JP2771991B2 - 人工椎間板カプセル及びその埋め込み方法 - Google Patents

人工椎間板カプセル及びその埋め込み方法

Info

Publication number
JP2771991B2
JP2771991B2 JP63204922A JP20492288A JP2771991B2 JP 2771991 B2 JP2771991 B2 JP 2771991B2 JP 63204922 A JP63204922 A JP 63204922A JP 20492288 A JP20492288 A JP 20492288A JP 2771991 B2 JP2771991 B2 JP 2771991B2
Authority
JP
Japan
Prior art keywords
disc
artificial
artificial disc
nucleus pulposus
mantle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP63204922A
Other languages
English (en)
Other versions
JPS6470041A (en
Inventor
ディー.レイ チャールズ
ピー.コービン テリー
Original Assignee
レイメディカ,インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by レイメディカ,インコーポレイテッド filed Critical レイメディカ,インコーポレイテッド
Publication of JPS6470041A publication Critical patent/JPS6470041A/ja
Application granted granted Critical
Publication of JP2771991B2 publication Critical patent/JP2771991B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02Inorganic materials
    • A61L27/04Metals or alloys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/44Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/441Joints for the spine, e.g. vertebrae, spinal discs made of inflatable pockets or chambers filled with fluid, e.g. with hydrogel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/46Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
    • A61F2/4603Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof
    • A61F2/4611Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof of spinal prostheses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L67/00Compositions of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Compositions of derivatives of such polymers
    • C08L67/04Polyesters derived from hydroxycarboxylic acids, e.g. lactones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/3094Designing or manufacturing processes
    • A61F2/30965Reinforcing the prosthesis by embedding particles or fibres during moulding or dipping
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/44Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/442Intervertebral or spinal discs, e.g. resilient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30003Material related properties of the prosthesis or of a coating on the prosthesis
    • A61F2002/3006Properties of materials and coating materials
    • A61F2002/30062(bio)absorbable, biodegradable, bioerodable, (bio)resorbable, resorptive
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30108Shapes
    • A61F2002/30199Three-dimensional shapes
    • A61F2002/30224Three-dimensional shapes cylindrical
    • A61F2002/30235Three-dimensional shapes cylindrical tubular, e.g. sleeves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30667Features concerning an interaction with the environment or a particular use of the prosthesis
    • A61F2002/30677Means for introducing or releasing pharmaceutical products, e.g. antibiotics, into the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/44Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2002/448Joints for the spine, e.g. vertebrae, spinal discs comprising multiple adjacent spinal implants within the same intervertebral space or within the same vertebra, e.g. comprising two adjacent spinal implants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/46Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
    • A61F2/4603Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof
    • A61F2002/4625Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof with relative movement between parts of the instrument during use
    • A61F2002/4627Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof with relative movement between parts of the instrument during use with linear motion along or rotating motion about the instrument axis or the implantation direction, e.g. telescopic, along a guiding rod, screwing inside the instrument
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0004Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063Three-dimensional shapes
    • A61F2230/0069Three-dimensional shapes cylindrical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/38Materials or treatment for tissue regeneration for reconstruction of the spine, vertebrae or intervertebral discs
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S128/00Surgery
    • Y10S128/20Inflatable splint
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00Drug, bio-affecting and body treating compositions
    • Y10S424/07Microporous membranes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Transplantation (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Composite Materials (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Materials Engineering (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Prostheses (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)

Description

【発明の詳細な説明】 産業上の利用分野 本発明は人工の椎間板に関し、脊椎骨の脊髄、特に人
間の脊髄における悪化した椎間板を修復するための人工
椎間板に関する。
従来の技術 正常な椎間板は環(アニユラスanulus)と称される外
側靭帯リングを有している。この外側靭帯リングは隣接
の脊椎骨同志を互いに結合している。又、外側靭帯リン
グはコラーゲン繊維で構成されており、これらのコラー
ゲン繊維は脊椎骨に取り付いていると共に互いにクロス
されていて、脊椎骨が何れかの方向へ回転されると各個
の繊維の半分が緊張され、これによつてツイスト即ち捩
れの動きに対抗するようになされている。脊椎骨間の捩
れの動きは、更に又フアセツトジヨイントによつて制限
されるようになつている。
アニユラスの内側深くには弛緩組織で構成されている
髄核(nucleus pulposis)があり、これはツルツル且つ
又ヌルヌルしている(約85%の水分を含有している)と
共に、前後もしくは左右の曲げに際して動き回るように
なつている。従つて、曲げによつ脊椎骨の向かい合う表
面同志が互いの間の平行関係状態に変化を生じると、椎
間板の両端側の空間に生じる間隔変化(ウエツジング)
を埋め合わせるように髄核組織が動くのである。曲げに
より、アニユラスは下向きのウエツジの側では膨らみ、
上向きのウエツジの側では緊張される。
古典的な椎間板ヘルニアは、環状繊維が弱化もしくは
引き裂かれたときに生じるのであり、内側の髄核組織が
正常な環状の状態から永久的に膨らみ、膨張し、もしく
は押し出されてしまう。このような状態に於ては、脊髄
管から脚へと外方へ通じている神経をこの髄核組織(即
ち、そのままの弱まつた膨らんでいるアニユラス)が圧
迫する結果として、脚の痛みが生じるのである。
動くことのできない絶え間のない背中の痛みの主なる
原因は、変質が進んでアニユラスが慢性的な炎症を引き
起こした場合に生じるのである。環状の外側を包囲する
神経ブランチから延びた小さな神経が僅かな距離(恐ら
く6〜8mm)だけアニユラス繊維内に侵入している。ア
ニユラスの繊維層間の結合力の欠如によつて生じる該繊
維層間の規則的な異常な動きが、小さな、患部の繊維内
神経を引つ張り、或いは擦りつけるのである。このよう
にして、患部はほんのちよつとした動きに対しても敏感
になつてしまうのである。このような場合には、痛みの
激しい脊椎骨に於る椎間板の動きを機械的に制限するた
めの何等かの対策が必要となる。極めて頑固な痛みのあ
る場合には、脊椎骨同志を永久的に固定して、痛みを生
じる動きを無くすように骨を結合することが行われる。
多くの場合、僅かながら小さな動き(痛みを生じない程
度の動き)を許容することが好ましい。或る程度の動き
を保持することは、近隣の脊椎骨に於る機械的な破壊を
防止することの助けとなるのである。現在に於ては、こ
のような柔りかい結合を形成し維持することは信頼性高
く実現できてはいない。
髄核組織がヘルニア化し、或いは外科処置によつて除
去された場合は常に、椎間板の空間は挟まり、その運動
性が殆ど失われてしまう。アニユラス及び髄核に対して
回転動作が潜在的に破壊的であると考えるならば、ヘル
ニアとなつた、即ち悪化した、除去せる椎間板を何れか
の人工補綴で置き換え、これによつて回転動作は制限す
るが、曲げ、特に前後の曲げは許容するようになすべき
である。横方向の曲げはそれ程重大ではない。
これ迄一般に使用されてきた装置の何れも椎間板の空
間高さを維持し且つ脊髄骨の間の重要な動きを確保する
ものとは考えられないが、数多くの特許は人工椎間板が
この目的に有用であると記載している。例えば、米国特
許第3,875,595号明細書(フローニング)は椎間板の髄
核全体を交換する形状の人工補綴を示している。フロー
ニングによれば、「人工補綴は中空で、柔軟な袋状の部
材であり、調整可能な圧力の下で流体及び/又はプラス
チツクを充填される。この圧力は、その人工補綴が或る
期間にわたつて所定位置に配置されている間に増減され
て、試行錯誤により最適圧力を決定されるようになさ
れ、しかる後人工補綴のステムが取り除かれる。椎間板
内に通常生じる圧力の下で膨張用材料が失われてしまう
のを十分に回避できるようにして、膨張用流体又は流
体、即ち水、を保持できる特性を有するプラスチツクを
与えることによつて、この最適圧力が永久的に維持され
るのであり、膨張用材料の特性は通常の椎間板の特徴に
模したものとされる」(第1欄、第30〜43行目)。フロ
ーニングの人工補綴は、スタツド状の隆起部分を有して
おり、この隆起部分が隣の脊椎骨の骨端プレートを介し
て押し付けられたソケツト内に嵌め込まれて、人工補綴
がスリツプしないように固定されるのである。
米国特許第4,349,921号明細書(クンツ)は、高密度
ポリエチレン、ポリメタクリレート、ステンレススチー
ル、又は、クロム−コバルト合金のような生物学的に受
け入れることのできる何れかの材料で作られ、且つ又本
来の椎間板と置換される寸法形状となされた椎間板人工
補綴を示している。この人工補綴の長手方向の端部の一
方は、取り扱いを容易となすと共に、必要深さ以上に挿
入されるのを防止するように、隆起したフランジを有す
ることができる。これに対して他方の長手方向端部はウ
エツジ形状とされて挿入を容易に行えるようになされ
る。溝、皺、或いは突起のような表面の特徴を有して
「摩擦係合」を生じると共に、隣の脊椎骨の表面に応じ
た凸面を有する優劣面が備えられる。
米国特許第3,867,728号明細書(スタブスタツドその
他)は、様々な構造をした椎間板人工補綴を示してい
る。これらの人工補綴の各々は、弾性ポリマー、例えば
シリコンゴムやポリウレタンのようなエラストマーの強
化した弾性ブロツク、によって作られているコアーと、
組織が内部に侵入して成長できるような開口を有する材
料で作られた外側表面を形成するカバーと、を有してい
る。図示された殆ど全ての人工補綴は人間の椎間板の形
状とされた部材であるが、「その他の変形例として、複
数の柔軟な、弯曲した棒状の、並べて配置することによ
つて髄核を除去された本来の椎間板の内部空間を占拠で
きるような形状とされた部材、を含むことができる」
(アブストラクトに於る最後から二番目の文章)のであ
る。第23図および第24図を参照されたい。ヘルニアにな
つた椎間板を単体又は複数部材よりなる人工補綴と置き
換えるために、椎間板の空間は後方部分を露出され、そ
して、「椎間板切除術が実施されて、椎間板の空間に対
する一層良好なアクセスを得ると共に、髄核を除去し且
つ又人工補填を挿入するための開口を形成するようにな
されてる。脊髄の硬膜及び神経根が識別され、神経根は
自由状態に切り裂かれ、これらを一緒にして横方向へ引
つ込めてヘルニアを露出するようになすのである」(第
14欄、第17〜27行目)。ヘルニアになつた椎間板を完全
に切除して人工補綴を受け入れるための空間を形成した
後、「人工補綴の内方成長の表面に隣接される端部プレ
ートは弛緩組織を擦り落とされて出血面をそのままにさ
れ、内方成長する組織によつて人工補綴の固定を促進す
るようになされる」(第14欄、第35〜39行目)のであ
る。もし2部材よりなる人工補綴が使用されるならば、
「これらの2個のゼグメントをコード129で互いに縛り
付けるか、或いは隣接する一方の脊椎骨又は他方の利用
できる組織に対して縫合することができる」(第14欄、
第48〜50行目)。
脊椎骨の間に機械的に固定される椎間板の人工補綴
は、米国特許第4,554,914号(カツプその他)、第4,30
9,777号(ペーテイル)、第3,426,364号(ラム)、及
び、第4,636,217号(オギルビーその他)の明細書に示
されている。
発明の概要 本発明は、人間の椎間板の空間高さにほぼ等しい高さ
を有し、且つ又椎体のサジタル(sagittal)直径にほぼ
等しい長さを有する細長い円筒形の人工椎間板を提供す
る。その外側層すなわち外被は、組織を引き付けて内方
成長させ、ゲルコアー(gel core)を取り囲んでいる生
物学的に再吸収可能(又は、生物学的に吸収可能)な物
質を混ぜ合わされた強固で不活性な繊維で作られてい
る。ゲルコアーは、椎間板内方の髄核の本来のレオロジ
ーに似た粘性及び速度−剪断(velocity−sheer)の特
性を有する揺変性ゲルとされるのが好ましい。
この人工椎間板は対として埋込まれねばならない。こ
れらの埋込みに関する外科的処置方法は、1)損傷した
椎間板に隣接の脊椎骨をジヤツキによつて引き離し、
2)損傷した椎間板の横方向の各端部付近にサジタル穴
を間隔を隔てて形成し、そして3)各サジタル穴内に軸
線方向に細長い円筒形の人工椎間板を挿入する諸段階を
含むのである。2個のこれらの人工椎間板が損傷した椎
間板のアニユラスの髄核内に並べて挿入され、各人工椎
間板が椎間板の横方向の端部付近にそれぞれ配置される
と、これらの人工椎間板は、その高さ寸法を維持し、
又、椎間板の空間にて前後方向への曲げを含む動きを確
保するが、回転、移動を制限し、そして横方向の曲げを
僅かな程度に制限するのである。
好ましい後方からのこの外科処置は、フアセツトジヨ
イントの各々を通して11mm穴をドリル加工して窓を形成
する段階を伴うのであり、これは上述した外科的処置方
法に於る1)の段階の前又は後の何れかに行われる。し
かる後アクセスするのにこの窓を使用し、外科医は外科
的処置の2)の段階を実施して、これらの穴から破片や
損傷した椎間板の髄核のその他の望ましくない物質を除
去する。次に、段階3)に於て、人工椎間板が各窓を通
して穴内に挿入される。或る場合には、埋め込んだ人工
椎間板は椎間板高さ寸法を再確立することができ、特に
大規模にヘルニアとなつた椎間板、或いは極めて初期の
ヘルニア化の後に萎縮し続けている椎間板のような対象
に関してこれが望まれるのである。
椎間板にドリル加工して形成された穴は、隣接する脊
椎骨の端部プレートを僅かながら剥ぎ取るのに十分な大
きさとされ、これにより人工椎間板が骨及び隣接組織に
対して取り付くのを促進するようになすことが好ましい
のである。
上述した後方からの処置に於て、これらの穴は互いに
向けて真のサジタル位置から約5〜10゜だけ角度を固有
に付されており、このことはドリルバイトが椎間板の裏
側へ突き抜けることのない状態で穴を一層深く形成でき
るという利点を与えているのである。このような角度は
非常に僅かであることから、埋め込んだ人工椎間板はそ
れらの軸線、即ち細長い方向、が真のサジタル方向に位
置されているように実質的に作用するのである。
フアセツトジヨイントをドリル加工することは、前方
からの処置によつて、或いは損傷した椎間板を後方から
フアセツトジヨイントの中間にてアクセスすることによ
つて、避けることは可能である。後者の方法によれば、
動く危険を伴い、従つて脊髄神経を損傷する可能性があ
る。更に、これは椎間板に形成される穴がサジタル方向
に延在されるか、僅かにサジタル方向からずれる程度と
されて、フアセツトの窓を通してドリル加工する場合に
比較して穴の長さが短くなされることが必要である。他
方に於て、フアセツトジヨイントに対する中間的な後方
からの処置は、経皮的技術によつて実行できるのであ
り、この技術に於ては人工椎間板は最小限の破砕で所定
位置へ移動させることが可能である。
人工椎間板が皮下注射針によつてパンクされるように
設計された離れたチヤンバーに連結される場合、このチ
ヤンバーはX線蛍光制御の下に長い針で容易に到達でき
る位置に置かれなければならない。埋め込んだ人工椎間
板が椎体骨の或る程度の再モールド作用を引き起こすな
らば、空間高さが傾斜してしまい、その高さを回復させ
るために恐らく数回にわたつて再充填されることにな
る。様々な患部に対して特性の異なる揺変性ゲルが必要
とされることになり、この人工椎間板が埋め込まれた後
に該ゲルを変質させることは、袋部に対して遠隔アクセ
スできるようになすチヤンバーによつて可能とされるの
である。
袋部がチユーブによつて離れた溜槽、即ちチヤンバ
ー、に接続され、このチヤンバーが針によつてパンクさ
せることのできる自己シールメンブレンを有している場
合、その袋部は損傷された椎間板内に挿入される後迄揺
変性ゲルを充填される必要はない。損傷した椎間板内に
新規な人工椎間板が挿入された後、揺変性ゲルをチヤン
バー内に注入するのに皮下注射針が使用でき、チユーブ
を通してゲルを袋部内に押し込めて袋部を膨らませる。
この袋部はこれによりそれ自体の挿入直後に完全に充填
され、或いは椎間板の空間高さを調整し、又は少しずつ
高めるために、一度に僅かずつ充填され得るのである。
ゆつくりした椎間板の高さ修復は自然の弾性回復を許容
するのであり、これに対して、急激な上昇は椎間板のア
ニユラスを一層傷める、即ち切り裂いてしまうのであ
る。チヤンバーは、充填し過ぎと判断された場合には或
る量のゲルを抜き出すために皮下注射針を使用され得
る。
チヤンバーが柔軟な浸透性メンブレンによつて2個の
隔室に隔離されているならば、そのチヤンバーは針によ
つてパンクされる必要はない。これらの隔室の一方は袋
部と連通され且つ又揺変性ゲルを収容し、又、他方の隔
室は吸湿性材料を収容し且つ水分が浸透可能な壁部で形
成され得る。椎体の水分は吸湿性材料を徐々に膨潤さ
せ、これにより揺変性材料が徐々に気袋を充填するよう
に押し流すのである。
椎間板空間内で人工椎間板が横方向に膨らみを生じる
のを制限するために、強力な不活性繊維が外側層内に織
り込まれ、袋部を通して横方向に延在されることができ
る。このような横方向の繊維は、外側層の強力な不活性
繊維として識別されることができる。人工椎間板が離れ
たチヤンバーから更に一層充填されるならば、この横方
向繊維が先ず最初に椎間板高さの増大をもたらすのであ
る。
この新規な人工椎間板の両端は、内部圧力が脊椎骨の
荷重によつて増減する際に、裏返り、即ち捲れを生じ
て、周囲組織に圧力を伝えるように、嵌め込まれるので
ある。このことは、人工椎間板の柔軟性が構造体の弾性
的な引つ張り及び跳ね返りを必要としないようにできる
ことを意味するのである。
人工椎間板の一つがそれ自体動く傾向を示す可能性に
対抗してこれを抑制するために、各人工椎間板は挿入し
易くするが抜き出し困難、即ち自由に引き出せないよう
にするために形成されたカラー状の円周フランジを備え
ることができる。
挿入の間、もしくは埋め込んだ後に空間内で人工椎間
板が回転する可能性に対抗してこれを抑制するために、
人工椎間板は長手方向のフイン、即ちベーン、を備える
ことが好ましい。上述したような長手方向ベーン並びに
円周方向フランジの両方共、外被の繊維と同じとされ得
る強力な不活性繊維で作ることができる。
この新規な人工椎間板の外被の強力な不活性繊維、及
び該新規な人工椎間板のその他の機素の強力な不活性繊
維は、カーボン又はポリマーで作ることができるのであ
り、これらは冷間引きのポリ(エチレン テレフタレー
ト)ポリエステル繊維のような天然又は合成のポリマー
を含む。生物学的に再吸収可能な材料は、ポリ乳酸又は
ポリグリコール酸又はコラーゲン(例えば、半合成物)
とすることができるのであり、これらの各々は内方成長
組織によつて通常は置き換えられ、従つて周囲組織に対
して結合されるようになるのである。この生きている組
織による置き換えは、埋め込んだ人工補綴の永久的な柔
軟性を保証する。更に別の使用可能な生物学的に再吸収
可能な材料を記載している米国特許第4,643,734号(リ
ン)明細書を参照されたい。
生物学的に再吸収可能な材料はそれ自体が繊維質であ
り、不活性繊維と織り込まれる。他方に於て、外被、円
周フランジ、そして長手方向ベーンは、不活性繊維(生
物学的に再吸収可能な材料でコーティングされ、又は、
コーティングされない何れとすることもできる)によつ
て一緒に織ることができるのであり、しかる後に生物学
的に再吸収可能な材料を浸み込まされるのである。
埋め込んだ後、密接な繊維結合が人工椎間板の外側層
と椎体骨との間に展開される限り、椎体骨が外被に内方
成長する必要はない。外被の繊維はかなりの圧力を受け
入れできるようにするために織り上げられていることが
好ましい。
袋部は柔軟でなければならないが、弾性的である必要
はない。袋部のための好ましい材料には、方向付けされ
たポリ(エチレン テレフタレート)、高密度ポリプロ
ピレン、シリコーンゴム、そしてシリコーン及びカーボ
ンのコポリマーが含まれる。
この新規な人工椎間板が離れたチヤンバーを含む場合
には、袋部、チヤンバー及び接続チユーブは同じ材料
で、例えばブローモールド成形によつて、作られるのが
好ましい。袋部をチヤンバーと同じく自己シール材料で
作ることにより、袋部を通して横方向繊維を引つ張るた
めに、及び外被の繊維と織り合わせるために、針が使用
できるのであり、外被とその隆起部分及びフランジを同
時に織り込むのが好ましい。袋部が自己シール材料でな
い場合には、2個の半体部分に形成し、横方向繊維が所
定位置に取り付けられてこれらの横方向繊維の端部が外
被の繊維と互いに織り合わされた後、これらの半体部分
が互いにシールされるようになすのが好ましい。
揺変性ゲルは、無機質オイル(例えば、シリコーンや
フルオロカーボン)、及び、フエーム化されたシリカの
ようなゲル化剤(混合物の約3〜10重量%であり、6rpm
にて100〜10000cpsの間のブルツクフイールド粘度を与
えるのが好ましい)の混合物とされる。このゲルの粘度
は、制限された動きに際して、椎間板空間に於る曲げの
間に、特にゆつくりした姿勢の変化の間に、通常の迅速
性を有して運動できるように選定される。「Cab−O−S
ilの特性及び機能」と題されたカボツトコーポレーシヨ
ンによるブリテン(9/83の日付)は第10頁にて、「Cab
−O−Sil」のヒユーム化されたシリカは、製薬製品を
内服又は局部的に適用するために使用することが食品及
び薬品局(F.D.A.)によつて認知されたことを記載して
いる。
好ましい実施例の説明 第1図に示された細長い人工椎間板10は外被12を有し
ており、この外被12は、組織を引き付けて内方成長させ
る生物学的な再吸収可能な繊維と互いに織り合わされて
いる強力な不活性ポリマー繊維のネツト網として構成さ
れている。これらの繊維は又、2個の円周バンド、即ち
フランジ14、及び長手方向フイン、即ちベーン16、を形
成するように配置された強力な不活性ポリマー繊維が織
り合わされており、これらのフランジ及びベーンは外被
12の外面に突き出して形成されている。
外被12は袋部18を取り囲んでおり、この袋部は第2図
に示すように揺変性ゲル20を収容している。小さなチユ
ーブ22がこの袋部を小さな離れたチヤンバー24に接続し
ており、このチヤンバーは針でパンクさせることができ
る自己シールメンブレンによつて構成されている。人工
椎間板10が第4図及び第5図に示すように人間の脊髄内
に埋め込まれた後、チユーブ22はチヤンバー24が第4図
に示すように位置されることを可能にし、こにより揺変
性ゲルは皮下注射針を脊髄領域に差し込むことなく挿入
することでチヤンバーに追加又は抜き出しできるのであ
る。
埋め込む領域は、L4及びL5の脊椎骨の間の悪化した、
即ちヘルニアとなつた椎間板26の部分である。第3図に
見られるように、窓28及び28aがフアセツト30及び30aの
下部にドリル加工して形成されている。これらの窓を利
用して、一対の穴31及び31aの椎間板26内にドリル加工
されて形成されるのであり、各穴は損傷された椎間板26
の横方向の端部付近に形成され、且つ又、他方の穴に向
けてサジタル方向から約10゜だけ角度を付されている。
又これらの窓を使用して、ドリル加工による破片や、椎
間板の髄核の存在し得るその他の部分が除去される。こ
の除去の後、人工椎間板10及びこれと同じ人工椎間板10
aがそれぞれ穴31及び31a内に脊髄神経を乱すことなく軸
線方向に沿つて挿入される。
第4図に見られるように、人工椎間板10及び10aが穴3
1及び31a内に挿入されると、これらの人工椎間板は並ん
で且つ間隔を隔てて位置されるのであり、各人工椎間板
の細長い方向、即ち軸線、はサジタル方向に対して約10
゜の角度を付されて延在される。第5図は、人工椎間板
10及び10aが脊椎骨L4及びL5の間の高さ及び空間を修復
したことを示しており、椎間板26のアニユラスは緊密状
態とされている。これにより、椎間板空間の潰れ及び弱
つたアニユラスの膨れの組み合わせによつて生じた神経
に対する圧迫が解放されるのである。
再び第2図を参照すれば、多数のポリマー繊維又はそ
の他の強力な不活性繊維32が人工椎間板10の赤道を横方
向に横断して延在されており、これらの繊維は外被12の
繊維と織り合わされている。このような横方向の繊維32
の存在によつて、人工椎間板10は患部の脊髄の垂直方向
の圧力によつてフラツト形状となるのを防止され、これ
により患つている脊椎骨L4多びL5の間の空間を維持する
のである。この間隔内に人工椎間板10及び10aが埋め込
まれるのである。長手方向ベーン16及び16aは人工椎間
板が回転するのを防止するように作用する。一方、円周
フランジ14及び14aは人工椎間板を脊椎骨の間の空間内
に良好に固定するように作用するのである。
【図面の簡単な説明】
第1図は、人工椎間板を一層膨らませたりしぼめたりす
るための離れたチヤンバーを有している、本発明の好ま
しい細長い人工椎間板の斜視図。 第2図は、第1図の線2−2に沿う拡大した中央断面
図。 第3図は、第1図及び第2図に示した人工椎間板の対を
L4及びL5の脊椎骨の間の変質した椎間板内に埋め込むた
めに都合良いアクセスを得るように、フアセツトの下部
を通してドリル加工して形成された2個の窓を示す、人
間の脊髄の後方視図。 第4図は、L4の脊椎骨が省略された状態での第3図に与
えられた脊髄の横断面図。 第5図は、寸法を縮小した第4図の線5−5に沿う断面
図。 L4,L5……脊椎骨、10,10a……人工椎間板、12……外
被、14,14a……円周フランジ、16,16a……長手方向ベー
ン、18……袋部、20……揺変性ゲル、22……チユーブ、
24……チヤンバー、26……椎間板、32……不活性繊維。

