JP2025102836A5 - - Google Patents
Info
- Publication number
- JP2025102836A5 JP2025102836A5 JP2025047199A JP2025047199A JP2025102836A5 JP 2025102836 A5 JP2025102836 A5 JP 2025102836A5 JP 2025047199 A JP2025047199 A JP 2025047199A JP 2025047199 A JP2025047199 A JP 2025047199A JP 2025102836 A5 JP2025102836 A5 JP 2025102836A5
- Authority
- JP
- Japan
- Prior art keywords
- bispecific antibody
- cancer
- pharmaceutical composition
- conjugate
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910711122.4 | 2019-08-02 | ||
| CN201910711122 | 2019-08-02 | ||
| CN201911224135.5 | 2019-12-02 | ||
| CN201911224135 | 2019-12-02 | ||
| JP2022506483A JP7655896B2 (ja) | 2019-08-02 | 2020-07-31 | 抗ｃｔｌａ４／抗ｐｄ－１二重特異性抗体及びその使用 |
| PCT/CN2020/106309 WO2021023117A1 (zh) | 2019-08-02 | 2020-07-31 | 抗ctla4-抗pd-1双特异性抗体及其用途 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022506483A Division JP7655896B2 (ja) | 2019-08-02 | 2020-07-31 | 抗ｃｔｌａ４／抗ｐｄ－１二重特異性抗体及びその使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025102836A JP2025102836A (ja) | 2025-07-08 |
| JP2025102836A5 true JP2025102836A5 (https=) | 2025-10-30 |
Family
ID=74483591
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022506483A Active JP7655896B2 (ja) | 2019-08-02 | 2020-07-31 | 抗ｃｔｌａ４／抗ｐｄ－１二重特異性抗体及びその使用 |
| JP2025047199A Pending JP2025102836A (ja) | 2019-08-02 | 2025-03-21 | 抗ｃｔｌａ４／抗ｐｄ－１二重特異性抗体及びその使用 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022506483A Active JP7655896B2 (ja) | 2019-08-02 | 2020-07-31 | 抗ｃｔｌａ４／抗ｐｄ－１二重特異性抗体及びその使用 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20220275089A1 (https=) |
| EP (1) | EP4008730A4 (https=) |
| JP (2) | JP7655896B2 (https=) |
| KR (1) | KR20220053578A (https=) |
| CN (1) | CN112300286A (https=) |
| AU (1) | AU2020325350A1 (https=) |
| BR (1) | BR112022002013A2 (https=) |
| CA (1) | CA3146780A1 (https=) |
| IL (2) | IL290255B2 (https=) |
| MX (1) | MX2022001321A (https=) |
| PH (1) | PH12022550243A1 (https=) |
| WO (1) | WO2021023117A1 (https=) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106967172B (zh) | 2016-08-23 | 2019-01-08 | 康方药业有限公司 | 抗ctla4-抗pd-1 双功能抗体、其药物组合物及其用途 |
| CN109053895B (zh) | 2018-08-30 | 2020-06-09 | 中山康方生物医药有限公司 | 抗pd-1-抗vegfa的双功能抗体、其药物组合物及其用途 |
| AU2020324185A1 (en) * | 2019-08-02 | 2022-03-03 | CTTQ-Akeso (ShangHai) Biomed. Tech. Co., Ltd. | Anti-PD-1 antibody and medical use thereof |
| EP4114464A4 (en) * | 2020-03-05 | 2024-05-01 | Merck Sharp & Dohme LLC | Methods for treating cancer using a combination of a pd-1 antagonist, a ctla4 antagonist, and lenvatinib or a pharmaceutically acceptable salt thereof |
