AU2023236560A1 - Modified gapmer oligomers and methods of use thereof - Google Patents
Modified gapmer oligomers and methods of use thereof Download PDFInfo
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- AU2023236560A1 AU2023236560A1 AU2023236560A AU2023236560A AU2023236560A1 AU 2023236560 A1 AU2023236560 A1 AU 2023236560A1 AU 2023236560 A AU2023236560 A AU 2023236560A AU 2023236560 A AU2023236560 A AU 2023236560A AU 2023236560 A1 AU2023236560 A1 AU 2023236560A1
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Classifications
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| US202263321019P | 2022-03-17 | 2022-03-17 | |
| US63/321,019 | 2022-03-17 | ||
| PCT/US2023/015398 WO2023177808A1 (en) | 2022-03-17 | 2023-03-16 | Modified gapmer oligomers and methods of use thereof |
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| AU2023236560A1 true AU2023236560A1 (en) | 2024-10-03 |
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| US20030203862A1 (en) * | 1998-03-26 | 2003-10-30 | Miraglia Loren J. | Antisense modulation of MDM2 expression |
| US20150247141A1 (en) * | 2012-09-14 | 2015-09-03 | Rana Therapeutics, Inc. | Multimeric oligonucleotide compounds |
| KR101707437B1 (ko) * | 2012-09-21 | 2017-02-16 | 고꾸리쯔 다이가꾸 호우징 오사까 다이가꾸 | 구아니딘 가교를 갖는 인공 뉴클레오시드 및 올리고뉴클레오티드 |
| GB201408623D0 (en) * | 2014-05-15 | 2014-07-02 | Santaris Pharma As | Oligomers and oligomer conjugates |
| TW201718618A (zh) * | 2015-09-18 | 2017-06-01 | 田邊三菱製藥股份有限公司 | 架橋型核酸ＧｕＮＡ，其製造方法，及中間體化合物 |
| US20210052631A1 (en) * | 2015-09-25 | 2021-02-25 | Ionis Pharmaceuticals, Inc. | Conjugated antisense compounds and their use |
| PE20211783A1 (es) | 2018-11-08 | 2021-09-08 | Aligos Therapeutics Inc | Polimeros oligonucleotidos que inhiben el transporte de antigenos y metodos |
| SG11202112741XA (en) * | 2019-05-31 | 2021-12-30 | Aligos Therapeutics Inc | Modified gapmer oligonucleotides and methods of use |
| CA3189922A1 (en) * | 2020-07-28 | 2022-02-03 | Ionis Pharmaceuticals, Inc. | Compounds and methods for reducing app expression |
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| US20230383296A1 (en) | 2023-11-30 |
| CA3255691A1 (en) | 2023-09-21 |
| JP2025509552A (ja) | 2025-04-11 |
| KR20240158340A (ko) | 2024-11-04 |
| WO2023177808A1 (en) | 2023-09-21 |
| EP4493694A1 (en) | 2025-01-22 |
| CN119032175A (zh) | 2024-11-26 |
| TW202345861A (zh) | 2023-12-01 |
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