JP2024507837A5 - - Google Patents
Info
- Publication number
- JP2024507837A5 JP2024507837A5 JP2023550062A JP2023550062A JP2024507837A5 JP 2024507837 A5 JP2024507837 A5 JP 2024507837A5 JP 2023550062 A JP2023550062 A JP 2023550062A JP 2023550062 A JP2023550062 A JP 2023550062A JP 2024507837 A5 JP2024507837 A5 JP 2024507837A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- nucleic acid
- acid vector
- otof
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163151589P | 2021-02-19 | 2021-02-19 | |
| US63/151,589 | 2021-02-19 | ||
| PCT/US2022/017058 WO2022178298A1 (en) | 2021-02-19 | 2022-02-18 | Methods for treating sensorineural hearing loss using otoferlin dual vector systems |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024507837A JP2024507837A (ja) | 2024-02-21 |
| JP2024507837A5 true JP2024507837A5 (https=) | 2025-02-25 |
Family
ID=82931783
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023550062A Pending JP2024507837A (ja) | 2021-02-19 | 2022-02-18 | オトフェリン二重ベクター系を使用して、感音難聴を治療するための組成物 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20240148905A1 (https=) |
| EP (1) | EP4294460A4 (https=) |
| JP (1) | JP2024507837A (https=) |
| KR (1) | KR20240004253A (https=) |
| CN (1) | CN117295529A (https=) |
| MX (1) | MX2023009714A (https=) |
| WO (1) | WO2022178298A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112703016B (zh) | 2018-04-27 | 2024-11-22 | 分贝治疗公司 | 肌球蛋白15启动子及其用途 |
| US20220054640A1 (en) * | 2018-12-11 | 2022-02-24 | Decibel Therapeutics, Inc. | Compositions and methods for the delivery of therapeutic agents across the round window membrane |
| CA3129422A1 (en) | 2019-02-08 | 2020-08-13 | Decibel Therapeutics, Inc. | Myosin 15 promoters and uses thereof |
| EP3921032A4 (en) | 2019-02-08 | 2022-11-30 | Decibel Therapeutics, Inc. | COMPOSITIONS AND METHODS FOR TREATMENT OF SENSORINEURAL HEARING LOSS USING OTOFERLIN DOUBLE VECTOR SYSTEMS |
| KR20220130093A (ko) | 2019-10-30 | 2022-09-26 | 데시벨 테라퓨틱스, 인크. | 오토펄린 듀얼 벡터 시스템을 사용한 감각신경성 난청을 치료하기 위한 조성물 및 방법 |
| KR20220157944A (ko) | 2020-02-21 | 2022-11-29 | 아카우오스, 인크. | 인간 대상체에서 비-연령-연관 청각 장애를 치료하기 위한 조성물 및 방법 |
| WO2023036966A1 (en) * | 2021-09-10 | 2023-03-16 | Institut Pasteur | Dual recombinant aav8 vector system encoding isoform 5 of otoferlin and uses thereof |
| CN117305367A (zh) * | 2023-08-21 | 2023-12-29 | 复旦大学附属眼耳鼻喉科医院 | 一种表达全长耳畸蛋白的双aav载体系统及其应用 |
| WO2025201333A1 (zh) * | 2024-03-28 | 2025-10-02 | 苏州星奥拓维生物技术有限公司 | 递送Otof基因的双载体系统和其用途 |
| WO2025221253A1 (en) * | 2024-04-17 | 2025-10-23 | Decibel Therapeutics, Inc. | Methods for treating sensorineural hearing loss using otoferlin dual vector systems |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3510161A4 (en) * | 2016-08-23 | 2020-04-22 | Akouos, Inc. | COMPOSITIONS AND METHODS FOR TREATING PERSONAL HEARING LOSS IN A PERSON |
| IL325122A (en) * | 2018-02-22 | 2026-02-01 | Akouos Inc | Compositions and methods for treating non-age-related hearing impairment in humans |
| US11660353B2 (en) * | 2018-04-27 | 2023-05-30 | Decibel Therapeutics, Inc. | Compositions and methods for treating sensorineural hearing loss using otoferlin dual vector systems |
| WO2020093018A1 (en) * | 2018-11-01 | 2020-05-07 | University Of Florida Research Foundation, Incorporated | A codon optimized otoferlin aav dual vector gene therapy |
| EP4295913A3 (en) * | 2019-01-18 | 2024-03-06 | Institut Pasteur | Aav-mediated gene therapy restoring the otoferlin gene |
| EP3921032A4 (en) * | 2019-02-08 | 2022-11-30 | Decibel Therapeutics, Inc. | COMPOSITIONS AND METHODS FOR TREATMENT OF SENSORINEURAL HEARING LOSS USING OTOFERLIN DOUBLE VECTOR SYSTEMS |
-
2022
- 2022-02-18 EP EP22757028.0A patent/EP4294460A4/en active Pending
- 2022-02-18 WO PCT/US2022/017058 patent/WO2022178298A1/en not_active Ceased
- 2022-02-18 MX MX2023009714A patent/MX2023009714A/es unknown
- 2022-02-18 KR KR1020237031961A patent/KR20240004253A/ko active Pending
- 2022-02-18 US US18/277,858 patent/US20240148905A1/en active Pending
- 2022-02-18 JP JP2023550062A patent/JP2024507837A/ja active Pending
- 2022-02-18 CN CN202280028998.9A patent/CN117295529A/zh active Pending
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