| CN118530341A (zh) * | 2021-03-12 | 2024-08-23 | 中山康方生物医药有限公司 | 提高含有免疫球蛋白Fc片段的药物的有效性的方法 |
| EP4190819A4 (en) * | 2021-03-12 | 2024-08-14 | Akeso Biopharma, Inc. | PHARMACEUTICAL COMBINATION CONTAINING BISPECIFIC ANTI-PD-1-ANTI-VEGFA ANTIBODY, AND USE THEREOF |
| BR112023018450A2 (pt) * | 2021-04-14 | 2023-11-07 | Akeso Biopharma Inc | Anticorpo monoclonal anti-cd47 e seu uso |
| CN115197325A (zh) * | 2021-04-14 | 2022-10-18 | 康方药业有限公司 | 抗体在抗肿瘤治疗中的用途 |
| IL310217A (en) * | 2021-07-23 | 2024-03-01 | Akeso Biopharma Inc | Pharmaceutical composition and use |
| KR20240153590A (ko) * | 2022-02-24 | 2024-10-23 | 아케소 파마슈티컬스, 인코포레이티드 | 항-ctla4-항-pd-1 이중특이적 항체 및 치아우라닙을 포함하는 약제학적 조성물 |
| WO2023170549A1 (en) * | 2022-03-07 | 2023-09-14 | Medimmune Llc | Treatment methods using ctla-4 and pd-1 bispecific antibodies |
| CN118946366A (zh) * | 2022-04-13 | 2024-11-12 | 齐鲁制药有限公司 | 包含抗ctla4和抗pd1的混合抗体的药物组合物及其治疗用途 |
| WO2024051223A1 (zh) | 2022-09-09 | 2024-03-14 | 中山康方生物医药有限公司 | 药物组合及用途 |
| JP2025530041A (ja) * | 2022-09-09 | 2025-09-11 | 中山康方生物医▲藥▼有限公司 | 治療用組合せ物とその使用 |
| WO2024092031A1 (en) | 2022-10-25 | 2024-05-02 | Seismic Therapeutic, Inc. | VARIANT IgG FC POLYPEPTIDES AND USES THEREOF |
| CN118272524A (zh) * | 2022-12-30 | 2024-07-02 | 康方药业有限公司 | Cd74的医药用途 |
| JP2026507907A (ja) * | 2023-03-07 | 2026-03-06 | アケソ・ファーマ・カンパニー，リミテッド | 抗ｃｔｌａ４抗ｐｄ－１二重特異性抗体を含有する医薬組成物とその使用 |
| WO2024199435A1 (zh) * | 2023-03-31 | 2024-10-03 | 上海细胞治疗集团股份有限公司 | 双特异性抗体及自分泌双特异性抗体的工程化免疫细胞 |
| AU2024251723A1 (en) * | 2023-04-10 | 2025-11-27 | Akeso Pharma Co., Ltd. | Medical use of anti-ctla4 and anti-pd-1 bispecific antibody |
| CN120361206A (zh) * | 2024-01-25 | 2025-07-25 | 中山康方生物医药有限公司 | 抗pd-1-抗vegfa的双特异性抗体的医药用途 |
| WO2025201450A1 (zh) * | 2024-03-27 | 2025-10-02 | 康方汇科(上海)生物有限公司 | 药物组合及用途 |
| WO2025232896A1 (zh) * | 2024-05-10 | 2025-11-13 | 康方汇科(上海)生物有限公司 | 药物组合及用途 |
| CN120965861B (zh) * | 2025-10-22 | 2026-02-13 | 杭州博茵生物技术有限公司 | 一种Fc效应消除的新型骨架流式抗体及其制备方法与应用 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| DE60137273D1 (de) | 2000-10-20 | 2009-02-12 | Eisai R&D Man Co Ltd | Verfahren zur Herstellung von 4-Phenoxy chinolin Derivaten |
| PL1698623T3 (pl) | 2003-12-25 | 2015-08-31 | Eisai R&D Man Co Ltd | Postać krystaliczna soli 4-(3-chloro-4-(cyklopropyloaminokarbonylo)aminofenoksy)-7-metoksy-6-chinolinokarboksamidu lub jej solwatu i sposoby ich wytwarzania |
| CN103172731A (zh) * | 2004-07-15 | 2013-06-26 | 赞科股份有限公司 | 优化的Fc变体 |
