra Ab New pharmaceutical formulation and process
US6645988B2 (en) * 1996-01-04 2003-11-11 Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US6489346B1 (en) * 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
US6699885B2 (en) * 1996-01-04 2004-03-02 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and methods of using same
SE9600070D0 (sv) 1996-01-08 1996-01-08 Astra Ab New oral pharmaceutical dosage forms
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DE19843413C1 (de) 1998-08-18 2000-03-30 Byk Gulden Lomberg Chem Fab Neue Salzform von Pantoprazol
US6733778B1 (en) 1999-08-27 2004-05-11 Andrx Pharmaceuticals, Inc. Omeprazole formulation
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WO2000028975A2 (en) * 1998-11-18 2000-05-25 Astrazeneca Ab Improved chemical process and pharmaceutical formulation
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US7271182B2 (en) 2000-08-04 2007-09-18 Takeda Pharmaceutical Company Limited Salts of benzimidazole compound and use thereof
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US6544556B1 (en) 2000-09-11 2003-04-08 Andrx Corporation Pharmaceutical formulations containing a non-steroidal antiinflammatory drug and a proton pump inhibitor
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SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
SE8301182D0 (sv) * 1983-03-04 1983-03-04 Haessle Ab Novel compounds
GB2189698A (en) * 1986-04-30 1987-11-04 Haessle Ab Coated omeprazole tablets
DE4035455A1 (de) * 1990-11-08 1992-05-14 Byk Gulden Lomberg Chem Fab Enantiomerentrennung
SE9302396D0 (sv) * 1993-07-09 1993-07-09 Ab Astra A novel compound form

Also Published As

Publication number Publication date
AU7198194A (en) 1995-02-06
IL110190A0 (en) 1994-10-21
ZA944933B (en) 1995-02-20
YU43694A (sh) 1997-07-31
HRP940385A2 (en) 1997-02-28
CN1126993A (zh) 1996-07-17
TNSN94079A1 (fr) 1995-04-25
NO308702B1 (no) 2000-10-16
CN1064680C (zh) 2001-04-18
IS4186A (is) 1995-01-10
RU2139868C1 (ru) 1999-10-20
NO960068D0 (no) 1996-01-05
NZ268693A (en) 1997-05-26
HK1008329A1 (en) 1999-05-07
AU679766B2 (en) 1997-07-10
DE69429774T2 (de) 2002-11-14
EE03127B1 (et) 1998-10-15
MY113274A (en) 2002-01-31
FI960101A0 (fi) 1996-01-09
IS2075B (is) 2005-12-15
DE707580T1 (de) 1997-09-04
EP1164132A2 (en) 2001-12-19
YU49193B (sh) 2004-09-03
PL312440A1 (en) 1996-04-29
DZ1792A1 (fr) 2002-02-17
NO960068L (no) 1996-01-05
GR970300015T1 (en) 1997-05-31
CA2166794C (en) 1997-03-04
SE9302396D0 (sv) 1993-07-09
FI960101L (fi) 1996-01-09
EP1164132A3 (en) 2002-01-02
BR9406940A (pt) 1996-09-10
ES2100136T1 (es) 1997-06-16
HUT75314A (en) 1997-05-28
JPH08512315A (ja) 1996-12-24
ES2100136T3 (es) 2002-09-01
EP0707580A1 (en) 1996-04-24
SG52464A1 (en) 1998-09-28
ATE212628T1 (de) 2002-02-15
EG21437A (en) 2001-10-31
KR100353783B1 (ko) 2004-04-03
US5900424A (en) 1999-05-04
HRP940385B1 (en) 2003-06-30
HU9503873D0 (en) 1996-02-28
PT707580E (pt) 2002-06-28
DK0707580T3 (da) 2002-04-15
CZ288933B6 (cs) 2001-09-12
JP3878826B2 (ja) 2007-02-07
DE69429774D1 (de) 2002-03-14
TW504509B (en) 2002-10-01
SI0707580T1 (en) 2002-06-30
EP0707580B1 (en) 2002-01-30
SA94150058B1 (ar) 2006-06-20
PL175999B1 (pl) 1999-03-31
MA23257A1 (fr) 1995-04-01
HU226861B1 (en) 2009-12-28
MX9405217A (es) 1995-01-31
JP2002105072A (ja) 2002-04-10
WO1995001977A1 (en) 1995-01-19
SK2296A3 (en) 1996-10-02
SK281230B6 (sk) 2001-01-18
CZ6996A3 (en) 1996-05-15
IL110190A (en) 2000-07-26
FI114154B (fi) 2004-08-31
UA43343C2 (uk) 2001-12-17

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