JP2008513485A5 - - Google Patents
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- Publication number
- JP2008513485A5 JP2008513485A5 JP2007532545A JP2007532545A JP2008513485A5 JP 2008513485 A5 JP2008513485 A5 JP 2008513485A5 JP 2007532545 A JP2007532545 A JP 2007532545A JP 2007532545 A JP2007532545 A JP 2007532545A JP 2008513485 A5 JP2008513485 A5 JP 2008513485A5
- Authority
- JP
- Japan
- Prior art keywords
- ring
- compound
- optionally substituted
- alkyl
- optionally
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 0 CC(*C=CN=C1C)=CC=C1I Chemical compound CC(*C=CN=C1C)=CC=C1I 0.000 description 20
- UZUMHXJDXINXJT-UHFFFAOYSA-N CC(N(CC1)CCN1c(cc1)nc(N(c2ccccc2N2C)C2=C2C(NCCN3CCCC3)=O)c1C2=O)=O Chemical compound CC(N(CC1)CCN1c(cc1)nc(N(c2ccccc2N2C)C2=C2C(NCCN3CCCC3)=O)c1C2=O)=O UZUMHXJDXINXJT-UHFFFAOYSA-N 0.000 description 1
- WMFHZGKRSJVEKA-UHFFFAOYSA-N CCN1C(CCNC(C2=C3Sc(ccc(Cl)c4)c4N3c(nc(cc3)N(CC4)CC4c4nccnc4)c3C2=O)=O)CCC1 Chemical compound CCN1C(CCNC(C2=C3Sc(ccc(Cl)c4)c4N3c(nc(cc3)N(CC4)CC4c4nccnc4)c3C2=O)=O)CCC1 WMFHZGKRSJVEKA-UHFFFAOYSA-N 0.000 description 1
- KJFAWEQQSCAKGS-UHFFFAOYSA-N NC(CC1)CN1c(c(F)c1)nc(N(c(cccc2)c2S2)C2=C2C(NCCN3CCCC3)=O)c1C2=O Chemical compound NC(CC1)CN1c(c(F)c1)nc(N(c(cccc2)c2S2)C2=C2C(NCCN3CCCC3)=O)c1C2=O KJFAWEQQSCAKGS-UHFFFAOYSA-N 0.000 description 1
- IALKVGMLLDHBRY-XCVCLJGOSA-N O=C(/C=C/CCN1CCCC1)C1=C2Sc(cccc3)c3N2c(nc(N2CCCC2)nc2)c2C1=O Chemical compound O=C(/C=C/CCN1CCCC1)C1=C2Sc(cccc3)c3N2c(nc(N2CCCC2)nc2)c2C1=O IALKVGMLLDHBRY-XCVCLJGOSA-N 0.000 description 1
- XBAGFKNPGOFRSS-UHFFFAOYSA-N O=C(C(C(c1c2)=O)=C3Sc(cccc4)c4N3c1cc(SCCc1nccnc1)c2F)NCCN1CCCC1 Chemical compound O=C(C(C(c1c2)=O)=C3Sc(cccc4)c4N3c1cc(SCCc1nccnc1)c2F)NCCN1CCCC1 XBAGFKNPGOFRSS-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US61103004P | 2004-09-17 | 2004-09-17 | |
| US63860304P | 2004-12-22 | 2004-12-22 | |
| US68898605P | 2005-06-09 | 2005-06-09 | |
| US68879605P | 2005-06-09 | 2005-06-09 | |
| US11/149,007 US7652134B2 (en) | 2004-09-17 | 2005-06-09 | Methods for converting quinolone esters into quinolone amides |
| PCT/US2005/033323 WO2006034113A2 (en) | 2004-09-17 | 2005-09-16 | Quinolone analogs as cell proliferation inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008513485A JP2008513485A (ja) | 2008-05-01 |
| JP2008513485A5 true JP2008513485A5 (https=) | 2008-10-30 |
Family
ID=35735203
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007532545A Ceased JP2008513485A (ja) | 2004-09-17 | 2005-09-16 | キノロンアナログ |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7816406B2 (https=) |
| EP (1) | EP1802306A2 (https=) |
| JP (1) | JP2008513485A (https=) |
| KR (1) | KR100989029B1 (https=) |
| AU (1) | AU2005286965B2 (https=) |
| BR (1) | BRPI0515319A (https=) |
| CA (1) | CA2580749C (https=) |
| IL (1) | IL181857A0 (https=) |
| MX (1) | MX2007003282A (https=) |
| NZ (1) | NZ553746A (https=) |
