JP2024534991A5 - - Google Patents
Info
- Publication number
- JP2024534991A5 JP2024534991A5 JP2024515645A JP2024515645A JP2024534991A5 JP 2024534991 A5 JP2024534991 A5 JP 2024534991A5 JP 2024515645 A JP2024515645 A JP 2024515645A JP 2024515645 A JP2024515645 A JP 2024515645A JP 2024534991 A5 JP2024534991 A5 JP 2024534991A5
- Authority
- JP
- Japan
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP21306245.8 | 2021-09-10 | ||
| EP21306245 | 2021-09-10 | ||
| US202263303743P | 2022-01-27 | 2022-01-27 | |
| US63/303,743 | 2022-01-27 | ||
| PCT/EP2022/075185 WO2023036966A1 (en) | 2021-09-10 | 2022-09-09 | Dual recombinant aav8 vector system encoding isoform 5 of otoferlin and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2024534991A JP2024534991A (ja) | 2024-09-26 |
| JPWO2023036966A5 JPWO2023036966A5 (https=) | 2025-08-05 |
| JP2024534991A5 true JP2024534991A5 (https=) | 2025-08-05 |
Family
ID=83598432
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024515645A Pending JP2024534991A (ja) | 2021-09-10 | 2022-09-09 | オトフェリンのアイソフォーム５をコードする二重組換えａａｖ８ベクター系およびその使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20250295716A1 (https=) |
| EP (1) | EP4398943A1 (https=) |
| JP (1) | JP2024534991A (https=) |
| KR (1) | KR20240053630A (https=) |
| AU (1) | AU2022344528A1 (https=) |
| CA (1) | CA3231374A1 (https=) |
| IL (1) | IL311345A (https=) |
| MX (1) | MX2024003052A (https=) |
| WO (1) | WO2023036966A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116925239B (zh) * | 2023-07-17 | 2024-10-18 | 苏州星奥拓维生物技术有限公司 | 双载体系统表达Otof基因的组合物和方法 |
| CN117305367A (zh) * | 2023-08-21 | 2023-12-29 | 复旦大学附属眼耳鼻喉科医院 | 一种表达全长耳畸蛋白的双aav载体系统及其应用 |
| WO2025128559A1 (en) * | 2023-12-11 | 2025-06-19 | Akouos, Inc. | Compositions and methods for treating hearing loss in a human subject having a defective otoferlin gene |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003059396A1 (en) | 2002-01-11 | 2003-07-24 | Sergei Zolotukhin | Adiponectin gene therapy |
| WO2006036465A2 (en) | 2004-09-03 | 2006-04-06 | University Of Florida | Compositions and methods for treating cystic fibrosis |
| WO2011075838A1 (en) | 2009-12-21 | 2011-06-30 | Audigen Inc. | Method of treating or preventing hearing loss |
| WO2013075008A1 (en) | 2011-11-16 | 2013-05-23 | University Of Florida Research Foundation Inc. | Aav dual vector systems for gene therapy |
| US10751385B2 (en) * | 2015-02-20 | 2020-08-25 | Institut Pasteur | Prevention and/or treatment of hearing loss or impairment |
| IL325122A (en) * | 2018-02-22 | 2026-02-01 | Akouos Inc | Compositions and methods for treating non-age-related hearing impairment in humans |
| US12188041B2 (en) * | 2018-11-01 | 2025-01-07 | University Of Florida Research Foundation, Incorporated | Codon optimized otoferlin AAV dual vector gene therapy |
| WO2020148458A1 (en) * | 2019-01-18 | 2020-07-23 | Institut Pasteur | Aav-mediated gene therapy restoring the otoferlin gene |
| CA3159549A1 (en) * | 2019-10-30 | 2021-05-06 | Decibel Therapeutics, Inc. | Compositions and methods for treating sensorineural hearing loss using otoferlin dual vector systems |
| CN117295529A (zh) * | 2021-02-19 | 2023-12-26 | 分贝治疗公司 | 使用耳畸蛋白双载体系统治疗感觉神经性听力损失的方法 |
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2022
- 2022-09-09 WO PCT/EP2022/075185 patent/WO2023036966A1/en not_active Ceased
- 2022-09-09 JP JP2024515645A patent/JP2024534991A/ja active Pending
- 2022-09-09 EP EP22785946.9A patent/EP4398943A1/en active Pending
- 2022-09-09 KR KR1020247011135A patent/KR20240053630A/ko active Pending
- 2022-09-09 IL IL311345A patent/IL311345A/en unknown
- 2022-09-09 CA CA3231374A patent/CA3231374A1/en active Pending
- 2022-09-09 MX MX2024003052A patent/MX2024003052A/es unknown
- 2022-09-09 US US18/690,424 patent/US20250295716A1/en active Pending
- 2022-09-09 AU AU2022344528A patent/AU2022344528A1/en active Pending