JP2024543207A5 - - Google Patents
Info
- Publication number
- JP2024543207A5 JP2024543207A5 JP2024532769A JP2024532769A JP2024543207A5 JP 2024543207 A5 JP2024543207 A5 JP 2024543207A5 JP 2024532769 A JP2024532769 A JP 2024532769A JP 2024532769 A JP2024532769 A JP 2024532769A JP 2024543207 A5 JP2024543207 A5 JP 2024543207A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutically acceptable
- acceptable salt
- compound
- alkyl
- compound according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163285558P | 2021-12-03 | 2021-12-03 | |
| US63/285,558 | 2021-12-03 | ||
| PCT/US2022/051616 WO2023102162A1 (en) | 2021-12-03 | 2022-12-02 | Tgonovel hdac inhibitors and therapeutic use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024543207A JP2024543207A (ja) | 2024-11-19 |
| JP2024543207A5 true JP2024543207A5 (https=) | 2025-12-09 |
Family
ID=85017750
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024532769A Pending JP2024543207A (ja) | 2021-12-03 | 2022-12-02 | 新規ｈｄａｃ阻害剤及びその治療的使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US12043607B2 (https=) |
| EP (1) | EP4441033A1 (https=) |
| JP (1) | JP2024543207A (https=) |
| KR (1) | KR20240152822A (https=) |
| CN (1) | CN118715206A (https=) |
| AU (1) | AU2022402913A1 (https=) |
| CA (1) | CA3240229A1 (https=) |
| IL (1) | IL313081A (https=) |
| MX (1) | MX2024006684A (https=) |
| TW (1) | TW202332437A (https=) |
| WO (1) | WO2023102162A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2025180442A1 (zh) * | 2024-03-01 | 2025-09-04 | 贝达药业股份有限公司 | Hdac抑制剂及其在医药上的应用 |
| WO2025217209A2 (en) * | 2024-04-08 | 2025-10-16 | Tango Therapeutics, Inc. | Crystalline forms of hdac inhibitor and uses thereof |
| WO2025256527A1 (en) | 2024-06-10 | 2025-12-18 | Tango Therapeutics, Inc. | Methods of preparing hdac inhibitors |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3270960A (en) | 1964-09-11 | 1966-09-06 | Sperry Rand Corp | Fluid sensor |
| US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| WO2005030705A1 (en) | 2003-09-24 | 2005-04-07 | Methylgene, Inc. | Inhibitors of histone deacetylase |
| CA2635209A1 (en) | 2006-01-12 | 2007-08-02 | Merck & Co., Inc. | Fluorinated arylamide derivatives |
| CN101466670B (zh) * | 2006-04-07 | 2013-04-17 | 梅特希尔基因公司 | 组蛋白脱乙酰酶抑制剂 |
| CA2694297A1 (en) | 2007-08-09 | 2009-02-12 | Merck Sharp & Dohme Corp. | Silicon derivatives as histone deacetylase inhibitors |
| CN101861151B (zh) | 2007-09-14 | 2014-08-13 | 梅特希尔基因公司 | 使用组蛋白脱乙酰基酶hdac1、hdac2和/或hdac3的选择性抑制剂和微管稳定剂的癌症组合治疗 |
| NZ593447A (en) | 2008-12-03 | 2012-12-21 | Harvard College | Inhibition of hdac2 to promote memory |
| WO2011079236A1 (en) | 2009-12-22 | 2011-06-30 | The Ohio State University Research Foundation | Compositions and methods for cancer detection and treatment |
| US9145412B2 (en) | 2012-11-02 | 2015-09-29 | Acetylon Pharmaceuticals, Inc. | Selective HDAC1 and HDAC2 inhibitors |
| WO2017007756A1 (en) | 2015-07-06 | 2017-01-12 | Rodin Therapeutics, Inc | Hetero-halo inhibitors of histone deacetylase |
| CN107879975B (zh) | 2016-09-30 | 2022-07-26 | 中国科学院上海药物研究所 | 组蛋白去乙酰化酶抑制剂及其应用 |
| US10385031B2 (en) | 2016-11-23 | 2019-08-20 | Regenacy Pharmaceuticals, Llc | Substituted piperazines as selective HDAC1,2 inhibitors |
| TW201829381A (zh) | 2016-12-22 | 2018-08-16 | 美商拜奧馬林製藥公司 | 組蛋白脫乙醯基酶抑制劑 |
| HUE057849T2 (hu) | 2017-01-11 | 2022-06-28 | Alkermes Inc | Hiszton deacetiláz biciklusos gátlói |
| ES2911040T3 (es) | 2017-07-10 | 2022-05-17 | Medibiofarma S L | Nuevos derivados de heteroaril amida como inhibidores selectivos de histona deacetilasa 1 y 2 (HDAC1/2) |
| CN112105602A (zh) | 2018-03-01 | 2020-12-18 | 反应生物公司 | 基于喹啉和异喹啉的hdac抑制剂及其使用方法 |
| IL279940B2 (en) | 2018-07-13 | 2024-06-01 | Alkermes Inc | Histone deacetylase inhibitors |
| IL279920B2 (en) | 2018-07-13 | 2024-06-01 | Alkermes Inc | Bicyclic inhibitors of histone deacetylase |
| WO2020068950A1 (en) | 2018-09-25 | 2020-04-02 | Regenacy Pharmaceuticals, Llc | Hdac1,2 inhibitors |
| CA3113819A1 (en) | 2018-10-10 | 2020-04-16 | Regenacy Pharmaceuticals, Llc | Pyrimidine and pyrazine hdac1,2 inhibitors |
-
2022
- 2022-12-02 CA CA3240229A patent/CA3240229A1/en active Pending
- 2022-12-02 JP JP2024532769A patent/JP2024543207A/ja active Pending
- 2022-12-02 TW TW111146457A patent/TW202332437A/zh unknown
- 2022-12-02 AU AU2022402913A patent/AU2022402913A1/en active Pending
- 2022-12-02 IL IL313081A patent/IL313081A/en unknown
- 2022-12-02 CN CN202280087838.1A patent/CN118715206A/zh active Pending
- 2022-12-02 US US18/074,163 patent/US12043607B2/en active Active
- 2022-12-02 KR KR1020247022111A patent/KR20240152822A/ko active Pending
- 2022-12-02 MX MX2024006684A patent/MX2024006684A/es unknown
- 2022-12-02 EP EP22846975.5A patent/EP4441033A1/en active Pending
- 2022-12-02 WO PCT/US2022/051616 patent/WO2023102162A1/en not_active Ceased
-
2024
- 2024-06-11 US US18/740,064 patent/US20250136570A1/en active Pending
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