JP3157190B2 - 薬剤のための味マスキング及び持効性皮膜 - Google Patents

薬剤のための味マスキング及び持効性皮膜

Info

Publication number
JP3157190B2
JP3157190B2 JP14418391A JP14418391A JP3157190B2 JP 3157190 B2 JP3157190 B2 JP 3157190B2 JP 14418391 A JP14418391 A JP 14418391A JP 14418391 A JP14418391 A JP 14418391A JP 3157190 B2 JP3157190 B2 JP 3157190B2
Authority
JP
Japan
Prior art keywords
drug
coating
coated
granules
polymer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP14418391A
Other languages
English (en)
Japanese (ja)
Other versions
JPH06316536A (ja
Inventor
エドワード・ジエイ・ロシユ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MCNELL−PPC, INCORPORATED
Original Assignee
MCNELL−PPC, INCORPORATED
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MCNELL−PPC, INCORPORATED filed Critical MCNELL−PPC, INCORPORATED
Publication of JPH06316536A publication Critical patent/JPH06316536A/ja
Application granted granted Critical
Publication of JP3157190B2 publication Critical patent/JP3157190B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5036Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5036Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP14418391A 1990-05-23 1991-05-21 薬剤のための味マスキング及び持効性皮膜 Expired - Lifetime JP3157190B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US07/528,003 US5075114A (en) 1990-05-23 1990-05-23 Taste masking and sustained release coatings for pharmaceuticals
US528003 1990-05-23
IN325CA1991 IN172428B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1990-05-23 1991-04-29

Publications (2)

Publication Number Publication Date
JPH06316536A JPH06316536A (ja) 1994-11-15
JP3157190B2 true JP3157190B2 (ja) 2001-04-16

Family

ID=26324259

Family Applications (1)

Application Number Title Priority Date Filing Date
JP14418391A Expired - Lifetime JP3157190B2 (ja) 1990-05-23 1991-05-21 薬剤のための味マスキング及び持効性皮膜

Country Status (11)

