JP2700088B2 - 免疫抑制剤 - Google Patents

免疫抑制剤

Info

Publication number
JP2700088B2
JP2700088B2 JP4197310A JP19731092A JP2700088B2 JP 2700088 B2 JP2700088 B2 JP 2700088B2 JP 4197310 A JP4197310 A JP 4197310A JP 19731092 A JP19731092 A JP 19731092A JP 2700088 B2 JP2700088 B2 JP 2700088B2
Authority
JP
Japan
Prior art keywords
amino acid
cysteine protease
seq
acid sequence
cysteine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP4197310A
Other languages
English (en)
Japanese (ja)
Other versions
JPH05304956A (ja
Inventor
房則 濱島
三毅夫 山本
純明 鶴
和夫 山上
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of JPH05304956A publication Critical patent/JPH05304956A/ja
Application granted granted Critical
Publication of JP2700088B2 publication Critical patent/JP2700088B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6402—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals
    • C12N9/6405—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals not being snakes
    • C12N9/641—Cysteine endopeptidases (3.4.22)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP4197310A 1991-07-25 1992-07-23 免疫抑制剤 Expired - Lifetime JP2700088B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP20854691 1991-07-25
JP3-208546 1991-07-25
JP5718992 1992-02-12
JP4-57189 1992-02-12

Publications (2)

Publication Number Publication Date
JPH05304956A JPH05304956A (ja) 1993-11-19
JP2700088B2 true JP2700088B2 (ja) 1998-01-19

Family

ID=26398209

Family Applications (1)

Application Number Title Priority Date Filing Date
JP4197310A Expired - Lifetime JP2700088B2 (ja) 1991-07-25 1992-07-23 免疫抑制剤

Country Status (3)

Country Link
US (1) US5776758A (cg-RX-API-DMAC10.html)
EP (1) EP0524834A2 (cg-RX-API-DMAC10.html)
JP (1) JP2700088B2 (cg-RX-API-DMAC10.html)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5795768A (en) * 1991-02-12 1998-08-18 Heska Corporation Filariid nematode cysteine protease proteins, nucleic acid molecules and uses thereof
US6419923B1 (en) 1991-02-12 2002-07-16 Heska Corporation Filariid nematode cysteine protease proteins, and uses thereof
JPH07505787A (ja) * 1993-02-05 1995-06-29 ダラテク・プロプライエタリー・リミテッド ファスキオラ種から取得可能なポリペプチド類，およびワクチン，処置法およびそのｄｎａ配列
GB9302302D0 (en) * 1993-02-05 1993-03-24 Pitman Moore Inc Process
US6281345B1 (en) 1994-05-26 2001-08-28 Heska Corporation Parasite astacin metalloendopeptidase nucleic acid molecules and uses thereof
WO1995032988A1 (en) * 1994-05-26 1995-12-07 Heska Corporation Novel parasite protease genes and proteins
US6265198B1 (en) 1994-05-26 2001-07-24 Heska Corporation Parasite astacin metalloendopeptidase proteins
JPH09121858A (ja) * 1995-11-06 1997-05-13 Fusanori Hamashima 免疫的寛容誘導剤
KR980008240A (ko) * 1996-07-27 1998-04-30 최윤 치료용 생체 벡터
DE19726254C2 (de) * 1997-06-20 1999-10-21 Mucos Pharma Gmbh & Co Toleranzinduktion durch Proteasen
EP1749534B1 (en) * 1997-12-31 2013-08-21 University Of Iowa Research Foundation Use of parasitic biological agents from for prevention and control of inflammatory bowel disease
WO2002094228A1 (en) * 2001-05-23 2002-11-28 David Follansbee Prevention and treatment of allergies by helminthic regulation of ige
CN102864134A (zh) * 2012-06-28 2013-01-09 江苏天福莱集团有限公司 鱿鱼内脏酶的提取工艺

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1181005A (en) * 1981-02-10 1985-01-15 Haruo Ohnishi Therapeutic agent for treatment of allergic diseases, immune complex diseases and tumors
WO1983002724A1 (fr) * 1982-02-09 1983-08-18 Ohnishi, Haruo Agent de traitement d'allergies, de maladies du complexe immunitaire et de tumeurs
EP0421022B1 (de) * 1989-10-06 1993-08-04 MUCOS EMULSIONSGESELLSCHAFT m.b.H. Verwendung katabolischer Enzyme zur Bekämpfung einer HIV-Erst-Infektion

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BIOCHEM SOC TRANSACT 19-1=1991 *
MOLECUIAR AND BIOCHEMICAL PARASITOLOGY 39-1=1990 *
PROC SOC EXP BIOL MED 145-4=1974 *

Also Published As

Publication number Publication date
EP0524834A2 (en) 1993-01-27
EP0524834A3 (cg-RX-API-DMAC10.html) 1994-03-16
JPH05304956A (ja) 1993-11-19
US5776758A (en) 1998-07-07

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Legal Events

Date Code Title Description
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 19970506