JP2024517843A5 - - Google Patents

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Publication number
JP2024517843A5
JP2024517843A5 JP2023568104A JP2023568104A JP2024517843A5 JP 2024517843 A5 JP2024517843 A5 JP 2024517843A5 JP 2023568104 A JP2023568104 A JP 2023568104A JP 2023568104 A JP2023568104 A JP 2023568104A JP 2024517843 A5 JP2024517843 A5 JP 2024517843A5
Authority
JP
Japan
Prior art keywords
nucleic acid
vector
vector system
polynucleotide
signal sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023568104A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024517843A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/027870 external-priority patent/WO2022235933A2/en
Publication of JP2024517843A publication Critical patent/JP2024517843A/ja
Publication of JP2024517843A5 publication Critical patent/JP2024517843A5/ja
Pending legal-status Critical Current

Links

JP2023568104A 2021-05-05 2022-05-05 ステレオシリン二重ベクター系を使用して感音性難聴を治療するための組成物及び方法 Pending JP2024517843A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163184737P 2021-05-05 2021-05-05
US63/184,737 2021-05-05
PCT/US2022/027870 WO2022235933A2 (en) 2021-05-05 2022-05-05 Compositions and methods for treating sensorineural hearing loss using stereocilin dual vector systems

Publications (2)

Publication Number Publication Date
JP2024517843A JP2024517843A (ja) 2024-04-23
JP2024517843A5 true JP2024517843A5 (https=) 2025-05-08

Family

ID=83932494

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023568104A Pending JP2024517843A (ja) 2021-05-05 2022-05-05 ステレオシリン二重ベクター系を使用して感音性難聴を治療するための組成物及び方法

Country Status (13)

Country Link
US (1) US20240216540A1 (https=)
EP (1) EP4333905A4 (https=)
JP (1) JP2024517843A (https=)
KR (1) KR20240021166A (https=)
CN (1) CN117750983A (https=)
AU (1) AU2022271265A1 (https=)
BR (1) BR112023022833A2 (https=)
CA (1) CA3219054A1 (https=)
CL (1) CL2023003260A1 (https=)
CO (1) CO2023016804A2 (https=)
IL (1) IL308142A (https=)
MX (1) MX2023013053A (https=)
WO (1) WO2022235933A2 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020014625A1 (en) 2018-07-13 2020-01-16 Akouos, Inc. Methods of treating non-syndromic sensorineural hearing loss
US20220054640A1 (en) * 2018-12-11 2022-02-24 Decibel Therapeutics, Inc. Compositions and methods for the delivery of therapeutic agents across the round window membrane
CN116925239B (zh) * 2023-07-17 2024-10-18 苏州星奥拓维生物技术有限公司 双载体系统表达Otof基因的组合物和方法
US20260027327A1 (en) 2024-07-26 2026-01-29 Regeneron Pharmaceuticals, Inc. Otic drug delivery system and methods

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008073303A2 (en) * 2006-12-07 2008-06-19 Switchgear Genomics Transcriptional regulatory elements of biological pathways, tools, and methods
WO2020014625A1 (en) * 2018-07-13 2020-01-16 Akouos, Inc. Methods of treating non-syndromic sensorineural hearing loss
WO2020077295A1 (en) * 2018-10-11 2020-04-16 Decibel Therapeutics, Inc. Aav1 vectors and uses thereof for treatment of otic indications
EP3880827A4 (en) * 2018-11-07 2023-04-26 Akouos, Inc. COMPOSITIONS AND METHODS FOR INDUCING DIFFERENTIATION OF A HAIR CELL
EP3921032A4 (en) * 2019-02-08 2022-11-30 Decibel Therapeutics, Inc. COMPOSITIONS AND METHODS FOR TREATMENT OF SENSORINEURAL HEARING LOSS USING OTOFERLIN DOUBLE VECTOR SYSTEMS

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