JP2753297B2 - 薬学的製剤 - Google Patents

薬学的製剤

Info

Publication number
JP2753297B2
JP2753297B2 JP63502759A JP50275988A JP2753297B2 JP 2753297 B2 JP2753297 B2 JP 2753297B2 JP 63502759 A JP63502759 A JP 63502759A JP 50275988 A JP50275988 A JP 50275988A JP 2753297 B2 JP2753297 B2 JP 2753297B2
Authority
JP
Japan
Prior art keywords
pharmaceutical preparation
mixture
preparation according
component
copolymer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP63502759A
Other languages
English (en)
Japanese (ja)
Other versions
JPH01502754A (ja
Inventor
ジョーンズ，ハリー，フィリップ
マッケイ，ロバート，ジャドソン
ガムレン，マイクル，ジョン，デスモンド
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UERUKAMU FUAUNDEESHON Ltd ZA
Original Assignee
UERUKAMU FUAUNDEESHON Ltd ZA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by UERUKAMU FUAUNDEESHON Ltd ZA filed Critical UERUKAMU FUAUNDEESHON Ltd ZA
Publication of JPH01502754A publication Critical patent/JPH01502754A/ja
Application granted granted Critical
Publication of JP2753297B2 publication Critical patent/JP2753297B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP63502759A 1987-03-27 1988-03-25 薬学的製剤 Expired - Lifetime JP2753297B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878707416A GB8707416D0 (en) 1987-03-27 1987-03-27 Pharmaceutical formulations
GB8707416 1987-03-27

Publications (2)

Publication Number Publication Date
JPH01502754A JPH01502754A (ja) 1989-09-21
JP2753297B2 true JP2753297B2 (ja) 1998-05-18

Family

ID=10614818

Family Applications (1)

Application Number Title Priority Date Filing Date
JP63502759A Expired - Lifetime JP2753297B2 (ja) 1987-03-27 1988-03-25 薬学的製剤

Country Status (21)

