JP2025121900A5 - - Google Patents

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Publication number
JP2025121900A5
JP2025121900A5 JP2025061960A JP2025061960A JP2025121900A5 JP 2025121900 A5 JP2025121900 A5 JP 2025121900A5 JP 2025061960 A JP2025061960 A JP 2025061960A JP 2025061960 A JP2025061960 A JP 2025061960A JP 2025121900 A5 JP2025121900 A5 JP 2025121900A5
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JP
Japan
Prior art keywords
lipase
recombinant
pharmaceutical composition
composition
recombinant lipase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2025061960A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025121900A (ja
Filing date
Publication date
Priority claimed from JP2022513058A external-priority patent/JP7699107B2/ja
Application filed filed Critical
Publication of JP2025121900A publication Critical patent/JP2025121900A/ja
Publication of JP2025121900A5 publication Critical patent/JP2025121900A5/ja
Pending legal-status Critical Current

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JP2025061960A 2019-08-30 2025-04-03 操作されたリパーゼ改変体 Pending JP2025121900A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201962894019P 2019-08-30 2019-08-30
US62/894,019 2019-08-30
JP2022513058A JP7699107B2 (ja) 2019-08-30 2020-08-28 操作されたリパーゼ改変体
PCT/US2020/048405 WO2021041809A1 (en) 2019-08-30 2020-08-28 Engineered lipase variants

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2022513058A Division JP7699107B2 (ja) 2019-08-30 2020-08-28 操作されたリパーゼ改変体

Publications (2)

Publication Number Publication Date
JP2025121900A JP2025121900A (ja) 2025-08-20
JP2025121900A5 true JP2025121900A5 (https=) 2025-10-02

Family

ID=74680918

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2022513058A Active JP7699107B2 (ja) 2019-08-30 2020-08-28 操作されたリパーゼ改変体
JP2025061960A Pending JP2025121900A (ja) 2019-08-30 2025-04-03 操作されたリパーゼ改変体

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2022513058A Active JP7699107B2 (ja) 2019-08-30 2020-08-28 操作されたリパーゼ改変体

Country Status (12)

Country Link
US (2) US11987823B2 (https=)
EP (2) EP4501403A3 (https=)
JP (2) JP7699107B2 (https=)
KR (1) KR20220106738A (https=)
CN (2) CN115175995B (https=)
AU (1) AU2020336468B2 (https=)
BR (1) BR112022003705A2 (https=)
CA (1) CA3152763A1 (https=)
ES (1) ES3007439T3 (https=)
IL (1) IL290978A (https=)
MX (1) MX2022002473A (https=)
WO (1) WO2021041809A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102897514B1 (ko) * 2022-03-31 2025-12-08 동아대학교 산학협력단 꿀벌 유래 지질분해 효소 및 이의 용도
CN118480529A (zh) * 2024-05-20 2024-08-13 中国海洋大学 脂肪酶Lip1897-H106Y及其编码基因与在制备DHAPG中的应用

