JP2025503521A5 - - Google Patents
Info
- Publication number
- JP2025503521A5 JP2025503521A5 JP2024538726A JP2024538726A JP2025503521A5 JP 2025503521 A5 JP2025503521 A5 JP 2025503521A5 JP 2024538726 A JP2024538726 A JP 2024538726A JP 2024538726 A JP2024538726 A JP 2024538726A JP 2025503521 A5 JP2025503521 A5 JP 2025503521A5
- Authority
- JP
- Japan
- Prior art keywords
- compound according
- alkyl
- unsubstituted
- membered
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163295657P | 2021-12-31 | 2021-12-31 | |
| US63/295,657 | 2021-12-31 | ||
| PCT/US2022/053976 WO2023129512A1 (en) | 2021-12-31 | 2022-12-23 | Bicyclic inhibitors of nicotinamide n-methyltransferase, compositions and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025503521A JP2025503521A (ja) | 2025-02-04 |
| JP2025503521A5 true JP2025503521A5 (https=) | 2025-12-23 |
Family
ID=87000165
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024538726A Pending JP2025503521A (ja) | 2021-12-31 | 2022-12-23 | ニコチンアミドｎ－メチルトランスフェラーゼの二環式阻害剤、その組成物および使用 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20250368638A1 (https=) |
| EP (1) | EP4456892A4 (https=) |
| JP (1) | JP2025503521A (https=) |
| CN (1) | CN119110724A (https=) |
| WO (1) | WO2023129512A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021163683A1 (en) | 2020-02-14 | 2021-08-19 | President And Fellows Of Harvard College | Inhibitors of nicotinamide n-methyltransferase, compositions and uses thereof |
| WO2025129168A1 (en) * | 2023-12-15 | 2025-06-19 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Triazolone inhibitors of nicotinamide n-methyltransferase and their therapeutic uses |
| TW202545926A (zh) | 2024-01-12 | 2025-12-01 | 瑞典商阿斯特捷利康公司 | 作為菸鹼醯胺ｎ—甲基轉移酶抑制劑的哌啶衍生物 |
| CN119143652B (zh) * | 2024-09-13 | 2025-11-28 | 山东大学 | 一种手性2位双取代吲哚啉化合物及其合成方法与应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW201908293A (zh) * | 2017-07-12 | 2019-03-01 | 美商必治妥美雅史谷比公司 | 作為rock抑制劑之5員及雙環雜環醯胺 |
| WO2021163683A1 (en) * | 2020-02-14 | 2021-08-19 | President And Fellows Of Harvard College | Inhibitors of nicotinamide n-methyltransferase, compositions and uses thereof |
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2022
- 2022-12-23 EP EP22917267.1A patent/EP4456892A4/en active Pending
- 2022-12-23 CN CN202280092678.XA patent/CN119110724A/zh active Pending
- 2022-12-23 US US18/725,593 patent/US20250368638A1/en active Pending
- 2022-12-23 JP JP2024538726A patent/JP2025503521A/ja active Pending
- 2022-12-23 WO PCT/US2022/053976 patent/WO2023129512A1/en not_active Ceased