Country Link
US (1) US5075114A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0459695B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JP3157190B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU639334B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA2042289C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2073677T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR1002092B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IE (1) IE67062B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IN (1) IN172428B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ238131A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT97739B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (151)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5460825A (en) * 1990-05-23 1995-10-24 Mcneil-Ppc, Inc. Taste mask coatings for preparing chewable pharmaceutical tablets
DK0537139T3 (da) * 1990-07-02 1994-08-22 Boehringer Mannheim Gmbh Fremgangsmåde til fremstilling af formede, pressede dosisenheder med forsinket frigørelse og dertil svarende dosisenhed
CA2104684A1 (en) * 1991-03-04 1992-09-05 Mahdi B. Fawzi Salts/ion pairs of non-steroidal anti-inflammatory drugs in various dosage forms
CA2107229C (en) * 1991-04-30 1997-07-22 Thomas A. Wheatley Taste-masked medicaments and their preparation
CA2079934C (en) * 1991-10-15 2002-09-03 Edward J. Roche Taste mask coatings for preparing chewable pharmaceutical tablets
GR1002332B (el) * 1992-05-21 1996-05-16 Mcneil-Ppc Inc. Νεες φαρμακευτικες συνθεσεις που περιεχουν σιμεθεικονη.
EP0572731A1 (en) * 1992-06-01 1993-12-08 The Procter & Gamble Company Chewable preparation containing a decongestant
ES2174849T3 (es) * 1992-06-04 2002-11-16 Smithkline Beecham Corp Composiciones farmaceuticas con sabor agradable.
US5837277A (en) * 1992-06-04 1998-11-17 Smithkline Beecham Corporation Palatable pharmaceutical compositions
GB9221414D0 (en) * 1992-10-13 1992-11-25 Glaxo Group Ltd Pharmaceutical compositions
CA2146999A1 (en) * 1992-10-16 1994-04-28 Stephen John Douglas Taste-masking compositions of ranitidine
WO1994012157A1 (en) * 1992-11-30 1994-06-09 Kv Pharmaceutical Company Tastemasked pharmaceutical materials
CA2110313C (en) * 1992-12-01 2004-10-26 Edward John Roche Pharmaceutical compositions containing a guanidinothiazole compound and antacids
US6313202B1 (en) * 1993-05-28 2001-11-06 Eastman Chemical Company Cellulose ester blends
WO1995001782A2 (en) * 1993-07-09 1995-01-19 R.P. Scherer Corporation Method for making freeze dried drug dosage forms
CA2128820A1 (en) * 1993-07-27 1995-01-28 Walter G. Gowan, Jr. Rapidly disintegrating pharmaceutical dosage form and process for preparation thereof
CA2128821A1 (en) * 1993-07-27 1995-01-28 Dilip J. Gole Freeze-dried pharmaceutical dosage form and process for separation thereof
US5622980A (en) * 1993-08-17 1997-04-22 Applied Analytical Industries, Inc. Oral compositions of H2-antagonists
HUT72408A (en) * 1993-09-10 1996-04-29 Egyt Gyogyszervegyeszeti Gyar Process for producing tablets containing acetyl-salicylic acid
US5536505A (en) * 1993-12-15 1996-07-16 Eastman Chemical Company Controlled release matrix system using cellulose acetate/poly-2-ethyl-2-oxazoline blends
US5470865A (en) * 1994-08-30 1995-11-28 Eli Lilly And Company Pharmaceutical composition
US5529783A (en) * 1994-12-19 1996-06-25 Mcneil-Ppc, Inc. Rotor granulation and coating of acetaminophen, pseudoephedrine, chlorpheniramine, and, optionally dextromethorphan
AUPN605795A0 (en) * 1995-10-19 1995-11-09 F.H. Faulding & Co. Limited Analgesic pharmaceutical composition
US8071128B2 (en) 1996-06-14 2011-12-06 Kyowa Hakko Kirin Co., Ltd. Intrabuccally rapidly disintegrating tablet and a production method of the tablets
CA2264182A1 (en) 1996-08-23 1998-02-26 Algos Pharmaceutical Corporation Anticonvulsant containing composition for treating neuropathic pain
CN1233954A (zh) * 1996-10-01 1999-11-03 西马实验室股份有限公司 掩盖味道的微胶囊组合物及其制备方法
JP3001440B2 (ja) * 1996-11-25 2000-01-24 日本電気通信システム株式会社 仮想lan方式
US5904937A (en) * 1997-10-03 1999-05-18 Fmc Corporation Taste masked pharmaceutical compositions
UA65607C2 (uk) * 1998-03-04 2004-04-15 Орто-Макнейл Фармацевтикал, Інк. Фармацевтична композиція (варіанти) та спосіб її приготування
US6270790B1 (en) 1998-08-18 2001-08-07 Mxneil-Ppc, Inc. Soft, convex shaped chewable tablets having reduced friability
SK8252001A3 (en) * 1998-12-18 2001-12-03 Abbott Lab Controlled release formulation of divalproex sodium
US6270807B1 (en) 1999-03-02 2001-08-07 L. Perrigo Company Taste-masked pharmaceutical composition
US6211246B1 (en) * 1999-06-10 2001-04-03 Mcneil-Ppc, Inc. Rapidly absorbed liquid compositions
