JP2024526191A5 - - Google Patents

Info

Publication number
JP2024526191A5
JP2024526191A5 JP2023579304A JP2023579304A JP2024526191A5 JP 2024526191 A5 JP2024526191 A5 JP 2024526191A5 JP 2023579304 A JP2023579304 A JP 2023579304A JP 2023579304 A JP2023579304 A JP 2023579304A JP 2024526191 A5 JP2024526191 A5 JP 2024526191A5
Authority
JP
Japan
Prior art keywords
pharmaceutically acceptable
isotopolog
tautomer
stereoisomer
acceptable salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023579304A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024526191A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/034921 external-priority patent/WO2022272074A1/en
Publication of JP2024526191A publication Critical patent/JP2024526191A/ja
Publication of JP2024526191A5 publication Critical patent/JP2024526191A5/ja
Pending legal-status Critical Current

Links

JP2023579304A 2021-06-25 2022-06-24 セレブロン結合化合物、その組成物及びそれによる治療方法 Pending JP2024526191A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163215243P 2021-06-25 2021-06-25
US63/215,243 2021-06-25
PCT/US2022/034921 WO2022272074A1 (en) 2021-06-25 2022-06-24 Cereblon binding compounds, compositions thereof, and methods of treatment therewith

Publications (2)

Publication Number Publication Date
JP2024526191A JP2024526191A (ja) 2024-07-17
JP2024526191A5 true JP2024526191A5 (https=) 2025-06-30

Family

ID=84543920

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023579304A Pending JP2024526191A (ja) 2021-06-25 2022-06-24 セレブロン結合化合物、その組成物及びそれによる治療方法

Country Status (6)

Country Link
US (1) US20240368118A1 (https=)
EP (1) EP4359407A4 (https=)
JP (1) JP2024526191A (https=)
KR (1) KR20240026939A (https=)
CN (1) CN117561249A (https=)
WO (1) WO2022272074A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4692061A1 (en) * 2023-03-29 2026-02-11 Aevis Bio, Inc. Low-molecular-weight compound having cereblon-binding activity, and use thereof
AU2024298923A1 (en) 2023-07-25 2026-01-22 Monte Rosa Therapeutics Ag Substituted piperidinediones for targeted protein degradation

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6817962B2 (ja) * 2015-01-20 2021-01-20 アルビナス・オペレーションズ・インコーポレイテッドArvinas Operations, Inc. ターゲティングされたアンドロゲン受容体分解のための化合物および方法
TWI726969B (zh) * 2016-01-11 2021-05-11 比利時商健生藥品公司 用作雄性激素受體拮抗劑之經取代之硫尿囊素衍生物
IL312367A (en) * 2017-01-31 2024-06-01 Arvinas Operations Inc Cereblon ligands and bifunctional compounds comprising the same
EP3658548A1 (en) * 2017-07-28 2020-06-03 Arvinas Operations, Inc. Compounds and methods for the targeted degradation of androgen receptor
CN113453681B (zh) * 2018-12-19 2024-10-11 细胞基因公司 经取代的3-((3-氨基苯基)氨基)哌啶-2,6-二酮化合物、其组合物及使用它们的治疗方法
CN114521196A (zh) * 2019-09-16 2022-05-20 诺华股份有限公司 双官能团降解剂及其使用方法
KR20230027066A (ko) * 2020-06-24 2023-02-27 셀진 코포레이션 세레블론 결합 화합물, 이의 조성물, 및 이에 의한 치료 방법

Similar Documents

Publication Publication Date Title
JP2023533203A5 (https=)
JP2023531709A5 (https=)
JP2023531495A5 (https=)
JP2022512482A5 (https=)
JP2022520448A5 (https=)
JP2024520481A5 (https=)
WO2021203768A1 (zh) 嘧啶并二环类衍生物、其制备方法及其在医药上的应用
CN113365997A (zh) 作为c-Met抑制剂的含嘧啶基团的三并环类化合物
JP7759877B2 (ja) 治療用化合物
JP2022541467A (ja) オーロラキナーゼ阻害剤およびその使用
JP2024526191A5 (https=)
JP2021535207A5 (https=)
WO2019134539A1 (zh) 二氢吡唑酮并嘧啶类化合物及其制备方法和用途
JP2008509949A5 (https=)
JP2011509309A5 (https=)
JP2020063289A5 (https=)
JP2024516033A5 (https=)
JP2022534704A5 (https=)
JP2014514290A5 (https=)
JP7112755B2 (ja) Jak酵素阻害剤及びその製造方法と用途
JP2008513485A5 (https=)
JP2014520108A5 (https=)
CN115677664A (zh) 作为parp7抑制剂的哒嗪酮类化合物
AU2005335298A1 (en) N-phenyl-2-pyrimidine-amine derivatives and process for the preparation thereof
JP2007531766A5 (https=)