JP2023514371A5 - - Google Patents
Info
- Publication number
- JP2023514371A5 JP2023514371A5 JP2022549653A JP2022549653A JP2023514371A5 JP 2023514371 A5 JP2023514371 A5 JP 2023514371A5 JP 2022549653 A JP2022549653 A JP 2022549653A JP 2022549653 A JP2022549653 A JP 2022549653A JP 2023514371 A5 JP2023514371 A5 JP 2023514371A5
- Authority
- JP
- Japan
- Prior art keywords
- sequence
- seq
- polypeptide
- light chain
- chain polypeptides
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062978758P | 2020-02-19 | 2020-02-19 | |
| US62/978,758 | 2020-02-19 | ||
| PCT/US2021/018705 WO2021168194A1 (en) | 2020-02-19 | 2021-02-19 | Engineered anti-her2 bispecific proteins |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023514371A JP2023514371A (ja) | 2023-04-05 |
| JP2023514371A5 true JP2023514371A5 (https=) | 2024-02-26 |
Family
ID=77391704
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022549653A Pending JP2023514371A (ja) | 2020-02-19 | 2021-02-19 | 操作された抗ｈｅｒ２二重特異性タンパク質 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20230192887A1 (https=) |
| EP (1) | EP4181950A4 (https=) |
| JP (1) | JP2023514371A (https=) |
| KR (1) | KR20220156526A (https=) |
| CN (1) | CN115361972A (https=) |
| AR (1) | AR121384A1 (https=) |
| AU (1) | AU2021224200A1 (https=) |
| BR (1) | BR112022016232A2 (https=) |
| CA (1) | CA3170338A1 (https=) |
| IL (1) | IL295729A (https=) |
| MX (1) | MX2022010161A (https=) |
| TW (1) | TW202144431A (https=) |
| WO (1) | WO2021168194A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110506055A (zh) | 2017-02-17 | 2019-11-26 | 戴纳立制药公司 | 工程改造的转铁蛋白受体结合多肽 |
| BR112021015656A2 (pt) | 2019-02-20 | 2021-10-05 | Denali Therapeutics Inc. | Anticorpos anti-trem2 e métodos de uso dos mesmos |
| EP4229192A1 (en) | 2020-10-14 | 2023-08-23 | Denali Therapeutics Inc. | Fusion proteins comprising sulfoglucosamine sulfohydrolase enzymes and methods thereof |
| WO2023038803A2 (en) * | 2021-08-25 | 2023-03-16 | Denali Therapeutics Inc. | Engineered anti-her2 bispecific proteins |
| MA71684A (fr) * | 2022-08-05 | 2025-05-30 | Janssen Biotech, Inc. | Protéines de liaison de récepteur de transferrine pour traitement de tumeurs cérébrales |
| CA3263779A1 (en) * | 2022-08-05 | 2024-02-08 | Janssen Biotech, Inc. | CD98 LINKAGE CONSTRUCTIONS FOR THE TREATMENT OF BRAIN TUMORS |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005047327A2 (en) * | 2003-11-12 | 2005-05-26 | Biogen Idec Ma Inc. | NEONATAL Fc RECEPTOR (FcRn)-BINDING POLYPEPTIDE VARIANTS, DIMERIC Fc BINDING PROTEINS AND METHODS RELATED THERETO |
| US9101674B2 (en) * | 2010-03-29 | 2015-08-11 | Vib Vzw | Targeting and in vivo imaging of tumor-associated macrophages |
| AU2014357292B2 (en) * | 2013-11-27 | 2020-06-25 | Zymeworks Bc Inc. | Bispecific antigen-binding constructs targeting HER2 |
| WO2015095412A1 (en) * | 2013-12-19 | 2015-06-25 | Zhong Wang | Bispecific antibody with two single-domain antigen-binding fragments |
| EP3083696B1 (en) * | 2013-12-20 | 2018-02-14 | F.Hoffmann-La Roche Ag | Bispecific her2 antibodies and methods of use |
| SG11201608192SA (en) * | 2014-04-11 | 2016-10-28 | Medimmune Llc | Bispecific her2 antibodies |
| CA3138083A1 (en) * | 2014-12-22 | 2016-06-30 | Systimmune, Inc. | Bispecific tetravalent antibodies and methods of making and using thereof |
| CN107531788B (zh) * | 2015-06-24 | 2022-06-21 | 豪夫迈·罗氏有限公司 | 对her2和血脑屏障受体特异性的三特异性抗体及使用方法 |
| US10457717B2 (en) * | 2017-02-17 | 2019-10-29 | Denali Therapeutics Inc. | Engineered polypeptides |
| EP3665194A4 (en) * | 2017-08-10 | 2021-07-07 | Denali Therapeutics Inc. | AFFINITY BASED METHODS OF USING TRANSFERRIN RECEPTOR BINDING PROTEINS |
| JP2021534220A (ja) * | 2018-08-22 | 2021-12-09 | デナリ セラピューティクス インコーポレイテッドDenali Therapeutics Inc. | 抗ｈｅｒ２ポリペプチド及びそれらの使用の方法 |
-
2021
- 2021-02-19 AU AU2021224200A patent/AU2021224200A1/en not_active Abandoned
- 2021-02-19 BR BR112022016232A patent/BR112022016232A2/pt unknown
- 2021-02-19 EP EP21756590.2A patent/EP4181950A4/en active Pending
- 2021-02-19 IL IL295729A patent/IL295729A/en unknown
- 2021-02-19 KR KR1020227028989A patent/KR20220156526A/ko active Pending
- 2021-02-19 AR ARP210100440A patent/AR121384A1/es unknown
- 2021-02-19 TW TW110105842A patent/TW202144431A/zh unknown
- 2021-02-19 MX MX2022010161A patent/MX2022010161A/es unknown
- 2021-02-19 WO PCT/US2021/018705 patent/WO2021168194A1/en not_active Ceased
- 2021-02-19 CN CN202180027050.7A patent/CN115361972A/zh active Pending
- 2021-02-19 JP JP2022549653A patent/JP2023514371A/ja active Pending
- 2021-02-19 CA CA3170338A patent/CA3170338A1/en active Pending
-
2022
- 2022-08-11 US US17/819,182 patent/US20230192887A1/en active Pending
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