Claims (8)

    (57)【特許請求の範囲】
  1. 【請求項1】損傷した椎間板の髄核内にサジタル方向に
    挿入されるようになされた細長い円筒形の人工椎間板で
    あって、特に、前記人工椎間板の空間高さにほぼ等しい
    高さを有すると共に、該椎間板の髄核のサジタル直径に
    ほぼ等しい長さを有しており、この人工椎間板が、組織
    を引き付けて内方成長させる生物学的な再吸収可能な材
    料と混合された強力な不活性繊維の外被と、ゲルコアー
    とを有して構成されていて、このような2個の人工椎間
    板が損傷した椎間板のアニュラス髄核内部に並べて挿入
    されて、各々が椎間板の横方向端部付近にそれぞれ位置
    され且つ又互いの人工椎間板から間隔を隔てて位置され
    たときに、これらの人工椎間板が、椎間板の空間に於
    て、高さ寸法を維持し且つ又前後の曲げを含む動きは確
    保するが、回転は制限するようになることを特徴とする
    人工椎間板。
  2. 【請求項2】前記ゲルコアーが、椎間板の髄核組織の本
    来のレオロジーを模した粘性及び速度−剪断の特性を有
    する揺変性ゲルとされたことを特徴とする特許請求の範
    囲第1項に記載の人工椎間板。
  3. 【請求項3】椎間板の空間内で人工椎間板が回転するの
    を防止するために、外被の外側部に外部隆起部分、即ち
    長手方向ベーンが取り付けられていることを特徴とする
    特許請求の範囲第1項に記載の人工椎間板。
  4. 【請求項4】外被が、前記不活性繊維と織り合わされて
    いる繊維を備える生物学的に再吸収可能な材料を含むこ
    とを特徴とする特許請求の範囲第1項に記載の人工椎間
    板。
  5. 【請求項5】生物学的に再吸収可能な材料が前記外被の
    上にコーティングされていることを特徴とする特許請求
    の範囲第1項に記載の人工椎間板。
  6. 【請求項6】前記生物学的に再吸収可能な材料がポリ乳
    酸、ポリグリコール酸及びコラーゲンから選定されてい
    ることを特徴とする特許請求の範囲第1項に記載の人工
    椎間板。
  7. 【請求項7】内部のゲルコアーと中空のチューブによっ
    て連通されている外部のチヤンバーが、針でパンクさせ
    ることができる自己シールメンブレンで作られているこ
    とを特徴とする特許請求の範囲第1項に記載の人工椎間
    板。
  8. 【請求項8】損傷した椎間板の髄核内にサジタル方向へ
    挿入されているようになされた細長い円筒形の人工椎間
    板であって、この人工椎間板が、椎間板の髄核組織の本
    来のレオロジーを模したゲルコアーと、該ゲルコアーを
    囲んだ外部層で、該椎間板の髄核のサジタル直径にほぼ
    等しい長さと、その長さより小さい幅と、その長さより
    小さい高さを備えた外部層とを含んでいることを特徴と
    する人工椎間板。
JP63204922A 1987-08-20 1988-08-19 人工椎間板カプセル及びその埋め込み方法 Expired - Fee Related JP2771991B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US07/087,424 US4772287A (en) 1987-08-20 1987-08-20 Prosthetic disc and method of implanting
US087424 1987-08-20
US07/223,400 US4904260A (en) 1987-08-20 1988-07-25 Prosthetic disc containing therapeutic material

Publications (2)

Publication Number Publication Date
JPS6470041A JPS6470041A (en) 1989-03-15
JP2771991B2 true JP2771991B2 (ja) 1998-07-02

Family

ID=26776962

Family Applications (2)

Application Number Title Priority Date Filing Date
JP63204922A Expired - Fee Related JP2771991B2 (ja) 1987-08-20 1988-08-19 人工椎間板カプセル及びその埋め込み方法
JP1191230A Pending JPH02111359A (ja) 1987-08-20 1989-07-24 治療用物質を含むプロテーゼの円板

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP1191230A Pending JPH02111359A (ja) 1987-08-20 1989-07-24 治療用物質を含むプロテーゼの円板

Country Status (4)

Country Link
US (2) US4772287A (ja)
EP (2) EP0304305B1 (ja)
JP (2) JP2771991B2 (ja)
CA (1) CA1324864C (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007530120A (ja) * 2004-03-26 2007-11-01 ヌヴァシヴ インコーポレイテッド 脊椎円板髄核置換用多孔質インプラント