Country Link
US (2) US4954350A (https=)
EP (1) EP0284408B1 (https=)
JP (1) JP2753297B2 (https=)
KR (1) KR960006067B1 (https=)
AT (1) ATE69725T1 (https=)
AU (1) AU606149B2 (https=)
CA (1) CA1303504C (https=)
DE (1) DE3866390D1 (https=)
DK (1) DK175660B1 (https=)
ES (1) ES2027005T3 (https=)
FI (1) FI92904C (https=)
GB (1) GB8707416D0 (https=)
GR (1) GR3003224T3 (https=)
HU (1) HU202102B (https=)
IE (1) IE61166B1 (https=)
IL (1) IL85872A (https=)
NO (1) NO175618C (https=)
NZ (1) NZ224024A (https=)
PT (1) PT87082B (https=)
WO (1) WO1988007369A1 (https=)
ZA (1) ZA882167B (https=)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2558396B2 (ja) * 1990-06-28 1996-11-27 田辺製薬株式会社 放出制御型製剤
US5188836A (en) * 1990-07-27 1993-02-23 Warner-Lambert Company Sustained release formulations
EP0520119A1 (de) * 1991-06-17 1992-12-30 Spirig Ag Pharmazeutische Präparate Neue orale Diclofenaczubereitung
US5580578A (en) * 1992-01-27 1996-12-03 Euro-Celtique, S.A. Controlled release formulations coated with aqueous dispersions of acrylic polymers
US5472712A (en) * 1991-12-24 1995-12-05 Euroceltique, S.A. Controlled-release formulations coated with aqueous dispersions of ethylcellulose
US5968551A (en) * 1991-12-24 1999-10-19 Purdue Pharma L.P. Orally administrable opioid formulations having extended duration of effect
US5681585A (en) * 1991-12-24 1997-10-28 Euro-Celtique, S.A. Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer
US7070806B2 (en) * 1992-01-27 2006-07-04 Purdue Pharma Lp Controlled release formulations coated with aqueous dispersions of acrylic polymers
US5514655A (en) * 1993-05-28 1996-05-07 Abbott Laboratories Enteral nutritional with protein system containing soy protein hydrolysate and intact protein
US6103262A (en) * 1994-01-27 2000-08-15 G. D. Searle & Company Modified-release metronidazole compositions and methods for making and using same
US6245351B1 (en) 1996-03-07 2001-06-12 Takeda Chemical Industries, Ltd. Controlled-release composition
WO1998052566A1 (en) * 1997-05-21 1998-11-26 Warner-Lambert Company Non-sedating acrivastine preparation
CA2270975C (en) 1997-07-02 2003-04-01 Euro-Celtique, S.A. Stabilized sustained release tramadol formulations
JP2000128776A (ja) * 1998-10-19 2000-05-09 Asahi Chem Ind Co Ltd フィルムコーティング顆粒およびその製造方法
FR2790668B1 (fr) * 1999-03-12 2002-07-26 D B F Granules contenant une substance vegetale et leur procede de preparation
EP1334723A4 (en) * 2000-10-23 2005-08-31 Ono Pharmaceutical Co PROLONGED RELEASE PREPARATION CONTAINING 5-ACETYL-4,6-DIMETHYL-2- (2- (4- (2-METHOXYPHENYL) PIPERAZINYL) ETHYLAMINO) PYRIMIDINE TRIHYDROCHLORIDE AS THE ACTIVE INGREDIENT
EP1385486A4 (en) * 2001-04-18 2006-05-17 Nostrum Pharmaceuticals Inc NEW COATING OF SLOW RELEASE PHARMACEUTICAL COMPOSITION
CA2476201C (en) * 2002-02-21 2009-09-01 Biovail Laboratories Incorporated Modified release formulations of at least one form of tramadol
JP2005538105A (ja) * 2002-07-25 2005-12-15 ファルマシア・コーポレーション 水不溶性ポリマーおよび水溶性の小孔形成物質からなる２層により被覆された固体剤形の製造方法
EP1981487B1 (en) * 2006-02-07 2014-06-25 Fmc Corporation Latex or pseudolatex compositions coatings and coating processes
WO2008135828A2 (en) 2007-05-03 2008-11-13 Pfizer Products Inc. Nanoparticles comprising a drug, ethylcellulose, and a bile salt
WO2008135855A2 (en) 2007-05-03 2008-11-13 Pfizer Products Inc. Nanoparticles comprising a cholesteryl ester transfer protein inhibitor and a nonionizable polymer
EP2162120B1 (en) 2007-06-04 2016-05-04 Bend Research, Inc Nanoparticles comprising a non-ionizable cellulosic polymer and an amphiphilic non-ionizable block copolymer
US9545384B2 (en) 2007-06-04 2017-01-17 Bend Research, Inc. Nanoparticles comprising drug, a non-ionizable cellulosic polymer and tocopheryl polyethylene glocol succinate
JP5283623B2 (ja) * 2007-07-17 2013-09-04 旭化成ケミカルズ株式会社 水系組成物
US9233078B2 (en) 2007-12-06 2016-01-12 Bend Research, Inc. Nanoparticles comprising a non-ionizable polymer and an Amine-functionalized methacrylate copolymer
WO2009073215A1 (en) 2007-12-06 2009-06-11 Bend Research, Inc. Pharmaceutical compositions comprising nanoparticles and a resuspending material
EP2677878B1 (en) * 2011-02-23 2016-02-17 Intercontinental Great Brands LLC Flavor pre-blends for chewing gum, methods of making flavor pre-blends and chewing gum compositions thereof
CA2758556A1 (en) * 2011-11-17 2013-05-17 Pharmascience Inc. Pharmaceutical composition of amphetamine mixed salts
CA2902911C (en) 2014-10-31 2017-06-27 Purdue Pharma Methods and compositions particularly for treatment of attention deficit disorder
US10722473B2 (en) 2018-11-19 2020-07-28 Purdue Pharma L.P. Methods and compositions particularly for treatment of attention deficit disorder

