JP2024546129A5 - - Google Patents

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Publication number
JP2024546129A5
JP2024546129A5 JP2024534711A JP2024534711A JP2024546129A5 JP 2024546129 A5 JP2024546129 A5 JP 2024546129A5 JP 2024534711 A JP2024534711 A JP 2024534711A JP 2024534711 A JP2024534711 A JP 2024534711A JP 2024546129 A5 JP2024546129 A5 JP 2024546129A5
Authority
JP
Japan
Prior art keywords
amino acid
acid sequence
polypeptide
seq
nos
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024534711A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024546129A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/053196 external-priority patent/WO2023114485A1/en
Publication of JP2024546129A publication Critical patent/JP2024546129A/ja
Publication of JP2024546129A5 publication Critical patent/JP2024546129A5/ja
Pending legal-status Critical Current

Links

JP2024534711A 2021-12-17 2022-12-16 アルファ-l-イズロニダーゼ酵素を含む融合タンパク質及びその方法 Pending JP2024546129A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163291283P 2021-12-17 2021-12-17
US63/291,283 2021-12-17
PCT/US2022/053196 WO2023114485A1 (en) 2021-12-17 2022-12-16 Fusion proteins comprising alpha-l-iduronidase enzymes and methods

Publications (2)

Publication Number Publication Date
JP2024546129A JP2024546129A (ja) 2024-12-17
JP2024546129A5 true JP2024546129A5 (https=) 2026-01-07

Family

ID=85175822

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024534711A Pending JP2024546129A (ja) 2021-12-17 2022-12-16 アルファ-l-イズロニダーゼ酵素を含む融合タンパク質及びその方法

Country Status (12)

Country Link
US (1) US20250136963A1 (https=)
EP (1) EP4448746A1 (https=)
JP (1) JP2024546129A (https=)
KR (1) KR20240119118A (https=)
CN (1) CN118401660A (https=)
AR (1) AR128003A1 (https=)
AU (1) AU2022415476A1 (https=)
CA (1) CA3241240A1 (https=)
IL (1) IL313553A (https=)
MX (1) MX2024007319A (https=)
TW (1) TW202340459A (https=)
WO (1) WO2023114485A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202542190A (zh) 2023-12-20 2025-11-01 美商戴納立製藥公司 包含酸性α—葡萄糖苷酶之融合蛋白及其方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20180185495A1 (en) * 2014-11-10 2018-07-05 Alexion Pharmaceuticals, Inc. Therapeutic compositions of alpha-l-iduronidase, iduronate-2-sulfatase, and alpha-galactosidase a and methods of use thereof
EA039366B1 (ru) * 2015-06-24 2022-01-19 Джей Си Ар ФАРМАСЬЮТИКАЛЗ КО., ЛТД. Антитело к рецептору трансферрина человека, проникающее через гематоэнцефалический барьер
WO2018152285A1 (en) 2017-02-17 2018-08-23 Denali Therapeutics Inc. Transferrin receptor transgenic models
CR20200129A (es) 2017-10-02 2020-08-22 Denali Therapeutics Inc Proteínas de fusión que comprenden enzimas de terapia de reemplazo de enzimas
WO2019246071A1 (en) * 2018-06-18 2019-12-26 Denali Therapeutics Inc. Fusion proteins comprising progranulin
WO2021158986A1 (en) * 2020-02-07 2021-08-12 Denali Therapeutics Inc. Methods for the treatment of hunter syndrome

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