CN115698288A - 核酸、含有该核酸的药物组合物与siRNA缀合物及制备方法和用途 - Google Patents
核酸、含有该核酸的药物组合物与siRNA缀合物及制备方法和用途 Download PDFInfo
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Abstract
提供了一种抑制新型冠状病毒基因表达的siRNA及其药物组合物、缀合物、用途和试剂盒。
Description
PCT国内申请，说明书已公开。
Claims (48)
- PCT国内申请，权利要求书已公开。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2020102715447 | 2020-04-08 | ||
| CN202010271544 | 2020-04-08 | ||
| PCT/CN2021/086016 WO2021204216A1 (zh) | 2020-04-08 | 2021-04-08 | 核酸、含有该核酸的药物组合物与siRNA缀合物及制备方法和用途 |
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| Publication Number | Publication Date |
|---|---|
| CN115698288A true CN115698288A (zh) | 2023-02-03 |
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| CN202180022722.5A Pending CN115698288A (zh) | 2020-04-08 | 2021-04-08 | 核酸、含有该核酸的药物组合物与siRNA缀合物及制备方法和用途 |
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| Country | Link |
|---|---|
| CN (1) | CN115698288A (zh) |
| WO (1) | WO2021204216A1 (zh) |
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|---|---|---|---|---|
| CN114632089A (zh) * | 2020-12-16 | 2022-06-17 | 北京瑞博开拓医药科技有限公司 | 含酰基糖胺基团化合物在制备治疗新型冠状病毒肺炎药物中的应用及疾病的治疗方法 |
| US20230047473A1 (en) * | 2021-07-14 | 2023-02-16 | Toagosei Co., Ltd. | siRNA based on RNA sequence of SARS-CoV-2 and use thereof |
| EP4180527A1 (en) * | 2021-11-11 | 2023-05-17 | Hangzhou Chichuang Biotechnology Co., Ltd. | Synthesis method of targeted drug ncovshrna·2ace2 |
| WO2023198201A1 (zh) * | 2022-04-14 | 2023-10-19 | 苏州瑞博生物技术股份有限公司 | 适配体、缀合物与组合物及制备方法和用途 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US7371850B1 (en) * | 2003-08-20 | 2008-05-13 | Myriad Genetics, Inc. | Method and composition for reducing expression of ROCK-II |
| CN110945131B (zh) * | 2017-12-01 | 2024-05-28 | 苏州瑞博生物技术股份有限公司 | 一种核酸、含有该核酸的组合物与缀合物及制备方法和用途 |
-
2021
- 2021-04-08 CN CN202180022722.5A patent/CN115698288A/zh active Pending
- 2021-04-08 WO PCT/CN2021/086016 patent/WO2021204216A1/zh active Application Filing
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|---|---|
| WO2021204216A1 (zh) | 2021-10-14 |
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