US6428809B1 (en) * 1999-08-18 2002-08-06 Microdose Technologies, Inc. Metering and packaging of controlled release medication
US6451345B1 (en) 2000-01-20 2002-09-17 Eurand Pharmaceuticals Ltd. Functional coating of linezolid microcapsules for taste-masking and associated formulation for oral administration
US20020119196A1 (en) * 2000-12-21 2002-08-29 Narendra Parikh Texture masked particles containing an active ingredient
US20020122823A1 (en) * 2000-12-29 2002-09-05 Bunick Frank J. Soft tablet containing dextrose monohydrate
WO2002096392A1 (en) * 2001-05-31 2002-12-05 Cima Labs Inc. Taste-masking of highly water-soluble drugs
GB0113839D0 (en) * 2001-06-07 2001-08-01 Boots Co Plc Therapeutic agents
US7914811B2 (en) 2001-06-29 2011-03-29 Mcneil-Ppc, Inc. Brittle-coating, soft core dosage form
US20030060422A1 (en) 2001-08-31 2003-03-27 Balaji Venkataraman Tannate compositions and methods of treatment
US6742646B2 (en) * 2001-09-28 2004-06-01 Mcneil-Ppc, Inc. Systems, methods and apparatuses for manufacturing dosage forms
US7122143B2 (en) 2001-09-28 2006-10-17 Mcneil-Ppc, Inc. Methods for manufacturing dosage forms
US7323192B2 (en) 2001-09-28 2008-01-29 Mcneil-Ppc, Inc. Immediate release tablet
US6767200B2 (en) * 2001-09-28 2004-07-27 Mcneil-Ppc, Inc. Systems, methods and apparatuses for manufacturing dosage forms
US6837696B2 (en) * 2001-09-28 2005-01-04 Mcneil-Ppc, Inc. Apparatus for manufacturing dosage forms
US7217381B2 (en) * 2001-09-28 2007-05-15 Mcneil-Ppc, Inc. Systems, methods and apparatuses for manufacturing dosage forms
EP1429745A2 (en) * 2001-09-28 2004-06-23 McNEIL-PPC, INC. Composite dosage forms having an inlaid portion
US7101573B2 (en) * 2001-09-28 2006-09-05 Mcneil-Pcc, Inc. Simethicone solid oral dosage form
US6982094B2 (en) 2001-09-28 2006-01-03 Mcneil-Ppc, Inc. Systems, methods and apparatuses for manufacturing dosage forms
US7838026B2 (en) 2001-09-28 2010-11-23 Mcneil-Ppc, Inc. Burst-release polymer composition and dosage forms comprising the same
US9358214B2 (en) 2001-10-04 2016-06-07 Adare Pharmaceuticals, Inc. Timed, sustained release systems for propranolol
US6723348B2 (en) * 2001-11-16 2004-04-20 Ethypharm Orodispersible tablets containing fexofenadine
US6753009B2 (en) 2002-03-13 2004-06-22 Mcneil-Ppc, Inc. Soft tablet containing high molecular weight polyethylene oxide
US7169450B2 (en) * 2002-05-15 2007-01-30 Mcneil-Ppc, Inc. Enrobed core
US7807197B2 (en) 2002-09-28 2010-10-05 Mcneil-Ppc, Inc. Composite dosage forms having an inlaid portion
US20040081695A1 (en) * 2002-09-28 2004-04-29 Sowden Harry S Dosage forms having an inner core and an outer shell
US20040109889A1 (en) * 2002-12-04 2004-06-10 Bunick Frank J. Surface treatment composition for soft substrates
US8367111B2 (en) 2002-12-31 2013-02-05 Aptalis Pharmatech, Inc. Extended release dosage forms of propranolol hydrochloride
US20040258752A1 (en) * 2003-01-31 2004-12-23 Paruthi Manoj Kumar Taste masking pharmaceutical composition and process for its preparation
US20040265373A1 (en) * 2003-06-27 2004-12-30 David Wynn Soft tablet containing high molecular weight cellulosics
US20040265372A1 (en) * 2003-06-27 2004-12-30 David Wynn Soft tablet containing high molecular weight cellulosics
US7632521B2 (en) 2003-07-15 2009-12-15 Eurand, Inc. Controlled release potassium chloride tablets
EP1656117A1 (en) * 2003-08-11 2006-05-17 Merck Frosst Canada Ltd. Flavored taste-masked pharmaceutical formulation made using a one-step coating process
US20050069590A1 (en) * 2003-09-30 2005-03-31 Buehler Gail K. Stable suspensions for medicinal dosages
US20050074514A1 (en) * 2003-10-02 2005-04-07 Anderson Oliver B. Zero cycle molding systems, methods and apparatuses for manufacturing dosage forms
JPWO2005039542A1 (ja) * 2003-10-27 2007-02-15 アステラス製薬株式会社 口腔内崩壊錠用の薬物含有被覆微粒子
US20050175689A1 (en) * 2003-10-27 2005-08-11 Yamanouchi Pharmaceutical Co., Ltd. Coated fine particles containing drug for intrabuccally fast disintegrating tablet
US7201920B2 (en) 2003-11-26 2007-04-10 Acura Pharmaceuticals, Inc. Methods and compositions for deterring abuse of opioid containing dosage forms
US8039482B2 (en) * 2004-03-25 2011-10-18 Astellas Pharma Inc. Composition of solifenacin or salt thereof for use in solid formulation
US8545881B2 (en) 2004-04-19 2013-10-01 Eurand Pharmaceuticals, Ltd. Orally disintegrating tablets and methods of manufacture
US8747895B2 (en) 2004-09-13 2014-06-10 Aptalis Pharmatech, Inc. Orally disintegrating tablets of atomoxetine
US9884014B2 (en) 2004-10-12 2018-02-06 Adare Pharmaceuticals, Inc. Taste-masked pharmaceutical compositions
NZ589750A (en) 2004-10-21 2012-07-27 Aptalis Pharmatech Inc Taste-masked pharmaceutical compositions with gastrosoluble pore-formers
