JP2025502377A5 - - Google Patents
Info
- Publication number
- JP2025502377A5 JP2025502377A5 JP2024542357A JP2024542357A JP2025502377A5 JP 2025502377 A5 JP2025502377 A5 JP 2025502377A5 JP 2024542357 A JP2024542357 A JP 2024542357A JP 2024542357 A JP2024542357 A JP 2024542357A JP 2025502377 A5 JP2025502377 A5 JP 2025502377A5
- Authority
- JP
- Japan
- Prior art keywords
- atom
- group
- hydrogen atom
- cancer
- compound according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP22305031.1A EP4212531A1 (en) | 2022-01-14 | 2022-01-14 | Azaindole derivatives and their use as erk kinase inhibitors |
| EP22305031.1 | 2022-01-14 | ||
| PCT/EP2023/050692 WO2023135233A1 (en) | 2022-01-14 | 2023-01-13 | Azaindole derivatives and their use as erk kinase inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025502377A JP2025502377A (ja) | 2025-01-24 |
| JP2025502377A5 true JP2025502377A5 (https=) | 2026-01-26 |
Family
ID=80445694
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024542357A Pending JP2025502377A (ja) | 2022-01-14 | 2023-01-13 | アザインドール誘導体、及びｅｒｋキナーゼ阻害剤としてのそれらの使用 |
Country Status (16)
| Country | Link |
|---|---|
| US (3) | US11827637B2 (https=) |
| EP (2) | EP4212531A1 (https=) |
| JP (1) | JP2025502377A (https=) |
| KR (1) | KR20240134887A (https=) |
| CN (1) | CN118541370A (https=) |
| AR (1) | AR128267A1 (https=) |
| AU (1) | AU2023207276A1 (https=) |
| CA (1) | CA3242894A1 (https=) |
| CL (1) | CL2024002070A1 (https=) |
| CO (1) | CO2024008809A2 (https=) |
| IL (1) | IL314199A (https=) |
| JO (1) | JOP20240157A1 (https=) |
| MX (1) | MX2024008629A (https=) |
| TW (1) | TW202334147A (https=) |
| UA (1) | UA130477C2 (https=) |
| WO (1) | WO2023135233A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4212531A1 (en) * | 2022-01-14 | 2023-07-19 | AGV Discovery | Azaindole derivatives and their use as erk kinase inhibitors |
| WO2025012386A1 (en) * | 2023-07-12 | 2025-01-16 | Agv Discovery | Crystalline form of (s)-1-(1-(3-chlorophenyl)-2- (dimethylamino)ethyl)-4-(5-morpholino-1h-pyrrolo[2,3- b]pyridin-3-yl)pyridin-2(1h)-one, its preparation and its use as erk kinase inhibitor |
| WO2025012357A1 (en) * | 2023-07-12 | 2025-01-16 | Ipsen Pharma | Fluorinated azaindole derivatives and their use as erk kinase inhibitors |
| CN121511244A (zh) * | 2023-07-12 | 2026-02-10 | Agv探索公司 | (s)-1-(1-(3-氯苯基)-2-(二甲氨基)乙基)-4-(5-吗啉代-1h-吡咯并[2,3-b]吡啶-3-基)吡啶-2(1h)-酮的盐，其制备及其作为erk激酶抑制剂的用途 |
| EP4588918A1 (en) | 2024-01-18 | 2025-07-23 | AGV Discovery | Synthesis of (s)-1-(1-(3-chlorophenyl)-2-(dimethylamino)ethyl)- 4-(5-morpholino-1h-pyrrolo[2,3-b]pyridin-3-yl)pyridin-2(1h)-one |
| WO2026064271A1 (en) | 2024-09-23 | 2026-03-26 | Fmc Corporation | Substituted bicyclic amide derivatives as herbicides |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI339206B (en) | 2003-09-04 | 2011-03-21 | Vertex Pharma | Compositions useful as inhibitors of protein kinases |
| UA84930C2 (ru) | 2004-05-14 | 2008-12-10 | Вертекс Фармасьютикалс Инкорпорейтед | Пиррольные соединения как ингибиторы протеинкиназ erk, их синтез и соответствующие промежуточные соединения |
| US7361764B2 (en) | 2004-07-27 | 2008-04-22 | Sgx Pharmaceuticals, Inc. | Pyrrolo-pyridine kinase modulators |