Family Cites Families (87)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9001985D0 (sv) 1990-06-01 1990-06-01 Astra Ab New chemical products
US20060257890A1 (en) 1996-05-20 2006-11-16 Maxygen, Inc. Methods and compositions for cellular and metabolic engineering
US6165793A (en) 1996-03-25 2000-12-26 Maxygen, Inc. Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
US6395547B1 (en) 1994-02-17 2002-05-28 Maxygen, Inc. Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
US6117679A (en) 1994-02-17 2000-09-12 Maxygen, Inc. Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
US6309883B1 (en) 1994-02-17 2001-10-30 Maxygen, Inc. Methods and compositions for cellular and metabolic engineering
US6995017B1 (en) 1994-02-17 2006-02-07 Maxygen, Inc. Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
US5837458A (en) 1994-02-17 1998-11-17 Maxygen, Inc. Methods and compositions for cellular and metabolic engineering
US5928905A (en) 1995-04-18 1999-07-27 Glaxo Group Limited End-complementary polymerase reaction
US6406855B1 (en) 1994-02-17 2002-06-18 Maxygen, Inc. Methods and compositions for polypeptide engineering
US5605793A (en) 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
US5834252A (en) 1995-04-18 1998-11-10 Glaxo Group Limited End-complementary polymerase reaction
US6335160B1 (en) 1995-02-17 2002-01-01 Maxygen, Inc. Methods and compositions for polypeptide engineering
CN101659926A (zh) 1994-06-30 2010-03-03 诺沃奇梅兹有限公司 非毒性、非产毒性、非致病性镰孢属表达系统及所用启动子和终止子
FR2733249B1 (fr) * 1995-04-20 1997-06-06 Biocem Lipase gastrique de chien recombinante et polypeptides derives produits par les plantes, leurs procedes d'obtention et leurs utilisations
FI104465B (fi) 1995-06-14 2000-02-15 Valio Oy Proteiinihydrolysaatteja allergioiden hoitamiseksi tai estämiseksi, niiden valmistus ja käyttö
US6506602B1 (en) 1996-03-25 2003-01-14 Maxygen, Inc. Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
US6096548A (en) 1996-03-25 2000-08-01 Maxygen, Inc. Method for directing evolution of a virus
US6326204B1 (en) 1997-01-17 2001-12-04 Maxygen, Inc. Evolution of whole cells and organisms by recursive sequence recombination
US7148054B2 (en) 1997-01-17 2006-12-12 Maxygen, Inc. Evolution of whole cells and organisms by recursive sequence recombination
WO1998031816A1 (en) 1997-01-17 1998-07-23 Regents Of The University Of Minnesota Dna molecules and protein displaying improved triazine compound degrading ability
KR100570935B1 (ko) 1997-01-17 2006-04-13 맥시겐, 인크. 반복적 서열 재조합에 의한 전세포 및 유기체의 개량 방법
US6537746B2 (en) 1997-12-08 2003-03-25 Maxygen, Inc. Method for creating polynucleotide and polypeptide sequences
US6484105B2 (en) 1998-04-02 2002-11-19 Maxyag, Inc. Method for obtaining a plant with a genetic lesion in a gene sequence
IL139093A0 (en) 1998-05-01 2001-11-25 Maxygen Inc Optimization of pest resistance genes using dna shuffling
IL140125A0 (en) 1998-06-17 2002-02-10 Maxygen Inc Method for producing polynucleotides with desired properties
US6365408B1 (en) 1998-06-19 2002-04-02 Maxygen, Inc. Methods of evolving a polynucleotides by mutagenesis and recombination
JP2002522072A (ja) 1998-08-12 2002-07-23 マキシジェン, インコーポレイテッド 工業用化学薬品の製造のためのモノオキシゲナーゼ遺伝子のdnaシャッフリング。
JP2002526107A (ja) 1998-10-07 2002-08-20 マキシジェン, インコーポレイテッド マイコトキシンの解毒のための核酸を生成するためのdnaシャッフリング
WO2000028018A1 (en) 1998-11-10 2000-05-18 Maxygen, Inc. Modified adp-glucose pyrophosphorylase for improvement and optimization of plant phenotypes
