JP2024522116A5 - - Google Patents

Info

Publication number
JP2024522116A5
JP2024522116A5 JP2023573353A JP2023573353A JP2024522116A5 JP 2024522116 A5 JP2024522116 A5 JP 2024522116A5 JP 2023573353 A JP2023573353 A JP 2023573353A JP 2023573353 A JP2023573353 A JP 2023573353A JP 2024522116 A5 JP2024522116 A5 JP 2024522116A5
Authority
JP
Japan
Prior art keywords
cancer cells
antibody construct
antibody
muc1
construct according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023573353A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024522116A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/031431 external-priority patent/WO2022251695A2/en
Publication of JP2024522116A publication Critical patent/JP2024522116A/ja
Publication of JP2024522116A5 publication Critical patent/JP2024522116A5/ja
Pending legal-status Critical Current

Links

JP2023573353A 2021-05-28 2022-05-27 Muc1-c/細胞外ドメイン(muc1-c/ecd)に対する多重特異性抗体構築物 Pending JP2024522116A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163194597P 2021-05-28 2021-05-28
US63/194,597 2021-05-28
PCT/US2022/031431 WO2022251695A2 (en) 2021-05-28 2022-05-27 Multi-specific antibody constructs against the muc1-c/extracellular domain ( muc1-c/ecd)

Publications (2)

Publication Number Publication Date
JP2024522116A JP2024522116A (ja) 2024-06-11
JP2024522116A5 true JP2024522116A5 (enExample) 2025-05-02

Family

ID=84230363

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023573353A Pending JP2024522116A (ja) 2021-05-28 2022-05-27 Muc1-c/細胞外ドメイン(muc1-c/ecd)に対する多重特異性抗体構築物

Country Status (11)

Country Link
US (1) US20240262930A1 (enExample)
EP (1) EP4346890A4 (enExample)
JP (1) JP2024522116A (enExample)
KR (1) KR20240021828A (enExample)
CN (1) CN117769432A (enExample)
AU (1) AU2022283436A1 (enExample)
BR (1) BR112023024724A2 (enExample)
CA (1) CA3220049A1 (enExample)
IL (1) IL308881A (enExample)
MX (1) MX2023014109A (enExample)
WO (1) WO2022251695A2 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4644413A1 (en) * 2024-05-03 2025-11-05 Genmab B.V. Binding agents having altered fc-mediated effector functions
WO2026024841A1 (en) * 2024-07-24 2026-01-29 Astellas Us Llc Bispecific antibodies that bind cd3 and muc1 and methods of use thereof

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080279850A1 (en) * 2005-07-25 2008-11-13 Trubion Pharmaceuticals, Inc. B-Cell Reduction Using CD37-Specific and CD20-Specific Binding Molecules
NZ573646A (en) * 2006-06-12 2012-04-27 Wyeth Llc Single-chain multivalent binding proteins with effector function
EP2604279A1 (en) * 2008-03-27 2013-06-19 ZymoGenetics, Inc. Compositions and methods for inhibiting PDGFRBETA and VEGF-A
JP2012530721A (ja) * 2009-06-18 2012-12-06 ワイス・エルエルシー 小モジュール免疫薬のための凍結乾燥製剤
US20130189268A1 (en) * 2010-06-22 2013-07-25 Precision Biologics, Inc. Colon and pancreas cancer specific antigens and antibodies
US20150038682A1 (en) * 2013-08-02 2015-02-05 Jn Biosciences Llc Antibodies or fusion proteins multimerized via homomultimerizing peptide
WO2015116753A1 (en) * 2014-01-29 2015-08-06 Dana-Farber Cancer Institute, Inc. Antibodies against the muc1-c/extracellular domain (muc1-c/ecd)
US10617773B2 (en) * 2016-08-05 2020-04-14 Dana-Farber Cancer Institute, Inc. Antibodies against the MUC1-C/extracellular domain (MUC1-C/ECD)
WO2018178047A1 (en) * 2017-03-29 2018-10-04 Glycotope Gmbh Multispecific antibody constructs binding to muc1 and cd3
EP3655439A1 (en) * 2017-07-20 2020-05-27 Aptevo Research and Development LLC Antigen binding proteins binding to 5t4 and 4-1bb and related compositions and methods
JP2021502100A (ja) * 2017-11-08 2021-01-28 ゼンコア インコーポレイテッド 新規抗pd−1配列を用いた二重特異性および単一特異性抗体
SG11202008474QA (en) * 2018-03-27 2020-10-29 Systimmune Inc Guidance and navigation control proteins and method of making and using thereof
US20210115152A1 (en) * 2018-05-16 2021-04-22 Arbele Limited Composition of bispecific antibodies and method of use thereof
JP7495409B2 (ja) * 2018-09-11 2024-06-04 ドイチェス クレブスフォルシュングスツェントルム シュティフトゥング デス エッフェントリッヒェンレヒツ 改善された抗flt3抗原結合タンパク質

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