| CN100396678C (zh) | 2004-11-16 | 2008-06-25 | 财团法人工业技术研究院 | 1-苯甲基-3-(5’-羟甲基-2’-呋喃基)吲唑的吲哚类似物的合成及用途 |
| EP2038272B8 (en) | 2006-06-30 | 2013-10-23 | Sunesis Pharmaceuticals, Inc. | Pyridinonyl pdk1 inhibitors |
| AU2007275221A1 (en) | 2006-07-20 | 2008-01-24 | Allen J. Borchardt | Benzothiophene inhibitors of RHO kinase |
| EP2102189B1 (en) | 2006-12-15 | 2015-07-29 | Bristol-Myers Squibb Company | Arylpropionamide, arylacrylamide, arylpropynamide, or arylmethylurea analogs as factor xia inhibitors |
| WO2012094313A1 (en) | 2011-01-04 | 2012-07-12 | Kinentia Biosciences Llc | Pyrazole derivatives as erk inhibitors |
| EP2739143B1 (en) | 2011-08-05 | 2018-07-11 | Gary A. Flynn | Preparation and methods of use for ortho-aryl 5- membered heteroaryl-carboxamide containing multi-targeted kinase inhibitors |
| JO3215B1 (ar) | 2012-08-09 | 2018-03-08 | Phenex Pharmaceuticals Ag | حلقات غير متجانسة بها 5 ذرات تحتوي على النيتروجين بها استبدال بكربوكساميد أو سلفوناميد كمعدلات لمستقبل نووي غير محمي RORy |
| MX2015004615A (es) | 2012-10-16 | 2015-07-17 | Hoffmann La Roche | Inhibidores de serina/treonina cinasa. |
| GB2515785A (en) | 2013-07-03 | 2015-01-07 | Redx Pharma Ltd | Compounds |
| EP3247353A4 (en) | 2015-01-23 | 2018-07-04 | Confluence Life Sciences, Inc. | Heterocyclic itk inhibitors for treating inflammation and cancer |
| EP3170822A1 (en) | 2015-11-18 | 2017-05-24 | AGV Discovery | Azaindole derivatives and their use as erk kinase inhibitors |
| EP3551651B1 (en) | 2016-12-09 | 2024-03-06 | Zealand Pharma A/S | Acylated glp-1/glp-2 dual agonists |
| BR112021009430A2 (pt) * | 2018-11-16 | 2021-08-17 | California Institute Of Technology | inibidores de erk e usos dos mesmos |
| EP4212531A1 (en) * | 2022-01-14 | 2023-07-19 | AGV Discovery | Azaindole derivatives and their use as erk kinase inhibitors |
-
2022
- 2022-01-14 EP EP22305031.1A patent/EP4212531A1/en not_active Withdrawn
- 2022-12-30 TW TW111150950A patent/TW202334147A/zh unknown
-
2023
- 2023-01-13 CA CA3242894A patent/CA3242894A1/en active Pending
- 2023-01-13 UA UAA202403575A patent/UA130477C2/uk unknown
- 2023-01-13 CN CN202380016949.8A patent/CN118541370A/zh active Pending
- 2023-01-13 AU AU2023207276A patent/AU2023207276A1/en active Pending
- 2023-01-13 JP JP2024542357A patent/JP2025502377A/ja active Pending
- 2023-01-13 US US18/096,996 patent/US11827637B2/en active Active
- 2023-01-13 WO PCT/EP2023/050692 patent/WO2023135233A1/en not_active Ceased
- 2023-01-13 IL IL314199A patent/IL314199A/en unknown
- 2023-01-13 EP EP23700812.3A patent/EP4463453A1/en active Pending
- 2023-01-13 AR ARP230100088A patent/AR128267A1/es unknown
- 2023-01-13 KR KR1020247023085A patent/KR20240134887A/ko active Pending
- 2023-01-13 MX MX2024008629A patent/MX2024008629A/es unknown
- 2023-10-06 US US18/377,633 patent/US12421231B2/en active Active
-
2024
- 2024-07-03 CO CONC2024/0008809A patent/CO2024008809A2/es unknown
- 2024-07-09 CL CL2024002070A patent/CL2024002070A1/es unknown
- 2024-07-14 JO JOJO/P/2024/0157A patent/JOP20240157A1/ar unknown
-
2025
- 2025-08-28 US US19/313,201 patent/US20260042758A1/en active Pending