US8383159B2 (en) * 2004-10-27 2013-02-26 Mcneil-Ppc, Inc. Dosage forms having a microreliefed surface and methods and apparatus for their production
US20060088587A1 (en) * 2004-10-27 2006-04-27 Bunick Frank J Dosage forms having a microreliefed surface and methods and apparatus for their production
US20070190133A1 (en) * 2004-10-27 2007-08-16 Bunick Frank J Dosage forms having a microreliefed surface and methods and apparatus for their production
US20070281022A1 (en) * 2004-10-27 2007-12-06 Bunick Frank J Dosage forms having a microreliefed surface and methods and apparatus for their production
US20060088593A1 (en) * 2004-10-27 2006-04-27 Bunick Frank J Dosage forms having a microreliefed surface and methods and apparatus for their production
US20060088586A1 (en) * 2004-10-27 2006-04-27 Bunick Frank J Dosage forms having a microreliefed surface and methods and apparatus for their production
US20060087051A1 (en) * 2004-10-27 2006-04-27 Bunick Frank J Dosage forms having a microreliefed surface and methods and apparatus for their production
WO2006070735A1 (ja) * 2004-12-27 2006-07-06 Astellas Pharma Inc. ソリフェナシンまたはその塩の安定な粒子状医薬組成物
US8673352B2 (en) 2005-04-15 2014-03-18 Mcneil-Ppc, Inc. Modified release dosage form
US9161918B2 (en) 2005-05-02 2015-10-20 Adare Pharmaceuticals, Inc. Timed, pulsatile release systems
EP1911444A1 (en) * 2005-07-20 2008-04-16 Astellas Pharma Inc. Drug-containing coated fine particle for intrabuccally disintegrating preparation and method of producing the same
US7815939B2 (en) * 2005-07-20 2010-10-19 Astellas Pharma Inc. Coated fine particles containing drug for intrabuccally fast disintegrating dosage forms
US8778395B2 (en) 2005-08-11 2014-07-15 Andrx Labs, Llc Diltiazem controlled release formulation and method of manufacture
US20070077300A1 (en) * 2005-09-30 2007-04-05 Wynn David W Oral compositions containing a salivation inducing agent
MX2008012575A (es) * 2006-03-28 2008-12-17 Mcneil Ppc Inc Revestimientos no homogeneos de formas de dosificacion.
US20070286903A1 (en) * 2006-06-13 2007-12-13 Becicka Brian T Composition and method for taste masking
US20080031927A1 (en) * 2006-07-11 2008-02-07 Catani Steven J Solid oral dosage vitamin and mineral compositions
AU2007309281B2 (en) 2006-10-20 2013-10-31 Johnson & Johnson Consumer Inc. Acetaminophen / ibuprofen combinations
US20080194307A1 (en) * 2007-02-13 2008-08-14 Jeff Sanger Sports-based game of chance
GB2447898B (en) * 2007-03-24 2011-08-17 Reckitt Benckiser Healthcare A tablet having improved stability with at least two actives
CN101778642B (zh) * 2007-06-06 2012-07-11 诺华丝国际股份有限公司 促进骨和关节的生长、修复以及维持的食品添加剂
US20090004248A1 (en) * 2007-06-29 2009-01-01 Frank Bunick Dual portion dosage lozenge form
WO2009039049A1 (en) * 2007-09-17 2009-03-26 Mcneil-Ppc, Inc. Dip coated compositions containing copolymer of polyvinyl alcohol and polyethylene glycol and a gum
US8439033B2 (en) 2007-10-09 2013-05-14 Microdose Therapeutx, Inc. Inhalation device
KR101560176B1 (ko) 2007-10-31 2015-10-14 맥네일-피피씨, 인코포레이티드 구강내 붕해성 투여 형태
CN101917975B (zh) * 2007-12-21 2013-05-08 麦克内尔-Ppc股份有限公司 片剂的制造
KR20100129740A (ko) * 2008-02-19 2010-12-09 맥네일-피피씨, 인코포레이티드 아밀로스 함량이 높은 전분을 포함하는 침지 코팅 조성물
US8372432B2 (en) 2008-03-11 2013-02-12 Depomed, Inc. Gastric retentive extended-release dosage forms comprising combinations of a non-opioid analgesic and an opioid analgesic
MX2010009990A (es) 2008-03-11 2010-12-15 Depomed Inc Formas de dosificación gástricas retentivas de liberación prolongada que comprenden combinaciones de un analgésico no opioide y un analgésico opioide.
EP2309999A1 (en) * 2008-06-26 2011-04-20 McNeil-PPC, Inc. Coated particles containing pharmaceutically active agents
US8323262B2 (en) 2008-07-08 2012-12-04 Hyperbranch Medical Technology, Inc. Self-contained medical applicators for multiple component formulations, and methods of use thereof
CN102112114A (zh) * 2008-08-08 2011-06-29 麦克内尔-Ppc股份有限公司 使用三氯蔗糖作为制粒剂
WO2010051312A1 (en) * 2008-10-31 2010-05-06 Mcneil-Ppc, Inc. Osmotic tablet with a compressed outer coating
US20100247586A1 (en) * 2009-03-27 2010-09-30 Andreas Hugerth Multi-Portion Intra-Oral Dosage Form With Organoleptic Properties
JP2012530781A (ja) * 2009-06-22 2012-12-06 ワイス・エルエルシー イブプロフェンナトリウムタブレット、およびイブプロフェンナトリウムを含有する医薬組成物の製造方法
CA2766202A1 (en) 2009-06-29 2011-01-06 Mcneil-Ppc, Inc. Pharmaceutical tablet containing a liquid filled capsule
US20110070301A1 (en) 2009-09-24 2011-03-24 Luber Joseph R Orally transformable tablets
US20110318411A1 (en) 2010-06-24 2011-12-29 Luber Joseph R Multi-layered orally disintegrating tablet and the manufacture thereof
US8313768B2 (en) 2009-09-24 2012-11-20 Mcneil-Ppc, Inc. Manufacture of tablet having immediate release region and sustained release region