JP4221100B2 (ja) 1999-01-13 2009-02-12 エルピーダメモリ株式会社 半導体装置
US6917882B2 (en) 1999-01-19 2005-07-12 Maxygen, Inc. Methods for making character strings, polynucleotides and polypeptides having desired characteristics
US6436675B1 (en) 1999-09-28 2002-08-20 Maxygen, Inc. Use of codon-varied oligonucleotide synthesis for synthetic shuffling
US6368861B1 (en) 1999-01-19 2002-04-09 Maxygen, Inc. Oligonucleotide mediated nucleic acid recombination
US6376246B1 (en) 1999-02-05 2002-04-23 Maxygen, Inc. Oligonucleotide mediated nucleic acid recombination
US6961664B2 (en) 1999-01-19 2005-11-01 Maxygen Methods of populating data structures for use in evolutionary simulations
US20070065838A1 (en) 1999-01-19 2007-03-22 Maxygen, Inc. Oligonucleotide mediated nucleic acid recombination
US7024312B1 (en) 1999-01-19 2006-04-04 Maxygen, Inc. Methods for making character strings, polynucleotides and polypeptides having desired characteristics
US8457903B1 (en) 1999-01-19 2013-06-04 Codexis Mayflower Holdings, Llc Method and/or apparatus for determining codons
US7702464B1 (en) 2001-08-21 2010-04-20 Maxygen, Inc. Method and apparatus for codon determining
ES2341217T3 (es) 1999-01-19 2010-06-17 Maxygen, Inc. Recombinacion de acidos nucleicos mediada por oligonucleotidos.
US7873477B1 (en) 2001-08-21 2011-01-18 Codexis Mayflower Holdings, Llc Method and system using systematically varied data libraries
JP2003524394A (ja) 1999-02-11 2003-08-19 マキシジェン, インコーポレイテッド ハイスループット質量分析法
AU3391900A (en) 1999-03-05 2000-09-21 Maxygen, Inc. Encryption of traits using split gene sequences
US6703240B1 (en) 1999-04-13 2004-03-09 Maxygar, Inc. Modified starch metabolism enzymes and encoding genes for improvement and optimization of plant phenotypes
US7430477B2 (en) 1999-10-12 2008-09-30 Maxygen, Inc. Methods of populating data structures for use in evolutionary simulations
US6519065B1 (en) 1999-11-05 2003-02-11 Jds Fitel Inc. Chromatic dispersion compensation device
US6686515B1 (en) 1999-11-23 2004-02-03 Maxygen, Inc. Homologous recombination in plants
IL150291A0 (en) 2000-01-11 2002-12-01 Maxygen Inc Integrated systems and methods for diversity generation and screening
US20010046493A1 (en) 2000-02-24 2001-11-29 Alex Margolin Lipase-containing composition and methods of use thereof
EP1272967A2 (en) 2000-03-30 2003-01-08 Maxygen, Inc. In silico cross-over site selection
JP2004508011A (ja) 2000-04-03 2004-03-18 マキシジェン, インコーポレイテッド スブチリシン変異体
US6858422B2 (en) 2000-07-13 2005-02-22 Codexis, Inc. Lipase genes
JP5319865B2 (ja) 2002-03-01 2013-10-16 コデクシス メイフラワー ホールディングス, エルエルシー 機能的生体分子を同定する方法、システム、およびソフトウェア
US7747391B2 (en) 2002-03-01 2010-06-29 Maxygen, Inc. Methods, systems, and software for identifying functional biomolecules
US20050084907A1 (en) 2002-03-01 2005-04-21 Maxygen, Inc. Methods, systems, and software for identifying functional biomolecules
EP1488335A4 (en) 2002-03-09 2006-11-15 Maxygen Inc OPTIMIZING CROSSOVER POINTS FOR THE ADJUSTED EVOLUTION
US7020762B2 (en) 2002-12-24 2006-03-28 Intel Corporation Method and apparatus for determining a dynamic random access memory page management implementation
JP4588695B2 (ja) 2003-01-30 2010-12-01 カウンシル・オブ・サイエンティフィック・アンド・インダストリアル・リサーチ リパーゼの安定的な変異体
CA3007908A1 (en) 2003-03-07 2005-04-14 Dsm Ip Assets B.V. Hydrolases, nucleic acids encoding them and methods for making and using them
JP2007502124A (ja) 2003-08-11 2007-02-08 コデクシス, インコーポレイテッド 改良ケトレダクターゼポリペプチドおよび関連ポリヌクレオチド
