JP2026501225A5 - - Google Patents

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Publication number
JP2026501225A5
JP2026501225A5 JP2025536183A JP2025536183A JP2026501225A5 JP 2026501225 A5 JP2026501225 A5 JP 2026501225A5 JP 2025536183 A JP2025536183 A JP 2025536183A JP 2025536183 A JP2025536183 A JP 2025536183A JP 2026501225 A5 JP2026501225 A5 JP 2026501225A5
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JP
Japan
Prior art keywords
formula
compound
alkyl
independently
pharmaceutically acceptable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2025536183A
Other languages
English (en)
Japanese (ja)
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JP2026501225A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2023/084787 external-priority patent/WO2024137607A1/en
Publication of JP2026501225A publication Critical patent/JP2026501225A/ja
Publication of JP2026501225A5 publication Critical patent/JP2026501225A5/ja
Pending legal-status Critical Current

Links

JP2025536183A 2022-12-20 2023-12-19 環状ｇｍｐ－ａｍｐ合成酵素の阻害剤としてのチアジアゾール誘導体及びその使用 Pending JP2026501225A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202263433987P 2022-12-20 2022-12-20
US63/433,987 2022-12-20
US202363501320P 2023-05-10 2023-05-10
US63/501,320 2023-05-10
PCT/US2023/084787 WO2024137607A1 (en) 2022-12-20 2023-12-19 Thiadiazole derivatives as inhibitors of cyclic gmp-amp synthase and uses thereof

Publications (2)

Publication Number Publication Date
JP2026501225A JP2026501225A (ja) 2026-01-14
JP2026501225A5 true JP2026501225A5 (https=) 2026-01-27

Family

ID=89768384

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2025536183A Pending JP2026501225A (ja) 2022-12-20 2023-12-19 環状ｇｍｐ－ａｍｐ合成酵素の阻害剤としてのチアジアゾール誘導体及びその使用

Country Status (12)

Country Link
US (1) US20240270740A1 (https=)
EP (1) EP4638446A1 (https=)
JP (1) JP2026501225A (https=)
KR (1) KR20250131845A (https=)
CN (1) CN120530109A (https=)
AU (1) AU2023408761A1 (https=)
CL (1) CL2025001819A1 (https=)
CO (1) CO2025007987A2 (https=)
IL (1) IL321525A (https=)
MX (1) MX2025007158A (https=)
TW (1) TW202434205A (https=)
WO (1) WO2024137607A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2026077404A1 (zh) * 2024-10-10 2026-04-16 北京知维拓医药科技有限公司 一种杂环类化合物及其用途

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5763263A (en) 1995-11-27 1998-06-09 Dehlinger; Peter J. Method and apparatus for producing position addressable combinatorial libraries
EP2934598B1 (en) 2012-12-19 2018-04-18 Board Of Regents, The University Of Texas System Pharmaceutical targeting of a mammalian cyclic di-nucleotide signaling pathway
WO2017176812A1 (en) * 2016-04-05 2017-10-12 Immune Sensor, Llc cGAS ANTAGONIST COMPOUNDS
SG11202002218VA (en) * 2017-09-15 2020-04-29 Aduro Biotech Inc Pyrazolopyrimidinone compounds and uses thereof
BR112020016008A2 (pt) 2018-02-05 2020-12-15 The Rockefeller University Composto, método para inibir uma resposta inflamatória em um paciente, método para inibir inflamação em um paciente, método para inibir expressão de interferon ativada por dsdna em um mamífero, método para tratar metástase de câncer em um paciente e formulação farmacêutica
WO2020072492A1 (en) * 2018-10-02 2020-04-09 Baruch S. Blumberg Institute Benzamide derivatives as cgas-sting pathway agonists
JP7781074B2 (ja) * 2020-05-20 2025-12-05 エフ． ホフマン－ラ ロシュ アーゲー Ｃｇａｓ阻害トリアゾロピリミドン誘導体
EP4267571A1 (en) * 2020-12-22 2023-11-01 Novartis AG Pyrrolo[3,2-b]pyridine derivatives useful in treating conditions associated with cgas
WO2022137085A1 (en) * 2020-12-22 2022-06-30 Novartis Ag Indole derivatives useful in treating conditions associated with cgas
CA3236877A1 (en) * 2021-11-08 2023-05-11 Ventus Therapeutics U.S., Inc. Heterocyclic compounds and uses thereof
CN115160279B (zh) * 2022-07-27 2023-11-24 中国药科大学 苯并吡喃酮类化合物、药物组合物和应用

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