US20110077222A1 (en) * 2009-09-30 2011-03-31 Mallinckrodt Inc. Sustained-Release Opiate and Opiate Derivative Compositions
CA2775890C (en) 2009-09-30 2016-06-21 Acura Pharmaceuticals, Inc. Methods and compositions for deterring abuse
RU2563623C2 (ru) 2009-12-02 2015-09-20 Апталис Фарма Лимитед Микрокапсулы фексофенадина и содержащие их композиции
US9198861B2 (en) 2009-12-22 2015-12-01 Mallinckrodt Llc Methods of producing stabilized solid dosage pharmaceutical compositions containing morphinans
WO2011087765A2 (en) 2009-12-22 2011-07-21 Mallinckrodt Inc. Methods of producing stabilized solid pharmaceutical compositions containing morphinans
US20110150989A1 (en) * 2009-12-22 2011-06-23 Mallinkckrodt Inc. Methods of Producing Stabilized Solid Dosage Pharmaceutical Compositions Containing Morphinans
US8597681B2 (en) 2009-12-22 2013-12-03 Mallinckrodt Llc Methods of producing stabilized solid dosage pharmaceutical compositions containing morphinans
JP6017961B2 (ja) 2010-01-05 2016-11-02 マイクロドース セラピューテクス,インコーポレイテッド 吸入デバイスおよび方法
WO2012039789A1 (en) 2010-09-22 2012-03-29 Mcneil-Ppc, Inc. Manufacture of variable density dosage forms utilizing radiofrequency energy
CA2810837A1 (en) 2010-09-22 2012-03-29 Joseph R. Luber Manufacture of tablets from energy-applied powder blend
US8858963B1 (en) 2011-05-17 2014-10-14 Mallinckrodt Llc Tamper resistant composition comprising hydrocodone and acetaminophen for rapid onset and extended duration of analgesia
US9050335B1 (en) 2011-05-17 2015-06-09 Mallinckrodt Llc Pharmaceutical compositions for extended release of oxycodone and acetaminophen resulting in a quick onset and prolonged period of analgesia
US8741885B1 (en) 2011-05-17 2014-06-03 Mallinckrodt Llc Gastric retentive extended release pharmaceutical compositions
US20130295174A1 (en) 2012-05-01 2013-11-07 Mcneil-Ppc, Inc. Tablet comprising a first and second region
US9445971B2 (en) 2012-05-01 2016-09-20 Johnson & Johnson Consumer Inc. Method of manufacturing solid dosage form
US9233491B2 (en) 2012-05-01 2016-01-12 Johnson & Johnson Consumer Inc. Machine for production of solid dosage forms
US9511028B2 (en) 2012-05-01 2016-12-06 Johnson & Johnson Consumer Inc. Orally disintegrating tablet
CN104968333B (zh) 2012-11-30 2018-07-10 阿库拉制药公司 活性药物成分的自调节释放
CA2936216C (en) 2014-01-10 2021-10-26 Johnson & Johnson Consumer Inc. Process for making tablet using radiofrequency and lossy coated particles
CA2943728C (en) 2014-03-26 2020-03-24 Sun Pharma Advanced Research Company Ltd. Abuse deterrent immediate release biphasic matrix solid dosage form
US20150328162A1 (en) * 2014-05-15 2015-11-19 Mario Medri Pharmaceutical preparations
EP2952103B1 (de) 2014-06-05 2019-05-08 Symrise AG Stoffgemische
MA40859A (fr) 2014-10-29 2017-09-05 Johnson & Johnson Consumer Inc Particules de cadotril
US11103581B2 (en) 2015-08-31 2021-08-31 Acura Pharmaceuticals, Inc. Methods and compositions for self-regulated release of active pharmaceutical ingredient
JP6812104B2 (ja) * 2015-12-28 2021-01-13 エスエス製薬株式会社 経口固形組成物
US20180147153A1 (en) 2016-11-28 2018-05-31 Johnson & Johnson Consumer Inc. Process for making a coated dosage form
US10493026B2 (en) 2017-03-20 2019-12-03 Johnson & Johnson Consumer Inc. Process for making tablet using radiofrequency and lossy coated particles
WO2018217241A1 (en) 2017-05-22 2018-11-29 Johnson & Johnson Consumer Inc. Lozenge dosage form
KR20250036934A (ko) 2017-11-02 2025-03-14 바이오벤처스, 엘엘씨 개선된 근육 단백질 합성을 위한 아미노산 보충물의 이용
US11638434B2 (en) 2017-12-06 2023-05-02 Elanco Us Inc. Feed additive compositions
AU2019269739A1 (en) 2018-05-18 2020-12-10 Anavex Life Sciences Corp. Optimized sigma-1 agonist method of responder selection and treatment
WO2020073034A1 (en) * 2018-10-05 2020-04-09 Isp Investments Llc Smooth high solids film coating composition comprising water soluble cellulose ether, process for preparing the same
CA3131109A1 (en) * 2019-02-20 2020-08-27 Suntory Holdings Limited Protein-containing oral composition and method for improving flavor of protein-containing oral composition
EP4030925A4 (en) 2019-09-19 2023-10-18 Texas Tech University System MATERNAL NEONATAL PHEROMONE FOR PIGS
EP4209292A1 (fr) 2021-02-22 2023-07-12 Comadur S.A. Outil de coupe avec des orifices de lubrification de formes complexes
MX2024007416A (es) 2021-12-17 2024-07-04 Elanco Us Inc Metodos para mejorar el estado nutricional de los animales con estres inmunologico.
WO2024186730A1 (en) 2023-03-03 2024-09-12 Grads Innovation Compositions for enhanced metabolic oxidation of fatty acids
WO2024223532A1 (en) 2023-04-28 2024-10-31 Behrooz Kasraee A dietary supplement combination and use thereof for improving muscle performance