Families Citing this family (787)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH671691A5 (ja) * 1987-01-08 1989-09-29 Sulzer Ag
US5258043A (en) * 1987-07-20 1993-11-02 Regen Corporation Method for making a prosthetic intervertebral disc
US5108438A (en) * 1989-03-02 1992-04-28 Regen Corporation Prosthetic intervertebral disc
US4772287A (en) * 1987-08-20 1988-09-20 Cedar Surgical, Inc. Prosthetic disc and method of implanting
US5282856A (en) * 1987-12-22 1994-02-01 Ledergerber Walter J Implantable prosthetic device
DE8807485U1 (de) * 1988-06-06 1989-08-10 Mecron Medizinische Produkte Gmbh, 1000 Berlin Endoprothese der Zwischenwirbelscheibe
US6210412B1 (en) 1988-06-13 2001-04-03 Gary Karlin Michelson Method for inserting frusto-conical interbody spinal fusion implants
US6923810B1 (en) * 1988-06-13 2005-08-02 Gary Karlin Michelson Frusto-conical interbody spinal fusion implants
US7491205B1 (en) 1988-06-13 2009-02-17 Warsaw Orthopedic, Inc. Instrumentation for the surgical correction of human thoracic and lumbar spinal disease from the lateral aspect of the spine
US6123705A (en) 1988-06-13 2000-09-26 Sdgi Holdings, Inc. Interbody spinal fusion implants
US7452359B1 (en) * 1988-06-13 2008-11-18 Warsaw Orthopedic, Inc. Apparatus for inserting spinal implants
US7534254B1 (en) 1988-06-13 2009-05-19 Warsaw Orthopedic, Inc. Threaded frusto-conical interbody spinal fusion implants
US6120502A (en) 1988-06-13 2000-09-19 Michelson; Gary Karlin Apparatus and method for the delivery of electrical current for interbody spinal arthrodesis
US6770074B2 (en) 1988-06-13 2004-08-03 Gary Karlin Michelson Apparatus for use in inserting spinal implants
US5484437A (en) 1988-06-13 1996-01-16 Michelson; Gary K. Apparatus and method of inserting spinal implants
US7431722B1 (en) * 1995-02-27 2008-10-07 Warsaw Orthopedic, Inc. Apparatus including a guard member having a passage with a non-circular cross section for providing protected access to the spine
US5772661A (en) 1988-06-13 1998-06-30 Michelson; Gary Karlin Methods and instrumentation for the surgical correction of human thoracic and lumbar spinal disease from the antero-lateral aspect of the spine
AU7139994A (en) 1988-06-13 1995-01-03 Karlin Technology, Inc. Apparatus and method of inserting spinal implants
FR2639823A1 (fr) * 1988-12-06 1990-06-08 Garcia Alain Remplacement du nucleus du disque intervertebral par un polyurethane polymerise in situ
US4969888A (en) * 1989-02-09 1990-11-13 Arie Scholten Surgical protocol for fixation of osteoporotic bone using inflatable device
WO1990012611A1 (en) * 1989-04-21 1990-11-01 Ash Medical Systems, Inc. Non-intravascular infusion access device
CA2007210C (en) * 1989-05-10 1996-07-09 Stephen D. Kuslich Intervertebral reamer
US5015255A (en) * 1989-05-10 1991-05-14 Spine-Tech, Inc. Spinal stabilization method
US5895427A (en) * 1989-07-06 1999-04-20 Sulzer Spine-Tech Inc. Method for spinal fixation
DE3922203C1 (de) * 1989-07-06 1990-10-25 Martin Nolde Chirurgisches Instrument zur Implantation einer Bandscheibenkernprothese
US5458638A (en) * 1989-07-06 1995-10-17 Spine-Tech, Inc. Non-threaded spinal implant
DE3927001A1 (de) * 1989-08-16 1991-02-21 Lucien C Dr Med Olivier Kathetersystem
US5059193A (en) * 1989-11-20 1991-10-22 Spine-Tech, Inc. Expandable spinal implant and surgical method
US5269770A (en) * 1990-01-10 1993-12-14 Rochester Medical Corporation Microcidal agent releasing catheter with balloon
US5261896A (en) 1990-01-10 1993-11-16 Rochester Medical Corporation Sustained release bactericidal cannula
US5971954A (en) 1990-01-10 1999-10-26 Rochester Medical Corporation Method of making catheter
US6626888B1 (en) 1990-01-10 2003-09-30 Rochester Medical Corporation Method of shaping structures with an overcoat layer including female urinary catheter
US5098379A (en) * 1990-01-10 1992-03-24 Rochester Medical Corporation Catheter having lubricated outer sleeve and methods for making and using same
US5360402A (en) * 1990-01-10 1994-11-01 Rochester Medical Corporation Hand-actuated retention catheter
US5670111A (en) * 1990-01-10 1997-09-23 Rochester Medical Corporation Method of shaping structures with an overcoat layer including female urinary catheter
DE4003029A1 (de) * 1990-02-02 1991-08-08 Bosch Gmbh Robert Handgefuehrte werkzeugmaschine mit radialgeblaese
US5236563A (en) * 1990-06-18 1993-08-17 Advanced Surface Technology Inc. Surface-modified bioabsorbables
US5192326A (en) * 1990-12-21 1993-03-09 Pfizer Hospital Products Group, Inc. Hydrogel bead intervertebral disc nucleus
US5047055A (en) * 1990-12-21 1991-09-10 Pfizer Hospital Products Group, Inc. Hydrogel intervertebral disc nucleus
US5390683A (en) * 1991-02-22 1995-02-21 Pisharodi; Madhavan Spinal implantation methods utilizing a middle expandable implant
WO1992014423A1 (en) * 1991-02-22 1992-09-03 Pisharodi Madhavan Middle expandable intervertebral disk implant and method
US5171278A (en) * 1991-02-22 1992-12-15 Madhavan Pisharodi Middle expandable intervertebral disk implants
US5123926A (en) * 1991-02-22 1992-06-23 Madhavan Pisharodi Artificial spinal prosthesis
FR2674743B1 (fr) * 1991-04-03 1999-01-15 Bouvet Jean Claude Prothese medicale pour articulation.
US5176683A (en) * 1991-04-22 1993-01-05 Kimsey Timothy P Prosthesis press and method of using the same
US5219360A (en) * 1991-05-10 1993-06-15 Fortis Research Corporation Mammary prosthesis fill and method of making same
US5306307A (en) * 1991-07-22 1994-04-26 Calcitek, Inc. Spinal disk implant
US5171279A (en) * 1992-03-17 1992-12-15 Danek Medical Method for subcutaneous suprafascial pedicular internal fixation
US5282857A (en) * 1992-04-13 1994-02-01 Perry Larry C Gel-filled implants
US5391203A (en) * 1992-04-13 1995-02-21 Scott P. Bartlett Method of draining and filling soft tissue implant
US5306309A (en) * 1992-05-04 1994-04-26 Calcitek, Inc. Spinal disk implant and implantation kit
US5344451A (en) * 1992-06-24 1994-09-06 Dayton Michael P Synthetic reconstructive implant device
BR9307470A (pt) * 1992-11-18 1999-06-01 Lipomatrix Inc Implante
US5725577A (en) * 1993-01-13 1998-03-10 Saxon; Allen Prosthesis for the repair of soft tissue defects
ES2141217T3 (es) * 1993-02-10 2000-03-16 Sulzer Spine Tech Inc Juego de herramientas quirurgicas para estabilizacion de la columna vertebral.
US5534028A (en) * 1993-04-20 1996-07-09 Howmedica, Inc. Hydrogel intervertebral disc nucleus with diminished lateral bulging
EP0621020A1 (de) * 1993-04-21 1994-10-26 SULZER Medizinaltechnik AG Zwischenwirbelprothese und Verfahren zum Implantieren einer derartigen Prothese
EP1508307A1 (en) * 1993-06-10 2005-02-23 Karlin Technology, Inc. Bone cutting device
DE4417629B4 (de) * 1993-06-24 2006-03-16 SDGI Holdings, Inc., Wilmington Implantat für den Ersatz von Wirbelkörpern
FR2707480B1 (fr) * 1993-06-28 1995-10-20 Bisserie Michel Prothèse discale intervertébrale.
BE1007549A3 (nl) * 1993-09-21 1995-08-01 Beckers Louis Francois Charles Implantaat.
US5397364A (en) * 1993-10-12 1995-03-14 Danek Medical, Inc. Anterior interbody fusion device
JP3333211B2 (ja) * 1994-01-26 2002-10-15 レイリー,マーク・エイ 骨の治療に関する外科的方法で使用される、改良に係る拡張可能な装置
US7044954B2 (en) * 1994-01-26 2006-05-16 Kyphon Inc. Method for treating a vertebral body
DE69535492T2 (de) * 1994-01-26 2007-09-06 Kyphon Inc., Sunnyvale Verbesserte aufblasbare Vorrichtung zur Verwendung in chirurgischen Methoden zur Fixierung von Knochen
US6248110B1 (en) * 1994-01-26 2001-06-19 Kyphon, Inc. Systems and methods for treating fractured or diseased bone using expandable bodies
US6241734B1 (en) * 1998-08-14 2001-06-05 Kyphon, Inc. Systems and methods for placing materials into bone
US20030229372A1 (en) * 1994-01-26 2003-12-11 Kyphon Inc. Inflatable device for use in surgical protocols relating to treatment of fractured or diseased bone
US20060100635A1 (en) * 1994-01-26 2006-05-11 Kyphon, Inc. Inflatable device for use in surgical protocol relating to fixation of bone
US5888220A (en) * 1994-05-06 1999-03-30 Advanced Bio Surfaces, Inc. Articulating joint repair
US20050043808A1 (en) * 1994-05-06 2005-02-24 Advanced Bio Surfaces, Inc. Knee joint prosthesis
WO1998020939A2 (en) 1996-11-15 1998-05-22 Advanced Bio Surfaces, Inc. Biomaterial system for in situ tissue repair
US6248131B1 (en) 1994-05-06 2001-06-19 Advanced Bio Surfaces, Inc. Articulating joint repair
US5556429A (en) * 1994-05-06 1996-09-17 Advanced Bio Surfaces, Inc. Joint resurfacing system
US5571189A (en) * 1994-05-20 1996-11-05 Kuslich; Stephen D. Expandable fabric implant for stabilizing the spinal motion segment
AU2621295A (en) * 1994-05-24 1995-12-18 Smith & Nephew Plc Intervertebral disc implant
US6290723B1 (en) 1994-06-14 2001-09-18 Winston A. Andrews Method of making a synthetic triglyceride filler material
FR2722397A1 (fr) * 1994-07-12 1996-01-19 Laboratoire Perouse Implant Prothese interne et dispositif prothetique correspondant
FR2723841B1 (fr) * 1994-08-23 1998-11-06 Fabien Gauchet Prothese de disque intervertebral.
ATE203885T1 (de) * 1994-09-08 2001-08-15 Stryker Technologies Corp Bandscheibenkern aus hydrogel
EP0781113B1 (en) * 1994-09-15 2002-03-27 Surgical Dynamics, Inc. Conically-shaped anterior fusion cage
US5885299A (en) * 1994-09-15 1999-03-23 Surgical Dynamics, Inc. Apparatus and method for implant insertion
WO1996011642A1 (en) * 1994-10-17 1996-04-25 Raymedica, Inc. Prosthetic spinal disc nucleus
US5824093A (en) * 1994-10-17 1998-10-20 Raymedica, Inc. Prosthetic spinal disc nucleus
US5562736A (en) * 1994-10-17 1996-10-08 Raymedica, Inc. Method for surgical implantation of a prosthetic spinal disc nucleus
US5674296A (en) 1994-11-14 1997-10-07 Spinal Dynamics Corporation Human spinal disc prosthesis
FR2728159B1 (fr) * 1994-12-16 1997-06-27 Tornier Sa Prothese discale elastique
US6758849B1 (en) 1995-02-17 2004-07-06 Sdgi Holdings, Inc. Interbody spinal fusion implants
US5782919A (en) 1995-03-27 1998-07-21 Sdgi Holdings, Inc. Interbody fusion device and method for restoration of normal spinal anatomy
EP0888099B1 (en) * 1995-03-27 2005-01-12 SDGI Holdings, Inc. Spinal fusion implants and tools for insertion and revision
US6206922B1 (en) 1995-03-27 2001-03-27 Sdgi Holdings, Inc. Methods and instruments for interbody fusion
US5645549A (en) * 1995-04-24 1997-07-08 Danek Medical, Inc. Template for positioning interbody fusion devices
US5785707A (en) * 1995-04-24 1998-07-28 Sdgi Holdings, Inc. Template for positioning interbody fusion devices
US20050131267A1 (en) * 1995-06-07 2005-06-16 Talmadge Karen D. System and method for delivering a therapeutic agent for bone disease
US20050131269A1 (en) * 1995-06-07 2005-06-16 Talmadge Karen D. System and method for delivering a therapeutic agent for bone disease
US6669685B1 (en) * 1997-11-06 2003-12-30 Biolase Technology, Inc. Tissue remover and method
US5989289A (en) 1995-10-16 1999-11-23 Sdgi Holdings, Inc. Bone grafts
US6423095B1 (en) * 1995-10-16 2002-07-23 Sdgi Holdings, Inc. Intervertebral spacers
US5645597A (en) * 1995-12-29 1997-07-08 Krapiva; Pavel I. Disc replacement method and apparatus
WO1997037619A1 (de) * 1996-04-10 1997-10-16 Synthes Ag Chur Zwischenwirbel-implantat
US5700264A (en) * 1996-07-01 1997-12-23 Zucherman; James F. Apparatus and method for preparing a site for an interbody fusion implant
US5964807A (en) 1996-08-08 1999-10-12 Trustees Of The University Of Pennsylvania Compositions and methods for intervertebral disc reformation
US5895426A (en) 1996-09-06 1999-04-20 Osteotech, Inc. Fusion implant device and method of use
US5782832A (en) * 1996-10-01 1998-07-21 Surgical Dynamics, Inc. Spinal fusion implant and method of insertion thereof
US6063088A (en) * 1997-03-24 2000-05-16 United States Surgical Corporation Method and instrumentation for implant insertion
US5968098A (en) * 1996-10-22 1999-10-19 Surgical Dynamics, Inc. Apparatus for fusing adjacent bone structures
US20050165483A1 (en) * 2004-01-27 2005-07-28 Ray Eddie F.Iii Bone grafts
EP1438935A3 (en) * 1996-10-23 2005-03-02 SDGI Holdings, Inc. Spinal spacer
US6190414B1 (en) 1996-10-31 2001-02-20 Surgical Dynamics Inc. Apparatus for fusion of adjacent bone structures
US6068630A (en) 1997-01-02 2000-05-30 St. Francis Medical Technologies, Inc. Spine distraction implant
US6156038A (en) * 1997-01-02 2000-12-05 St. Francis Medical Technologies, Inc. Spine distraction implant and method
US7201751B2 (en) 1997-01-02 2007-04-10 St. Francis Medical Technologies, Inc. Supplemental spine fixation device
US6902566B2 (en) * 1997-01-02 2005-06-07 St. Francis Medical Technologies, Inc. Spinal implants, insertion instruments, and methods of use
US6451019B1 (en) 1998-10-20 2002-09-17 St. Francis Medical Technologies, Inc. Supplemental spine fixation device and method
US5860977A (en) 1997-01-02 1999-01-19 Saint Francis Medical Technologies, Llc Spine distraction implant and method
US5836948A (en) 1997-01-02 1998-11-17 Saint Francis Medical Technologies, Llc Spine distraction implant and method
US6695842B2 (en) 1997-10-27 2004-02-24 St. Francis Medical Technologies, Inc. Interspinous process distraction system and method with positionable wing and method
US6514256B2 (en) 1997-01-02 2003-02-04 St. Francis Medical Technologies, Inc. Spine distraction implant and method
US7101375B2 (en) * 1997-01-02 2006-09-05 St. Francis Medical Technologies, Inc. Spine distraction implant
US20020143331A1 (en) * 1998-10-20 2002-10-03 Zucherman James F. Inter-spinous process implant and method with deformable spacer
US7306628B2 (en) * 2002-10-29 2007-12-11 St. Francis Medical Technologies Interspinous process apparatus and method with a selectably expandable spacer
US6712819B2 (en) 1998-10-20 2004-03-30 St. Francis Medical Technologies, Inc. Mating insertion instruments for spinal implants and methods of use
US7959652B2 (en) 2005-04-18 2011-06-14 Kyphon Sarl Interspinous process implant having deployable wings and method of implantation
US5749916A (en) * 1997-01-21 1998-05-12 Spinal Innovations Fusion implant
US6039761A (en) * 1997-02-12 2000-03-21 Li Medical Technologies, Inc. Intervertebral spacer and tool and method for emplacement thereof
IL128261A0 (en) 1999-01-27 1999-11-30 Disc O Tech Medical Tech Ltd Expandable element
ATE384477T1 (de) 1997-03-07 2008-02-15 Disc O Tech Medical Tech Ltd Systeme zur perkutanen knochen und wirbelstabilisirung,befestigung und reparatur
US5876457A (en) * 1997-05-20 1999-03-02 George J. Picha Spinal implant
US6022376A (en) * 1997-06-06 2000-02-08 Raymedica, Inc. Percutaneous prosthetic spinal disc nucleus and method of manufacture
GB9713330D0 (en) * 1997-06-25 1997-08-27 Bridport Gundry Plc Surgical implant
US6241771B1 (en) 1997-08-13 2001-06-05 Cambridge Scientific, Inc. Resorbable interbody spinal fusion devices
ATE220564T1 (de) * 1997-08-14 2002-08-15 Sulzer Innotec Ag Zusammensetzung und vorrichtung zur reparatur von knorpelgewebe in vivo bestehend aus nanokapseln mit osteoinduktiven und/oder chondroinduktiven faktoren
AT405237B (de) 1997-08-28 1999-06-25 Ronald J Dr Sabitzer Wirbelsäulen-prothese
US6977095B1 (en) * 1997-10-01 2005-12-20 Wright Medical Technology Inc. Process for producing rigid reticulated articles
KR100779258B1 (ko) 1997-10-27 2007-11-27 세인트 프랜시스 메디컬 테크놀로지스, 인코포레이티드 척추 신연 삽입물
DE69838848T2 (de) * 1997-10-27 2008-12-11 St. Francis Medical Technologies, Inc., Alameda Wirbelsäulen distraktionsimplantat
US5932552A (en) 1997-11-26 1999-08-03 Keraplast Technologies Ltd. Keratin-based hydrogel for biomedical applications and method of production
WO1999029246A1 (en) * 1997-12-08 1999-06-17 Kyphon Inc. Systems and methods using expandable bodies to push apart cortical bone surfaces
WO1999053871A1 (en) 1998-04-23 1999-10-28 Cauthen Research Group, Inc. Articulating spinal implant
US6679915B1 (en) 1998-04-23 2004-01-20 Sdgi Holdings, Inc. Articulating spinal implant
US6019792A (en) * 1998-04-23 2000-02-01 Cauthen Research Group, Inc. Articulating spinal implant
ES2354492T3 (es) * 1998-06-01 2011-03-15 Kyphon Sarl Estructuras preformadas expandibles para el despliegue en regiones corporales internas.
US6132465A (en) * 1998-06-04 2000-10-17 Raymedica, Inc. Tapered prosthetic spinal disc nucleus
US6086593A (en) 1998-06-30 2000-07-11 Bonutti; Peter M. Method and apparatus for use in operating on a bone
AU4864199A (en) 1998-07-07 2000-01-24 Sdgi Holdings, Inc. Template for positioning interbody fusion devices
JP2002521090A (ja) 1998-07-22 2002-07-16 スパイナル ダイナミックス コーポレイション 複数の円板状部材を用いる単一または複数列のネジ切り式円筒形椎間板プロテーゼ
US6099531A (en) * 1998-08-20 2000-08-08 Bonutti; Peter M. Changing relationship between bones
JP2002524141A (ja) * 1998-09-04 2002-08-06 スパイナル ダイナミックス コーポレイション 複数の円板を含むピーナッツ眼鏡形胸腰部椎間板プロテーゼ
US6132468A (en) * 1998-09-10 2000-10-17 Mansmann; Kevin A. Arthroscopic replacement of cartilage using flexible inflatable envelopes
US7189234B2 (en) 1998-10-20 2007-03-13 St. Francis Medical Technologies, Inc. Interspinous process implant sizer and distractor with a split head and size indicator and method
US6652534B2 (en) 1998-10-20 2003-11-25 St. Francis Medical Technologies, Inc. Apparatus and method for determining implant size
US7029473B2 (en) * 1998-10-20 2006-04-18 St. Francis Medical Technologies, Inc. Deflectable spacer for use as an interspinous process implant and method
US6652527B2 (en) 1998-10-20 2003-11-25 St. Francis Medical Technologies, Inc. Supplemental spine fixation device and method
US7621950B1 (en) 1999-01-27 2009-11-24 Kyphon Sarl Expandable intervertebral spacer
US6325827B1 (en) 1999-02-01 2001-12-04 Blacksheep Technologies, Inc. Intervertebral implant
US6746485B1 (en) 1999-02-18 2004-06-08 St. Francis Medical Technologies, Inc. Hair used as a biologic disk, replacement, and/or structure and method
US6436143B1 (en) * 1999-02-22 2002-08-20 Anthony C. Ross Method and apparatus for treating intervertebral disks
CA2594492A1 (en) * 1999-03-07 2000-09-14 Active Implants Corporation Method and apparatus for computerized surgery
US6113639A (en) * 1999-03-23 2000-09-05 Raymedica, Inc. Trial implant and trial implant kit for evaluating an intradiscal space
US6602291B1 (en) 1999-04-05 2003-08-05 Raymedica, Inc. Prosthetic spinal disc nucleus having a shape change characteristic
US6783545B2 (en) * 1999-04-07 2004-08-31 Howmedica Osteonica Corp. Low profile fusion cage and insertion set
US6110210A (en) * 1999-04-08 2000-08-29 Raymedica, Inc. Prosthetic spinal disc nucleus having selectively coupled bodies
US7094239B1 (en) * 1999-05-05 2006-08-22 Sdgi Holdings, Inc. Screws of cortical bone and method of manufacture thereof
US6419704B1 (en) * 1999-10-08 2002-07-16 Bret Ferree Artificial intervertebral disc replacement methods and apparatus
US20060247665A1 (en) * 1999-05-28 2006-11-02 Ferree Bret A Methods and apparatus for treating disc herniation and preventing the extrusion of interbody bone graft
US6245107B1 (en) 1999-05-28 2001-06-12 Bret A. Ferree Methods and apparatus for treating disc herniation
US7273497B2 (en) 1999-05-28 2007-09-25 Anova Corp. Methods for treating a defect in the annulus fibrosis
US6969404B2 (en) * 1999-10-08 2005-11-29 Ferree Bret A Annulus fibrosis augmentation methods and apparatus
US20070038231A1 (en) 1999-05-28 2007-02-15 Ferree Bret A Methods and apparatus for treating disc herniation and preventing the extrusion of interbody bone graft
AU770261B2 (en) 1999-06-04 2004-02-19 Warsaw Orthopedic, Inc. Artificial disc implant
US6685695B2 (en) * 1999-08-13 2004-02-03 Bret A. Ferree Method and apparatus for providing nutrition to intervertebral disc tissue
US6755863B2 (en) * 1999-10-08 2004-06-29 Bret A. Ferree Rotator cuff repair using engineered tissues
US7435260B2 (en) * 1999-08-13 2008-10-14 Ferree Bret A Use of morphogenetic proteins to treat human disc disease
US6454804B1 (en) 1999-10-08 2002-09-24 Bret A. Ferree Engineered tissue annulus fibrosis augmentation methods and apparatus
US6793677B2 (en) * 1999-08-13 2004-09-21 Bret A. Ferree Method of providing cells and other biologic materials for transplantation
US7201776B2 (en) * 1999-10-08 2007-04-10 Ferree Bret A Artificial intervertebral disc replacements with endplates
US7553329B2 (en) * 1999-08-18 2009-06-30 Intrinsic Therapeutics, Inc. Stabilized intervertebral disc barrier
US7507243B2 (en) 1999-08-18 2009-03-24 Gregory Lambrecht Devices and method for augmenting a vertebral disc
US7717961B2 (en) 1999-08-18 2010-05-18 Intrinsic Therapeutics, Inc. Apparatus delivery in an intervertebral disc
US6425919B1 (en) 1999-08-18 2002-07-30 Intrinsic Orthopedics, Inc. Devices and methods of vertebral disc augmentation
US7972337B2 (en) 2005-12-28 2011-07-05 Intrinsic Therapeutics, Inc. Devices and methods for bone anchoring
US7998213B2 (en) * 1999-08-18 2011-08-16 Intrinsic Therapeutics, Inc. Intervertebral disc herniation repair
US7094258B2 (en) 1999-08-18 2006-08-22 Intrinsic Therapeutics, Inc. Methods of reinforcing an annulus fibrosis
US6936072B2 (en) * 1999-08-18 2005-08-30 Intrinsic Therapeutics, Inc. Encapsulated intervertebral disc prosthesis and methods of manufacture
EP1624832A4 (en) 1999-08-18 2008-12-24 Intrinsic Therapeutics Inc DEVICES AND METHOD FOR AUGMENTING A WINDOW NUCLEUS
US6821276B2 (en) * 1999-08-18 2004-11-23 Intrinsic Therapeutics, Inc. Intervertebral diagnostic and manipulation device
US8323341B2 (en) 2007-09-07 2012-12-04 Intrinsic Therapeutics, Inc. Impaction grafting for vertebral fusion
MXPA03003600A (es) 1999-08-18 2004-12-02 Intrinsic Orthopedics Inc Dispositivos y metodo para aumentar y retener nucleo pulposo.
US20040044412A1 (en) * 1999-08-18 2004-03-04 Gregory Lambrecht Devices and method for augmenting a vertebral disc
US6371984B1 (en) 1999-09-13 2002-04-16 Keraplast Technologies, Ltd. Implantable prosthetic or tissue expanding device
US6783546B2 (en) 1999-09-13 2004-08-31 Keraplast Technologies, Ltd. Implantable prosthetic or tissue expanding device
US6436119B1 (en) 1999-09-30 2002-08-20 Raymedica, Inc. Adjustable surgical dilator
US6264695B1 (en) 1999-09-30 2001-07-24 Replication Medical, Inc. Spinal nucleus implant
US20040186573A1 (en) * 1999-10-08 2004-09-23 Ferree Bret A. Annulus fibrosis augmentation methods and apparatus
US20030004574A1 (en) * 1999-10-08 2003-01-02 Ferree Bret A. Disc and annulus augmentation using biologic tissue
US6648920B2 (en) * 1999-10-08 2003-11-18 Bret A. Ferree Natural and synthetic supplements to engineered annulus and disc tissues
US7201774B2 (en) * 1999-10-08 2007-04-10 Ferree Bret A Artificial intervertebral disc replacements incorporating reinforced wall sections
US20030040796A1 (en) * 1999-10-08 2003-02-27 Ferree Bret A. Devices used to treat disc herniation and attachment mechanisms therefore
US7060100B2 (en) * 1999-10-08 2006-06-13 Ferree Bret A Artificial disc and joint replacements with modular cushioning components