PT1809320E (pt) 2004-10-14 2010-10-25 Altus Pharmaceuticals Inc Composições contendo lipase, protease e amilase para o tratamento de insuficiência pancreática
EP2886658A1 (en) 2005-03-10 2015-06-24 BASF Enzymes LLC Lyase enzymes, nucleic acids encoding them and methods for making and using them
US7531341B1 (en) 2006-06-12 2009-05-12 Biomarin Pharmaceutical Inc. Compositions of prokaryotic phenylalanine ammonia-lyase and methods of using compositions thereof
US7534595B2 (en) 2006-06-12 2009-05-19 Biomarin Pharmaceutical Inc. Compositions of prokaryotic phenylalanine ammonia-lyase and methods of using compositions thereof
UA97246C2 (ru) 2006-06-15 2012-01-25 Лаборатуа Майоли Спиндле Способ получения липазы, трансформированная клетка дрожжей yarrowia lipolytica, способная вырабатывать липазу, и ее применение
US7560263B2 (en) 2007-08-17 2009-07-14 Biomarin Pharmaceutical Inc. Compositions of prokaryotic phenylalanine ammonia-lyase and methods of treating cancer using compositions thereof
EP2250594B1 (en) 2008-02-12 2017-04-19 Codexis, Inc. Method of generating an optimized, diverse population of variants
US8504498B2 (en) 2008-02-12 2013-08-06 Codexis, Inc. Method of generating an optimized, diverse population of variants
DK3023494T3 (en) 2008-06-13 2019-02-25 Codexis Inc PROCEDURE FOR SYNTHESIS OF POLYNUCLEOTIDE VARIETIES
US20090312196A1 (en) 2008-06-13 2009-12-17 Codexis, Inc. Method of synthesizing polynucleotide variants
US8383346B2 (en) 2008-06-13 2013-02-26 Codexis, Inc. Combined automated parallel synthesis of polynucleotide variants
WO2010080835A1 (en) * 2009-01-06 2010-07-15 Curemark Llc Compositions and methods for the treatment or the prevention oral infections by e. coli
BRPI0922653B8 (pt) 2009-01-29 2021-05-25 Nordmark Arzneimittel Gmbh & Co Kg uso de uma lipase bacteriana do tipo pseudomonas em solução aquosa
ES2690542T3 (es) 2010-02-04 2018-11-21 Biomarin Pharmaceutical Inc. Método para purificar variantes de fenilalanina amoníaco-liasa procariotas
MY171837A (en) * 2010-09-14 2019-11-01 Univ Putra Malaysia Novel microorganisms producing thermostable lipase from oil contaminated sample and methods thereof
DK2726651T3 (en) 2011-06-28 2019-01-28 Codexis Inc PROTEIN INVARIANT GENERATION BY REGION SHUFFLING
US20150133698A1 (en) 2012-04-20 2015-05-14 Codexis, Inc. Production of fatty alcohols from engineered microorganisms
HUE036947T2 (hu) 2012-05-11 2018-08-28 Codexis Inc Átalakított iminreduktázok és eljárások keton- és aminvegyületek reduktív aminálására
ES2647412T3 (es) 2012-09-14 2017-12-21 REG Life Sciences, LLC Variantes enzimáticas con propiedades de éster sintasa mejoradas
US9665694B2 (en) 2013-01-31 2017-05-30 Codexis, Inc. Methods, systems, and software for identifying bio-molecules with interacting components
LT3237621T (lt) 2014-12-22 2023-09-25 Codexis, Inc. Žmogaus alfa-galaktozidazės variantai
US9821613B2 (en) 2015-07-20 2017-11-21 Bendix Commercial Vehicle Systems Llc Transmitting device with antenna
DE102015114859A1 (de) 2015-09-04 2017-03-09 Nordmark Arzneimittel Gmbh & Co. Kg Verwendung einer pharmazeutischen Zusammensetzung, enthaltend mindestens ein Verdauungsenzym, bei der künstlichen Ernährung
CN108369922B (zh) 2016-01-26 2023-03-21 应用材料公司 晶片边缘环升降解决方案
EP3645712A4 (en) 2017-06-30 2021-07-07 Codexis, Inc. T7 RNA POLYMERASE VARIANTS
WO2019185612A1 (en) 2018-03-26 2019-10-03 Basf Se Method of reducing soil water repellency

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