JP2026062630A5 - - Google Patents

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Publication number
JP2026062630A5
JP2026062630A5 JP2025192550A JP2025192550A JP2026062630A5 JP 2026062630 A5 JP2026062630 A5 JP 2026062630A5 JP 2025192550 A JP2025192550 A JP 2025192550A JP 2025192550 A JP2025192550 A JP 2025192550A JP 2026062630 A5 JP2026062630 A5 JP 2026062630A5
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Japan
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salt
sequence
dsrna agent
nucleotide
nucleotide modification
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JP2025192550A
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Japanese (ja)
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JP2026062630A (ja
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Priority claimed from PCT/US2018/041977 external-priority patent/WO2019014530A1/en
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Publication of JP2026062630A publication Critical patent/JP2026062630A/ja
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JP2025192550A 2017-07-13 2025-11-12 乳酸脱水素酵素A(LDHA)iRNA組成物及びその使用方法 Pending JP2026062630A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201762532020P 2017-07-13 2017-07-13
US62/532,020 2017-07-13
US201762576783P 2017-10-25 2017-10-25
US62/576,783 2017-10-25
PCT/US2018/041977 WO2019014530A1 (en) 2017-07-13 2018-07-13 LACTATE DEHYDROGENASE A (LDHA) RNAI COMPOSITIONS AND METHODS OF USE
JP2020501371A JP7277432B2 (ja) 2017-07-13 2018-07-13 乳酸脱水素酵素A(LDHA)iRNA組成物及びその使用方法
JP2023076455A JP7775254B2 (ja) 2017-07-13 2023-05-08 乳酸脱水素酵素A(LDHA)iRNA組成物及びその使用方法

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JP2023076455A Division JP7775254B2 (ja) 2017-07-13 2023-05-08 乳酸脱水素酵素A(LDHA)iRNA組成物及びその使用方法

Publications (2)

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JP2026062630A JP2026062630A (ja) 2026-04-10
JP2026062630A5 true JP2026062630A5 (enExample) 2026-05-11

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JP2020501371A Active JP7277432B2 (ja) 2017-07-13 2018-07-13 乳酸脱水素酵素A(LDHA)iRNA組成物及びその使用方法
JP2023076455A Active JP7775254B2 (ja) 2017-07-13 2023-05-08 乳酸脱水素酵素A(LDHA)iRNA組成物及びその使用方法
JP2025192550A Pending JP2026062630A (ja) 2017-07-13 2025-11-12 乳酸脱水素酵素A(LDHA)iRNA組成物及びその使用方法

Family Applications Before (2)

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JP2020501371A Active JP7277432B2 (ja) 2017-07-13 2018-07-13 乳酸脱水素酵素A(LDHA)iRNA組成物及びその使用方法
JP2023076455A Active JP7775254B2 (ja) 2017-07-13 2023-05-08 乳酸脱水素酵素A(LDHA)iRNA組成物及びその使用方法

Country Status (6)

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US (4) US20200113927A1 (enExample)
EP (1) EP3652317A1 (enExample)
JP (3) JP7277432B2 (enExample)
AU (2) AU2018301477A1 (enExample)
CA (1) CA3069868A1 (enExample)
WO (1) WO2019014530A1 (enExample)

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WO2020097044A1 (en) 2018-11-09 2020-05-14 Alnylam Pharmaceuticals, Inc. Modified double stranded oligonucleotides
MX2022009763A (es) * 2020-02-10 2022-09-09 Alnylam Pharmaceuticals Inc Composiciones y metodos para silenciar la expresion del factor de crecimiento endotelial vascular a (vegf-a).
EP4121534A1 (en) 2020-03-18 2023-01-25 Alnylam Pharmaceuticals, Inc. Compositions and methods for treating subjects having a heterozygous alanine-glyoxylate aminotransferase gene (agxt) variant
EP4043018A1 (en) * 2021-02-10 2022-08-17 Charité - Universitätsmedizin Berlin Composition and method for reducing oxalate levels in patients receiving maintenance dialysis
WO2022212153A1 (en) * 2021-04-01 2022-10-06 Alnylam Pharmaceuticals, Inc. Proline dehydrogenase 2 (prodh2) irna compositions and methods of use thereof
WO2023003805A1 (en) 2021-07-19 2023-01-26 Alnylam Pharmaceuticals, Inc. Methods and compositions for treating subjects having or at risk of developing a non-primary hyperoxaluria disease or disorder
WO2025184301A1 (en) * 2024-02-29 2025-09-04 Arrowhead Pharmaceuticals, Inc. Rnai agents for dual inhibition of expression of apolipoprotein c-iii (apoc3) and proprotein convertase subtilisin kexin 9 (pcsk9), compositions thereof, and methods of use

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