| WO (1) | WO2006034113A2 (https=) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1928887B1 (en) | 2005-08-05 | 2014-12-17 | Senhwa Biosciences, Inc. | Methods of preparing quinolone analogs |
| WO2007146831A2 (en) * | 2006-06-08 | 2007-12-21 | Cylene Pharmaceuticals, Inc. | Quinolone analogs derivatized with sulfonic acid, sulfonate or sulfonamide |
| WO2007146813A2 (en) * | 2006-06-08 | 2007-12-21 | Cylene Pharmaceuticals, Inc. | Pyridinone analogs as cell proliferation inhibitors |
| US7956064B2 (en) | 2006-09-01 | 2011-06-07 | Cylene Pharmaceuticals, Inc. | Fused tricyclic compounds as serine-threonine protein kinase and PARP modulators |
| US20080318939A1 (en) * | 2007-06-22 | 2008-12-25 | Whitten Jeffrey P | Methods for treating ophthalmic disorders |
| CN101801190A (zh) * | 2007-06-22 | 2010-08-11 | 赛林药物股份有限公司 | 治疗异常细胞增殖性疾病的方法 |
| WO2009097014A2 (en) * | 2007-08-31 | 2009-08-06 | Cylene Pharmaceuticals, Inc. | Therapeutic kinase modulators |
| EP2201010B1 (en) | 2007-09-14 | 2013-11-06 | Vertex Pharmaceuticals Incorporated | Modulators of cystic fibrosis transmembrane conductance regulator |
| PL3092901T3 (pl) * | 2007-10-05 | 2020-10-19 | Senhwa Biosciences, Inc. | Analogi chinolonu i sposoby z nimi związane |
| WO2011031745A1 (en) | 2009-09-09 | 2011-03-17 | Achaogen, Inc. | Antibacterial fluoroquinolone analogs |
| RU2435758C1 (ru) * | 2010-07-19 | 2011-12-10 | Государственное образовательное учреждение высшего профессионального образования Волгоградский государственный технический университет (ВолгГТУ) | Способ получения этилового эфира 3-оксо-3-(2,6-дихлорпиридин-3-ил) пропановой кислоты |
| US9758518B2 (en) | 2015-03-04 | 2017-09-12 | Pimera, Inc. | Compositions, uses and methods for making them |
| PL3140305T3 (pl) | 2014-05-09 | 2018-10-31 | Pimera, Inc. | Nowe kompozycje, ich zastosowania i sposoby wytwarzania |
| WO2016137471A1 (en) * | 2015-02-26 | 2016-09-01 | Nantpharma, Llc | Method for enhanced heparin quality |
| WO2017087235A1 (en) | 2015-11-20 | 2017-05-26 | Senhwa Biosciences, Inc. | Combination therapy of tetracyclic quinolone analogs for treating cancer |
| JP2018537486A (ja) * | 2015-12-14 | 2018-12-20 | センワ バイオサイエンシズ インコーポレイテッド | キノロン類似体及びその塩の結晶形 |
| US9957282B2 (en) | 2015-12-14 | 2018-05-01 | Senhwa Biosciences, Inc. | Crystalline forms of quinolone analogs and their salts |
| CA3057741A1 (en) | 2017-03-28 | 2018-10-04 | Pimera, Inc. | Novel crystal forms of a pol1 inhibitor |
| TWI884912B (zh) | 2018-02-15 | 2025-06-01 | 生華生物科技股份有限公司 | 喹啉酮類似物及其鹽、組合物及其使用方法 |
| JP2020189888A (ja) * | 2020-08-28 | 2020-11-26 | センワ バイオサイエンシズ インコーポレイテッド | キノロン類似体及びその塩の結晶形 |
| WO2025114459A1 (en) * | 2023-11-28 | 2025-06-05 | Genome Therapeutics Ltd | Tetracyclic compounds for use in antibody-drug conjugates for the treatment of cancer |
| WO2025242908A2 (en) * | 2024-05-24 | 2025-11-27 | Genome Therapeutics Ltd | Novel compounds |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2808070A1 (de) * | 1978-02-24 | 1979-08-30 | Bayer Ag | Verfahren zur herstellung von 4-pyridon-3-carbonsaeuren und/oder deren derivaten |