US8679180B2 (en) * 1999-10-08 2014-03-25 Anova Corporation Devices used to treat disc herniation and attachment mechanisms therefore
US20040172019A1 (en) * 1999-10-08 2004-09-02 Ferree Bret A. Reinforcers for artificial disc replacement methods and apparatus
US6645247B2 (en) * 1999-10-08 2003-11-11 Bret A. Ferree Supplementing engineered annulus tissues with autograft of allograft tendons
US20030026788A1 (en) * 1999-10-08 2003-02-06 Ferree Bret A. Use of extracellular matrix tissue to preserve cultured cell phenotype
US6648919B2 (en) * 1999-10-14 2003-11-18 Bret A. Ferree Transplantation of engineered meniscus tissue to the intervertebral disc
US6520967B1 (en) * 1999-10-20 2003-02-18 Cauthen Research Group, Inc. Spinal implant insertion instrument for spinal interbody prostheses
US20030153976A1 (en) * 1999-10-20 2003-08-14 Cauthen Joseph C. Spinal disc annulus reconstruction method and spinal disc annulus stent
US6592625B2 (en) 1999-10-20 2003-07-15 Anulex Technologies, Inc. Spinal disc annulus reconstruction method and spinal disc annulus stent
US7052516B2 (en) 1999-10-20 2006-05-30 Anulex Technologies, Inc. Spinal disc annulus reconstruction method and deformable spinal disc annulus stent
US7935147B2 (en) 1999-10-20 2011-05-03 Anulex Technologies, Inc. Method and apparatus for enhanced delivery of treatment device to the intervertebral disc annulus
US8128698B2 (en) 1999-10-20 2012-03-06 Anulex Technologies, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
WO2001028464A1 (en) 1999-10-20 2001-04-26 Anulex Technologies, Inc. Spinal disc annulus reconstruction method and spinal disc annulus stent
EP1974698A3 (en) 1999-10-20 2009-01-28 Anulex Technologies, Inc. Spinal disc annulus stent
US7951201B2 (en) 1999-10-20 2011-05-31 Anulex Technologies, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
US8632590B2 (en) 1999-10-20 2014-01-21 Anulex Technologies, Inc. Apparatus and methods for the treatment of the intervertebral disc
US7615076B2 (en) 1999-10-20 2009-11-10 Anulex Technologies, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
US7004970B2 (en) 1999-10-20 2006-02-28 Anulex Technologies, Inc. Methods and devices for spinal disc annulus reconstruction and repair
ES2298675T3 (es) * 1999-10-22 2008-05-16 Archus Orthopedics Inc. Dispositivos de artroplastia facetaria.
US6811567B2 (en) * 1999-10-22 2004-11-02 Archus Orthopedics Inc. Facet arthroplasty devices and methods
US6974478B2 (en) * 1999-10-22 2005-12-13 Archus Orthopedics, Inc. Prostheses, systems and methods for replacement of natural facet joints with artificial facet joint surfaces
US7674293B2 (en) 2004-04-22 2010-03-09 Facet Solutions, Inc. Crossbar spinal prosthesis having a modular design and related implantation methods
US8187303B2 (en) * 2004-04-22 2012-05-29 Gmedelaware 2 Llc Anti-rotation fixation element for spinal prostheses
US7691145B2 (en) 1999-10-22 2010-04-06 Facet Solutions, Inc. Prostheses, systems and methods for replacement of natural facet joints with artificial facet joint surfaces
US20050027361A1 (en) * 1999-10-22 2005-02-03 Reiley Mark A. Facet arthroplasty devices and methods
JP4672947B2 (ja) * 1999-12-06 2011-04-20 ウォーソー・オーソペディック・インコーポレーテッド 椎間板の治療装置及び方法
WO2001049220A1 (en) 1999-12-30 2001-07-12 Osteotech, Inc. Intervertebral implants
US20030191474A1 (en) * 2000-02-16 2003-10-09 Cragg Andrew H. Apparatus for performing a discectomy through a trans-sacral axial bore within the vertebrae of the spine
US7744599B2 (en) * 2000-02-16 2010-06-29 Trans1 Inc. Articulating spinal implant
US6899716B2 (en) * 2000-02-16 2005-05-31 Trans1, Inc. Method and apparatus for spinal augmentation
US6740093B2 (en) * 2000-02-28 2004-05-25 Stephen Hochschuler Method and apparatus for treating a vertebral body
US6425923B1 (en) * 2000-03-07 2002-07-30 Zimmer, Inc. Contourable polymer filled implant
US6632246B1 (en) * 2000-03-14 2003-10-14 Chondrosite, Llc Cartilage repair plug
US6626945B2 (en) * 2000-03-14 2003-09-30 Chondrosite, Llc Cartilage repair plug
US6805695B2 (en) 2000-04-04 2004-10-19 Spinalabs, Llc Devices and methods for annular repair of intervertebral discs
US6402750B1 (en) * 2000-04-04 2002-06-11 Spinlabs, Llc Devices and methods for the treatment of spinal disorders
EP1272131B1 (en) * 2000-04-05 2006-03-01 Kyphon Inc. Devices for treating fractured and/or diseased bone
US6436141B2 (en) 2000-04-07 2002-08-20 Surgical Dynamics, Inc. Apparatus for fusing adjacent bone structures
US6723335B1 (en) 2000-04-07 2004-04-20 Jeffrey William Moehlenbruck Methods and compositions for treating intervertebral disc degeneration
US20030040800A1 (en) * 2000-04-26 2003-02-27 Li Lehmann K. Apparatus and method for replacing the nucleus pulposus of an intervertebral disc or for replacing an entire intervertebral disc
US6478800B1 (en) 2000-05-08 2002-11-12 Depuy Acromed, Inc. Medical installation tool
DE10024922C1 (de) * 2000-05-19 2002-01-10 Roland Minda Künstliche Bandscheibe
US20030229348A1 (en) * 2000-05-25 2003-12-11 Sevrain Lionel C. Auxiliary vertebrae connecting device
DE60117377T2 (de) * 2000-05-25 2006-10-12 Orthoplex Llc, Boston Verankerungssystem zum befestigen von gegenständen an knochen
US7008427B2 (en) * 2000-05-25 2006-03-07 Orthoplex, Llc Inter-vertebral disc prosthesis for rachis through anterior surgery thereof
JP2003534849A (ja) 2000-05-30 2003-11-25 リン,ポール・エス 頸椎間に置くインプラント
US6533817B1 (en) 2000-06-05 2003-03-18 Raymedica, Inc. Packaged, partially hydrated prosthetic disc nucleus
US6749614B2 (en) 2000-06-23 2004-06-15 Vertelink Corporation Formable orthopedic fixation system with cross linking
US6899713B2 (en) 2000-06-23 2005-05-31 Vertelink Corporation Formable orthopedic fixation system
US6821277B2 (en) * 2000-06-23 2004-11-23 University Of Southern California Patent And Copyright Administration Percutaneous vertebral fusion system
US6964667B2 (en) 2000-06-23 2005-11-15 Sdgi Holdings, Inc. Formed in place fixation system with thermal acceleration
US6875212B2 (en) 2000-06-23 2005-04-05 Vertelink Corporation Curable media for implantable medical device
ES2341641T3 (es) * 2000-07-21 2010-06-24 The Spineology Group, Llc Un dispositivo de bolsa de malla porosa expansible y su uso para cirugia osea.
US20080086133A1 (en) * 2003-05-16 2008-04-10 Spineology Expandable porous mesh bag device and methods of use for reduction, filling, fixation and supporting of bone
US7125380B2 (en) * 2000-08-08 2006-10-24 Warsaw Orthopedic, Inc. Clamping apparatus and methods
CA2429246C (en) * 2000-08-08 2011-06-07 Vincent Bryan Implantable joint prosthesis
CA2426453A1 (en) * 2000-08-08 2002-02-14 Sdgi Holdings, Inc. (D/B/A Medtronic Sofamor Danek, Inc.) Improved method and apparatus for stereotactic implantation
US7601174B2 (en) * 2000-08-08 2009-10-13 Warsaw Orthopedic, Inc. Wear-resistant endoprosthetic devices
AU2001285488A1 (en) * 2000-08-28 2002-03-13 Advanced Bio Surfaces, Inc Method for mammalian joint resurfacing
US7503936B2 (en) 2000-08-30 2009-03-17 Warsaw Orthopedic, Inc. Methods for forming and retaining intervertebral disc implants
US20020026244A1 (en) * 2000-08-30 2002-02-28 Trieu Hai H. Intervertebral disc nucleus implants and methods
US20050154463A1 (en) * 2000-08-30 2005-07-14 Trieu Hal H. Spinal nucleus replacement implants and methods
ES2252281T3 (es) * 2000-08-30 2006-05-16 Sdgi Holdings, Inc. Implantes de nucleo de disco intervertebral.
US7204851B2 (en) 2000-08-30 2007-04-17 Sdgi Holdings, Inc. Method and apparatus for delivering an intervertebral disc implant
US6620196B1 (en) 2000-08-30 2003-09-16 Sdgi Holdings, Inc. Intervertebral disc nucleus implants and methods
US6761738B1 (en) * 2000-09-19 2004-07-13 Sdgi Holdings, Inc. Reinforced molded implant formed of cortical bone
WO2002026170A2 (en) * 2000-09-26 2002-04-04 Neurortho Implants Design, Llc Inter-vertebral disc prosthesis for lumbar rachis through posterior surgery thereof
US20080177310A1 (en) * 2000-10-20 2008-07-24 Archus Orthopedics, Inc. Facet arthroplasty devices and methods
US6733531B1 (en) * 2000-10-20 2004-05-11 Sdgi Holdings, Inc. Anchoring devices and implants for intervertebral disc augmentation
US20030120274A1 (en) 2000-10-20 2003-06-26 Morris John W. Implant retaining device
US6582467B1 (en) * 2000-10-31 2003-06-24 Vertelink Corporation Expandable fusion cage
US6692528B2 (en) * 2000-11-09 2004-02-17 The Polymer Technology Group Incorporated Devices that change size/shape via osmotic pressure
US7776310B2 (en) 2000-11-16 2010-08-17 Microspherix Llc Flexible and/or elastic brachytherapy seed or strand
US20050080486A1 (en) * 2000-11-29 2005-04-14 Fallin T. Wade Facet joint replacement
US6579319B2 (en) 2000-11-29 2003-06-17 Medicinelodge, Inc. Facet joint replacement
US6565605B2 (en) 2000-12-13 2003-05-20 Medicinelodge, Inc. Multiple facet joint replacement
US6419703B1 (en) 2001-03-01 2002-07-16 T. Wade Fallin Prosthesis for the replacement of a posterior element of a vertebra
US6623509B2 (en) * 2000-12-14 2003-09-23 Core Medical, Inc. Apparatus and methods for sealing vascular punctures
US6890343B2 (en) 2000-12-14 2005-05-10 Ensure Medical, Inc. Plug with detachable guidewire element and methods for use
US6896692B2 (en) 2000-12-14 2005-05-24 Ensure Medical, Inc. Plug with collet and apparatus and method for delivering such plugs
US8083768B2 (en) 2000-12-14 2011-12-27 Ensure Medical, Inc. Vascular plug having composite construction
US6846319B2 (en) 2000-12-14 2005-01-25 Core Medical, Inc. Devices for sealing openings through tissue and apparatus and methods for delivering them
WO2002056802A1 (en) * 2000-12-15 2002-07-25 Spineology, Inc. Annulus-reinforcing band
DE60207902T2 (de) * 2001-01-30 2006-06-14 Nissan Chemical Ind Ltd Isocyanuratverbindung und Verfahren zu ihrer Herstellung
US6562045B2 (en) 2001-02-13 2003-05-13 Sdgi Holdings, Inc. Machining apparatus
US7371238B2 (en) * 2001-02-16 2008-05-13 Queen's University At Kingston Method and device for treating scoliosis
US7763769B2 (en) 2001-02-16 2010-07-27 Kci Licensing, Inc. Biocompatible wound dressing
US7700819B2 (en) 2001-02-16 2010-04-20 Kci Licensing, Inc. Biocompatible wound dressing
US7229441B2 (en) * 2001-02-28 2007-06-12 Warsaw Orthopedic, Inc. Flexible systems for spinal stabilization and fixation
US6652585B2 (en) * 2001-02-28 2003-11-25 Sdgi Holdings, Inc. Flexible spine stabilization system
US6827743B2 (en) * 2001-02-28 2004-12-07 Sdgi Holdings, Inc. Woven orthopedic implants
US7090698B2 (en) 2001-03-02 2006-08-15 Facet Solutions Method and apparatus for spine joint replacement
US6899734B2 (en) 2001-03-23 2005-05-31 Howmedica Osteonics Corp. Modular implant for fusing adjacent bone structure
US7344539B2 (en) * 2001-03-30 2008-03-18 Depuy Acromed, Inc. Intervertebral connection system
US20020147496A1 (en) 2001-04-06 2002-10-10 Integrated Vascular Systems, Inc. Apparatus for treating spinal discs
US20040083002A1 (en) * 2001-04-06 2004-04-29 Belef William Martin Methods for treating spinal discs
US6582433B2 (en) 2001-04-09 2003-06-24 St. Francis Medical Technologies, Inc. Spine fixation device and method
US20030078579A1 (en) * 2001-04-19 2003-04-24 Ferree Bret A. Annular repair devices and methods
US6632235B2 (en) 2001-04-19 2003-10-14 Synthes (U.S.A.) Inflatable device and method for reducing fractures in bone and in treating the spine
US6974480B2 (en) 2001-05-03 2005-12-13 Synthes (Usa) Intervertebral implant for transforaminal posterior lumbar interbody fusion procedure
US6719794B2 (en) * 2001-05-03 2004-04-13 Synthes (U.S.A.) Intervertebral implant for transforaminal posterior lumbar interbody fusion procedure
US20040220669A1 (en) * 2001-06-27 2004-11-04 Armin Studer Intervertebral disk prosthesis
US7156877B2 (en) * 2001-06-29 2007-01-02 The Regents Of The University Of California Biodegradable/bioactive nucleus pulposus implant and method for treating degenerated intervertebral discs
US20090234457A1 (en) * 2001-06-29 2009-09-17 The Regents Of The University Of California Systems, devices and methods for treatment of intervertebral disorders
US6926728B2 (en) * 2001-07-18 2005-08-09 St. Francis Medical Technologies, Inc. Curved dilator and method
EP1638484A4 (en) * 2001-07-25 2011-08-24 Kyphon Sarl DEFORMABLE TOOLS AND IMPLANTS
US6375682B1 (en) 2001-08-06 2002-04-23 Lewis W. Fleischmann Collapsible, rotatable and expandable spinal hydraulic prosthetic device
US6736815B2 (en) * 2001-09-06 2004-05-18 Core Medical, Inc. Apparatus and methods for treating spinal discs
US6783721B2 (en) * 2001-10-30 2004-08-31 Howmedica Osteonics Corp. Method of making an ion treated hydrogel
EP1448089A4 (en) * 2001-11-01 2008-06-04 Spine Wave Inc DEVICES AND METHODS FOR SPINACH RECOVERY
JP4125234B2 (ja) 2001-11-01 2008-07-30 スパイン・ウェイブ・インコーポレーテッド 椎間板間の終板の前処理のための装置及び方法
US7074291B2 (en) * 2001-11-02 2006-07-11 Worldwide Medical Technologies, L.L.C. Delivery system and method for interstitial radiation therapy using strands constructed with extruded strand housings
US7060020B2 (en) * 2001-11-02 2006-06-13 Ideamatrix, Inc. Delivery system and method for interstitial radiation therapy
US7285121B2 (en) 2001-11-05 2007-10-23 Warsaw Orthopedic, Inc. Devices and methods for the correction and treatment of spinal deformities
GB2382028B (en) * 2001-11-19 2006-11-01 Aberdeen Orthopaedic Developme Intervertebral disc prosthesis
US7025787B2 (en) * 2001-11-26 2006-04-11 Sdgi Holdings, Inc. Implantable joint prosthesis and associated instrumentation
US6855167B2 (en) 2001-12-05 2005-02-15 Osteotech, Inc. Spinal intervertebral implant, interconnections for such implant and processes for making
EP1465558B1 (en) * 2001-12-10 2009-07-01 Colbar Lifescience Ltd. Use of cross-linked collagen for intervertebral disc treatment
WO2003053278A2 (en) * 2001-12-19 2003-07-03 Advanced Bio Surfaces, Inc. Bone smoothing method and system
US7232802B2 (en) 2001-12-21 2007-06-19 Zimmer Orthobiologics, Inc. Compositions and methods for promoting myocardial and peripheral angiogenesis
US6736850B2 (en) * 2001-12-28 2004-05-18 Spinal Concepts, Inc. Vertebral pseudo arthrosis device and method
US20060129242A1 (en) * 2001-12-28 2006-06-15 Brian Bergeron Pseudo arthrosis device
JP4324478B2 (ja) * 2002-01-22 2009-09-02 アドバンスト バイオ サーフェイシズ,インコーポレイティド 間置関節形成システム
AU2003215099A1 (en) * 2002-02-07 2003-09-02 Ebi, L.P. Anterior spinal implant
US20030220692A1 (en) * 2002-02-09 2003-11-27 Shapiro Irving M. Preparations of nucleus pulposus cells and methods for their generation, identification, and use
US7223289B2 (en) * 2002-04-16 2007-05-29 Warsaw Orthopedic, Inc. Annulus repair systems and techniques
US7223227B2 (en) * 2002-05-13 2007-05-29 Pflueger D Russell Spinal disc therapy system
US20040049283A1 (en) * 2002-06-04 2004-03-11 Tushar Patel Medical implant and method of reducing back pain
US7622562B2 (en) 2002-06-26 2009-11-24 Zimmer Orthobiologics, Inc. Rapid isolation of osteoinductive protein mixtures from mammalian bone tissue
US6793678B2 (en) 2002-06-27 2004-09-21 Depuy Acromed, Inc. Prosthetic intervertebral motion disc having dampening
WO2004006811A2 (en) * 2002-07-11 2004-01-22 Advanced Bio Surfaces, Inc. Method and kit for interpositional arthroplasty
US20040022771A1 (en) * 2002-07-30 2004-02-05 Ferree Bret A. Transfer of cells, tissue, and other substances to bone
US7745532B2 (en) * 2002-08-02 2010-06-29 Cambridge Polymer Group, Inc. Systems and methods for controlling and forming polymer gels
US7485670B2 (en) * 2002-08-02 2009-02-03 Cambridge Polymer Group, Inc. Systems and methods for controlling and forming polymer gels
KR100984627B1 (ko) 2002-08-15 2010-09-30 신세스 게엠바하 추간 원판 임플란트
CA2495373C (en) 2002-08-15 2012-07-24 David Gerber Controlled artificial intervertebral disc implant
AU2003270524A1 (en) * 2002-09-10 2004-04-30 Bret A. Ferree Shock-absorbing joint and spine replacements
US20040054413A1 (en) * 2002-09-16 2004-03-18 Howmedica Osteonics Corp. Radiovisible hydrogel intervertebral disc nucleus
US20040054414A1 (en) * 2002-09-18 2004-03-18 Trieu Hai H. Collagen-based materials and methods for augmenting intervertebral discs
US7887593B2 (en) * 2002-09-18 2011-02-15 Warsaw Orthopedic, Inc. Method of implanting natural tissue within the vertebral disc nucleus space using a drawstring
US7309359B2 (en) * 2003-08-21 2007-12-18 Warsaw Orthopedic, Inc. Allogenic/xenogenic implants and methods for augmenting or repairing intervertebral discs
US7744651B2 (en) 2002-09-18 2010-06-29 Warsaw Orthopedic, Inc Compositions and methods for treating intervertebral discs with collagen-based materials
ES2343951T3 (es) * 2002-09-24 2010-08-13 Bogomir Gorensek Dispositivo estabilizador para disco intervertebral y metodos para ello.
US8679179B2 (en) * 2002-10-03 2014-03-25 Anova Corp. Annular repair devices and methods
US7320686B2 (en) * 2002-10-09 2008-01-22 Depuy Acromed, Inc. Device for distracting vertebrae and delivering a flowable material into a disc space
US7214243B2 (en) * 2002-10-21 2007-05-08 3Hbfm, Llc Intervertebral disk prosthesis
US20050090936A1 (en) * 2003-10-24 2005-04-28 Hitt Dale K. Two-wire control of sprinkler system
US7497859B2 (en) 2002-10-29 2009-03-03 Kyphon Sarl Tools for implanting an artificial vertebral disk
US7931674B2 (en) 2005-03-21 2011-04-26 Kyphon Sarl Interspinous process implant having deployable wing and method of implantation
US7909853B2 (en) 2004-09-23 2011-03-22 Kyphon Sarl Interspinous process implant including a binder and method of implantation
US20060271194A1 (en) * 2005-03-22 2006-11-30 St. Francis Medical Technologies, Inc. Interspinous process implant having deployable wing as an adjunct to spinal fusion and method of implantation
US6966929B2 (en) 2002-10-29 2005-11-22 St. Francis Medical Technologies, Inc. Artificial vertebral disk replacement implant with a spacer
US7083649B2 (en) * 2002-10-29 2006-08-01 St. Francis Medical Technologies, Inc. Artificial vertebral disk replacement implant with translating pivot point
US8070778B2 (en) 2003-05-22 2011-12-06 Kyphon Sarl Interspinous process implant with slide-in distraction piece and method of implantation
US7273496B2 (en) 2002-10-29 2007-09-25 St. Francis Medical Technologies, Inc. Artificial vertebral disk replacement implant with crossbar spacer and method
US7549999B2 (en) 2003-05-22 2009-06-23 Kyphon Sarl Interspinous process distraction implant and method of implantation
US8048117B2 (en) 2003-05-22 2011-11-01 Kyphon Sarl Interspinous process implant and method of implantation
US7833246B2 (en) 2002-10-29 2010-11-16 Kyphon SÀRL Interspinous process and sacrum implant and method
US7682392B2 (en) 2002-10-30 2010-03-23 Depuy Spine, Inc. Regenerative implants for stabilizing the spine and devices for attachment of said implants
US20040133278A1 (en) * 2002-10-31 2004-07-08 Marino James F. Spinal disc implant
WO2004041075A2 (en) * 2002-11-05 2004-05-21 Spineology, Inc. A semi-biological intervertebral disc replacement system
CN100394989C (zh) 2002-11-15 2008-06-18 华沙整形外科股份有限公司 包含微粒状基于胶原材料的组合物的制药应用和包含所述组合物的滑膜关节
US6733533B1 (en) * 2002-11-19 2004-05-11 Zimmer Technology, Inc. Artificial spinal disc
WO2004047689A1 (en) * 2002-11-21 2004-06-10 Sdgi Holdings, Inc. Systems and techniques for intravertebral spinal stablization with expandable devices
CN1713863A (zh) * 2002-11-21 2005-12-28 Sdgi控股股份有限公司 以可扩张的设备用于椎骨内脊椎稳定的系统和方法
US20040186471A1 (en) * 2002-12-07 2004-09-23 Sdgi Holdings, Inc. Method and apparatus for intervertebral disc expansion
US6974479B2 (en) * 2002-12-10 2005-12-13 Sdgi Holdings, Inc. System and method for blocking and/or retaining a prosthetic spinal implant
US20040210310A1 (en) * 2002-12-10 2004-10-21 Trieu Hai H. Implant system and method for intervertebral disc augmentation
TW554739U (en) * 2002-12-18 2003-09-21 Guan-Gu Lin Flexible non-airtight medical filling device
US7192447B2 (en) 2002-12-19 2007-03-20 Synthes (Usa) Intervertebral implant
FR2850282B1 (fr) * 2003-01-27 2007-04-06 Jerome Asius Implant injectable a base de ceramique pour le comblement de rides, depressions cutanees et cicatrices, et sa preparation
AU2004208821B2 (en) * 2003-01-31 2009-01-15 Zimmer Orthobiologics Inc. Hydrogel compositions comprising nucleus pulposus tissue
US7335203B2 (en) * 2003-02-12 2008-02-26 Kyphon Inc. System and method for immobilizing adjacent spinous processes
US7364589B2 (en) * 2003-02-12 2008-04-29 Warsaw Orthopedic, Inc. Mobile bearing articulating disc
AU2004212942A1 (en) 2003-02-14 2004-09-02 Depuy Spine, Inc. In-situ formed intervertebral fusion device
US7648509B2 (en) 2003-03-10 2010-01-19 Ilion Medical Llc Sacroiliac joint immobilization
US20080033446A1 (en) * 2003-03-11 2008-02-07 Kwan-Ku Lin Flexible and breathable filler for medical application
WO2004080357A1 (es) 2003-03-14 2004-09-23 Ferreyro Irigoyen Roque Humber Dispositivo hidraulico de inyección de cemento oseo en la vertebroplastiá percutánea
US8066713B2 (en) 2003-03-31 2011-11-29 Depuy Spine, Inc. Remotely-activated vertebroplasty injection device
WO2004089240A2 (en) 2003-04-04 2004-10-21 Theken Disc, Llc Artificial disc prosthesis
US6981989B1 (en) 2003-04-22 2006-01-03 X-Pantu-Flex Drd Limited Liability Company Rotatable and reversibly expandable spinal hydraulic prosthetic device
US7419505B2 (en) * 2003-04-22 2008-09-02 Fleischmann Lewis W Collapsible, rotatable, and tiltable hydraulic spinal disc prosthesis system with selectable modular components
US6969405B2 (en) * 2003-04-23 2005-11-29 Loubert Suddaby Inflatable intervertebral disc replacement prosthesis
US6997862B2 (en) * 2003-05-13 2006-02-14 Ideamatrix, Inc. Delivery system and method for interstitial radiation therapy using seed strands with custom end spacing
US20040230201A1 (en) * 2003-05-14 2004-11-18 Archus Orthopedics Inc. Prostheses, tools and methods for replacement of natural facet joints with artifical facet joint surfaces
US7608104B2 (en) 2003-05-14 2009-10-27 Archus Orthopedics, Inc. Prostheses, tools and methods for replacement of natural facet joints with artifical facet joint surfaces
US20040230304A1 (en) * 2003-05-14 2004-11-18 Archus Orthopedics Inc. Prostheses, tools and methods for replacement of natural facet joints with artifical facet joint surfaces
US20040249459A1 (en) * 2003-06-02 2004-12-09 Ferree Bret A. Nucleus replacements with asymmetrical stiffness
US8415407B2 (en) * 2004-03-21 2013-04-09 Depuy Spine, Inc. Methods, materials, and apparatus for treating bone and other tissue
US20070032567A1 (en) * 2003-06-17 2007-02-08 Disc-O-Tech Medical Bone Cement And Methods Of Use Thereof
DE602004031612D1 (de) 2003-06-20 2011-04-14 Intrinsic Therapeutics Inc Vorrichtung zur abgabe eines implantats durch einen ringförmigen defekt in einer bandscheibe
US20040260300A1 (en) * 2003-06-20 2004-12-23 Bogomir Gorensek Method of delivering an implant through an annular defect in an intervertebral disc
