JP2025509552A5 - - Google Patents
Info
- Publication number
- JP2025509552A5 JP2025509552A5 JP2024554760A JP2024554760A JP2025509552A5 JP 2025509552 A5 JP2025509552 A5 JP 2025509552A5 JP 2024554760 A JP2024554760 A JP 2024554760A JP 2024554760 A JP2024554760 A JP 2024554760A JP 2025509552 A5 JP2025509552 A5 JP 2025509552A5
- Authority
- JP
- Japan
- Prior art keywords
- aso
- mesylphosphoamide
- molecule
- nucleotides
- rna sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202263321019P | 2022-03-17 | 2022-03-17 | |
| US63/321,019 | 2022-03-17 | ||
| PCT/US2023/015398 WO2023177808A1 (en) | 2022-03-17 | 2023-03-16 | Modified gapmer oligomers and methods of use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025509552A JP2025509552A (ja) | 2025-04-11 |
| JP2025509552A5 true JP2025509552A5 (https=) | 2026-03-25 |
Family
ID=85985283
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024554760A Pending JP2025509552A (ja) | 2022-03-17 | 2023-03-16 | 修飾ギャップマーオリゴマー及びその使用方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20230383296A1 (https=) |
| EP (1) | EP4493694A1 (https=) |
| JP (1) | JP2025509552A (https=) |
| KR (1) | KR20240158340A (https=) |
| CN (1) | CN119032175A (https=) |
| AU (1) | AU2023236560A1 (https=) |
| CA (1) | CA3255691A1 (https=) |
| TW (1) | TW202345861A (https=) |
| WO (1) | WO2023177808A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN118680948B (zh) * | 2023-10-20 | 2025-08-22 | 思合基因(北京)生物科技有限公司 | 寡核苷酸及其在抗乙型肝炎病毒中的应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030203862A1 (en) * | 1998-03-26 | 2003-10-30 | Miraglia Loren J. | Antisense modulation of MDM2 expression |
| US20150247141A1 (en) * | 2012-09-14 | 2015-09-03 | Rana Therapeutics, Inc. | Multimeric oligonucleotide compounds |
| KR101707437B1 (ko) * | 2012-09-21 | 2017-02-16 | 고꾸리쯔 다이가꾸 호우징 오사까 다이가꾸 | 구아니딘 가교를 갖는 인공 뉴클레오시드 및 올리고뉴클레오티드 |
| GB201408623D0 (en) * | 2014-05-15 | 2014-07-02 | Santaris Pharma As | Oligomers and oligomer conjugates |
| TW201718618A (zh) * | 2015-09-18 | 2017-06-01 | 田邊三菱製藥股份有限公司 | 架橋型核酸GuNA,其製造方法,及中間體化合物 |
| US20210052631A1 (en) * | 2015-09-25 | 2021-02-25 | Ionis Pharmaceuticals, Inc. | Conjugated antisense compounds and their use |
| PE20211783A1 (es) | 2018-11-08 | 2021-09-08 | Aligos Therapeutics Inc | Polimeros oligonucleotidos que inhiben el transporte de antigenos y metodos |
| SG11202112741XA (en) * | 2019-05-31 | 2021-12-30 | Aligos Therapeutics Inc | Modified gapmer oligonucleotides and methods of use |
| CA3189922A1 (en) * | 2020-07-28 | 2022-02-03 | Ionis Pharmaceuticals, Inc. | Compounds and methods for reducing app expression |
-
2023
- 2023-03-16 KR KR1020247033852A patent/KR20240158340A/ko active Pending
- 2023-03-16 EP EP23716725.9A patent/EP4493694A1/en active Pending
- 2023-03-16 WO PCT/US2023/015398 patent/WO2023177808A1/en not_active Ceased
- 2023-03-16 CA CA3255691A patent/CA3255691A1/en active Pending
- 2023-03-16 JP JP2024554760A patent/JP2025509552A/ja active Pending
- 2023-03-16 TW TW112109666A patent/TW202345861A/zh unknown
- 2023-03-16 AU AU2023236560A patent/AU2023236560A1/en active Pending
- 2023-03-16 US US18/122,433 patent/US20230383296A1/en active Pending
- 2023-03-16 CN CN202380034549.XA patent/CN119032175A/zh active Pending
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