JP2024534991A5 - - Google Patents
Info
- Publication number
- JP2024534991A5 JP2024534991A5 JP2024515645A JP2024515645A JP2024534991A5 JP 2024534991 A5 JP2024534991 A5 JP 2024534991A5 JP 2024515645 A JP2024515645 A JP 2024515645A JP 2024515645 A JP2024515645 A JP 2024515645A JP 2024534991 A5 JP2024534991 A5 JP 2024534991A5
- Authority
- JP
- Japan
- Prior art keywords
- polynucleotide
- sequence
- nucleotides
- seq
- gene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP21306245.8 | 2021-09-10 | ||
| EP21306245 | 2021-09-10 | ||
| US202263303743P | 2022-01-27 | 2022-01-27 | |
| US63/303,743 | 2022-01-27 | ||
| PCT/EP2022/075185 WO2023036966A1 (en) | 2021-09-10 | 2022-09-09 | Dual recombinant aav8 vector system encoding isoform 5 of otoferlin and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024534991A JP2024534991A (ja) | 2024-09-26 |
| JP2024534991A5 true JP2024534991A5 (https=) | 2025-08-05 |
Family
ID=83598432
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024515645A Pending JP2024534991A (ja) | 2021-09-10 | 2022-09-09 | オトフェリンのアイソフォーム５をコードする二重組換えａａｖ８ベクター系およびその使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20250295716A1 (https=) |
| EP (1) | EP4398943A1 (https=) |
| JP (1) | JP2024534991A (https=) |
| KR (1) | KR20240053630A (https=) |
| AU (1) | AU2022344528A1 (https=) |
| CA (1) | CA3231374A1 (https=) |
| IL (1) | IL311345A (https=) |
| MX (1) | MX2024003052A (https=) |
| WO (1) | WO2023036966A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116925239B (zh) * | 2023-07-17 | 2024-10-18 | 苏州星奥拓维生物技术有限公司 | 双载体系统表达Otof基因的组合物和方法 |
| CN117305367A (zh) * | 2023-08-21 | 2023-12-29 | 复旦大学附属眼耳鼻喉科医院 | 一种表达全长耳畸蛋白的双aav载体系统及其应用 |
| TW202532649A (zh) * | 2023-12-11 | 2025-08-16 | 美商阿科奧斯公司 | 用於治療具有缺陷耳畸蛋白基因之人類個體之聽力損失的組合物及方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003059396A1 (en) | 2002-01-11 | 2003-07-24 | Sergei Zolotukhin | Adiponectin gene therapy |
| WO2006036465A2 (en) | 2004-09-03 | 2006-04-06 | University Of Florida | Compositions and methods for treating cystic fibrosis |
| WO2011075838A1 (en) | 2009-12-21 | 2011-06-30 | Audigen Inc. | Method of treating or preventing hearing loss |
| WO2013075008A1 (en) | 2011-11-16 | 2013-05-23 | University Of Florida Research Foundation Inc. | Aav dual vector systems for gene therapy |
| EP3258955A1 (en) * | 2015-02-20 | 2017-12-27 | Institut Pasteur | Prevention and/or treatment of hearing loss or impairment |
| IL325122A (en) * | 2018-02-22 | 2026-02-01 | Akouos Inc | Compositions and methods for treating non-age-related hearing impairment in humans |
| WO2020093018A1 (en) * | 2018-11-01 | 2020-05-07 | University Of Florida Research Foundation, Incorporated | A codon optimized otoferlin aav dual vector gene therapy |
| EP4295913A3 (en) * | 2019-01-18 | 2024-03-06 | Institut Pasteur | Aav-mediated gene therapy restoring the otoferlin gene |
| KR20220130093A (ko) * | 2019-10-30 | 2022-09-26 | 데시벨 테라퓨틱스, 인크. | 오토펄린 듀얼 벡터 시스템을 사용한 감각신경성 난청을 치료하기 위한 조성물 및 방법 |
| EP4294460A4 (en) * | 2021-02-19 | 2025-06-25 | Decibel Therapeutics, Inc. | Methods for treating sensorineural hearing loss using otoferlin dual vector systems |
-
2022
- 2022-09-09 WO PCT/EP2022/075185 patent/WO2023036966A1/en not_active Ceased
- 2022-09-09 JP JP2024515645A patent/JP2024534991A/ja active Pending
- 2022-09-09 US US18/690,424 patent/US20250295716A1/en active Pending
- 2022-09-09 KR KR1020247011135A patent/KR20240053630A/ko active Pending
- 2022-09-09 EP EP22785946.9A patent/EP4398943A1/en active Pending
- 2022-09-09 AU AU2022344528A patent/AU2022344528A1/en active Pending
- 2022-09-09 CA CA3231374A patent/CA3231374A1/en active Pending
- 2022-09-09 IL IL311345A patent/IL311345A/en unknown
- 2022-09-09 MX MX2024003052A patent/MX2024003052A/es unknown
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