US20040267367A1 (en) 2003-06-30 2004-12-30 Depuy Acromed, Inc Intervertebral implant with conformable endplate
KR20050004526A (ko) * 2003-07-02 2005-01-12 김현집 디스크 치료용 보형물 및 그 보형물 시술방법
US7074238B2 (en) 2003-07-08 2006-07-11 Archus Orthopedics, Inc. Prostheses, tools and methods for replacement of natural facet joints with artificial facet joint surfaces
US20050015140A1 (en) * 2003-07-14 2005-01-20 Debeer Nicholas Encapsulation device and methods of use
US20050015150A1 (en) * 2003-07-17 2005-01-20 Lee Casey K. Intervertebral disk and nucleus prosthesis
US7794480B2 (en) * 2003-08-05 2010-09-14 Flexuspine, Inc. Artificial functional spinal unit system and method for use
US7753958B2 (en) 2003-08-05 2010-07-13 Gordon Charles R Expandable intervertebral implant
US7909869B2 (en) 2003-08-05 2011-03-22 Flexuspine, Inc. Artificial spinal unit assemblies
US7169405B2 (en) * 2003-08-06 2007-01-30 Warsaw Orthopedic, Inc. Methods and devices for the treatment of intervertebral discs
US9254137B2 (en) * 2003-08-29 2016-02-09 Lanterna Medical Technologies Ltd Facet implant
US20050055099A1 (en) * 2003-09-09 2005-03-10 Ku David N. Flexible spinal disc
WO2005030034A2 (en) 2003-09-26 2005-04-07 Depuy Spine, Inc. Device for delivering viscous material
US7632294B2 (en) * 2003-09-29 2009-12-15 Promethean Surgical Devices, Llc Devices and methods for spine repair
US7655010B2 (en) * 2003-09-30 2010-02-02 Depuy Spine, Inc. Vertebral fusion device and method for using same
US7361183B2 (en) * 2003-10-17 2008-04-22 Ensure Medical, Inc. Locator and delivery device and method of use
US8852229B2 (en) 2003-10-17 2014-10-07 Cordis Corporation Locator and closure device and method of use
US20050137604A1 (en) * 2003-10-23 2005-06-23 Assell Robert L. Method and apparatus for introducing material along an access path to a treatment site
US7651682B2 (en) * 2003-10-29 2010-01-26 Gentis, Inc. Polymerizable emulsions for tissue engineering
US7320707B2 (en) 2003-11-05 2008-01-22 St. Francis Medical Technologies, Inc. Method of laterally inserting an artificial vertebral disk replacement implant with crossbar spacer
US7837732B2 (en) 2003-11-20 2010-11-23 Warsaw Orthopedic, Inc. Intervertebral body fusion cage with keels and implantation methods
US7691146B2 (en) 2003-11-21 2010-04-06 Kyphon Sarl Method of laterally inserting an artificial vertebral disk replacement implant with curved spacer
US20050283237A1 (en) * 2003-11-24 2005-12-22 St. Francis Medical Technologies, Inc. Artificial spinal disk replacement device with staggered vertebral body attachments
US20050154462A1 (en) * 2003-12-02 2005-07-14 St. Francis Medical Technologies, Inc. Laterally insertable artificial vertebral disk replacement implant with translating pivot point
US20050209603A1 (en) * 2003-12-02 2005-09-22 St. Francis Medical Technologies, Inc. Method for remediation of intervertebral disks
US7217291B2 (en) 2003-12-08 2007-05-15 St. Francis Medical Technologies, Inc. System and method for replacing degenerated spinal disks
US7588590B2 (en) 2003-12-10 2009-09-15 Facet Solutions, Inc Spinal facet implant with spherical implant apposition surface and bone bed and methods of use
US20050143826A1 (en) * 2003-12-11 2005-06-30 St. Francis Medical Technologies, Inc. Disk repair structures with anchors
US20050131406A1 (en) 2003-12-15 2005-06-16 Archus Orthopedics, Inc. Polyaxial adjustment of facet joint prostheses
US7255713B2 (en) * 2003-12-18 2007-08-14 Malek Michel H Systems and methods for agent delivery
FR2863868B1 (fr) 2003-12-22 2006-09-08 Fournitures Hospitalieres Ind Prothese de disque intervertebral
JP4440939B2 (ja) 2004-01-08 2010-03-24 スパイン・ウェイブ・インコーポレーテッド 伸延した組織部位に流動性材料を注入する装置及び方法
US20050159746A1 (en) * 2004-01-21 2005-07-21 Dieter Grob Cervical facet resurfacing implant
US20050177104A1 (en) * 2004-01-22 2005-08-11 Rochester Medical Corporation Cuff resistant foley catheter
NZ579516A (en) 2004-01-27 2011-01-28 Osteotech Inc Stabilized bone graft
US20100063174A1 (en) * 2004-02-04 2010-03-11 Ruberti Jeffrey W Systems and methods for controlling and forming polymer gels
US7846183B2 (en) * 2004-02-06 2010-12-07 Spinal Elements, Inc. Vertebral facet joint prosthesis and method of fixation
US8333789B2 (en) 2007-01-10 2012-12-18 Gmedelaware 2 Llc Facet joint replacement
US8562649B2 (en) 2004-02-17 2013-10-22 Gmedelaware 2 Llc System and method for multiple level facet joint arthroplasty and fusion
US7993373B2 (en) 2005-02-22 2011-08-09 Hoy Robert W Polyaxial orthopedic fastening apparatus
US7806933B2 (en) * 2004-03-15 2010-10-05 Warsaw Orthopedic, Inc. System and method for stabilizing a prosthetic device
US8029511B2 (en) * 2004-03-22 2011-10-04 Disc Dynamics, Inc. Multi-stage biomaterial injection system for spinal implants
US20060135959A1 (en) * 2004-03-22 2006-06-22 Disc Dynamics, Inc. Nuclectomy method and apparatus
AU2005225205B9 (en) * 2004-03-26 2009-11-19 Nuvasive, Inc. Prosthetic spinal disc
US7452351B2 (en) * 2004-04-16 2008-11-18 Kyphon Sarl Spinal diagnostic methods and apparatus
US7824390B2 (en) * 2004-04-16 2010-11-02 Kyphon SÀRL Spinal diagnostic methods and apparatus
US7406775B2 (en) 2004-04-22 2008-08-05 Archus Orthopedics, Inc. Implantable orthopedic device component selection instrument and methods
WO2006055186A2 (en) 2004-10-25 2006-05-26 Archus Orthopedics, Inc. Spinal prosthesis having a modular design
US7051451B2 (en) 2004-04-22 2006-05-30 Archus Orthopedics, Inc. Facet joint prosthesis measurement and implant tools
US20080082171A1 (en) * 2004-04-22 2008-04-03 Kuiper Mark K Crossbar spinal prosthesis having a modular design and systems for treating spinal pathologies
US7282165B2 (en) * 2004-04-27 2007-10-16 Howmedica Osteonics Corp. Wear resistant hydrogel for bearing applications
US7524324B2 (en) 2004-04-28 2009-04-28 Kyphon Sarl System and method for an interspinous process implant as a supplement to a spine stabilization implant
US20070093833A1 (en) * 2004-05-03 2007-04-26 Kuiper Mark K Crossbar spinal prosthesis having a modular design and related implantation methods
US20080269900A1 (en) * 2004-05-20 2008-10-30 Christopher Reah Surgical Implants
US8764801B2 (en) 2005-03-28 2014-07-01 Gmedelaware 2 Llc Facet joint implant crosslinking apparatus and method
US7588578B2 (en) 2004-06-02 2009-09-15 Facet Solutions, Inc Surgical measurement systems and methods
US20060036258A1 (en) * 2004-06-08 2006-02-16 St. Francis Medical Technologies, Inc. Sizing distractor and method for implanting an interspinous implant between adjacent spinous processes
US20060095138A1 (en) 2004-06-09 2006-05-04 Csaba Truckai Composites and methods for treating bone
US9504583B2 (en) 2004-06-10 2016-11-29 Spinal Elements, Inc. Implant and method for facet immobilization
JP2008504895A (ja) * 2004-06-29 2008-02-21 スパイン・ウェイブ・インコーポレーテッド 椎間板の欠陥及び損傷を治療する方法
US7776073B2 (en) * 2004-06-30 2010-08-17 Depuy Spine, Inc. In-situ formed posterolateral fusion system
US7172628B2 (en) * 2004-07-27 2007-02-06 Lonnie Jay Lamprich Spinal disc prosthesis and methods
US7862617B2 (en) * 2004-07-27 2011-01-04 Lamprich Medical, Llc Spinal disc prosthesis apparatus and placement method
EP1786343B1 (en) 2004-07-30 2012-05-02 Depuy Spine, Inc. Apparatus for treating bone and other tissue
CA2576636A1 (en) 2004-08-18 2006-03-02 Archus Orthopedics, Inc. Adjacent level facet arthroplasty devices, spine stabilization systems, and methods
US20060041311A1 (en) * 2004-08-18 2006-02-23 Mcleer Thomas J Devices and methods for treating facet joints
US20060040878A1 (en) * 2004-08-20 2006-02-23 Loubert Suddaby Bacterial antigen induced bone morphogenesis
US20060052870A1 (en) * 2004-09-09 2006-03-09 Ferree Bret A Methods and apparatus to prevent movement through artificial disc replacements
US20060058892A1 (en) * 2004-09-16 2006-03-16 Lesh Michael D Valved tissue augmentation implant
US20060058891A1 (en) * 2004-09-16 2006-03-16 Lesh Michael D Transformable tissue bulking device
US20060058881A1 (en) * 2004-09-16 2006-03-16 Trieu Hai H Intervertebral disc nucleus implants and methods
US7303074B2 (en) * 2004-09-22 2007-12-04 Dombrowski Trudy M Foldable organizer device
US7780731B2 (en) * 2004-11-26 2010-08-24 Spine Solutions, Inc. Intervertebral implant
US7763024B2 (en) * 2004-09-23 2010-07-27 Spine Solutions, Inc. Adjustable cutting of cutout in vertebral bone
US8012209B2 (en) 2004-09-23 2011-09-06 Kyphon Sarl Interspinous process implant including a binder, binder aligner and method of implantation
US20060069438A1 (en) * 2004-09-29 2006-03-30 Zucherman James F Multi-piece artificial spinal disk replacement device with multi-segmented support plates
US7481840B2 (en) 2004-09-29 2009-01-27 Kyphon Sarl Multi-piece artificial spinal disk replacement device with selectably positioning articulating element
US7575600B2 (en) 2004-09-29 2009-08-18 Kyphon Sarl Artificial vertebral disk replacement implant with translating articulation contact surface and method
US20060079895A1 (en) * 2004-09-30 2006-04-13 Mcleer Thomas J Methods and devices for improved bonding of devices to bone
US20060085075A1 (en) * 2004-10-04 2006-04-20 Archus Orthopedics, Inc. Polymeric joint complex and methods of use
US7235592B2 (en) 2004-10-12 2007-06-26 Zimmer Gmbh PVA hydrogel
US8721722B2 (en) 2004-10-18 2014-05-13 Ebi, Llc Intervertebral implant and associated method
US20060085073A1 (en) * 2004-10-18 2006-04-20 Kamshad Raiszadeh Medical device systems for the spine
US20060085077A1 (en) * 2004-10-18 2006-04-20 Ebi, L.P. Intervertebral implant and associated method
US20060089719A1 (en) * 2004-10-21 2006-04-27 Trieu Hai H In situ formation of intervertebral disc implants
EP1812090A1 (en) * 2004-10-28 2007-08-01 Microchips, Inc. Orthopedic and dental implant devices providing controlled drug delivery
US7678116B2 (en) * 2004-12-06 2010-03-16 Dfine, Inc. Bone treatment systems and methods
US7559932B2 (en) * 2004-12-06 2009-07-14 Dfine, Inc. Bone treatment systems and methods
US8070753B2 (en) 2004-12-06 2011-12-06 Dfine, Inc. Bone treatment systems and methods
US7722620B2 (en) 2004-12-06 2010-05-25 Dfine, Inc. Bone treatment systems and methods
US7717918B2 (en) 2004-12-06 2010-05-18 Dfine, Inc. Bone treatment systems and methods
EP1827527B1 (en) * 2004-12-06 2016-08-24 Cook Incorporated Inflatable occlusion devices, methods, and systems
US20060122614A1 (en) * 2004-12-06 2006-06-08 Csaba Truckai Bone treatment systems and methods
US8100944B2 (en) 2004-12-13 2012-01-24 Kyphon Sarl Inter-cervical facet implant and method for preserving the tissues surrounding the facet joint
US7591851B2 (en) 2004-12-13 2009-09-22 Kyphon Sarl Inter-cervical facet implant and method
US8128660B2 (en) * 2004-12-13 2012-03-06 Kyphon Sarl Inter-cervical facet joint implant with locking screw system
US8118838B2 (en) * 2004-12-13 2012-02-21 Kyphon Sarl Inter-cervical facet implant with multiple direction articulation joint and method for implanting
US20070016218A1 (en) * 2005-05-10 2007-01-18 Winslow Charles J Inter-cervical facet implant with implantation tool
US20060247633A1 (en) * 2004-12-13 2006-11-02 St. Francis Medical Technologies, Inc. Inter-cervical facet implant with surface enhancements
US8029540B2 (en) * 2005-05-10 2011-10-04 Kyphon Sarl Inter-cervical facet implant with implantation tool
US8066749B2 (en) * 2004-12-13 2011-11-29 Warsaw Orthopedic, Inc. Implant for stabilizing a bone graft during spinal fusion
US20090264939A9 (en) * 2004-12-16 2009-10-22 Martz Erik O Instrument set and method for performing spinal nuclectomy
US20060282169A1 (en) * 2004-12-17 2006-12-14 Felt Jeffrey C System and method for upper extremity joint arthroplasty
JP4601051B2 (ja) * 2004-12-20 2010-12-22 株式会社ユニバーサルエンターテインメント ゲーム用チップ
AU2006203906A1 (en) * 2005-01-08 2006-07-13 Alphaspine, Inc. Modular disc device
EP1841387B1 (en) 2005-01-19 2011-12-21 Nexgen Spine, Inc. Elastomeric intervertebral disc prosthesis
AU2006206559A1 (en) * 2005-01-19 2006-07-27 Nexgen Spine, Inc. Fixation of elastomer to rigid structures
US20060276800A1 (en) * 2005-01-27 2006-12-07 Nexgen Spine, Inc. Intervertebral disc replacement and surgical instruments therefor
US8911498B2 (en) * 2005-02-10 2014-12-16 DePuy Synthes Products, LLC Intervertebral prosthetic disc
US7690381B2 (en) * 2005-02-10 2010-04-06 Depuy Spine, Inc. Intervertebral prosthetic disc and method for installing using a guidewire
AU2006216655B2 (en) 2005-02-23 2012-05-31 Zimmer Technology, Inc. Blend hydrogels and methods of making
US7267690B2 (en) * 2005-03-09 2007-09-11 Vertebral Technologies, Inc. Interlocked modular disc nucleus prosthesis
US7722647B1 (en) 2005-03-14 2010-05-25 Facet Solutions, Inc. Apparatus and method for posterior vertebral stabilization
AU2006227019A1 (en) * 2005-03-22 2006-09-28 Fsi Acquisition Sub, Llc Minimally invasive spine restoration systems, devices, methods and kits
US8496686B2 (en) 2005-03-22 2013-07-30 Gmedelaware 2 Llc Minimally invasive spine restoration systems, devices, methods and kits
US20060276801A1 (en) * 2005-04-04 2006-12-07 Yerby Scott A Inter-cervical facet implant distraction tool
US8864730B2 (en) 2005-04-12 2014-10-21 Rochester Medical Corporation Silicone rubber male external catheter with absorbent and adhesive
EP1868539A2 (en) * 2005-04-15 2007-12-26 Musculoskeletal Transplant Foundation Vertebral disc repair
US20060241766A1 (en) * 2005-04-20 2006-10-26 Sdgi Holdings, Inc. Method and apparatus for preventing articulation in an artificial joint
US7674296B2 (en) * 2005-04-21 2010-03-09 Globus Medical, Inc. Expandable vertebral prosthesis
US20060247780A1 (en) * 2005-04-27 2006-11-02 Bert Jeffrey K Expandable artificial disc and associated methods and instrumentation
US20060253199A1 (en) * 2005-05-03 2006-11-09 Disc Dynamics, Inc. Lordosis creating nucleus replacement method and apparatus
US20060253198A1 (en) * 2005-05-03 2006-11-09 Disc Dynamics, Inc. Multi-lumen mold for intervertebral prosthesis and method of using same
US8088144B2 (en) 2005-05-04 2012-01-03 Ensure Medical, Inc. Locator and closure device and method of use
US8926654B2 (en) 2005-05-04 2015-01-06 Cordis Corporation Locator and closure device and method of use
US20070050034A1 (en) * 2005-05-24 2007-03-01 Schwardt Jeffrey D Low-compliance expandable medical device
US20070042326A1 (en) * 2005-06-01 2007-02-22 Osseous Technologies Of America Collagen antral membrane expander
WO2006130796A2 (en) 2005-06-02 2006-12-07 Zimmer Spine, Inc. Interbody fusion ring and method of using the same
US20090105826A1 (en) * 2005-06-03 2009-04-23 Mcleod Alan Surgical Implants
GB0514891D0 (en) * 2005-07-20 2005-08-24 Pearsalls Ltd Improvements in and relating to implants
US7628800B2 (en) 2005-06-03 2009-12-08 Warsaw Orthopedic, Inc. Formed in place corpectomy device
US7988735B2 (en) * 2005-06-15 2011-08-02 Matthew Yurek Mechanical apparatus and method for delivering materials into the inter-vertebral body space for nucleus replacement
US7601172B2 (en) * 2005-06-15 2009-10-13 Ouroboros Medical, Inc. Mechanical apparatus and method for artificial disc replacement
WO2007001624A2 (en) * 2005-06-28 2007-01-04 Microchips, Inc. Medical and dental implant devices for controlled drug delivery
US8187159B2 (en) 2005-07-22 2012-05-29 Biocompatibles, UK Therapeutic member including a rail used in brachytherapy and other radiation therapy
US7736293B2 (en) 2005-07-22 2010-06-15 Biocompatibles Uk Limited Implants for use in brachytherapy and other radiation therapy that resist migration and rotation
US9381024B2 (en) 2005-07-31 2016-07-05 DePuy Synthes Products, Inc. Marked tools
US9918767B2 (en) 2005-08-01 2018-03-20 DePuy Synthes Products, Inc. Temperature control system
KR20080042861A (ko) * 2005-08-09 2008-05-15 트랜스1 인코포레이티드 축 방향 척추 시술을 위한 교체 시스템
WO2008131498A1 (en) 2007-05-01 2008-11-06 Columna Pty Ltd Systems methods and apparatuses for formation and insertion of tissue prostheses
WO2007022194A2 (en) 2005-08-16 2007-02-22 Benvenue Medical, Inc. Spinal tissue distraction devices
US8366773B2 (en) 2005-08-16 2013-02-05 Benvenue Medical, Inc. Apparatus and method for treating bone
US8777479B2 (en) 2008-10-13 2014-07-15 Dfine, Inc. System for use in bone cement preparation and delivery
US9066769B2 (en) 2005-08-22 2015-06-30 Dfine, Inc. Bone treatment systems and methods
US8540723B2 (en) 2009-04-14 2013-09-24 Dfine, Inc. Medical system and method of use
US20070162043A1 (en) * 2005-09-01 2007-07-12 Csaba Truckai Methods for sensing retrograde flows of bone fill material
US8603098B2 (en) * 2005-09-12 2013-12-10 K2M, Inc. Posterior modular disc replacement system
US20070073397A1 (en) * 2005-09-15 2007-03-29 Mckinley Laurence M Disc nucleus prosthesis and its method of insertion and revision
US20070067036A1 (en) * 2005-09-20 2007-03-22 Zimmer Spine, Inc. Hydrogel total disc prosthesis
US20080287959A1 (en) * 2005-09-26 2008-11-20 Archus Orthopedics, Inc. Measurement and trialing system and methods for orthopedic device component selection
US8236058B2 (en) 2005-09-27 2012-08-07 Fabian Henry F Spine surgery method and implant
US9271843B2 (en) 2005-09-27 2016-03-01 Henry F. Fabian Spine surgery method and implant
CA2627345A1 (en) 2005-10-24 2007-05-03 Nexgen Spine, Inc. Intervertebral disc replacement and associated instrumentation
EP1948096A2 (en) * 2005-10-26 2008-07-30 BioCure, Inc. Hydrogel spinal disc implants with swellable articles
WO2007062080A2 (en) * 2005-11-21 2007-05-31 Philipp Lang Intervetebral devices and methods
AU2006318531A1 (en) * 2005-11-22 2007-05-31 Bonwrx Method and composition for repair and reconstruction of intervertebral discs and other reconstructive surgery
US8360629B2 (en) 2005-11-22 2013-01-29 Depuy Spine, Inc. Mixing apparatus having central and planetary mixing elements
US8262730B2 (en) * 2005-12-07 2012-09-11 Zimmer, Inc. Methods of bonding or modifying hydrogels using irradiation
WO2007126428A2 (en) 2005-12-20 2007-11-08 Archus Orthopedics, Inc. Arthroplasty revision system and method
EP1801135B1 (en) 2005-12-22 2010-09-29 Zimmer Inc. Perfluorocyclobutane crosslinked hydrogels
US8506633B2 (en) * 2005-12-27 2013-08-13 Warsaw Orthopedic, Inc. Rehydration and restoration of intervertebral discs with polyelectrolytes
US8801790B2 (en) * 2005-12-27 2014-08-12 Warsaw Orthopedic, Inc. Intervertebral disc augmentation and rehydration with superabsorbent polymers
US20070173822A1 (en) * 2006-01-13 2007-07-26 Sdgi Holdings, Inc. Use of a posterior dynamic stabilization system with an intradiscal device
US7662183B2 (en) * 2006-01-24 2010-02-16 Timothy Haines Dynamic spinal implants incorporating cartilage bearing graft material
WO2007089739A2 (en) 2006-01-27 2007-08-09 Stryker Corporation Low pressure delivery system and method for delivering a solid and liquid mixture into a target site for medical treatment
US20070184087A1 (en) * 2006-02-06 2007-08-09 Bioform Medical, Inc. Polysaccharide compositions for use in tissue augmentation
US8377072B2 (en) 2006-02-06 2013-02-19 Depuy Spine, Inc. Medical device installation tool
US7520888B2 (en) * 2006-02-14 2009-04-21 Warsaw Orthopedic, Inc. Treatment of the vertebral column
US7918889B2 (en) * 2006-02-27 2011-04-05 Warsaw Orthopedic, Inc. Expandable spinal prosthetic devices and associated methods
US8118869B2 (en) 2006-03-08 2012-02-21 Flexuspine, Inc. Dynamic interbody device
WO2007106573A2 (en) * 2006-03-15 2007-09-20 Archus Orthopedics, Inc. Facet and disc arthroplasty systems and methods
US8110242B2 (en) 2006-03-24 2012-02-07 Zimmer, Inc. Methods of preparing hydrogel coatings
US8137404B2 (en) * 2006-03-28 2012-03-20 Depuy Spine, Inc. Artificial disc replacement using posterior approach
US20070233244A1 (en) * 2006-03-28 2007-10-04 Depuy Spine, Inc. Artificial Disc Replacement Using Posterior Approach
US8282641B2 (en) 2006-03-28 2012-10-09 Depuy Spine, Inc. Methods and instrumentation for disc replacement
US20070233245A1 (en) * 2006-03-31 2007-10-04 Sdgi Holdings, Inc. Methods and instruments for delivering intervertebral devices
JP5326566B2 (ja) * 2006-03-31 2013-10-30 日本ゼオン株式会社 リチウムイオン二次電池
ATE538740T1 (de) 2006-04-20 2012-01-15 Depuy Spine Inc Instrumentensatz zur abgabe eines viskosen knochenfüller-materials
US7771414B2 (en) * 2006-04-24 2010-08-10 Warsaw Orthopedic, Inc. Controlled release devices for therapeutic treatments of spinal discs
US8642060B2 (en) * 2006-04-24 2014-02-04 Warsaw Orthopedic, Inc. Controlled release systems and methods for osteal growth
US7879027B2 (en) * 2006-04-24 2011-02-01 Warsaw Orthopedic, Inc. Controlled release devices for fusion of osteal structures
US8642059B2 (en) * 2006-04-24 2014-02-04 Warsaw Orthopedic, Inc. Controlled release systems and methods for intervertebral discs
US20070255286A1 (en) * 2006-04-27 2007-11-01 Sdgi Holdings, Inc. Devices, apparatus, and methods for improved disc augmentation
US8133279B2 (en) * 2006-04-27 2012-03-13 Warsaw Orthopedic, Inc. Methods for treating an annulus defect of an intervertebral disc
US20070255406A1 (en) * 2006-04-27 2007-11-01 Sdgi Holdings, Inc. Devices, apparatus, and methods for bilateral approach to disc augmentation
US7988611B2 (en) 2006-05-09 2011-08-02 Biocompatibles Uk Limited After-loader for positioning implants for needle delivery in brachytherapy and other radiation therapy
US20080071379A1 (en) * 2006-05-10 2008-03-20 Mark Rydell Intervertebral disc replacement
US8834496B2 (en) 2006-06-13 2014-09-16 Bret A. Ferree Soft tissue repair methods and apparatus
US8821549B2 (en) 2006-06-13 2014-09-02 Anova Corporation Methods and apparatus for anulus repair
US8764835B2 (en) 2006-06-13 2014-07-01 Bret A. Ferree Intervertebral disc treatment methods and apparatus
US9232938B2 (en) 2006-06-13 2016-01-12 Anova Corp. Method and apparatus for closing fissures in the annulus fibrosus
US8118779B2 (en) 2006-06-30 2012-02-21 Warsaw Orthopedic, Inc. Collagen delivery device
US20080004703A1 (en) * 2006-06-30 2008-01-03 Warsaw Orthopedic, Inc. Method of treating a patient using a collagen material
US20080004431A1 (en) * 2006-06-30 2008-01-03 Warsaw Orthopedic Inc Method of manufacturing an injectable collagen material
US8399619B2 (en) 2006-06-30 2013-03-19 Warsaw Orthopedic, Inc. Injectable collagen material
US7780676B2 (en) 2006-07-11 2010-08-24 Ebi, Llc Intervertebral implantation apparatus
WO2008013763A2 (en) * 2006-07-25 2008-01-31 Musculoskeletal Transplant Foundation Packed demineralized cancellous tissue forms for disc nucleus augmentation, restoration, or replacement and methods of implantation
US20080026032A1 (en) * 2006-07-27 2008-01-31 Zubery Yuval Composite implants for promoting bone regeneration and augmentation and methods for their preparation and use
US8034110B2 (en) 2006-07-31 2011-10-11 Depuy Spine, Inc. Spinal fusion implant
