JP2026048623A5 - - Google Patents

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Publication number
JP2026048623A5
JP2026048623A5 JP2025178584A JP2025178584A JP2026048623A5 JP 2026048623 A5 JP2026048623 A5 JP 2026048623A5 JP 2025178584 A JP2025178584 A JP 2025178584A JP 2025178584 A JP2025178584 A JP 2025178584A JP 2026048623 A5 JP2026048623 A5 JP 2026048623A5
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porcine
pig
nucleotide
cell
deletion
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JP2025178584A
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JP2026048623A (ja
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Priority claimed from JP2018506178A external-priority patent/JP2018525000A/ja
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JP2025178584A 2015-08-06 2025-10-23 改変cd163遺伝子を有する病原体抵抗性動物 Pending JP2026048623A (ja)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201562202145P 2015-08-06 2015-08-06
US62/202,145 2015-08-06
JP2018506178A JP2018525000A (ja) 2015-08-06 2016-07-22 改変cd163遺伝子を有する病原体抵抗性動物
PCT/US2016/043467 WO2017023570A1 (en) 2015-08-06 2016-07-22 Pathogen-resistant animals having modified cd163 genes
JP2021184502A JP2022033771A (ja) 2015-08-06 2021-11-12 改変cd163遺伝子を有する病原体抵抗性動物
JP2024025140A JP7808875B2 (ja) 2015-08-06 2024-02-22 改変cd163遺伝子を有する病原体抵抗性動物

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JP2024025140A Division JP7808875B2 (ja) 2015-08-06 2024-02-22 改変cd163遺伝子を有する病原体抵抗性動物

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JP2026048623A JP2026048623A (ja) 2026-03-17
JP2026048623A5 true JP2026048623A5 (https=) 2026-03-31

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ID=57943474

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JP2018506178A Withdrawn JP2018525000A (ja) 2015-08-06 2016-07-22 改変cd163遺伝子を有する病原体抵抗性動物
JP2021184502A Withdrawn JP2022033771A (ja) 2015-08-06 2021-11-12 改変cd163遺伝子を有する病原体抵抗性動物
JP2024025140A Active JP7808875B2 (ja) 2015-08-06 2024-02-22 改変cd163遺伝子を有する病原体抵抗性動物
JP2025178584A Pending JP2026048623A (ja) 2015-08-06 2025-10-23 改変cd163遺伝子を有する病原体抵抗性動物

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JP2018506178A Withdrawn JP2018525000A (ja) 2015-08-06 2016-07-22 改変cd163遺伝子を有する病原体抵抗性動物
JP2021184502A Withdrawn JP2022033771A (ja) 2015-08-06 2021-11-12 改変cd163遺伝子を有する病原体抵抗性動物
JP2024025140A Active JP7808875B2 (ja) 2015-08-06 2024-02-22 改変cd163遺伝子を有する病原体抵抗性動物

Country Status (20)

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US (5) US10091975B2 (https=)
EP (2) EP4361279A3 (https=)
JP (4) JP2018525000A (https=)
CN (2) CN109475107A (https=)
BR (1) BR112018002417A2 (https=)
DK (1) DK3331355T3 (https=)
ES (1) ES2981381T3 (https=)
FI (1) FI3331355T3 (https=)
HR (1) HRP20240908T1 (https=)
HU (1) HUE066989T2 (https=)
LT (1) LT3331355T (https=)
MX (1) MX2018001529A (https=)
PH (1) PH12018500257A1 (https=)
PL (1) PL3331355T3 (https=)
PT (1) PT3331355T (https=)
RS (1) RS65691B1 (https=)
RU (1) RU2018107842A (https=)
SI (1) SI3331355T1 (https=)
SM (1) SMT202400272T1 (https=)
WO (1) WO2017023570A1 (https=)