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK150008C (da) * 1981-11-20 1987-05-25 Benzon As Alfred Fremgangsmaade til fremstilling af et farmaceutisk oralt polydepotpraeparat
US4643892A (en) * 1983-07-20 1987-02-17 Warner-Lambert Company Magnesium trisilicate suitable for preparation of medicament adsorbates of analgesics
US4894233A (en) * 1984-10-05 1990-01-16 Sharma Shri C Novel drug delivery system for decongestants
IE58110B1 (en) * 1984-10-30 1993-07-14 Elan Corp Plc Controlled release powder and process for its preparation
GB8618811D0 (en) * 1986-08-01 1986-09-10 Approved Prescription Services Sustained release ibuprofen formulation
US4800087A (en) * 1986-11-24 1989-01-24 Mehta Atul M Taste-masked pharmaceutical compositions
US4835187A (en) * 1987-06-15 1989-05-30 American Home Products Corporation Spray dried ibuprofen
US4915949A (en) * 1987-07-13 1990-04-10 Alza Corporation Dispenser with movable matrix comprising a plurality of tiny pills
US4915953A (en) * 1987-09-03 1990-04-10 Alza Corporation Dosage form for delivering acetaminophen or phenylpropanolamine
US4837031A (en) * 1987-09-17 1989-06-06 Mallinckrodt, Inc. Compositions containing ibuprofen
NZ226822A (en) * 1987-11-16 1990-03-27 Mcneil Consumer Prod Chewable medicament tablet containing means for taste masking
US4851226A (en) * 1987-11-16 1989-07-25 Mcneil Consumer Products Company Chewable medicament tablet containing means for taste masking
US4835188A (en) * 1987-12-08 1989-05-30 American Home Products Corporation Spray dried ibuprofen