US7758649B2 (en) * 2006-08-04 2010-07-20 Integrity Intellect Inc. Reversibly deformable implant
US8702755B2 (en) 2006-08-11 2014-04-22 Gmedelaware 2 Llc Angled washer polyaxial connection for dynamic spine prosthesis
US20080097229A1 (en) * 2006-08-29 2008-04-24 Josee Roy Hygroscopic treatment for degenerating discs
US7878964B1 (en) 2006-09-07 2011-02-01 Biocompatibles Uk Limited Echogenic spacers and strands
US7874976B1 (en) 2006-09-07 2011-01-25 Biocompatibles Uk Limited Echogenic strands and spacers therein
US8357168B2 (en) * 2006-09-08 2013-01-22 Spine Wave, Inc. Modular injection needle and seal assembly
US8506636B2 (en) 2006-09-08 2013-08-13 Theken Spine, Llc Offset radius lordosis
EP2068898A4 (en) 2006-09-14 2011-07-20 Depuy Spine Inc BONE CEMENT AND APPLICATION METHOD THEREFOR
WO2008033501A2 (en) * 2006-09-14 2008-03-20 Spineology, Inc. Absorbent fabric implant
US8074591B2 (en) * 2006-09-25 2011-12-13 Nuvasive, Inc. Embroidery using soluble thread
ES2542691T3 (es) * 2006-09-26 2015-08-10 Nexgen Spine, Inc. Placa terminal de prótesis intervertebral que presenta doble cúpula
US20100179659A1 (en) * 2006-09-27 2010-07-15 Wan-Ju Li Cell-nanofiber composite and cell-nanofiber-hydrogel composite amalgam based engineered intervertebral disc
US8066750B2 (en) 2006-10-06 2011-11-29 Warsaw Orthopedic, Inc Port structures for non-rigid bone plates
ES2587573T3 (es) 2006-10-19 2016-10-25 Depuy Spine, Inc. Sistema de liberación de fluidos y método relacionado
US20080177311A1 (en) * 2006-10-30 2008-07-24 St. Francis Medical Technologies, Inc. Facet joint implant sizing tool
US20080108990A1 (en) * 2006-11-02 2008-05-08 St. Francis Medical Technologies, Inc. Interspinous process implant having a fixed wing and a deployable wing and method of implantation
US9737414B2 (en) 2006-11-21 2017-08-22 Vertebral Technologies, Inc. Methods and apparatus for minimally invasive modular interbody fusion devices
WO2008070863A2 (en) 2006-12-07 2008-06-12 Interventional Spine, Inc. Intervertebral implant
US8696679B2 (en) * 2006-12-08 2014-04-15 Dfine, Inc. Bone treatment systems and methods
US8715352B2 (en) 2006-12-14 2014-05-06 Depuy Spine, Inc. Buckling disc replacement
US7905922B2 (en) 2006-12-20 2011-03-15 Zimmer Spine, Inc. Surgical implant suitable for replacement of an intervertebral disc
US20080177389A1 (en) * 2006-12-21 2008-07-24 Rob Gene Parrish Intervertebral disc spacer
US8758407B2 (en) * 2006-12-21 2014-06-24 Warsaw Orthopedic, Inc. Methods for positioning a load-bearing orthopedic implant device in vivo
US7771476B2 (en) 2006-12-21 2010-08-10 Warsaw Orthopedic Inc. Curable orthopedic implant devices configured to harden after placement in vivo by application of a cure-initiating energy before insertion
US8663328B2 (en) * 2006-12-21 2014-03-04 Warsaw Orthopedic, Inc. Methods for positioning a load-bearing component of an orthopedic implant device by inserting a malleable device that hardens in vivo
US8480718B2 (en) 2006-12-21 2013-07-09 Warsaw Orthopedic, Inc. Curable orthopedic implant devices configured to be hardened after placement in vivo
US7972382B2 (en) * 2006-12-26 2011-07-05 Warsaw Orthopedic, Inc. Minimally invasive spinal distraction devices and methods
US20080161929A1 (en) 2006-12-29 2008-07-03 Mccormack Bruce Cervical distraction device
US20080167655A1 (en) * 2007-01-05 2008-07-10 Jeffrey Chun Wang Interspinous implant, tools and methods of implanting
US8974496B2 (en) 2007-08-30 2015-03-10 Jeffrey Chun Wang Interspinous implant, tools and methods of implanting
EP2114273B1 (en) 2007-01-10 2013-11-06 Facet Solutions, Inc. Taper-locking fixation system
US7959677B2 (en) * 2007-01-19 2011-06-14 Flexuspine, Inc. Artificial functional spinal unit system and method for use
US7942104B2 (en) * 2007-01-22 2011-05-17 Nuvasive, Inc. 3-dimensional embroidery structures via tension shaping
US7946236B2 (en) * 2007-01-31 2011-05-24 Nuvasive, Inc. Using zigzags to create three-dimensional embroidered structures
WO2008098125A2 (en) * 2007-02-08 2008-08-14 Nuvasive, Inc. Medical implants with pre-settled cores and related methods
CA2677903A1 (en) 2007-02-12 2008-08-21 Osteotech, Inc. Joint revision implant
WO2008103832A2 (en) 2007-02-21 2008-08-28 Benvenue Medical, Inc. Devices for treating the spine
EP2124777A4 (en) 2007-02-21 2013-06-05 Benvenue Medical Inc DEVICES FOR SPINE COLUMN TREATMENT
EP2813190B1 (en) 2007-02-22 2017-04-26 Spinal Elements, Inc. Vertebral facet joint drill
US8992533B2 (en) 2007-02-22 2015-03-31 Spinal Elements, Inc. Vertebral facet joint drill and method of use
ES2438999T3 (es) * 2007-04-03 2014-01-21 Dfine, Inc. Sistemas de tratamiento óseo
US20080269897A1 (en) * 2007-04-26 2008-10-30 Abhijeet Joshi Implantable device and methods for repairing articulating joints for using the same
US20080268056A1 (en) * 2007-04-26 2008-10-30 Abhijeet Joshi Injectable copolymer hydrogel useful for repairing vertebral compression fractures
WO2008137428A2 (en) * 2007-04-30 2008-11-13 Dfine, Inc. Bone treatment systems and methods
WO2008139456A2 (en) * 2007-05-10 2008-11-20 Disc-O-Tech Medical Technologies, Ltd Expandable intramedullary nail for small bone fixation
US20080288074A1 (en) * 2007-05-15 2008-11-20 O'neil Michael J Internally reinforced elastomeric intervertebral disc implants
US7942930B2 (en) * 2007-06-15 2011-05-17 Q-Med Ab Biocompatible implant system and method
US8900307B2 (en) 2007-06-26 2014-12-02 DePuy Synthes Products, LLC Highly lordosed fusion cage
AU2008275679B2 (en) 2007-07-12 2014-10-09 Discgenics, Inc. Human disc tissue
US20090024174A1 (en) 2007-07-17 2009-01-22 Stark John G Bone screws and particular applications to sacroiliac joint fusion
US9597118B2 (en) 2007-07-20 2017-03-21 Dfine, Inc. Bone anchor apparatus and method
CA2694558C (en) * 2007-07-25 2014-06-03 Depuy Spine, Inc. Expandable bone filler materials and methods of using same
US7731988B2 (en) 2007-08-03 2010-06-08 Zimmer, Inc. Multi-polymer hydrogels
US8282681B2 (en) * 2007-08-13 2012-10-09 Nuvasive, Inc. Bioresorbable spinal implant and related methods
US8062739B2 (en) 2007-08-31 2011-11-22 Zimmer, Inc. Hydrogels with gradient
US20110196492A1 (en) 2007-09-07 2011-08-11 Intrinsic Therapeutics, Inc. Bone anchoring systems
CN101835442A (zh) * 2007-09-17 2010-09-15 利纳雷斯医疗设备有限责任公司 第一和第二骨之间的人工关节支撑件
US20090082822A1 (en) * 2007-09-20 2009-03-26 Osman Said G Transpedicular, Extrapedicular and Transcorporeal Approaches to the Intervertebral Discs
US8540772B2 (en) * 2007-09-20 2013-09-24 Said G. Osman Transpedicular, extrapedicular and transcorporeal partial disc replacement
US8162994B2 (en) * 2007-10-22 2012-04-24 Flexuspine, Inc. Posterior stabilization system with isolated, dual dampener systems
US8182514B2 (en) * 2007-10-22 2012-05-22 Flexuspine, Inc. Dampener system for a posterior stabilization system with a fixed length elongated member
US8267965B2 (en) * 2007-10-22 2012-09-18 Flexuspine, Inc. Spinal stabilization systems with dynamic interbody devices
US8523912B2 (en) * 2007-10-22 2013-09-03 Flexuspine, Inc. Posterior stabilization systems with shared, dual dampener systems
US8187330B2 (en) 2007-10-22 2012-05-29 Flexuspine, Inc. Dampener system for a posterior stabilization system with a variable length elongated member
US8157844B2 (en) * 2007-10-22 2012-04-17 Flexuspine, Inc. Dampener system for a posterior stabilization system with a variable length elongated member
US8556949B2 (en) 2007-11-14 2013-10-15 DePuy Synthes Products, LLC Hybrid bone fixation element and methods of using the same
US7947784B2 (en) 2007-11-16 2011-05-24 Zimmer, Inc. Reactive compounding of hydrogels
US8591584B2 (en) * 2007-11-19 2013-11-26 Nuvasive, Inc. Textile-based plate implant and related methods
US8034362B2 (en) 2008-01-04 2011-10-11 Zimmer, Inc. Chemical composition of hydrogels for use as articulating surfaces
US20090177206A1 (en) * 2008-01-08 2009-07-09 Zimmer Spine, Inc. Instruments, implants, and methods for fixation of vertebral compression fractures
US9005288B2 (en) 2008-01-09 2015-04-14 Providence Medical Techonlogy, Inc. Methods and apparatus for accessing and treating the facet joint
US8551173B2 (en) 2008-01-17 2013-10-08 DePuy Synthes Products, LLC Expandable intervertebral implant and associated method of manufacturing the same
US8202316B2 (en) * 2008-01-29 2012-06-19 Ledergerber Walter J Modulating buttress saline mammary prosthesis
US20090198331A1 (en) * 2008-02-01 2009-08-06 Kesten Randy J Implantable prosthesis with open cell flow regulation
US8487021B2 (en) 2008-02-01 2013-07-16 Dfine, Inc. Bone treatment systems and methods
US9445854B2 (en) 2008-02-01 2016-09-20 Dfine, Inc. Bone treatment systems and methods
US20090198329A1 (en) 2008-02-01 2009-08-06 Kesten Randy J Breast implant with internal flow dampening
US8992620B2 (en) 2008-12-10 2015-03-31 Coalign Innovations, Inc. Adjustable distraction cage with linked locking mechanisms
US8740912B2 (en) 2008-02-27 2014-06-03 Ilion Medical Llc Tools for performing less invasive orthopedic joint procedures
US20090222096A1 (en) * 2008-02-28 2009-09-03 Warsaw Orthopedic, Inc. Multi-compartment expandable devices and methods for intervertebral disc expansion and augmentation
US8202299B2 (en) 2008-03-19 2012-06-19 Collabcom II, LLC Interspinous implant, tools and methods of implanting
US8333804B1 (en) * 2008-03-27 2012-12-18 Spinelogik, Inc. Intervertebral fusion device and method of use
US20100049251A1 (en) * 2008-03-28 2010-02-25 Kuslich Stephen D Method and device for interspinous process fusion
US8377135B1 (en) 2008-03-31 2013-02-19 Nuvasive, Inc. Textile-based surgical implant and related methods
KR20110003475A (ko) 2008-04-05 2011-01-12 신세스 게엠바하 팽창성 추간 임플란트
US9180416B2 (en) 2008-04-21 2015-11-10 Dfine, Inc. System for use in bone cement preparation and delivery
US20090270873A1 (en) 2008-04-24 2009-10-29 Fabian Henry F Spine surgery method and inserter
US8470045B2 (en) * 2008-05-05 2013-06-25 K2M, Inc. Endplate for an intervertebral prosthesis and prosthesis incorporating the same
US20090297603A1 (en) * 2008-05-29 2009-12-03 Abhijeet Joshi Interspinous dynamic stabilization system with anisotropic hydrogels
CN102036613B (zh) * 2008-05-30 2012-10-10 斯恩蒂斯有限公司 气球辅助环带修复
US8361152B2 (en) 2008-06-06 2013-01-29 Providence Medical Technology, Inc. Facet joint implants and delivery tools
US9381049B2 (en) 2008-06-06 2016-07-05 Providence Medical Technology, Inc. Composite spinal facet implant with textured surfaces
US9333086B2 (en) 2008-06-06 2016-05-10 Providence Medical Technology, Inc. Spinal facet cage implant
WO2010030994A2 (en) * 2008-06-06 2010-03-18 Providence Medical Technology, Inc. Cervical distraction/implant delivery device
US11224521B2 (en) 2008-06-06 2022-01-18 Providence Medical Technology, Inc. Cervical distraction/implant delivery device
US8267966B2 (en) 2008-06-06 2012-09-18 Providence Medical Technology, Inc. Facet joint implants and delivery tools
CA2725811A1 (en) 2008-06-06 2009-12-10 Providence Medical Technology, Inc. Facet joint implants and delivery tools
NL1035724C2 (nl) * 2008-07-18 2010-01-22 Univ Eindhoven Tech Prothese omvattende een kern uit een gel-materiaal met een woven omhulling en een werkwijze voor het vervaardigen hiervan en de toepassing hiervan.
US9364338B2 (en) 2008-07-23 2016-06-14 Resspond Spinal Systems Modular nucleus pulposus prosthesis
JP5462874B2 (ja) * 2008-07-23 2014-04-02 マック アイ マルバーグ モジュール化された髄核補綴物
US8075537B2 (en) * 2008-08-15 2011-12-13 Oxyband Technologies, Inc. Multiple cell therapeutic diffusion device
US8187333B2 (en) * 2008-09-18 2012-05-29 Mayer Peter L Intervertebral disc prosthesis and method for implanting and explanting
US8814937B2 (en) 2008-09-18 2014-08-26 Peter L. Mayer Intervertebral disc prosthesis, method for assembling, method for implanting prosthesis, and method for explanting
US9675390B2 (en) 2008-10-10 2017-06-13 Peter Forsell Composition, method and device for stabilizing implanted hydraulic devices
US8163022B2 (en) 2008-10-14 2012-04-24 Anulex Technologies, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
US8623056B2 (en) * 2008-10-23 2014-01-07 Linares Medical Devices, Llc Support insert associated with spinal vertebrae
US7805920B2 (en) * 2008-11-13 2010-10-05 The Toro Company Lawn mower having steeply inclined exit tunnel and battery access through rear face of mower cutting deck
EP2389126A4 (en) * 2008-12-31 2013-10-30 Spineology Inc SYSTEM AND METHOD FOR PERCUTANEOUS SPINAL ARTHRODESIS
US8721723B2 (en) 2009-01-12 2014-05-13 Globus Medical, Inc. Expandable vertebral prosthesis
US9101475B2 (en) * 2009-02-12 2015-08-11 Warsaw Orthopedic, Inc. Segmented delivery system
US8535327B2 (en) 2009-03-17 2013-09-17 Benvenue Medical, Inc. Delivery apparatus for use with implantable medical devices
US9526620B2 (en) 2009-03-30 2016-12-27 DePuy Synthes Products, Inc. Zero profile spinal fusion cage
US20110112373A1 (en) * 2009-11-10 2011-05-12 Trans1 Inc. Soft tissue access apparatus and methods for spinal surgery
US9168138B2 (en) 2009-12-09 2015-10-27 DePuy Synthes Products, Inc. Aspirating implants and method of bony regeneration
US9393129B2 (en) 2009-12-10 2016-07-19 DePuy Synthes Products, Inc. Bellows-like expandable interbody fusion cage
US8652153B2 (en) 2010-01-11 2014-02-18 Anulex Technologies, Inc. Intervertebral disc annulus repair system and bone anchor delivery tool
US9427324B1 (en) 2010-02-22 2016-08-30 Spinelogik, Inc. Intervertebral fusion device and method of use
US8449615B2 (en) 2010-04-18 2013-05-28 F.I.S.H., Llc Intervertebral implants having hydromagnetic joints
JP5008164B2 (ja) * 2010-04-21 2012-08-22 保夫 敷波 自立型バイオミメティック人工椎間板
US8876870B2 (en) * 2010-04-27 2014-11-04 Adnan Iqbal Qureshi Intraspinal device deployed through percutaneous approach into subarachnoid or intradural space of vertebral canal to protect spinal cord from external compression
US8906097B2 (en) 2010-06-02 2014-12-09 Spinecraft, LLC Intervertebral implant facilitating unilateral placement, instruments and methods
US9907560B2 (en) 2010-06-24 2018-03-06 DePuy Synthes Products, Inc. Flexible vertebral body shavers
US8979860B2 (en) 2010-06-24 2015-03-17 DePuy Synthes Products. LLC Enhanced cage insertion device
JP5850930B2 (ja) 2010-06-29 2016-02-03 ジンテス ゲゼルシャフト ミット ベシュレンクテル ハフツング 離反椎間インプラント
US20120029638A1 (en) * 2010-07-30 2012-02-02 Warsaw Orthopedic, Inc. Vertebral body replacement device configured to deliver a therapeutic substance
RU2452454C1 (ru) * 2010-09-24 2012-06-10 Валерий Викторович Педдер Устройство для бесконтактной ультразвуковой обработки биотканей
US9402732B2 (en) 2010-10-11 2016-08-02 DePuy Synthes Products, Inc. Expandable interspinous process spacer implant
US9271765B2 (en) 2011-02-24 2016-03-01 Spinal Elements, Inc. Vertebral facet joint fusion implant and method for fusion
USD724733S1 (en) 2011-02-24 2015-03-17 Spinal Elements, Inc. Interbody bone implant
US8740949B2 (en) 2011-02-24 2014-06-03 Spinal Elements, Inc. Methods and apparatus for stabilizing bone
US9707375B2 (en) 2011-03-14 2017-07-18 Rochester Medical Corporation, a subsidiary of C. R. Bard, Inc. Catheter grip and method
US8388687B2 (en) 2011-03-25 2013-03-05 Flexuspine, Inc. Interbody device insertion systems and methods
RU2479301C2 (ru) * 2011-05-27 2013-04-20 Валерий Викторович Педдер Устройство для лечения лимфедемы у больных раком молочной железы
WO2012178018A2 (en) 2011-06-24 2012-12-27 Benvenue Medical, Inc. Devices and methods for treating bone tissue
USD739935S1 (en) 2011-10-26 2015-09-29 Spinal Elements, Inc. Interbody bone implant
US9526627B2 (en) 2011-11-17 2016-12-27 Exactech, Inc. Expandable interbody device system and method
US8632593B2 (en) 2011-11-23 2014-01-21 Globus Medical, Inc. Stabilizing vertebrae with expandable spacers
US9155578B2 (en) 2012-02-28 2015-10-13 DePuy Synthes Products, Inc. Expandable fastener
US9510953B2 (en) 2012-03-16 2016-12-06 Vertebral Technologies, Inc. Modular segmented disc nucleus implant
US20130282121A1 (en) * 2012-03-22 2013-10-24 Ann Prewett Spinal facet augmentation implant and method
US9393126B2 (en) 2012-04-20 2016-07-19 Peter L. Mayer Bilaterally placed disc prosthesis for spinal implant and method of bilateral placement
US9364339B2 (en) 2012-04-30 2016-06-14 Peter L. Mayer Unilaterally placed expansile spinal prosthesis
USD732667S1 (en) 2012-10-23 2015-06-23 Providence Medical Technology, Inc. Cage spinal implant
USD745156S1 (en) 2012-10-23 2015-12-08 Providence Medical Technology, Inc. Spinal implant
US9433404B2 (en) 2012-10-31 2016-09-06 Suture Concepts Inc. Method and apparatus for closing fissures in the annulus fibrosus
US10786235B2 (en) 2012-10-31 2020-09-29 Anchor Innovation Medical, Inc. Method and apparatus for closing a fissure in the annulus of an intervertebral disc, and/or for effecting other anatomical repairs and/or fixations
US9872969B2 (en) 2012-11-20 2018-01-23 Rochester Medical Corporation, a subsidiary of C.R. Bard, Inc. Catheter in bag without additional packaging
US10092728B2 (en) 2012-11-20 2018-10-09 Rochester Medical Corporation, a subsidiary of C.R. Bard, Inc. Sheath for securing urinary catheter
WO2014105972A1 (en) 2012-12-26 2014-07-03 Koss Scott A Apparatus, kit, and method for percutaneous intervertebral disc restoration
EP2948068A4 (en) 2013-01-28 2016-09-28 Cartiva Inc SYSTEMS AND METHOD FOR ORTHOPEDIC REPAIRS
US9737294B2 (en) 2013-01-28 2017-08-22 Cartiva, Inc. Method and system for orthopedic repair
US9492288B2 (en) 2013-02-20 2016-11-15 Flexuspine, Inc. Expandable fusion device for positioning between adjacent vertebral bodies
US9717601B2 (en) 2013-02-28 2017-08-01 DePuy Synthes Products, Inc. Expandable intervertebral implant, system, kit and method
US9522070B2 (en) 2013-03-07 2016-12-20 Interventional Spine, Inc. Intervertebral implant
USD765853S1 (en) 2013-03-14 2016-09-06 Spinal Elements, Inc. Flexible elongate member with a portion configured to receive a bone anchor
WO2014159225A2 (en) 2013-03-14 2014-10-02 Baxano Surgical, Inc. Spinal implants and implantation system
US9345577B2 (en) 2013-03-14 2016-05-24 Microaire Surgical Instruments Llc Balloon implant device
US9421044B2 (en) 2013-03-14 2016-08-23 Spinal Elements, Inc. Apparatus for bone stabilization and distraction and methods of use
US9820784B2 (en) 2013-03-14 2017-11-21 Spinal Elements, Inc. Apparatus for spinal fixation and methods of use
US10085783B2 (en) 2013-03-14 2018-10-02 Izi Medical Products, Llc Devices and methods for treating bone tissue
EP3033014B1 (en) 2013-08-16 2021-04-14 Suture Concepts Inc. Apparatus for closing a fissure in the annulus of an intervertebral disc, and/or for effecting other anatomical repairs and/or fixations
US9839450B2 (en) 2013-09-27 2017-12-12 Spinal Elements, Inc. Device and method for reinforcement of a facet
US9456855B2 (en) 2013-09-27 2016-10-04 Spinal Elements, Inc. Method of placing an implant between bone portions
AT14375U1 (de) 2014-02-12 2015-10-15 Ho Med Handelsgesellschaft M B H Implantat zum Einsetzen zwischen Wirbelkörper der Wirbelsäule
US9517144B2 (en) 2014-04-24 2016-12-13 Exactech, Inc. Limited profile intervertebral implant with incorporated fastening mechanism
US10398565B2 (en) 2014-04-24 2019-09-03 Choice Spine, Llc Limited profile intervertebral implant with incorporated fastening and locking mechanism
AU2015267055B2 (en) 2014-05-27 2020-04-02 Christopher U. Phan Lateral mass fixation implant
WO2015184018A1 (en) 2014-05-28 2015-12-03 Providence Medical Technology, Inc. Lateral mass fixation system
CA2957085C (en) 2014-08-26 2023-01-17 C.R. Bard, Inc. Packaging and hydrophilic coating of urinary catheter
WO2016044432A1 (en) 2014-09-17 2016-03-24 Spinal Elements, Inc. Flexible fastening band connector
AU2016212009C1 (en) 2015-01-27 2021-02-25 Spinal Elements, Inc. Facet joint implant
US11426290B2 (en) 2015-03-06 2022-08-30 DePuy Synthes Products, Inc. Expandable intervertebral implant, system, kit and method
US10449055B2 (en) 2015-04-23 2019-10-22 Disc Fix L.L.C. Systems and methods for treatment of intervertebral disc derangements
USD841165S1 (en) 2015-10-13 2019-02-19 Providence Medical Technology, Inc. Cervical cage
WO2017066475A1 (en) 2015-10-13 2017-04-20 Providence Medical Technology, Inc. Spinal joint implant delivery device and system
EP3195833B1 (en) 2016-01-19 2022-01-12 K2M, Inc. Surgical instrument
US11510788B2 (en) 2016-06-28 2022-11-29 Eit Emerging Implant Technologies Gmbh Expandable, angularly adjustable intervertebral cages
EP3474782A2 (en) 2016-06-28 2019-05-01 Eit Emerging Implant Technologies GmbH Expandable and angularly adjustable articulating intervertebral cages
CN109640891A (zh) 2016-06-28 2019-04-16 普罗维登斯医疗技术公司 脊椎植入物及其使用方法
USD887552S1 (en) 2016-07-01 2020-06-16 Providence Medical Technology, Inc. Cervical cage
US10888433B2 (en) 2016-12-14 2021-01-12 DePuy Synthes Products, Inc. Intervertebral implant inserter and related methods
US10398563B2 (en) 2017-05-08 2019-09-03 Medos International Sarl Expandable cage
US11871968B2 (en) 2017-05-19 2024-01-16 Providence Medical Technology, Inc. Spinal fixation access and delivery system
US11344424B2 (en) 2017-06-14 2022-05-31 Medos International Sarl Expandable intervertebral implant and related methods
US10940016B2 (en) 2017-07-05 2021-03-09 Medos International Sarl Expandable intervertebral fusion cage
CN111107812A (zh) 2017-09-19 2020-05-05 C·R·巴德股份有限公司 导尿管桥接设备、系统及其方法
US11648128B2 (en) 2018-01-04 2023-05-16 Providence Medical Technology, Inc. Facet screw and delivery device
US11419733B2 (en) 2018-01-12 2022-08-23 Percheron Spine, Llc Spinal disc implant and device and method for percutaneous delivery of the spinal disc implant
US11446156B2 (en) 2018-10-25 2022-09-20 Medos International Sarl Expandable intervertebral implant, inserter instrument, and related methods
USD933230S1 (en) 2019-04-15 2021-10-12 Providence Medical Technology, Inc. Cervical cage
US11457959B2 (en) 2019-05-22 2022-10-04 Spinal Elements, Inc. Bone tie and bone tie inserter
KR20220012308A (ko) 2019-05-22 2022-02-03 스피널 엘리먼츠, 인크. 뼈 타이 및 뼈 타이 삽입기
USD911525S1 (en) 2019-06-21 2021-02-23 Providence Medical Technology, Inc. Spinal cage
US11883303B2 (en) 2019-12-30 2024-01-30 Vertebration, Inc. Spine surgery method and instrumentation
US11304733B2 (en) 2020-02-14 2022-04-19 Spinal Elements, Inc. Bone tie methods
USD945621S1 (en) 2020-02-27 2022-03-08 Providence Medical Technology, Inc. Spinal cage
US11426286B2 (en) 2020-03-06 2022-08-30 Eit Emerging Implant Technologies Gmbh Expandable intervertebral implant
US11850160B2 (en) 2021-03-26 2023-12-26 Medos International Sarl Expandable lordotic intervertebral fusion cage
US11752009B2 (en) 2021-04-06 2023-09-12 Medos International Sarl Expandable intervertebral fusion cage

