JP2026062630A5 - - Google Patents

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Publication number
JP2026062630A5
JP2026062630A5 JP2025192550A JP2025192550A JP2026062630A5 JP 2026062630 A5 JP2026062630 A5 JP 2026062630A5 JP 2025192550 A JP2025192550 A JP 2025192550A JP 2025192550 A JP2025192550 A JP 2025192550A JP 2026062630 A5 JP2026062630 A5 JP 2026062630A5
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Japan
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salt
sequence
dsrna agent
nucleotide
nucleotide modification
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JP2025192550A
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English (en)
Japanese (ja)
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JP2026062630A (ja
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Priority claimed from PCT/US2018/041977 external-priority patent/WO2019014530A1/en
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Publication of JP2026062630A publication Critical patent/JP2026062630A/ja
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JP2025192550A 2017-07-13 2025-11-12 乳酸脱水素酵素A(LDHA)iRNA組成物及びその使用方法 Pending JP2026062630A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201762532020P 2017-07-13 2017-07-13
US62/532,020 2017-07-13
US201762576783P 2017-10-25 2017-10-25
US62/576,783 2017-10-25
PCT/US2018/041977 WO2019014530A1 (en) 2017-07-13 2018-07-13 LACTATE DEHYDROGENASE A (LDHA) RNAI COMPOSITIONS AND METHODS OF USE
JP2020501371A JP7277432B2 (ja) 2017-07-13 2018-07-13 乳酸脱水素酵素A(LDHA)iRNA組成物及びその使用方法
JP2023076455A JP7775254B2 (ja) 2017-07-13 2023-05-08 乳酸脱水素酵素A(LDHA)iRNA組成物及びその使用方法

Related Parent Applications (1)

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JP2023076455A Division JP7775254B2 (ja) 2017-07-13 2023-05-08 乳酸脱水素酵素A(LDHA)iRNA組成物及びその使用方法

Publications (2)

Publication Number Publication Date
JP2026062630A JP2026062630A (ja) 2026-04-10
JP2026062630A5 true JP2026062630A5 (enExample) 2026-05-11

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JP2020501371A Active JP7277432B2 (ja) 2017-07-13 2018-07-13 乳酸脱水素酵素A(LDHA)iRNA組成物及びその使用方法
JP2023076455A Active JP7775254B2 (ja) 2017-07-13 2023-05-08 乳酸脱水素酵素A(LDHA)iRNA組成物及びその使用方法
JP2025192550A Pending JP2026062630A (ja) 2017-07-13 2025-11-12 乳酸脱水素酵素A(LDHA)iRNA組成物及びその使用方法

Family Applications Before (2)

Application Number Title Priority Date Filing Date
JP2020501371A Active JP7277432B2 (ja) 2017-07-13 2018-07-13 乳酸脱水素酵素A(LDHA)iRNA組成物及びその使用方法
JP2023076455A Active JP7775254B2 (ja) 2017-07-13 2023-05-08 乳酸脱水素酵素A(LDHA)iRNA組成物及びその使用方法

Country Status (6)

Country Link
US (4) US20200113927A1 (enExample)
EP (1) EP3652317A1 (enExample)
JP (3) JP7277432B2 (enExample)
AU (2) AU2018301477A1 (enExample)
CA (1) CA3069868A1 (enExample)
WO (1) WO2019014530A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
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US12600965B2 (en) 2018-11-09 2026-04-14 Alnylam Pharmaceuticals, Inc. Modified double stranded oligonucleotide
PH12022552080A1 (en) * 2020-02-10 2024-02-12 Alnylam Pharmaceuticals Inc Compositions and methods for silencing vegf-a expression
EP4121534A1 (en) 2020-03-18 2023-01-25 Alnylam Pharmaceuticals, Inc. Compositions and methods for treating subjects having a heterozygous alanine-glyoxylate aminotransferase gene (agxt) variant
EP4043018A1 (en) * 2021-02-10 2022-08-17 Charité - Universitätsmedizin Berlin Composition and method for reducing oxalate levels in patients receiving maintenance dialysis
EP4314293A1 (en) * 2021-04-01 2024-02-07 Alnylam Pharmaceuticals, Inc. Proline dehydrogenase 2 (prodh2) irna compositions and methods of use thereof
JP2024528659A (ja) 2021-07-19 2024-07-30 アルナイラム ファーマシューティカルズ, インコーポレイテッド 非原発性高シュウ酸尿症疾患または障害を有するまたは発症するリスクがある対象を治療するための方法および組成物
WO2025184301A1 (en) * 2024-02-29 2025-09-04 Arrowhead Pharmaceuticals, Inc. Rnai agents for dual inhibition of expression of apolipoprotein c-iii (apoc3) and proprotein convertase subtilisin kexin 9 (pcsk9), compositions thereof, and methods of use

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