JP3174767B2 - 選択的トロンビン抑制剤として有用な芳香族アミジン誘導体 - Google Patents

選択的トロンビン抑制剤として有用な芳香族アミジン誘導体

Info

Publication number
JP3174767B2
JP3174767B2 JP37584798A JP37584798A JP3174767B2 JP 3174767 B2 JP3174767 B2 JP 3174767B2 JP 37584798 A JP37584798 A JP 37584798A JP 37584798 A JP37584798 A JP 37584798A JP 3174767 B2 JP3174767 B2 JP 3174767B2
Authority
JP
Japan
Prior art keywords
compound
pyrrolidinyl
ethyl
formula
carbonyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP37584798A
Other languages
English (en)
Japanese (ja)
Other versions
JPH11246554A (ja
Inventor
グー，ボン・アム
キム，ジョン・ミン
Original Assignee
シー アンド シー リサーチ ラボラトリーズ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by シー アンド シー リサーチ ラボラトリーズ filed Critical シー アンド シー リサーチ ラボラトリーズ
Publication of JPH11246554A publication Critical patent/JPH11246554A/ja
Application granted granted Critical
Publication of JP3174767B2 publication Critical patent/JP3174767B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP37584798A 1997-11-29 1998-11-30 選択的トロンビン抑制剤として有用な芳香族アミジン誘導体 Expired - Fee Related JP3174767B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1019970064628A KR19990043605A (ko) 1997-11-29 1997-11-29 선택적 트롬빈 억제제로 유용한 방향족 아미딘유도체
KR97-64628 1997-11-29

Publications (2)

Publication Number Publication Date
JPH11246554A JPH11246554A (ja) 1999-09-14
JP3174767B2 true JP3174767B2 (ja) 2001-06-11

Family

ID=19526058

Family Applications (1)

Application Number Title Priority Date Filing Date
JP37584798A Expired - Fee Related JP3174767B2 (ja) 1997-11-29 1998-11-30 選択的トロンビン抑制剤として有用な芳香族アミジン誘導体

Country Status (2)

Country Link
JP (1) JP3174767B2 (ko)
KR (1) KR19990043605A (ko)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6294436B1 (en) 1999-08-16 2001-09-25 Infineon Technologies Ag Method for fabrication of enlarged stacked capacitors using isotropic etching

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7361663B2 (en) * 1999-11-10 2008-04-22 Aventis Pharmaceuticals Inc. N-acylpyrrolidin-2-ylalkylbenzamidine derivatives as inhibitors of factor Xa

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA928276B (en) * 1991-10-31 1993-05-06 Daiichi Seiyaku Co Aromatic amidine derivates and salts thereof.
ES2171945T3 (es) * 1996-05-31 2002-09-16 C & C Res Lab Derivados aromaticos de amidina que sirven de inhibidores selectivos de la trombina.
KR19990015206A (ko) * 1997-08-02 1999-03-05 이경하 선택적 트롬빈 억제활성을 갖는 치환된 방향족 유도체

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6294436B1 (en) 1999-08-16 2001-09-25 Infineon Technologies Ag Method for fabrication of enlarged stacked capacitors using isotropic etching

Also Published As

Publication number Publication date
KR19990043605A (ko) 1999-06-15
JPH11246554A (ja) 1999-09-14

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Legal Events

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LAPS Cancellation because of no payment of annual fees