| DE3267485D1 (en) | 1981-02-18 | 1986-01-02 | Nippon Shinyaku Co Ltd | Substituted carboxylic acid derivatives |
| ZA852769B (en) * | 1984-04-26 | 1985-11-27 | Abbott Lab | Benzothiazolo-quinoline antibacterial compounds |
| ZA852802B (en) * | 1984-04-26 | 1985-11-27 | Abbott Lab | Benzoxazolo-quinoline antibacterial compounds |
| US4528285A (en) * | 1984-04-26 | 1985-07-09 | Abbott Laboratories | Methylenedioxy quino-benzothiazine derivatives |
| WO1989012055A1 (fr) | 1988-06-08 | 1989-12-14 | Kyorin Pharmaceutical Co., Ltd. | Agent antitumoral |
| US4959363A (en) * | 1989-06-23 | 1990-09-25 | Sterling Drug Inc. | Quinolonecarboxamide compounds, their preparation and use as antivirals. |
| IE912902A1 (en) | 1990-08-24 | 1992-02-26 | Abbott Lab | Quinbenzoxazine, quinobenzothiazine, and pyrido-acridine¹antineoplastic agents |
| JPH04117388A (ja) * | 1990-09-07 | 1992-04-17 | Hokuriku Seiyaku Co Ltd | チアゾロキノリン―４―カルボン酸誘導体 |
| US5646163A (en) * | 1992-10-30 | 1997-07-08 | The Procter & Gamble Company | Quinolone 5-(N-heterosubstituted amino) antimicrobials |
| GB9402275D0 (en) * | 1994-02-07 | 1994-03-30 | Fujisawa Pharmaceutical Co | Quinoline derivatives |
| US6559145B2 (en) * | 2000-07-12 | 2003-05-06 | Pharmacia & Upjohn Company | Heterocycle carboxamides as antiviral agents |
| US6699989B1 (en) | 2000-08-28 | 2004-03-02 | B. Vithal Shetty | Antiviral and antimicrobial guanidine or biguanidine derivatives |
| DE60113450T2 (de) * | 2000-12-14 | 2006-07-13 | The Procter & Gamble Company, Cincinnati | Antimikrobielle chinolone |
| US6821969B2 (en) * | 2001-02-13 | 2004-11-23 | Pharmacia & Upjohn Company | Thioxazinoquinolones as antiviral agents |
| US6900224B2 (en) | 2002-07-31 | 2005-05-31 | The Procter & Gamble Company | Antimicrobial quinolones, their compositions and uses |
| EP1610759A4 (en) | 2003-04-07 | 2007-04-25 | Cylene Pharmaceuticals Inc | SUBSTITUTED CHINOBENZOXAZINE ANALOGUE |
| CN104324029A (zh) * | 2004-03-15 | 2015-02-04 | 逊尼希思制药公司 | Sns-595及其使用方法 |
-
2005
- 2005-09-16 EP EP05813754A patent/EP1802306A2/en not_active Withdrawn
- 2005-09-16 BR BRPI0515319-0A patent/BRPI0515319A/pt not_active IP Right Cessation
- 2005-09-16 MX MX2007003282A patent/MX2007003282A/es not_active Application Discontinuation
- 2005-09-16 US US11/228,636 patent/US7816406B2/en active Active
- 2005-09-16 CA CA2580749A patent/CA2580749C/en not_active Expired - Lifetime
- 2005-09-16 WO PCT/US2005/033323 patent/WO2006034113A2/en not_active Ceased
- 2005-09-16 JP JP2007532545A patent/JP2008513485A/ja not_active Ceased
- 2005-09-16 KR KR1020077008765A patent/KR100989029B1/ko not_active Expired - Fee Related
- 2005-09-16 NZ NZ553746A patent/NZ553746A/en not_active IP Right Cessation
- 2005-09-16 AU AU2005286965A patent/AU2005286965B2/en not_active Expired
-
2007
- 2007-03-12 IL IL181857A patent/IL181857A0/en unknown
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