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE13486T1 (de) * 1980-11-12 1985-06-15 Ciba Geigy Ag Schnellzerfallende arzneimittel-presslinge.
EP0052075A1 (de) * 1980-11-12 1982-05-19 Ciba-Geigy Ag Körnige Arzneimittel-Retardform
SI8310221A8 (en) * 1982-02-04 1995-10-31 Wellcome Found Process for obtaining new pyridil compounds
US4562258A (en) * 1982-02-04 1985-12-31 Findlay John W A 6-[3-Amino-1-(4-tolyl)prop-1E-enyl]pyridine-2-carboxylic acid derivatives having antihistaminic activity
DE3314003A1 (de) * 1983-04-18 1984-10-18 Boehringer Ingelheim KG, 6507 Ingelheim Teilbare tablette mit verzoegerter wirkstofffreigabe und verfahren zu deren herstellung
LU85058A1 (fr) * 1983-10-24 1985-06-19 Pharlyse Comprimes pharmaceutiques a liberation prolongee,leur preparation et leur utilisation
DE3586600T2 (de) * 1984-02-10 1993-02-18 Benzon Pharma As Dosierungsform eine vielzahl mit einer diffusionshuelle ueberzogener einheiten enthaltend.
DK62184D0 (da) * 1984-02-10 1984-02-10 Benzon As Alfred Diffusionsovertrukket polydepotpraeparat
CH658188A5 (de) * 1984-03-23 1986-10-31 Ciba Geigy Ag Lagerstabile schnellzerfallende pharmazeutische presslinge.
US4871733A (en) * 1984-04-09 1989-10-03 Analgesic Associates Cough/cold mixtures comprising non-sedating antihistamine drugs
US4783465A (en) * 1984-04-09 1988-11-08 Analgesic Associates Cough/cold mixtures comprising non-sedating antihistamine drugs
GB2159715B (en) * 1984-06-04 1988-05-05 Sterwin Ag Pharmaceutical composition in sustained release unit dose form and process for its preparation
US4728512A (en) * 1985-05-06 1988-03-01 American Home Products Corporation Formulations providing three distinct releases
DE3681348D1 (de) * 1985-06-11 1991-10-17 Teijin Ltd Oral-arzneizubereitung mit retardwirkung.
GB8519310D0 (en) * 1985-07-31 1985-09-04 Zyma Sa Granular active substances
EP0212745B1 (en) * 1985-08-16 1991-04-10 The Procter & Gamble Company Drug particles having constant release
JPS6261916A (ja) * 1985-09-12 1987-03-18 Fujisawa Pharmaceut Co Ltd 持続性製剤
US4693896A (en) * 1985-10-07 1987-09-15 Fmc Corporation Ethylcellulose-coated, gastric-disintegrable aspirin tablet
SE450087B (sv) * 1985-10-11 1987-06-09 Haessle Ab Korn med kontrollerad frisettning av farmaceutiskt aktiva emnen som anbringats teckande pa ett kompakt olosligt kernmaterial
IT1188212B (it) * 1985-12-20 1988-01-07 Paolo Colombo Sistema per il rilascio a velocita' controllata di sostanze attive
US4816264A (en) * 1986-06-06 1989-03-28 Warner-Lambert Company Sustained release formulations
US4810501A (en) * 1986-06-17 1989-03-07 Warner-Lambert Company Sustained release pharmaceutical preparations
IE58401B1 (en) * 1986-06-20 1993-09-08 Elan Corp Plc Controlled absorption pharmaceutical composition
DE3775880D1 (https=) * 1986-09-18 1992-02-20 London School Of Pharmacy Innovations Ltd., London, Gb
US4800087A (en) * 1986-11-24 1989-01-24 Mehta Atul M Taste-masked pharmaceutical compositions

Also Published As

Publication number Publication date
FI885460A0 (fi) 1988-11-24
HUT50627A (en) 1990-03-28
NO175618B (https=) 1994-08-01
EP0284408A1 (en) 1988-09-28
IL85872A0 (en) 1988-09-30
HU202102B (en) 1991-02-28
DK175660B1 (da) 2005-01-10
FI92904B (fi) 1994-10-14
NO885123L (no) 1988-11-16
US4954350A (en) 1990-09-04
IE880901L (en) 1988-09-27
NO175618C (no) 1994-11-09
US5370880A (en) 1994-12-06
PT87082B (pt) 1992-07-31
AU606149B2 (en) 1991-01-31
DK662688A (da) 1988-11-25
EP0284408B1 (en) 1991-11-27
WO1988007369A1 (en) 1988-10-06
ATE69725T1 (de) 1991-12-15
KR890700344A (ko) 1989-04-24
NO885123D0 (no) 1988-11-16
PT87082A (pt) 1988-04-01
ES2027005T3 (es) 1992-05-16
IE61166B1 (en) 1994-10-05
ZA882167B (en) 1989-11-29
GB8707416D0 (en) 1987-04-29
FI885460L (fi) 1988-11-24
GR3003224T3 (en) 1993-02-17
AU1496788A (en) 1988-11-02
DE3866390D1 (de) 1992-01-09
NZ224024A (en) 1990-06-26
CA1303504C (en) 1992-06-16
JPH01502754A (ja) 1989-09-21
IL85872A (en) 1992-03-29
DK662688D0 (da) 1988-11-25
FI92904C (fi) 1995-01-25
KR960006067B1 (ko) 1996-05-08

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