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1015989A (fr) * 1950-04-05 1952-10-29 Appareil destiné à redresser la colonne vertébrale et à développer le thorax
US3426364A (en) * 1966-08-25 1969-02-11 Colorado State Univ Research F Prosthetic appliance for replacing one or more natural vertebrae
CA962806A (en) * 1970-06-04 1975-02-18 Ontario Research Foundation Surgical prosthetic device
SE391122B (sv) * 1971-01-25 1977-02-07 Cutter Lab Protes i form av en ryggradsbroskskiva och forfarande for framstellning derav
US3948254A (en) * 1971-11-08 1976-04-06 Alza Corporation Novel drug delivery device
US3875595A (en) * 1974-04-15 1975-04-08 Edward C Froning Intervertebral disc prosthesis and instruments for locating same
US3934274A (en) * 1974-10-29 1976-01-27 Hartley Jr John H Deflatable mammary augmentation prosthesis
US3987790A (en) * 1975-10-01 1976-10-26 Alza Corporation Osmotically driven fluid dispenser
US4200098A (en) * 1978-10-23 1980-04-29 Alza Corporation Osmotic system with distribution zone for dispensing beneficial agent
NL7907774A (nl) * 1979-10-22 1981-04-24 Arnoldus Theodorus Maria Van D Gewapende cervixdilatatie en weerstandsmeting-ballon.
SU895433A1 (ru) * 1980-06-04 1982-01-07 Харьковский Научно-Исследовательский Институт Ортопедии И Травматологии Им. Проф. Н.И.Ситенко Протез межпозвоночного диска
CA1146301A (en) * 1980-06-13 1983-05-17 J. David Kuntz Intervertebral disc prosthesis
US4309777A (en) * 1980-11-13 1982-01-12 Patil Arun A Artificial intervertebral disc
US4367741A (en) * 1980-12-22 1983-01-11 Alza Corporation Dispenser powered by cross-linked hydrophilic polymer grafted to hydrophilic polymer
US4485096A (en) * 1982-02-26 1984-11-27 Massachusetts Institute Of Technology Tissue-equivalent and method for preparation thereof
US4643734A (en) * 1983-05-05 1987-02-17 Hexcel Corporation Lactide/caprolactone polymer, method of making the same, composites thereof, and prostheses produced therefrom
US4554914A (en) * 1983-10-04 1985-11-26 Kapp John P Prosthetic vertebral body
US4655777A (en) * 1983-12-19 1987-04-07 Southern Research Institute Method of producing biodegradable prosthesis and products therefrom
US4685447A (en) * 1985-03-25 1987-08-11 Pmt Corporation Tissue expander system
US4636217A (en) * 1985-04-23 1987-01-13 Regents Of The University Of Minnesota Anterior spinal implant
CH671691A5 (ja) * 1987-01-08 1989-09-29 Sulzer Ag
US4772287A (en) * 1987-08-20 1988-09-20 Cedar Surgical, Inc. Prosthetic disc and method of implanting