Also Published As

Publication number Publication date
CA2042289A1 (en) 1991-11-24
GR910100204A (el) 1992-07-30
PT97739A (pt) 1992-03-31
IE911752A1 (en) 1991-12-04
AU7723491A (en) 1991-11-28
US5075114A (en) 1991-12-24
CA2042289C (en) 1998-12-08
IE67062B1 (en) 1996-02-21
IN172428B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1993-07-24
GR1002092B (en) 1995-12-28
NZ238131A (en) 1992-09-25
JPH06316536A (ja) 1994-11-15
EP0459695A1 (en) 1991-12-04
EP0459695B1 (en) 1995-03-15
ES2073677T3 (es) 1995-08-16
PT97739B (pt) 1998-10-30
AU639334B2 (en) 1993-07-22

Similar Documents

Publication Publication Date Title
JP3157190B2 (ja) 薬剤のための味マスキング及び持効性皮膜
US11452689B2 (en) Taste-masked pharmaceutical compositions
US5489436A (en) Taste mask coatings for preparation of chewable pharmaceutical tablets
US5876759A (en) Rapidly disintegrating pharmaceutical dosage form and process for preparation thereof
US5260072A (en) Rotogranulations and taste masking coatings for preparation of chewable pharmaceutical tablets
US5529783A (en) Rotor granulation and coating of acetaminophen, pseudoephedrine, chlorpheniramine, and, optionally dextromethorphan
EP1219291B1 (en) Texture masked particles containing an active ingredient
JP3350559B2 (ja) 活性成分を含有する予め成形された微小粒子より製造される機械的に安定でかつ容易に分解し得る錠剤
JP2005516020A (ja) ゼロ次持続放出剤形およびその製造方法
IE60652B1 (en) Spray dried ibuprofen
JP2599189B2 (ja) 味覚遮蔽剤を含有している咀嚼可能な薬物錠剤
US5460825A (en) Taste mask coatings for preparing chewable pharmaceutical tablets
EP0636365A1 (en) Freeze-dried pharmaceutical dosage form and process for preparation thereof
EP0473431B1 (en) Rotogranulations and taste masking coatings for preparation of chewable pharmaceutical tablets
CA2079934C (en) Taste mask coatings for preparing chewable pharmaceutical tablets
KR100193121B1 (ko) 맛 차폐 및 서방성 약제용 피복물
MXPA01002821A (en) Multiple unit controlled food effect-independent release pharmaceutical preparations and method for preparing the same

Legal Events

Date Code Title Description
R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20080209

Year of fee payment: 7

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20090209

Year of fee payment: 8

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20100209

Year of fee payment: 9

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20100209

Year of fee payment: 9

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20110209

Year of fee payment: 10

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20120209

Year of fee payment: 11

EXPY Cancellation because of completion of term
FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20120209

Year of fee payment: 11