| US8148532B2 (en) | 2007-03-14 | 2012-04-03 | Guoqing Paul Chen | Spiro substituted compounds as angiogenesis inhibitors |
| CN102203132A (zh) * | 2008-08-25 | 2011-09-28 | 安普利穆尼股份有限公司 | Pd-1拮抗剂的组合物和使用方法 |
| ES2751549T3 (es) * | 2009-11-30 | 2020-04-01 | Janssen Biotech Inc | Mutantes de anticuerpos Fc con funciones efectoras ablacionadas |
| CN102958942A (zh) * | 2009-12-29 | 2013-03-06 | 新兴产品开发西雅图有限公司 | 异二聚体结合蛋白及其应用 |
| CN107207594B (zh) * | 2014-12-23 | 2019-05-07 | 百时美施贵宝公司 | 针对tigit的抗体 |
| KR102799807B1 (ko) * | 2015-12-30 | 2025-04-24 | 코디악 사이언시스 인코포레이티드 | 항체 및 이의 접합체 |
| JP6432121B2 (ja) * | 2016-03-04 | 2018-12-05 | シチュアン ケルン−バイオテック バイオファーマシューティカル カンパニー リミテッド | Ｐｄｌ−１抗体、その医薬組成物及びその使用 |
| KR102878970B1 (ko) * | 2016-08-03 | 2025-10-30 | 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 | 항-SIRPalpha 항체 요법의 대식세포 증진 효능에서 Fc 수용체 참여의 붕괴 |
| WO2018035710A1 (en) * | 2016-08-23 | 2018-03-01 | Akeso Biopharma, Inc. | Anti-ctla4 antibodies |
| CN106967172B (zh) * | 2016-08-23 | 2019-01-08 | 康方药业有限公司 | 抗ctla4-抗pd-1 双功能抗体、其药物组合物及其用途 |
| CN106977602B (zh) * | 2016-08-23 | 2018-09-25 | 中山康方生物医药有限公司 | 一种抗pd1单克隆抗体、其药物组合物及其用途 |
| CN118027200A (zh) * | 2016-12-09 | 2024-05-14 | 艾利妥 | 抗SIRPα抗体及其使用方法 |
| CN106699891B (zh) * | 2017-01-25 | 2019-04-09 | 北京天广实生物技术股份有限公司 | 一种抗pd-l1抗体、其药物组合物及其用途 |
| EP3634485A4 (en) * | 2017-06-07 | 2021-07-21 | Silverback Therapeutics, Inc. | CONJUGATES OF ANTIBODIES CONTAINING IMMUNOMODULATOR COMPOUNDS AND THEIR USES |
| CN109762068A (zh) * | 2018-08-09 | 2019-05-17 | 源道隆（苏州）医学科技有限公司 | 一种可靶向ctla4和pd-1的单基因双特异性抗体及其应用 |
-
2020
- 2020-07-31 WO PCT/CN2020/106309 patent/WO2021023117A1/zh not_active Ceased
- 2020-07-31 MX MX2022001321A patent/MX2022001321A/es unknown
- 2020-07-31 AU AU2020325350A patent/AU2020325350A1/en active Pending
- 2020-07-31 IL IL290255A patent/IL290255B2/en unknown
- 2020-07-31 CN CN202010757322.6A patent/CN112300286A/zh active Pending
- 2020-07-31 CA CA3146780A patent/CA3146780A1/en active Pending
- 2020-07-31 KR KR1020227006972A patent/KR20220053578A/ko not_active Ceased
- 2020-07-31 EP EP20850855.6A patent/EP4008730A4/en active Pending
- 2020-07-31 PH PH1/2022/550243A patent/PH12022550243A1/en unknown
- 2020-07-31 US US17/630,467 patent/US20220275089A1/en active Pending
- 2020-07-31 BR BR112022002013A patent/BR112022002013A2/pt unknown
- 2020-07-31 JP JP2022506483A patent/JP7655896B2/ja active Active
- 2020-07-31 IL IL321822A patent/IL321822A/en unknown
-
2025
- 2025-03-21 JP JP2025047199A patent/JP2025102836A/ja active Pending
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