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007530120A (ja) * 2004-03-26 2007-11-01 ヌヴァシヴ インコーポレイテッド 脊椎円板髄核置換用多孔質インプラント

Also Published As

Publication number Publication date
EP0304305A1 (en) 1989-02-22
EP0353936A1 (en) 1990-02-07
US4904260A (en) 1990-02-27
CA1324864C (en) 1993-12-07
EP0304305B1 (en) 1992-05-27
JPS6470041A (en) 1989-03-15
JPH02111359A (ja) 1990-04-24
EP0353936B1 (en) 1992-11-19
US4772287A (en) 1988-09-20

Similar Documents

Publication Publication Date Title
JP2771991B2 (ja) 人工椎間板カプセル及びその埋め込み方法
US7267690B2 (en) Interlocked modular disc nucleus prosthesis
KR100403310B1 (ko) 척추운동체절의안정화를위한팽창가능한직물삽입기구
US8092536B2 (en) Retention structure for in situ formation of an intervertebral prosthesis
US20060253198A1 (en) Multi-lumen mold for intervertebral prosthesis and method of using same
US9095449B2 (en) Method of inserting a spinal implant
JP2008531140A (ja) 椎間板修復
US20070276491A1 (en) Mold assembly for intervertebral prosthesis
US20070055375A1 (en) Methods and apparatus for reconstructing the annulus fibrosis
MXPA03003600A (es) Dispositivos y metodo para aumentar y retener nucleo pulposo.
NZ529130A (en) Inflatable device and method for reducing fractures in bone and in treating the spine
KR20020033605A (ko) 형태 변화 특성이 있는 인공보철 척추 디스크 수핵
JP4891991B2 (ja) レールベースのモジュラー式円板髄核プロテーゼ
JP2006515780A (ja) 人工髄核およびその注入方法
US11213402B2 (en) Endoscopically implantable inflatable interbody fusion device
JP2022520296A (ja) 関節スペーサー
US11583410B1 (en) Expandable total disc replacement implant
CA1321678C (en) Prosthetic disc and method of implanting
EP2140841A1 (en) Device for closing spinal disc annulus

Legal Events

Date Code Title Description
R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

LAPS Cancellation because of no payment of annual fees