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KR102807016B1 (ko) 2011-05-16 2025-05-14 더 큐레이터스 오브 더 유니버시티 오브 미주리 돼지 생식기 호흡기 증후군 바이러스 내성 동물
FI3331355T3 (fi) * 2015-08-06 2024-06-17 Univ Missouri Sikojen lisääntymishäiriö- ja keuhkotulehdusoireyhtymävirukselle (PRRSV) resistentti sika ja soluja, joilla on muokattuja CD163-geenejä
GB201617559D0 (en) * 2016-10-17 2016-11-30 University Court Of The University Of Edinburgh The Swine comprising modified cd163 and associated methods
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CN107354170A (zh) * 2017-08-24 2017-11-17 中国农业科学院北京畜牧兽医研究所 一种基因敲除载体以及制备cd163基因敲除猪成纤维细胞的方法
US12060403B2 (en) 2017-10-16 2024-08-13 Kansas State University Research Foundation Methods and compositions for treating and protecting against porcine reproductive and respiratory syndrome virus
CN107937345B (zh) * 2017-11-16 2019-01-29 山东蓝思种业股份有限公司 一种制备同时敲除cd163基因和cd13基因的猪成纤维细胞的方法
KR102680060B1 (ko) * 2018-04-17 2024-07-02 더 큐레이터스 오브 더 유니버시티 오브 미주리 바이러스에 의한 감염으로부터 돼지 태아를 보호하는 방법
US11160260B2 (en) * 2018-04-17 2021-11-02 The Curators Of The University Of Missouri Methods for protecting porcine fetuses from infection with porcine reproductive and respiratory syndrome virus (PRRSV)
CN108753832A (zh) * 2018-04-20 2018-11-06 中山大学 一种利用CRISPR/Cas9编辑大白猪CD163基因的方法
KR102059503B1 (ko) 2018-07-31 2019-12-26 충북대학교 산학협력단 돼지생식기호흡기증후군 바이러스 저항성 개체 판별을 위한 단일염기다형성 마커 조성물
CN108998406B (zh) * 2018-08-03 2022-05-10 福州大学 一种人类原代培养细胞基因组编辑、定点基因敲入方法
WO2020198541A1 (en) * 2019-03-27 2020-10-01 Recombinetics, Inc. Porcine reproductive and respiratory syndrome virus (prrsv) resistant swine
CN110438155A (zh) * 2019-08-15 2019-11-12 中国农业科学院北京畜牧兽医研究所 修饰cd163基因第561位氨基酸的组合物、应用、细胞及基因编辑猪的制备方法
CN110684723B (zh) * 2019-11-21 2021-03-12 东北农业大学 一种猪卵母细胞体外成熟培养液及其制备方法与应用
GB201919294D0 (en) * 2019-12-24 2020-02-05 Eco Animal Health Ltd Antibodies or binding proteins
JP2023525263A (ja) * 2020-05-05 2023-06-15 ジーナス ピーエルシー Cd163不活化のターゲティングにより、ブタ種の健康状態を改善するための方法
CN113512534B (zh) * 2020-09-23 2024-04-23 杭州启函生物科技有限公司 用于遗传修饰和靶向的组合物和方法
CN116348063A (zh) * 2020-10-15 2023-06-27 Abs全球公司 猪的选性精液和其使用方法
CN112094866B (zh) * 2020-11-10 2021-05-11 北京首农未来生物科技有限公司 一种利用SpRY-Cas9系统制备CD163基因编辑猪的方法
EP4426830A1 (en) * 2021-11-01 2024-09-11 Sigma-Aldrich Co. LLC Electroporation enhancers for crispr-cas systems
JP2023129028A (ja) 2022-03-04 2023-09-14 三井化学株式会社 無電解めっき用プライマー組成物、積層体及びその製造方法
CN114774468B (zh) * 2022-04-20 2022-12-20 温氏食品集团股份有限公司 一种等位基因分子标记及抗蓝耳病猪群体组建方法
US20240358007A1 (en) * 2023-04-30 2024-10-31 Vincenzo Michael Biella High Efficiency Beef Cattle Having Modified ACTN3 Genes
CN116671491B (zh) * 2023-07-04 2024-01-23 四川省畜牧科学研究院 一种南江黄羊的种羊选育方法
CN119979720B (zh) * 2025-02-26 2025-09-23 中国农业科学院北京畜牧兽医研究所 猪精液品质相关的分子标记鉴定及其应用

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