JP3336010B2 - 骨形成性蛋白の送達のための血餅−ポリマー・マトリックスの処方 - Google Patents
骨形成性蛋白の送達のための血餅−ポリマー・マトリックスの処方Info
- Publication number
- JP3336010B2 JP3336010B2 JP50721193A JP50721193A JP3336010B2 JP 3336010 B2 JP3336010 B2 JP 3336010B2 JP 50721193 A JP50721193 A JP 50721193A JP 50721193 A JP50721193 A JP 50721193A JP 3336010 B2 JP3336010 B2 JP 3336010B2
- Authority
- JP
- Japan
- Prior art keywords
- polymer matrix
- bone
- osteogenic
- poly
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/26—Mixtures of macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1875—Bone morphogenic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Dermatology (AREA)
- Transplantation (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Materials For Medical Uses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/776,514 US5171579A (en) | 1991-10-11 | 1991-10-11 | Formulations of blood clot-polymer matrix for delivery of osteogenic proteins |
| US776,514 | 1991-10-11 | ||
| PCT/US1992/008628 WO1993006872A1 (en) | 1991-10-11 | 1992-10-09 | Formulations of blood clot-polymer matrix for delivery of osteogenic proteins |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH07500038A JPH07500038A (ja) | 1995-01-05 |
| JP3336010B2 true JP3336010B2 (ja) | 2002-10-21 |
Family
ID=25107596
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP50721193A Expired - Fee Related JP3336010B2 (ja) | 1991-10-11 | 1992-10-09 | 骨形成性蛋白の送達のための血餅−ポリマー・マトリックスの処方 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5171579A (da) |
| EP (1) | EP0608313B1 (da) |
| JP (1) | JP3336010B2 (da) |
| KR (1) | KR0181984B1 (da) |
| AT (1) | ATE189611T1 (da) |
| AU (1) | AU669133B2 (da) |
| DE (1) | DE69230670T2 (da) |
| DK (1) | DK0608313T3 (da) |
| ES (1) | ES2145013T3 (da) |
| GR (1) | GR3033204T3 (da) |
| WO (1) | WO1993006872A1 (da) |
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-
1991
- 1991-10-11 US US07/776,514 patent/US5171579A/en not_active Expired - Lifetime
-
1992
- 1992-10-09 AT AT92921634T patent/ATE189611T1/de not_active IP Right Cessation
- 1992-10-09 ES ES92921634T patent/ES2145013T3/es not_active Expired - Lifetime
- 1992-10-09 JP JP50721193A patent/JP3336010B2/ja not_active Expired - Fee Related
- 1992-10-09 DE DE69230670T patent/DE69230670T2/de not_active Expired - Fee Related
- 1992-10-09 KR KR1019940701180A patent/KR0181984B1/ko not_active IP Right Cessation
- 1992-10-09 DK DK92921634T patent/DK0608313T3/da active
- 1992-10-09 AU AU27885/92A patent/AU669133B2/en not_active Ceased
- 1992-10-09 EP EP92921634A patent/EP0608313B1/en not_active Expired - Lifetime
- 1992-10-09 WO PCT/US1992/008628 patent/WO1993006872A1/en active IP Right Grant
-
2000
- 2000-04-12 GR GR20000400898T patent/GR3033204T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| US5171579A (en) | 1992-12-15 |
| JPH07500038A (ja) | 1995-01-05 |
| EP0608313A1 (en) | 1994-08-03 |
| WO1993006872A1 (en) | 1993-04-15 |
| DK0608313T3 (da) | 2000-05-15 |
| KR0181984B1 (ko) | 1999-04-01 |
| AU669133B2 (en) | 1996-05-30 |
| GR3033204T3 (en) | 2000-08-31 |
| DE69230670T2 (de) | 2000-09-21 |
| ES2145013T3 (es) | 2000-07-01 |
| ATE189611T1 (de) | 2000-02-15 |
| AU2788592A (en) | 1993-05-03 |
| DE69230670D1 (de) | 2000-03-16 |
| EP0608313B1 (en) | 2000-02-09 |
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