JP2024507837A5 - - Google Patents
Info
- Publication number
- JP2024507837A5 JP2024507837A5 JP2023550062A JP2023550062A JP2024507837A5 JP 2024507837 A5 JP2024507837 A5 JP 2024507837A5 JP 2023550062 A JP2023550062 A JP 2023550062A JP 2023550062 A JP2023550062 A JP 2023550062A JP 2024507837 A5 JP2024507837 A5 JP 2024507837A5
- Authority
- JP
- Japan
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163151589P | 2021-02-19 | 2021-02-19 | |
| US63/151,589 | 2021-02-19 | ||
| PCT/US2022/017058 WO2022178298A1 (en) | 2021-02-19 | 2022-02-18 | Methods for treating sensorineural hearing loss using otoferlin dual vector systems |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2024507837A JP2024507837A (ja) | 2024-02-21 |
| JPWO2022178298A5 JPWO2022178298A5 (https=) | 2025-02-25 |
| JP2024507837A5 true JP2024507837A5 (https=) | 2025-02-25 |
Family
ID=82931783
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023550062A Pending JP2024507837A (ja) | 2021-02-19 | 2022-02-18 | オトフェリン二重ベクター系を使用して、感音難聴を治療するための組成物 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20240148905A1 (https=) |
| EP (1) | EP4294460A4 (https=) |
| JP (1) | JP2024507837A (https=) |
| KR (1) | KR20240004253A (https=) |
| CN (1) | CN117295529A (https=) |
| MX (1) | MX2023009714A (https=) |
| WO (1) | WO2022178298A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN119410636A (zh) | 2018-04-27 | 2025-02-11 | 分贝治疗公司 | 肌球蛋白15启动子及其用途 |
| WO2020123713A1 (en) * | 2018-12-11 | 2020-06-18 | Decibel Therapeutics, Inc. | Compositions and methods for the delivery of therapeutic agents across the round window membrane |
| EP3921032A4 (en) | 2019-02-08 | 2022-11-30 | Decibel Therapeutics, Inc. | COMPOSITIONS AND METHODS FOR TREATMENT OF SENSORINEURAL HEARING LOSS USING OTOFERLIN DOUBLE VECTOR SYSTEMS |
| AU2020218547A1 (en) | 2019-02-08 | 2021-08-26 | Decibel Therapeutics, Inc. | Myosin 15 promoters and uses thereof |
| CA3159549A1 (en) | 2019-10-30 | 2021-05-06 | Decibel Therapeutics, Inc. | Compositions and methods for treating sensorineural hearing loss using otoferlin dual vector systems |
| JP7807380B2 (ja) | 2020-02-21 | 2026-01-27 | アコーオス インコーポレイテッド | ヒト対象において非加齢関連聴力障害を処置するための組成物および方法 |
| WO2023036966A1 (en) * | 2021-09-10 | 2023-03-16 | Institut Pasteur | Dual recombinant aav8 vector system encoding isoform 5 of otoferlin and uses thereof |
| CN117305367A (zh) * | 2023-08-21 | 2023-12-29 | 复旦大学附属眼耳鼻喉科医院 | 一种表达全长耳畸蛋白的双aav载体系统及其应用 |
| WO2025201333A1 (zh) * | 2024-03-28 | 2025-10-02 | 苏州星奥拓维生物技术有限公司 | 递送Otof基因的双载体系统和其用途 |
| WO2025221253A1 (en) * | 2024-04-17 | 2025-10-23 | Decibel Therapeutics, Inc. | Methods for treating sensorineural hearing loss using otoferlin dual vector systems |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2019530737A (ja) * | 2016-08-23 | 2019-10-24 | アコーオス インコーポレイテッド | ヒト対象において非加齢性聴力障害を治療するための組成物および方法 |
| IL325122A (en) * | 2018-02-22 | 2026-02-01 | Akouos Inc | Compositions and methods for treating non-age-related hearing impairment in humans |
| US11660353B2 (en) * | 2018-04-27 | 2023-05-30 | Decibel Therapeutics, Inc. | Compositions and methods for treating sensorineural hearing loss using otoferlin dual vector systems |
| US12188041B2 (en) * | 2018-11-01 | 2025-01-07 | University Of Florida Research Foundation, Incorporated | Codon optimized otoferlin AAV dual vector gene therapy |
| WO2020148458A1 (en) * | 2019-01-18 | 2020-07-23 | Institut Pasteur | Aav-mediated gene therapy restoring the otoferlin gene |
| EP3921032A4 (en) * | 2019-02-08 | 2022-11-30 | Decibel Therapeutics, Inc. | COMPOSITIONS AND METHODS FOR TREATMENT OF SENSORINEURAL HEARING LOSS USING OTOFERLIN DOUBLE VECTOR SYSTEMS |
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2022
- 2022-02-18 CN CN202280028998.9A patent/CN117295529A/zh active Pending
- 2022-02-18 WO PCT/US2022/017058 patent/WO2022178298A1/en not_active Ceased
- 2022-02-18 US US18/277,858 patent/US20240148905A1/en active Pending
- 2022-02-18 MX MX2023009714A patent/MX2023009714A/es unknown
- 2022-02-18 EP EP22757028.0A patent/EP4294460A4/en active Pending
- 2022-02-18 KR KR1020237031961A patent/KR20240004253A/ko active Pending
- 2022-02-18 JP JP2023550062A patent/JP2024507837A/ja active Pending