BR112022002013A2 - Anticorpo biespecífico anti-ctla4/anti-pd-1 e uso do mesmo - Google Patents

Anticorpo biespecífico anti-ctla4/anti-pd-1 e uso do mesmo

Info

Publication number
BR112022002013A2
BR112022002013A2 BR112022002013A BR112022002013A BR112022002013A2 BR 112022002013 A2 BR112022002013 A2 BR 112022002013A2 BR 112022002013 A BR112022002013 A BR 112022002013A BR 112022002013 A BR112022002013 A BR 112022002013A BR 112022002013 A2 BR112022002013 A2 BR 112022002013A2
Authority
BR
Brazil
Prior art keywords
ctla4
antibody
bispecific
specifically
bispecific antibody
Prior art date
Application number
BR112022002013A
Other languages
English (en)
Portuguese (pt)
Inventor
Baiyong Li
Peng Zhang
Yu Xia
Zhongmin Wang
Original Assignee
Akeso Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akeso Pharmaceuticals Inc filed Critical Akeso Pharmaceuticals Inc
Publication of BR112022002013A2 publication Critical patent/BR112022002013A2/pt

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    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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  • Health & Medical Sciences (AREA)
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  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
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  • Oncology (AREA)
  • Wood Science & Technology (AREA)
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  • Diabetes (AREA)
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BR112022002013A 2019-08-02 2020-07-31 Anticorpo biespecífico anti-ctla4/anti-pd-1 e uso do mesmo BR112022002013A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN201910711122 2019-08-02
CN201911224135 2019-12-02
PCT/CN2020/106309 WO2021023117A1 (zh) 2019-08-02 2020-07-31 抗ctla4-抗pd-1双特异性抗体及其用途

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BR112022002013A2 true BR112022002013A2 (pt) 2022-03-29

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Country Status (12)

Country Link
US (1) US20220275089A1 (https=)
EP (1) EP4008730A4 (https=)
JP (2) JP7655896B2 (https=)
KR (1) KR20220053578A (https=)
CN (1) CN112300286A (https=)
AU (1) AU2020325350A1 (https=)
BR (1) BR112022002013A2 (https=)
CA (1) CA3146780A1 (https=)
IL (2) IL290255B2 (https=)
MX (1) MX2022001321A (https=)
PH (1) PH12022550243A1 (https=)
WO (1) WO2021023117A1 (https=)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106967172B (zh) 2016-08-23 2019-01-08 康方药业有限公司 抗ctla4-抗pd-1 双功能抗体、其药物组合物及其用途
CN109053895B (zh) 2018-08-30 2020-06-09 中山康方生物医药有限公司 抗pd-1-抗vegfa的双功能抗体、其药物组合物及其用途
AU2020324185A1 (en) * 2019-08-02 2022-03-03 CTTQ-Akeso (ShangHai) Biomed. Tech. Co., Ltd. Anti-PD-1 antibody and medical use thereof
EP4114464A4 (en) * 2020-03-05 2024-05-01 Merck Sharp & Dohme LLC Methods for treating cancer using a combination of a pd-1 antagonist, a ctla4 antagonist, and lenvatinib or a pharmaceutically acceptable salt thereof
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