JP2024523466A5 - - Google Patents
Info
- Publication number
- JP2024523466A5 JP2024523466A5 JP2023578896A JP2023578896A JP2024523466A5 JP 2024523466 A5 JP2024523466 A5 JP 2024523466A5 JP 2023578896 A JP2023578896 A JP 2023578896A JP 2023578896 A JP2023578896 A JP 2023578896A JP 2024523466 A5 JP2024523466 A5 JP 2024523466A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleotides
- positions
- chain
- antisense
- sense
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163213506P | 2021-06-22 | 2021-06-22 | |
| US63/213,506 | 2021-06-22 | ||
| US202263331563P | 2022-04-15 | 2022-04-15 | |
| US63/331,563 | 2022-04-15 | ||
| PCT/US2022/034297 WO2022271666A1 (en) | 2021-06-22 | 2022-06-21 | OLIGONUCLEOTIDES FOR IFN-γ SIGNALING PATHWAY MODULATION |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024523466A JP2024523466A (ja) | 2024-06-28 |
| JP2024523466A5 true JP2024523466A5 (https=) | 2025-07-01 |
Family
ID=84544753
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023578896A Pending JP2024523466A (ja) | 2021-06-22 | 2022-06-21 | IFN-γシグナル伝達経路の調節のためのオリゴヌクレオチド |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20240287514A1 (https=) |
| EP (1) | EP4359537A4 (https=) |
| JP (1) | JP2024523466A (https=) |
| KR (1) | KR20240040724A (https=) |
| AU (1) | AU2022298641A1 (https=) |
| CA (1) | CA3223577A1 (https=) |
| WO (1) | WO2022271666A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021242883A1 (en) | 2020-05-26 | 2021-12-02 | University Of Massachusetts | Synthetic oligonucleotides having regions of block and cluster modifications |
| EP4676443A1 (en) * | 2023-03-03 | 2026-01-14 | University of Massachusetts | Dendritic conjugates for the skin delivery of therapeutic oligonucleotides |
| TW202516004A (zh) * | 2023-06-16 | 2025-04-16 | 瑞士商赫孚孟拉羅股份公司 | 調節jak1表現之雙股寡核苷酸 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006094293A2 (en) * | 2005-03-03 | 2006-09-08 | President And Fellows Of Harvard College | Slim compositions and methods of use thereof |
| EP2227558A1 (en) * | 2007-11-30 | 2010-09-15 | GlaxoSmithKline Biologicals SA | Method for classifying cancer patients as responder or non-responder to immunotherapy |
| JP5813778B2 (ja) * | 2010-11-19 | 2015-11-17 | イデラ ファーマシューティカルズ インコーポレイテッドIdera Pharmaceuticals, Inc. | トール様受容体に基づく免疫反応を調節するための免疫調節オリゴヌクレオチド(iro)化合物 |
| CN113811311A (zh) * | 2019-03-15 | 2021-12-17 | 马萨诸塞大学 | 用于组织特异性apoe调节的寡核苷酸 |
-
2022
- 2022-06-21 WO PCT/US2022/034297 patent/WO2022271666A1/en not_active Ceased
- 2022-06-21 CA CA3223577A patent/CA3223577A1/en active Pending
- 2022-06-21 AU AU2022298641A patent/AU2022298641A1/en active Pending
- 2022-06-21 KR KR1020247000555A patent/KR20240040724A/ko active Pending
- 2022-06-21 JP JP2023578896A patent/JP2024523466A/ja active Pending
- 2022-06-21 EP EP22829131.6A patent/EP4359537A4/en active Pending
-
2023
- 2023-12-21 US US18/393,044 patent/US20240287514A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2024523466A5 (https=) | ||
| JP2021533804A5 (https=) | ||
| JP7129702B2 (ja) | オーバーハングを有する二本鎖核酸複合体 | |
| JP2023522701A5 (https=) | ||
| JP2022528487A5 (https=) | ||
| AU2002345089B2 (en) | Synthetic double stranded oligonucleotides for targeted inhibition of gene expression | |
| JP2023518439A5 (https=) | ||
| JP2019503394A5 (https=) | ||
| JP2023550485A5 (https=) | ||
| JP2022525208A5 (https=) | ||
| JP2021533762A5 (https=) | ||
| WO2017062862A2 (en) | Oligonucleotide compositions and methods thereof | |
| JP2023518268A5 (https=) | ||
| JPH09510714A (ja) | オリゴヌクレオチドn3’→p5’ホスホルアミデート:合成および化合物;ハイブリダイゼーションおよびヌクレアーゼ耐性特性 | |
| KR20020033744A (ko) | 사람 eg5의 발현을 억제하는 올리고뉴클레오티드 | |
| CN105121452A (zh) | 三环核苷和由其制备的寡聚化合物 | |
| CN104321334A (zh) | 三环核苷及由其制备的低聚化合物 | |
| JP2025156522A (ja) | 修飾ヘテロ核酸 | |
| EP2781523A1 (en) | Lipophilic oligonucleotide analogs | |
| JP7737667B2 (ja) | 核酸複合体 | |
| JP6882735B2 (ja) | 構造強化されたmiRNA阻害剤S−TuD | |
| CA2609365C (en) | Stable and selective formation of hoogsteen-type triplexes and duplexes using twisted intercalating nucleic acids (tina) and process for the preparation of tina | |
| WO2024040041A1 (en) | Regulation of activity of rnai molecules | |
| JP6934695B2 (ja) | 核酸医薬とその使用 | |
| Rejman et al. | Synthesis and hybridization of oligonucleotides modified at AMP sites with adenine pyrrolidine phosphonate nucleotides |