JP2022549140A5 - - Google Patents
Info
- Publication number
- JP2022549140A5 JP2022549140A5 JP2022517343A JP2022517343A JP2022549140A5 JP 2022549140 A5 JP2022549140 A5 JP 2022549140A5 JP 2022517343 A JP2022517343 A JP 2022517343A JP 2022517343 A JP2022517343 A JP 2022517343A JP 2022549140 A5 JP2022549140 A5 JP 2022549140A5
- Authority
- JP
- Japan
- Prior art keywords
- pkp2
- gene therapy
- therapy vector
- therapeutic formulation
- isoform
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962903103P | 2019-09-20 | 2019-09-20 | |
| US62/903,103 | 2019-09-20 | ||
| PCT/EP2020/076290 WO2021053222A1 (en) | 2019-09-20 | 2020-09-21 | Gene therapy composition and treatment of right ventricular arrythmogenic cardiomyopathy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022549140A JP2022549140A (ja) | 2022-11-24 |
| JP2022549140A5 true JP2022549140A5 (https=) | 2023-09-22 |
Family
ID=72615856
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022517343A Pending JP2022549140A (ja) | 2019-09-20 | 2020-09-21 | 遺伝子療法組成物および不整脈源性右心室心筋症の治療 |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US20220389452A1 (https=) |
| EP (1) | EP4031672A1 (https=) |
| JP (1) | JP2022549140A (https=) |
| KR (1) | KR20220066914A (https=) |
| AU (1) | AU2020350140A1 (https=) |
| CA (1) | CA3151036A1 (https=) |
| IL (1) | IL291488A (https=) |
| TW (1) | TWI897882B (https=) |
| WO (1) | WO2021053222A1 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3947700A4 (en) | 2019-04-01 | 2023-01-04 | Tenaya Therapeutics, Inc. | Adeno-associated virus with engineered capsid |
| EP4087489B1 (en) * | 2020-01-08 | 2025-05-14 | Vitruvia Holdings Inc. | Methods and computing system for processing ultrasound image to determine health of subdermal tissue |
| EP4103214B1 (en) | 2020-02-13 | 2026-04-29 | Tenaya Therapeutics, Inc. | Gene therapy vectors for treating heart disease |
| KR20230043869A (ko) * | 2020-08-07 | 2023-03-31 | 스페이스크래프트 세븐, 엘엘씨 | Aav 벡터를 사용한 플라코필린-2(pkp2) 유전자 요법 |
| BR112023006305A2 (pt) * | 2020-10-09 | 2023-05-09 | Tenaya Therapeutics Inc | Métodos e composições de terapia gênica com placofilina-2 |
| US11781156B2 (en) * | 2020-10-09 | 2023-10-10 | Tenaya Therapeutics, Inc. | Plakophillin-2 gene therapy methods and compositions |
| AU2022239846A1 (en) * | 2021-03-19 | 2023-10-26 | Ucl Business Ltd | Gene therapy composition and treatment of right ventricular arrhythmogenic cardiomyopathy |
| CN117178057A (zh) * | 2021-04-12 | 2023-12-05 | 加利福尼亚大学董事会 | 用于致心律失常性右心室心肌病的基因治疗 |
| JP2025508743A (ja) * | 2022-02-18 | 2025-04-10 | ギンコ バイオワークス インコーポレイテッド | 不整脈原性心筋症のための遺伝子治療 |
| US20250205365A1 (en) * | 2022-03-18 | 2025-06-26 | University Of Florida Research Foundation, Incorporated | Methods and compositions for treating rbm20 related cardiomyopathy with a viral vector |
| JP2025512405A (ja) * | 2022-04-11 | 2025-04-17 | テナヤ セラピューティクス， インコーポレイテッド | プラコフィリン２遺伝子治療の処置の方法 |
| WO2024064796A2 (en) * | 2022-09-21 | 2024-03-28 | Rejuvenate Bio | Gene therapy methods for arrhythmogenic cardiomyopathy |
| TW202421788A (zh) * | 2022-09-22 | 2024-06-01 | 美商拜奧馬林製藥公司 | 用ａａｖ基因療法載體治療致心律不整性心肌病 |
| CN116064612A (zh) * | 2022-11-17 | 2023-05-05 | 百世诺（北京）医疗科技有限公司 | 肥厚型心肌病变异基因alpk3及其应用 |
| WO2025010312A1 (en) * | 2023-07-06 | 2025-01-09 | The Regents Of The University Of California | Gene replacement therapy for alpk3 cardiomyopathy |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2792742A1 (en) * | 2013-04-17 | 2014-10-22 | Universitätsklinikum Hamburg-Eppendorf (UKE) | Gene-therapy vectors for treating cardiomyopathy |
| SG11201803934YA (en) * | 2015-11-11 | 2018-06-28 | Intrexon Corp | Compositions and methods for expression of multiple biologically active polypeptides from a single vector for treatment of cardiac conditions and other pathologies |
| WO2018208998A1 (en) * | 2017-05-10 | 2018-11-15 | The Regents Of The University Of California | Directed editing of cellular rna via nuclear delivery of crispr/cas9 |
| RU2770922C2 (ru) * | 2017-09-20 | 2022-04-25 | 4Д Молекьюлар Терапьютикс Инк. | Капсиды вариантов аденоассоциированных вирусов и методы их применения |
| ES2976559T3 (es) * | 2017-09-20 | 2024-08-05 | Univ California | Terapia génica con conexina 43 para restaurar la función eléctrica y cardíaca y la estructura cardíaca, en la miocardiopatía arritmogénica del ventrículo derecho |
| US20210363193A1 (en) * | 2018-04-27 | 2021-11-25 | Universität Heidelberg | Modified aav capsid polypeptides for treatment of muscular diseases |
| CN109004092A (zh) | 2018-06-29 | 2018-12-14 | 云谷（固安）科技有限公司 | 有机电致发光器件和有机电致发光装置 |
| KR20230043869A (ko) * | 2020-08-07 | 2023-03-31 | 스페이스크래프트 세븐, 엘엘씨 | Aav 벡터를 사용한 플라코필린-2(pkp2) 유전자 요법 |
-
2020
- 2020-09-21 TW TW109132629A patent/TWI897882B/zh active
- 2020-09-21 US US17/761,677 patent/US20220389452A1/en active Pending
- 2020-09-21 CA CA3151036A patent/CA3151036A1/en active Pending
- 2020-09-21 AU AU2020350140A patent/AU2020350140A1/en active Pending
- 2020-09-21 JP JP2022517343A patent/JP2022549140A/ja active Pending
- 2020-09-21 EP EP20776122.2A patent/EP4031672A1/en active Pending
- 2020-09-21 KR KR1020227012607A patent/KR20220066914A/ko active Pending
- 2020-09-21 WO PCT/EP2020/076290 patent/WO2021053222A1/en not_active Ceased
-
2022
- 2022-03-18 IL IL291488A patent/IL291488A/en unknown
-
2023
- 2023-11-07 US US18/503,557 patent/US20240076696A1/en not_active Abandoned
-
2025
- 2025-01-16 US US19/023,648 patent/US20250163470A1/en active Pending
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